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  1. Article ; Online: Scientists' expertise as performance: between state and society, 1860-1960.

    Leggett, Don

    Annals of science

    2017  Volume 74, Issue 1, Page(s) 84–86

    Language English
    Publishing date 2017-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 337-2
    ISSN 1464-505X ; 0003-4924 ; 0003-3790
    ISSN (online) 1464-505X
    ISSN 0003-4924 ; 0003-3790
    DOI 10.1080/00033790.2016.1257737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 73/720: Show issues

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  2. Article: Restoring Victory: Naval Heritage, Identity, and Memory in Interwar Britain.

    Leggett, Don

    20 century British history

    2017  Volume 28, Issue 1, Page(s) 57–82

    Abstract: In the decade following 1918, HMS Victory was restored as a memorial to the nation, empire, the Navy, and all the sailors who had lost their lives in the Great War. This piece of Britain's naval heritage became a focal point for Great War memory and a ... ...

    Abstract In the decade following 1918, HMS Victory was restored as a memorial to the nation, empire, the Navy, and all the sailors who had lost their lives in the Great War. This piece of Britain's naval heritage became a focal point for Great War memory and a resource for narrating the Navy's place in post-war Britain. This article analyses the restoration campaign, focusing on its appeal work and the materials it produced, discourses surrounding the restoration and the use of Victory's oak to recover this ship's importance at the intersection between Britain and its Navy in the aftermath of the Great War, and the function that the Navy played in the construction of post-war memory and identity.
    Language English
    Publishing date 2017-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077480-1
    ISSN 1477-4674 ; 0955-2359
    ISSN (online) 1477-4674
    ISSN 0955-2359
    DOI 10.1093/tcbh/hww060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Whether to screen, or who to screen, that is the question.

    Codipilly, Don C / Rubenstein, Joel H / Leggett, Cadman L

    Gastrointestinal endoscopy

    2021  Volume 95, Issue 2, Page(s) 236–238

    MeSH term(s) Humans ; Mass Screening ; Surveys and Questionnaires
    Language English
    Publishing date 2021-12-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2021.10.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 519: Show issues

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  4. Book: Scientific governance in Britain, 1914-79

    Leggett, Don / Sleigh, Charlotte

    2016  

    Author's details edited by Don Leggett and Charlotte Sleigh
    MeSH term(s) Science/history ; Science/organization & administration ; History, 20th Century
    Keywords United Kingdom
    Language English
    Dates of publication 2016-2016
    Size xx, 323 pages ;, 23 cm
    Document type Book
    ISBN 9780719090981 ; 0719090989
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Book ; Online: Re-inventing the Ship

    Leggett, Don / Dunn, Richard

    Science, Technology and the Maritime World, 1800-1918

    (Corbett Centre for Maritime Policy Studies Series)

    2012  

    Abstract: The technological development of the ship between 1800 and 1914 was dramatic, encompassing the shift from wood and sail to iron, steel and steam. This volume offers a multi-disciplinary approach to the history of the ship in the long nineteenth century. ... ...

    Series title Corbett Centre for Maritime Policy Studies Series
    Abstract The technological development of the ship between 1800 and 1914 was dramatic, encompassing the shift from wood and sail to iron, steel and steam. This volume offers a multi-disciplinary approach to the history of the ship in the long nineteenth century. It illustrates the ways in which the material elements of the ship, together with the scientific, artisan and seafaring ideas and practices that endowed the ship with its character, may be approached from different historical, geographical, cultural and literary perspectives
    Language English
    Size Online-Ressource (241 p.)
    Publisher Ashgate Publishing Ltd
    Publishing place Farnham
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781409418498 ; 1409418499
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Article ; Online: Epidemiology and Outcomes of Young-Onset Esophageal Adenocarcinoma: An Analysis from a Population-Based Database.

    Codipilly, Don C / Sawas, Tarek / Dhaliwal, Lovekirat / Johnson, Michele L / Lansing, Ramona / Wang, Kenneth K / Leggett, Cadman L / Katzka, David A / Iyer, Prasad G

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

    2020  Volume 30, Issue 1, Page(s) 142–149

    Abstract: Background: Esophageal adenocarcinoma is a lethal cancer with rising incidence. There are limited data in younger (<50 years) patients with esophageal adenocarcinoma. We aimed to assess time trends in the incidence and outcomes of "young-onset" ... ...

