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  1. Article ; Online: Dr. Michael T. Trese - The global mentor for pediatric retinal diseases.

    Jalali, Subhadra

    Indian journal of ophthalmology

    2021  Volume 69, Issue 8, Page(s) 1986–1987

    MeSH term(s) Child ; Diabetic Retinopathy ; Humans ; Mentors ; Retina ; Retinal Diseases ; Retinal Vessels
    Language English
    Publishing date 2021-07-14
    Publishing country India
    Document type Editorial
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1842_21
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  2. Article: Classification of retinopathy of prematurity: from then till now.

    Agarwal, Komal / Jalali, Subhadra

    Community eye health

    2022  Volume 30, Issue 99, Page(s) S4–S7

    Language English
    Publishing date 2022-05-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1036859-0
    ISSN 0953-6833
    ISSN 0953-6833
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  3. Article ; Online: Clinico-Microbiological Correlation in

    Mitra, Sanchita / Meshram, Bhagyashree / Jalali, Subhadra / Basu, Soumyava

    Seminars in ophthalmology

    2024  Volume 39, Issue 4, Page(s) 294–298

    Abstract: Purpose: To report two rare cases of : Methods: Retrospective analysis of medical and microbiology records.: Results: Both of our cases of : Conclusions: ... ...

    Abstract Purpose: To report two rare cases of
    Methods: Retrospective analysis of medical and microbiology records.
    Results: Both of our cases of
    Conclusions: Salmonella
    MeSH term(s) Adult ; Infant, Newborn ; Humans ; Typhoid Fever/drug therapy ; Retrospective Studies ; Anti-Bacterial Agents/therapeutic use ; Endophthalmitis/diagnosis ; Salmonella ; Eye Infections, Bacterial/microbiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 632820-9
    ISSN 1744-5205 ; 0882-0538
    ISSN (online) 1744-5205
    ISSN 0882-0538
    DOI 10.1080/08820538.2024.2308802
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  4. Article: Counselling and co-opting parents to get best outcomes.

    Jalali, Subhadra / Krishnan, Divya Bala

    Community eye health

    2022  Volume 30, Issue 99, Page(s) S29–S31

    Language English
    Publishing date 2022-05-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1036859-0
    ISSN 0953-6833
    ISSN 0953-6833
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  5. Article ; Online: Combined rhegmatogenous and tractional retinal detachment in a child with incontinentia pigmenti managed by scleral imbrication with scleral buckle.

    Belenje, Akash / Jalali, Subhadra

    BMJ case reports

    2023  Volume 16, Issue 2

    Abstract: We report for the first time a child with incontinentia pigmenti presenting with acute-onset rhegmatogenous retinal detachment in association with pre-existing tractional retinal detachment. Due to the combined nature of this detachment, complex vector ... ...

    Abstract We report for the first time a child with incontinentia pigmenti presenting with acute-onset rhegmatogenous retinal detachment in association with pre-existing tractional retinal detachment. Due to the combined nature of this detachment, complex vector forces acting on the retina makes this a difficult to treat situation. A single surgery of modified scleral imbrication with scleral buckle was effective in reattaching the retina by providing a very high buckle indent to accommodate all the complex vector forces. Commonly used procedure of vitrectomy and silicone oil usage was avoided as that often requires multiple surgeries and may result in variable and unpredictable response.
    MeSH term(s) Humans ; Child ; Retinal Detachment/surgery ; Retinal Detachment/complications ; Incontinentia Pigmenti/complications ; Incontinentia Pigmenti/surgery ; Treatment Outcome ; Scleral Buckling ; Retina ; Vitrectomy/methods ; Retrospective Studies
    Language English
    Publishing date 2023-02-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-253738
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  6. Article: Pulmonary oedema in ophthalmic surgeries under peribulbar anaesthesia: A retrospective analysis.

    Kasanavesi, Ramakrishna Chaitanya / Dave, Vivek Pravin / Jalali, Subhadra / Rao, Rajanarsing

    Indian journal of anaesthesia

    2023  Volume 67, Issue 11, Page(s) 1009–1010

    Language English
    Publishing date 2023-11-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_623_23
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  7. Article ; Online: Understanding the relationship between pachychoroid spectrum disorders and retinitis pigmentosa: A review of the evidence.

    Chavan, Kasturi / Chhablani, Jay / Jalali, Subhadra / Padhy, Srikanta Kumar

    Indian journal of ophthalmology

    2024  

    Abstract: This study aims to investigate the relationship between pachychoroid spectrum disorders and retinitis pigmentosa (RP) or rod-cone dystrophy through a comprehensive literature review. The purpose is to explore the association between these disorders, ... ...

    Abstract This study aims to investigate the relationship between pachychoroid spectrum disorders and retinitis pigmentosa (RP) or rod-cone dystrophy through a comprehensive literature review. The purpose is to explore the association between these disorders, understand their underlying mechanisms, and summarize the existing hypotheses and opinions. A thorough review of the literature was conducted using PubMed, focusing on articles related to central serous chorioretinopathy (CSC), RP, pachychoroid pigment epitheliopathy, pachychoroid neovasculopathy, polypoidal choroidal vasculopathy, focal choroidal excavation, peripapillary pachychoroid neovasculopathy, and peripheral exudative hemorrhagic chorioretinopathy. Relevant studies were selected for a detailed narrative review and analysis. Several studies have reported the coexistence of CSC and RP, indicating a potential association between the two conditions. The dysfunction of the retinal pigment epithelium is proposed as a common factor. Choroidal thinning is observed in RP, but conflicting results exist regarding choroidal thickness (CT). While some studies support choroidal thinning in RP, others suggest preserved or increased thickness. Additionally, cases of pachychoroid neovasculopathy and polypoidal choroidal vasculopathy in RP have been reported, suggesting an overlap between these conditions. The literature suggests conflicting reports on CT changes in RP. Future research should focus on large-scale studies using comprehensive imaging techniques, genetic analysis, and long-term follow-up to uncover the underlying mechanisms and determine the prevalence of pachychoroid spectrum disorders in RP patients.
    Language English
    Publishing date 2024-04-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/IJO.IJO_2909_23
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  8. Article ; Online: Generation of Leber congenital amaurosis, type 12 patient-specific induced pluripotent stem cell line (LVPEIi006-A), harboring a homozygous mutation in RD3.

