LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 394

Search options

  1. Article ; Online: Cancer Metabolism Historical Perspectives: A Chronicle of Controversies and Consensus.

    Dang, Chi V

    Cold Spring Harbor perspectives in medicine

    2023  

    Abstract: A century ago, Otto Warburg's work sparked the field of cancer metabolism, which has since taken a tortuous path. As evidence accumulated over the decades, consensus views of causes of cancer emerged, whereby genetic and epigenetic oncogenic drivers ... ...

    Abstract A century ago, Otto Warburg's work sparked the field of cancer metabolism, which has since taken a tortuous path. As evidence accumulated over the decades, consensus views of causes of cancer emerged, whereby genetic and epigenetic oncogenic drivers promoted immune evasion and induced new blood vessels and neoplastic metabolism to support tumor growth. Neoplastic cells abandon social cues of intercellular cooperation, escape tissue confinement, metastasize, and ultimately kill the host. Herein, key milestones in the study of cancer metabolism are chronicled with an emphasis on carbohydrate metabolism. The field began with a cancer cell-autonomous view that has been refined by a richer understanding of solid cancers as growing, immune-suppressive, complex organs comprising different cell types that are nourished by a variety of nutrients and variable amounts of oxygen through abnormal neovasculatures. Based on foundational historical studies, our current understanding of cancer metabolism offers a hopeful outlook for targeting metabolism to enhance cancer therapy.
    Language English
    Publishing date 2023-08-08
    Publishing country United States
    Document type Journal Article
    ISSN 2157-1422
    ISSN (online) 2157-1422
    DOI 10.1101/cshperspect.a041530
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Time to hit pause on mitochondria-targeting cancer therapies.

    Zhang, Xue / Dang, Chi V

    Nature medicine

    2023  Volume 29, Issue 1, Page(s) 29–30

    MeSH term(s) Humans ; Mitochondria ; Neoplasms/drug therapy
    Language English
    Publishing date 2023-01-16
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-022-02129-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4212: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 39: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Pathways Involved in the Effect of Eflornithine in Neuroblastoma.

    Wolpaw, Adam J / Dang, Chi V

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 42, Issue 1, Page(s) 116–119

    MeSH term(s) Humans ; Eflornithine ; Tretinoin ; Neuroblastoma/drug therapy
    Chemical Substances Eflornithine (ZQN1G5V6SR) ; Tretinoin (5688UTC01R)
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.01783
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 650: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Sex, life, and death in MYC-driven lymphomagenesis.

    Dang, Chi V

    Molecular cell

    2021  Volume 81, Issue 19, Page(s) 3886–3887

    Abstract: Gong et al. (2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently ... ...

    Abstract Gong et al. (2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently induced for disease progression.
    MeSH term(s) DEAD-box RNA Helicases ; Humans ; Lymphoma ; Male
    Chemical Substances DEAD-box RNA Helicases (EC 3.6.4.13)
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2021.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5055: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Essentiality of non-essential amino acids for tumour cells and tumorigenesis.

    Dang, Chi V

    Nature metabolism

    2019  Volume 1, Issue 9, Page(s) 847–848

    Language English
    Publishing date 2019-09-02
    Publishing country Germany
    Document type Journal Article
    ISSN 2522-5812
    ISSN (online) 2522-5812
    DOI 10.1038/s42255-019-0113-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Sex, life, and death in MYC-driven lymphomagenesis

    Dang, Chi V.

    Molecular cell. 2021 Oct. 07, v. 81, no. 19

    2021  

    Abstract: Gong et al. (2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently ... ...

    Abstract Gong et al. (2021) demonstrate that MYC-induced proteotoxic stress could be relieved by inactivating RNA helicase DDX3X for tumor initiation, and in male MYC-driven lymphomas, the homologous helicase DDX3Y, encoded on the Y chromosome, is subsequently induced for disease progression.
    Keywords RNA helicases ; Y chromosome ; death ; disease progression ; lymphoma ; males
    Language English
    Dates of publication 2021-1007
    Size p. 3886-3887.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2021.09.009
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 2005/501: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Feeding frenzy for cancer cells.

    Dang, Chi V

    Science (New York, N.Y.)

    2017  Volume 358, Issue 6365, Page(s) 862–863

    MeSH term(s) Ammonia ; Biomass ; Breast Neoplasms ; Glutamate Dehydrogenase ; Humans ; Recycling
    Chemical Substances Ammonia (7664-41-7) ; Glutamate Dehydrogenase (EC 1.4.1.2)
    Language English
    Publishing date 2017-11-16
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.aaq1070
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: c-MYC mRNA tail tale about glutamine control of transcription.

    Dang, Chi V

    The EMBO journal

    2017  Volume 36, Issue 13, Page(s) 1806–1808

    MeSH term(s) Glutamine/genetics ; Humans ; Proto-Oncogene Proteins c-myc/genetics ; RNA, Messenger ; Transcription, Genetic
    Chemical Substances Proto-Oncogene Proteins c-myc ; RNA, Messenger ; Glutamine (0RH81L854J)
    Language English
    Publishing date 2017-05-15
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 586044-1
    ISSN 1460-2075 ; 0261-4189
    ISSN (online) 1460-2075
    ISSN 0261-4189
    DOI 10.15252/embj.201796999
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1808: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 100: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: MUC-king with HIF May Rewire Pyrimidine Biosynthesis and Curb Gemcitabine Resistance in Pancreatic Cancer.

    Dang, Chi V

    Cancer cell

    2017  Volume 32, Issue 1, Page(s) 3–5

    Abstract: In this issue of Cancer Cell, Singh and colleagues report a role for MUC1-induced HIF expression in rewiring ribose synthesis, which drives pyridimine production as a possible resistance mechanism to gemcitabine, adding to complexity and multiple paths ... ...

    Abstract In this issue of Cancer Cell, Singh and colleagues report a role for MUC1-induced HIF expression in rewiring ribose synthesis, which drives pyridimine production as a possible resistance mechanism to gemcitabine, adding to complexity and multiple paths to resistance.
    MeSH term(s) Antimetabolites, Antineoplastic ; Cell Line, Tumor ; Deoxycytidine ; Drug Resistance, Neoplasm/drug effects ; Humans ; Pancreatic Neoplasms ; Pyrimidines
    Chemical Substances Antimetabolites, Antineoplastic ; Pyrimidines ; Deoxycytidine (0W860991D6)
    Language English
    Publishing date 2017--10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2078448-X
    ISSN 1878-3686 ; 1535-6108
    ISSN (online) 1878-3686
    ISSN 1535-6108
    DOI 10.1016/j.ccell.2017.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5650: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 104: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Autophagy: clocking in for the night shift.

    Brooks, Rebekah C / Dang, Chi V

    The EMBO journal

    2019  Volume 38, Issue 12

    MeSH term(s) Autophagy ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ; Nutrients ; Transcription Factors
    Chemical Substances Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ; Transcription Factors
    Language English
    Publishing date 2019-05-27
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 586044-1
    ISSN 1460-2075 ; 0261-4189
    ISSN (online) 1460-2075
    ISSN 0261-4189
    DOI 10.15252/embj.2019102434
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1808: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 100: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top