    Abstract Background: Esophageal adenocarcinoma is a lethal cancer with rising incidence. There are limited data in younger (<50 years) patients with esophageal adenocarcinoma. We aimed to assess time trends in the incidence and outcomes of "young-onset" esophageal adenocarcinoma using a population-based database.
    Methods: We queried the Surveillance, Epidemiology, and End Results 9 database to identify patients with esophageal adenocarcinoma between 1975 and 2015. Patients were stratified into three age strata: <50, 50 to 69, and ≥70 years. Staging was stratified as localized, regional, and distant. Trends in incidence, disease stage, and survival were assessed in three periods (1975-89, 1990-99, and 2000-2015). Univariate and multivariate models were created to identify predictors of mortality.
    Results: Esophageal adenocarcinoma incidence has increased in patients <50 years of age, with an annual percentage change of 2.9% (95% confidence interval, 1.4%-4.4%) from 1975 to 2015. Young-onset esophageal adenocarcinoma presented at more advanced stages (regional + distant) compared with older patients (84.9% vs. 67.3%;
    Conclusions: Young-onset esophageal adenocarcinoma, while uncommon, is rising in incidence. Concerningly, the proportion of advanced disease continues to increase. Young-onset esophageal adenocarcinoma also presents at more advanced stages, resulting in poorer esophageal adenocarcinoma-free survival.
    Impact: Patients with esophageal adenocarcinoma younger than 50 years present at more advanced stages with higher esophageal adenocarcinoma-specific mortality compared with older peers. Current diagnostic and management strategies for young-onset esophageal adenocarcinoma may need to be reevaluated.
    MeSH term(s) Adenocarcinoma/mortality ; Adenocarcinoma/therapy ; Adult ; Age Distribution ; Age of Onset ; Aged ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/therapy ; Female ; Humans ; Incidence ; Kaplan-Meier Estimate ; Male ; Middle Aged ; SEER Program ; Sex Distribution
    Language English
    Publishing date 2020-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1153420-5
    ISSN 1538-7755 ; 1055-9965
    ISSN (online) 1538-7755
    ISSN 1055-9965
    DOI 10.1158/1055-9965.EPI-20-0944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3693: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Occupational Intakes of Radionuclides: Part 5.

    Paquet, F / Leggett, R W / Blanchardon, E / Bailey, M R / Gregoratto, D / Smith, T / Ratia, G / Davesne, E / Berkovski, V / Harrison, J D

    Annals of the ICRP

    2022  Volume 51, Issue 1-2, Page(s) 11–415

    MeSH term(s) Radiation Dosage ; Radiation Exposure ; Radiation Protection ; Radioisotopes
    Chemical Substances Radioisotopes
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Editorial
    ISSN 1872-969X ; 0146-6453
    ISSN (online) 1872-969X
    ISSN 0146-6453
    DOI 10.1177/01466453211028755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optimizing Value From Cardiac Rehabilitation: A Cost-Utility Analysis Comparing Age, Sex, and Clinical Subgroups.

    Leggett, Laura E / Hauer, Trina / Martin, Billie-Jean / Manns, Braden / Aggarwal, Sandeep / Arena, Ross / Austford, Leslie D / Meldrum, Don / Ghali, William / Knudtson, Merril L / Norris, Colleen M / Stone, James A / Clement, Fiona

    Mayo Clinic proceedings

    2015  Volume 90, Issue 8, Page(s) 1011–1020

    Abstract: Objective: To assess the cost utility of a center-based outpatient cardiac rehabilitation program compared with no program within patient subgroups on the basis of age, sex, and clinical presentation (acute coronary syndrome [ACS] or non-ACS).: ... ...

    Abstract Objective: To assess the cost utility of a center-based outpatient cardiac rehabilitation program compared with no program within patient subgroups on the basis of age, sex, and clinical presentation (acute coronary syndrome [ACS] or non-ACS).
    Methods: We performed a cost-utility analysis from a health system payer perspective to compare cardiac rehabilitation with no cardiac rehabilitation for patients who had a cardiac catheterization. The Markov model was stratified by clinical presentation, age, and sex. Clinical, quality-of-life, and cost data were provided by the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease and TotalCardiology.
    Results: The incremental cost per quality-adjusted life-year (QALY) gained for cardiac rehabilitation varies by subgroup, from $18,101 per QALY gained to $104,518 per QALY gained. There is uncertainty in the estimates due to uncertainty in the clinical effectiveness of cardiac rehabilitation. Overall, the probabilistic sensitivity analysis found that 75% of the time participation in cardiac rehabilitation is more expensive but more effective than not participating in cardiac rehabilitation.
    Conclusion: The cost-effectiveness of cardiac rehabilitation varies depending on patient characteristics. The current analysis indicates that cardiac rehabilitation is most cost effective for those with an ACS and those who are at higher risk for subsequent cardiac events. The findings of the current study provide insight into who may benefit most from cardiac rehabilitation, with important implications for patient referral patterns.
    MeSH term(s) Acute Coronary Syndrome/complications ; Acute Coronary Syndrome/mortality ; Acute Coronary Syndrome/therapy ; Age Factors ; Aged ; Cardiac Catheterization ; Cohort Studies ; Cost-Benefit Analysis ; Female ; Humans ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/mortality ; Myocardial Infarction/therapy ; Outcome Assessment (Health Care) ; Quality-Adjusted Life Years ; Rehabilitation Centers/economics ; Risk Factors ; Sex Factors
    Language English
    Publishing date 2015-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2015.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.183: Show issues Location:
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  9. Article ; Online: Acceptability of the Brushing RemInder 4 Good oral HealTh (BRIGHT) trial intervention: a qualitative study of perspectives of young people and school staff.

