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  1. Book ; Online: J.R.R. Tolkien

    Hunt, Peter

    (New Casebooks)

    2013  

    Abstract: This edited collection of brand new essays examines The Hobbit and The Lord of the Rings in the light of children's literature theory and approaches. Exploring issues such as gender, language, narrative, and ecocriticism, the volume also places Tolkien's ...

    Series title New Casebooks
    Abstract This edited collection of brand new essays examines The Hobbit and The Lord of the Rings in the light of children's literature theory and approaches. Exploring issues such as gender, language, narrative, and ecocriticism, the volume also places Tolkien's most popular works in the context of a range of visual media including the film adaptations
    Language English
    Size Online-Ressource (200 p)
    Publisher Palgrave Macmillan
    Publishing place Basingstoke
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781137263995 ; 1137263997
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Re: Mortality after Bladder Augmentation in Children with Spina Bifida: K. M. Szymanski, R. Misseri, B. Whittam, C. M. Adams, J. Kirkegaard, S. King, M. Kaefer, R. C. Rink and M. P. Cain J Urol 2015; 193: 643-648.

    Poulton, Alison / Oakeshott, Pippa / Hunt, Gillian M

    The Journal of urology

    2015  Volume 194, Issue 4, Page(s) 1169–70; discussion 1170–1

    MeSH term(s) Female ; Humans ; Male ; Spinal Dysraphism/mortality ; Urinary Bladder/surgery ; Urinary Bladder, Neurogenic/mortality ; Urinary Bladder, Neurogenic/surgery
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2015.04.089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Call for a Mass Convention of the Dentists.

    Taft, J / Hunt, R Finley / Winder, R B

    The Independent practitioner

    2023  Volume 1, Issue 7, Page(s) 361–362

    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Editorial
    ISSN 1069-0433
    ISSN 1069-0433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Rabies postexposure prophylaxis protocol option for unvaccinated domestic animals, Texas: 2010-2019.

    Wilson, Pamela J / Hunt, Patrick R / Fonken, Eric P

    Journal of the American Veterinary Medical Association

    2024  Volume 262, Issue 5, Page(s) 627–634

    Abstract: Objective: To assess data on rabies postexposure prophylaxis (PEP) in domestic animals following Texas' protocol and to describe preexposure and postexposure vaccination failures from 2010 through 2019.: Animals: 1,218 unvaccinated animals that ... ...

    Abstract Objective: To assess data on rabies postexposure prophylaxis (PEP) in domestic animals following Texas' protocol and to describe preexposure and postexposure vaccination failures from 2010 through 2019.
    Animals: 1,218 unvaccinated animals that received PEP, 925 unvaccinated animals that were euthanatized instead of receiving PEP, and 3 preexposure vaccinated dogs that developed rabies.
    Methods: Zoonotic incident reports from 2010 through 2019 were reviewed for information regarding animals with no known rabies vaccination that received PEP or were euthanatized in accordance with state protocol after exposure to a laboratory-confirmed rabid animal; reports were also reviewed for any preexposure and postexposure vaccination failures. The state-required PEP protocol was to immediately vaccinate the animal against rabies, confine the animal for 90 days, and administer booster vaccines during the third and eighth weeks of the confinement period.
    Results: From 2010 through 2019, 1,218 exposed animals received PEP; 99.8% did not develop rabies. Three failures were recorded, all in animals < 12 weeks of age when PEP was initiated. Additionally, 925 exposed animals were euthanatized instead of receiving PEP. One true preexposure vaccination failure was recorded.
    Clinical relevance: The Texas PEP protocol was used during the 10-year period. Results indicated that this protocol is a viable option for unvaccinated domestic animals exposed to rabies. Alternative protocols warrant additional consideration.
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.23.11.0625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 423: Show issues Location:
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  5. Book ; Online: Advances in Genomics and Epigenomics of Social Insects

    Gadau, Juergen R. / Hunt, Greg J.

    2017  

    Abstract: Social insects are among the most successful and ecologically important animals on earth. The lifestyle of these insects has fascinated humans since prehistoric times. These species evolved a caste of workers that in most cases have no progeny. Some ... ...

