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  1. Article: Involving patients in treatment decisions, disease management and research for end-stage kidney disease.

    Jager, Kitty J / van der Veer, Sabine N

    Clinical kidney journal

    2023  Volume 16, Issue Suppl 1, Page(s) i1–i3

    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Editorial
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad171
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  2. Article: A new methodological series in

    Zoccali, Carmine / Stel, Vianda / Dekker, Friedo / Jager, Kitty J

    Clinical kidney journal

    2023  Volume 16, Issue 12, Page(s) 2303

    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad187
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  3. Article ; Online: Erratum to: Relative risk versus absolute risk: one cannot be interpreted without the other.

    Noordzij, Marlies / van Diepen, Merel / Caskey, Fergus C / Jager, Kitty J

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2022  Volume 37, Issue 5, Page(s) 1001

    Language English
    Publishing date 2022-02-08
    Publishing country England
    Document type Published Erratum
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfab291
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  4. Article ; Online: Differences in the epidemiology, management and outcomes of kidney disease in men and women.

    Chesnaye, Nicholas C / Carrero, Juan Jesus / Hecking, Manfred / Jager, Kitty J

    Nature reviews. Nephrology

    2023  Volume 20, Issue 1, Page(s) 7–20

    Abstract: Improved understanding of differences in kidney disease epidemiology, management and outcomes in men and women could help nephrologists to better meet the needs of their patients from a sex- and gender-specific perspective. Evidence of sex differences in ...

    Abstract Improved understanding of differences in kidney disease epidemiology, management and outcomes in men and women could help nephrologists to better meet the needs of their patients from a sex- and gender-specific perspective. Evidence of sex differences in the risk and outcomes of acute kidney injury is mixed and dependent on aetiology. Women have a higher prevalence of chronic kidney disease (CKD) stages 3-5 than men, whereas men have a higher prevalence of albuminuria and hence CKD stages 1-2. Men show a faster decline in kidney function, progress more frequently to kidney failure and have higher mortality and risk of cardiovascular disease than women. However, the protective effect of female sex is reduced with CKD progression. Women are less likely than men to be aware of, screened for and diagnosed with CKD, started on antiproteinuric medication and referred to nephrologist care. They also consistently report a poorer health-related quality of life and a higher symptom burden than men. Women experience greater barriers than men to access the waiting list for kidney transplantation, particularly with respect to older age and obesity. However, women also have longer survival than men after transplantation, which may partly explain the comparable prevalence of transplantation between the sexes.
    MeSH term(s) Humans ; Female ; Male ; Quality of Life ; Disease Progression ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/therapy ; Renal Insufficiency, Chronic/etiology ; Kidney Transplantation/adverse effects ; Cardiovascular Diseases ; Glomerular Filtration Rate
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/s41581-023-00784-z
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  5. Article: A new series of advanced-level research methods papers.

    Jager, Kitty J / Dekker, Friedo W / Zoccali, Carmine

    Clinical kidney journal

    2020  Volume 13, Issue 2, Page(s) 142

    Language English
    Publishing date 2020-04-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfaa038
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  6. Article ; Online: Sex differences in CKD risk factors across ethnic groups.

    Vosters, Taryn G / Kingma, Frouke M / Stel, Vianda S / van den Born, Bert-Jan H / Huisman, Brechje J M V / van Ittersum, Frans J / Jager, Kitty J / Vogt, Liffert / van Valkengoed, Irene

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae038
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  7. Article ; Online: A toolkit for ISN's registry initiative, SharE-RR.

    Pippias, Maria / Abeysekera, Rajitha A / Arruebo, Silvia / Davids, M Razeen / Damster, Sandrine / Gonzales-Bedat, Maria C / Hanafusa, Norio / Hoshino, Junichi / Hradsky, Anne / Irish, Georgina L / Jager, Kitty J / Karam, Sabine / Kumar, Vivek / McDonald, Stephen P / Rosa-Diez, Guillermo J / Tannor, Elliot K / Wetmore, James B / Caskey, Fergus J

    Kidney international

    2024  Volume 105, Issue 4, Page(s) 646–648

    MeSH term(s) Registries ; Nephrology
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2024.02.002
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  8. Article ; Online: Growth in children on kidney replacement therapy: a review of data from patient registries.