    Elyousfi, Sarab / Innes, Nicola / Leggett, Heather / Ainsworth, Hannah / Chestnutt, Ivor G / Day, Peter / Robertson, Mark / Pavitt, Sue / Kellar, Ian / Dey, Donna / Marshman, Zoe

    BMC oral health

    2022  Volume 22, Issue 1, Page(s) 44

    Abstract: Background: The Brushing RemInder 4 Good oral HealTh (BRIGHT) trial is investigating the clinical and cost-effectiveness of a multi-component behaviour change intervention to reduce the prevalence of dental caries in young people from deprived areas ... ...

    Abstract Background: The Brushing RemInder 4 Good oral HealTh (BRIGHT) trial is investigating the clinical and cost-effectiveness of a multi-component behaviour change intervention to reduce the prevalence of dental caries in young people from deprived areas aged 11-13 years. Mobile health has gained popularity in delivering behaviour change interventions for improving oral health. The intervention, based on behaviour change theory, consists of two components; a single classroom-based session embedded in the school curriculum and a series of follow-up text messages (SMS) delivered twice daily to participants. This element of the process evaluation aimed to explore the acceptability of the BRIGHT intervention for pupils and school staff.
    Methods: Qualitative study, based on the concept of acceptability. Focus groups were conducted with 50 pupils, from six secondary schools across the UK, who had received the intervention. Semi-structured interviews were conducted with 12 members of staff. Purposive maximum variation sampling was used. Interviews were transcribed verbatim and analysed using a framework approach.
    Results: In line with the theoretical framework of acceptability, affective attitude, perceived effectiveness, ethicality, burden and self-efficacy were identified as factors that affect the acceptability of the BRIGHT intervention. Pupil participants appreciated learning about the consequences of inadequate brushing particularly the photographs of carious teeth during the classroom-based session. More detailed information on brushing techniques and follow-up lessons on oral health were recommended by pupils. In terms of the SMS, the data suggest that pupil participants found them to be helpful reminders for brushing their teeth. To further improve acceptability, more choice over the timing of the messages and greater interactivity to reduce tedium were suggested. Staff participants recognised the value of the lesson and reported that in general the content was suitable for their pupils. Having the lesson material prepared for them, having the necessary support and whether it was included in the curriculum, were factors that improved acceptability.
    Conclusion: Overall, pupils and staff found the BRIGHT intervention acceptable and made some suggestions which could be adopted in any subsequent implementation of the intervention.
    MeSH term(s) Adolescent ; Child ; Clinical Trials as Topic ; Dental Caries/prevention & control ; Humans ; Oral Health ; Qualitative Research ; Schools ; Toothbrushing
    Language English
    Publishing date 2022-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-022-02073-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: ICRP Publication 141: Occupational Intakes of Radionuclides: Part 4.

    Paquet, F / Bailey, M R / Leggett, R W / Etherington, G / Blanchardon, E / Smith, T / Ratia, G / Melo, D / Fell, T P / Berkovski, V / Harrison, J D

    Annals of the ICRP

    2019  Volume 48, Issue 2-3, Page(s) 9–501

    MeSH term(s) Dose-Response Relationship, Radiation ; Humans ; Occupational Exposure/prevention & control ; Radiation Exposure/prevention & control ; Radiation Exposure/standards ; Radiation Monitoring/standards ; Radiation Protection/standards ; Radiation, Ionizing ; Radioisotopes/adverse effects ; Risk Assessment
    Chemical Substances Radioisotopes
    Language English
    Publishing date 2019-12-18
    Publishing country England
    Document type Journal Article
    ISSN 1872-969X ; 0146-6453
    ISSN (online) 1872-969X
    ISSN 0146-6453
    DOI 10.1177/0146645319834139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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