    Abstract Social insects are among the most successful and ecologically important animals on earth. The lifestyle of these insects has fascinated humans since prehistoric times. These species evolved a caste of workers that in most cases have no progeny. Some social insects have worker sub-castes that are morphologically specialized for discrete tasks. The organization of the social insect colony has been compared to the metazoan body. Males in the order Hymenoptera (bees, ants and wasps) are haploid, a situation which results in higher relatedness between female siblings. Sociality evolved many times within the Hymenoptera, perhaps spurred in part by increased relatedness that increases inclusive fitness benefits to workers cooperating to raise their sisters and brothers rather than reproducing themselves. But epigenetic processes may also have contributed to the evolution of sociality. The Hymenoptera provide opportunities for comparative study of species ranging from solitary to highly social. A more ancient clade of social insects, the termites (infraorder Isoptera) provide an opportunity to study alternative mechanisms of caste determination and lifestyles that are aided by an array of endosymbionts. This research topic explores the use of genome sequence data and genomic techniques to help us explore how sociality evolved in insects, how epigenetic processes enable phenotypic plasticity, and the mechanisms behind whether a female will become a queen or a worker
    Keywords Genetics ; Science (General)
    Size 1 electronic resource (155 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020095003
    ISBN 9782889450800 ; 2889450805
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Targeting inflammation in traumatic injury: entering a new era.

    Billiar, Timothy R / Hunt, Beverley J / Bailly, Sebastien

    Intensive care medicine

    2023  Volume 49, Issue 8, Page(s) 977–978

    MeSH term(s) Humans ; Brain Injuries, Traumatic ; Brain Injuries ; Inflammation
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-023-07152-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 1089: Show issues Location:
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  7. Article ; Online: Advances and current research in primary thromboprophylaxis to prevent hospital-associated venous thromboembolism.

    Roberts, Lara N / Arya, Roopen / Hunt, Beverley J

    British journal of haematology

    2024  

    Abstract: Hospital-associated venous thromboembolism (VTE) is defined as any case of VTE occurring during hospital admission and for up to 90 days post discharge. It accounts for over 50% of all cases of VTE internationally; indeed, there are an estimated 10 ... ...

    Abstract Hospital-associated venous thromboembolism (VTE) is defined as any case of VTE occurring during hospital admission and for up to 90 days post discharge. It accounts for over 50% of all cases of VTE internationally; indeed, there are an estimated 10 million cases of hospital-associated VTE annually. Over the last decade, there has been increasing interest in improving VTE risk assessment and thromboprophylaxis. This review summarises all the recent and ongoing major research studies and future challenges in the different areas, including medical, surgical and obstetric patients, as well as special areas such as lower limb immobilisation. We include sections on both pharmacological and mechanical thromboprophylaxis.
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.19424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Integration of Augmented Reality Into Glioma Resection Surgery: A Case Report.

    Hunt, Rachel / Scarpace, Lisa / Rock, Jack

    Cureus

    2024  Volume 16, Issue 2, Page(s) e53573

    Abstract: Augmented reality (AR) is an exciting technology that has garnered considerable attention in the field of neurosurgery. Despite this, clinical use of this technology is still in its infancy. An area of great potential for this technology is the ability ... ...

    Abstract Augmented reality (AR) is an exciting technology that has garnered considerable attention in the field of neurosurgery. Despite this, clinical use of this technology is still in its infancy. An area of great potential for this technology is the ability to display 3D anatomy overlaid with the patient to assist with presurgical and intraoperative decision-making. A 39-year-old woman presented with headaches and was experiencing what was described as a whooshing sound. MRI revealed the presence of a large left frontal mass involving the genu of the corpus callosum, with heterogeneous enhancement and central hemorrhagic necrosis, confirmed to be a glioma. She underwent a craniotomy with intraoperative MRI for resection. An augmented reality system was used to superimpose 3D holographic anatomy onto the patient's head for surgical planning. This report highlights a new AR technology and its immediate application to cranial neurosurgery. It is critical to document new uses of this technology as the field continues to integrate AR as well as other next-generation technologies into practice.
    Language English
    Publishing date 2024-02-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Daily patterns in parasite processes: diel variation in fish louse transcriptomes.

    Hunt, R / Cable, J / Ellison, A

    International journal for parasitology

    2022  Volume 52, Issue 8, Page(s) 509–518

    Abstract: Parasites, similar to all other organisms, time themselves to environmental cues using a molecular clock to generate and maintain rhythms. Chronotherapeutic (timed treatment) techniques based on such rhythms offer great potential for improving control of ...