    Mahato, Sudipta / Maddileti, Savitri / Naik, Milind / Kannabiran, Chitra / Jalali, Subhadra / Mariappan, Indumathi

    Stem cell research

    2024  Volume 77, Page(s) 103380

    Abstract: Leber congenital amaurosis (LCA) is a congenital, early onset, autosomal recessive inherited retinal disease (IRD). This report describes an LCA12 patient-specific iPSC line (LVPEIi006-A), generated by the reprogramming of dermal fibroblasts using ... ...

    Abstract Leber congenital amaurosis (LCA) is a congenital, early onset, autosomal recessive inherited retinal disease (IRD). This report describes an LCA12 patient-specific iPSC line (LVPEIi006-A), generated by the reprogramming of dermal fibroblasts using integration-free episomal plasmids.This disease-specific iPSC model carries a homozygous point mutation in RD3, within the donor splice site at the end of exon 2 (c.296 + 1G > A). The stable line at passage 15 has displayed a normal colony morphology, expressed multiple stemness and pluripotency markers, lost all transgenes, differentiated into cell types of all three germ layers, and maintained a normal karyotype.
    Language English
    Publishing date 2024-03-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2024.103380
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  9. Article ; Online: Flicker retinal vasodilation test using a combination of conventional electroretinogram flicker luminescence and blue wavelength autofluorescence.

    Takkar, Brijesh / Jalali, Subhadra

    Medical hypotheses

    2021  Volume 148, Page(s) 110511

    Abstract: Currently, the only available objective measure of functioning of the retinal neuro-vascular unit (NVU) is the flicker retinal vasodilation test (FRVT). The FRVT measures change in retinal vessel diameter after exposure to flickers of light. ... ...

    Abstract Currently, the only available objective measure of functioning of the retinal neuro-vascular unit (NVU) is the flicker retinal vasodilation test (FRVT). The FRVT measures change in retinal vessel diameter after exposure to flickers of light. Unfortunately, it is dependent on a technically adept machine, which is not readily available. In this hypothesis, we propose utilization of 2 commonly available retinal diagnostic tools, the electroretinogram (ERG) and the confocal scanning laser ophthalmoscopy-based fundus auto fluorescence (cSLO-FAF), for performing the FRVT. While the conventional machine based FRVT was performing the flicker luminescence and retinal imaging simultaneously, our hypothesized protocol is dependent on a rapidly performed 2 staged test, the effects of which need to be elicited in a pilot study. As neuroprotection is becoming a therapeutic reality for diseases like diabetic retinopathy, such adaptations may make research and therapy easier.
    MeSH term(s) Diabetic Retinopathy ; Humans ; Luminescence ; Pilot Projects ; Retina/diagnostic imaging ; Vasodilation
    Language English
    Publishing date 2021-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110511
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  10. Article ; Online: Retinopathy of prematurity in triplets - Indian twin city ROP study report number 12.

    Bhate, Manjushree / Agarwal, Komal / Rani, Padmaja Kumari / Belenje, Akash / Parmeshwarappa, Deepika C / Jalali, Subhadra

    Indian journal of ophthalmology

    2024  

    Abstract: Purpose: To evaluate the incidence and severity of retinopathy of prematurity (ROP) amongst surviving triplets.: Methods: Records of preterm babies born to mothers with triplet pregnancies were retrieved from our Indian twin city ROP study database ... ...

    Abstract Purpose: To evaluate the incidence and severity of retinopathy of prematurity (ROP) amongst surviving triplets.
    Methods: Records of preterm babies born to mothers with triplet pregnancies were retrieved from our Indian twin city ROP study database between 1 Jan 2000 and 31 Dec 2020 and analyzed.
    Results: 253 surviving triplet babies born to 108 mothers were evaluated. 48 out of 108 (44%) mothers received treatment for infertility. Data was available and analyzed for 242 babies (484 eyes). Mean gestational age was 31.76 ± 3.74 weeks (26- 38 weeks). The mean birth weight was 1.44 ± 0.37 kg (0.57-2.76 kg). At the first screening, incomplete vascularization was noted in 67% (131 babies;322 eyes) of which ROP was diagnosed in 14% (28 babies; 56 eyes). Among them, only 18 babies (53%) were the smallest birth weight babies in each of the triplet sets. Treatment with laser or bevacizumab was performed in 14 babies (5.8%), one eye of one baby additionally needed vitreoretinal surgical intervention. Good anatomical outcomes in terms of regression of ROP without sequelae were achieved in all babies.
    Conclusion: The present study reveals low incidence and favorable outcomes of ROP in triplet pregnancies in a large cohort of babies from a middle-income country. Our cohort did not show any difference in the treatment-requiring ROP among the larger or smaller birth weight babies of the same gestational age. In multiple pregnancies, gestational age remains a critical factor for ROP development; however, this does not necessitate modifying screening or treatment criteria in such triplet pregnancies.
    Language English
    Publishing date 2024-04-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/IJO.IJO_1700_23
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