    Bonthuis, Marjolein / Harambat, Jérôme / Jager, Kitty J / Vidal, Enrico

    Pediatric nephrology (Berlin, Germany)

    2021  Volume 36, Issue 8, Page(s) 2563–2574

    Abstract: Growth retardation is a major complication in children with chronic kidney disease (CKD) and on kidney replacement therapy (KRT). Conversely, better growth in childhood CKD is associated with an improvement in several hard morbidity-mortality endpoints. ... ...

    Abstract Growth retardation is a major complication in children with chronic kidney disease (CKD) and on kidney replacement therapy (KRT). Conversely, better growth in childhood CKD is associated with an improvement in several hard morbidity-mortality endpoints. Data from pediatric international registries has demonstrated that improvements in the overall conservative management of CKD, the search for optimal dialysis, and advances in immunosuppression and kidney transplant techniques have led to a significant improvement of final height over time. Infancy still remains a critical period for adequate linear growth, and the loss of stature during the first years of life influences final height. Preliminary new original data from the European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association (ESPN/ERA-EDTA) Registry confirm an association between the final height and the height attained at 2 years in children on KRT.
    MeSH term(s) Child ; Humans ; Kidney Failure, Chronic/therapy ; Kidney Transplantation/adverse effects ; Registries ; Renal Dialysis ; Renal Insufficiency, Chronic ; Renal Replacement Therapy
    Language English
    Publishing date 2021-06-18
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-021-05099-4
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  9. Article ; Online: European nephrologists' views on remote patient management for end-stage kidney disease.

    de Jong, Rianne W / Jager, Kitty J / Broens, Tom H F / Stel, Vianda S

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2021  Volume 37, Issue 1, Page(s) 194–196

    MeSH term(s) Attitude of Health Personnel ; Humans ; Kidney Failure, Chronic/therapy ; Nephrologists ; Nephrology ; Renal Dialysis
    Language English
    Publishing date 2021-06-24
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfab206
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  10. Article: The long-term benefits of early intensive therapy in chronic diseases-the legacy effect.

    Zoccali, Carmine / Mallamaci, Francesca / Tripepi, Giovanni / Fu, Edouard L / Stel, Vianda S / Dekker, Friedo W / Jager, Kitty J

    Clinical kidney journal

    2023  Volume 16, Issue 11, Page(s) 1917–1924

    Abstract: The 'legacy effect' refers to the long-term benefits of intensive therapy that are observed long after the end of clinical trials and trial interventions in chronic diseases such as diabetes, hyperlipidaemia and hypertension. It emphasizes the importance ...

    Abstract The 'legacy effect' refers to the long-term benefits of intensive therapy that are observed long after the end of clinical trials and trial interventions in chronic diseases such as diabetes, hyperlipidaemia and hypertension. It emphasizes the importance of intensive treatment to prevent long-term complications and mortality. In chronic kidney disease (CKD), the legacy effect is evident in various studies. Long-term nephroprotection in diabetes is well documented in major studies in the early stages of diabetes, such as Diabetes Control and Complications Trial-Epidemiology of Diabetes Interventions and Complications (DCCT-EDIC), UK Prospective Diabetes Study (UKPDS) and Intensified Multifactorial Intervention in Patients with Type 2 Diabetes and Microalbuminuria (STENO-2). These studies highlight the importance of intensive glycaemic control in reducing microvascular complications, including nephropathy, in patients with recently diagnosed type 1 and type 2 diabetes. However, the legacy effect is less evident in patients with long-term, established diabetes. In chronic glomerulonephritis, studies on immunoglobulin A nephropathy showed that early immunosuppressive treatment could have long-term beneficial effects on kidney function in children and adults with CKD. The Frequent Hemodialysis (FH) and the EXerCise Introduction To Enhance Performance in Dialysis (EXCITE) trials indicated that frequent haemodialysis and a personalized walking exercise program could improve clinical outcomes and reduce the long-term risk of death and hospitalization. The legacy effect concept underscores the importance of intensive intervention in chronic diseases, including CKD. This concept has significant implications for public health and warrants in-depth basic and clinical research to be better understood and exploited in clinical practice. However, its limitations should be considered when interpreting long-term observational data collected after a clinical trial. Appropriate study designs are necessary to investigate an unbiased legacy effect.
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad186
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