    Abstract Parasites, similar to all other organisms, time themselves to environmental cues using a molecular clock to generate and maintain rhythms. Chronotherapeutic (timed treatment) techniques based on such rhythms offer great potential for improving control of chronic, problematic parasites. Fish lice are a key disease threat in aquaculture, with current control insufficient. Assessing the rhythmicity of fish lice transcriptomes offers not only insight into the viability of chronotherapy, but the opportunity to identify new drug targets. Here, for the first known time in any crustacean parasite, diel changes in gene transcription are examined, revealing that approximately half of the Argulus foliaceus annotated transcriptome displays significant daily rhythmicity. We identified rhythmically transcribed putative clock genes including core clock/cycle and period/timeless pairs, alongside rhythms in feeding-associated genes and processes involving immune response, as well as fish louse drug targets. A substantial number of gene pathways showed peak transcription in hours immediately preceding onset of light, potentially in anticipation of peak host anti-parasite responses or in preparation for increased feeding activity. Genes related to immune haemocyte activity and chitin development were more highly transcribed 4 h post light onset, although inflammatory gene transcription was highest during dark periods. Our study provides an important resource for application of chronotherapy in fish lice; timed application could increase efficacy and/or reduce dose requirement, improving the current landscape of drug resistance and fish health while reducing the economic cost of infection.
    MeSH term(s) Animals ; Aquaculture ; Arguloida/genetics ; Fish Diseases/parasitology ; Parasites/genetics ; Phthiraptera/genetics ; Transcriptome
    Language English
    Publishing date 2022-05-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120518-3
    ISSN 1879-0135 ; 0020-7519
    ISSN (online) 1879-0135
    ISSN 0020-7519
    DOI 10.1016/j.ijpara.2022.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 789: Show issues Location:
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  10. Article ; Online: Intra- and interindividual reliability of muscle pain induced by an intramuscular injection of hypertonic saline injection into the quadriceps.

    Smith, Samuel A / Norbury, Ryan / Hunt, Adam J / Mauger, Alexis R

    European journal of pain (London, England)

    2023  Volume 27, Issue 10, Page(s) 1216–1225

    Abstract: Background: Intramuscular injections of hypertonic saline are commonly used to induce experimental muscle pain, but reliability data on this technique are lacking. This study investigated the intra- and interindividual reliability of pain measures from ... ...

    Abstract Background: Intramuscular injections of hypertonic saline are commonly used to induce experimental muscle pain, but reliability data on this technique are lacking. This study investigated the intra- and interindividual reliability of pain measures from a hypertonic saline injection into the vastus lateralis.
    Methods: Fourteen healthy participants (6 female) attended three laboratory visits where they received an intramuscular injection of 1 mL hypertonic saline into the vastus lateralis. Changes in pain intensity were recorded on an electronic visual analogue scale, and pain quality was assessed after pain had resolved. Reliability was assessed with the coefficient of variation (CV), minimum detectable change (MDC) and intraclass correlation coefficient (ICC) with 95% CIs.
    Results: Mean pain intensity displayed high levels of intraindividual variability (CV = 16.3 [10.5-22.0]%) and 'poor' to 'very good' relative reliability (ICC = 0.71 [0.45-0.88]) but had a MDC of 11 [8-16] au (out of 100). Peak pain intensity exhibited high levels of intraindividual variability (CV = 14.8 [8.8-20.8]%) with 'moderate' to 'excellent' levels of relative reliability (ICC = 0.81 [0.62-0.92]), whereas the MDC was 18 [14-26] au. Measures of pain quality exhibited good reliability. Interindividual variability in pain measures was high (CV > 37%).
    Conclusions: Intramuscular injections of 1 mL of hypertonic saline into the vastus lateralis display substantial levels of interindividual variability, but MDC is below the clinically important changes in pain. This model of experimental pain is suitable for studies involving repeated exposures.
    Significance: Many pain research studies have performed intramuscular injections of hypertonic saline to investigate responses to muscle pain. However, the reliability of this technique is not well established. We examined the pain response over three repeated sessions of a hypertonic saline injection. The pain induced by hypertonic saline has considerable interindividual variability but has largely acceptable intraindividual reliability. Therefore, the injections of hypertonic saline to induce muscle pain are a reliable model of experimental muscle pain.
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1390424-3
    ISSN 1532-2149 ; 1090-3801
    ISSN (online) 1532-2149
    ISSN 1090-3801
    DOI 10.1002/ejp.2151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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