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  1. Article: A real-world disproportionality analysis of mepolizumab based on the FDA adverse event reporting system.

    Li, Huqun / Wang, Chongshu / Deng, Aiping / Guo, Cuilian

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1280490

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1280490
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  2. Article ; Online: Retraction Note: Ergosterol Attenuates Isoproterenol-Induced Myocardial Cardiotoxicity.

    Xie, Qifei / Li, Suiji / Gao, Yun / Jin, Ling / Dai, Cuilian / Song, Juan

    Cardiovascular toxicology

    2023  Volume 23, Issue 5-6, Page(s) 231

    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Retraction of Publication
    ZDB-ID 2036765-X
    ISSN 1559-0259 ; 1530-7905
    ISSN (online) 1559-0259
    ISSN 1530-7905
    DOI 10.1007/s12012-023-09796-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5817: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Enhancement of the thermoelectric properties of Zintl phase SrMg

    Yu, Fang / Meng, Xiang / Li, Lu / Wen, Cuilian

    Dalton transactions (Cambridge, England : 2003)

    2022  Volume 51, Issue 4, Page(s) 1513–1520

    Abstract: Due to their low lattice thermal conductivity and manipulable electronic properties, ... ...

    Abstract Due to their low lattice thermal conductivity and manipulable electronic properties, AB
    Language English
    Publishing date 2022-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d1dt03704h
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  4. Article: Association between HOMA-IR and ovarian sensitivity index in women with PCOS undergoing ART: A retrospective cohort study.

    Li, Yan / Wang, Yiwen / Liu, Hai / Zhang, Shaodi / Zhang, Cuilian

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1117996

    Abstract: Introduction: Insulin resistance (IR) may play a central role in the pathophysiology of polycystic ovary syndrome (PCOS). Controlled ovarian stimulation (COS) in PCOS women in the setting of assisted reproductive technology (ART) is always a challenge ... ...

    Abstract Introduction: Insulin resistance (IR) may play a central role in the pathophysiology of polycystic ovary syndrome (PCOS). Controlled ovarian stimulation (COS) in PCOS women in the setting of assisted reproductive technology (ART) is always a challenge for clinicians. However, it remains unclear whether IR in women with PCOS correlates with reduced ovarian sensitivity to exogenous gonadotropin (Gn). This study aimed to explore the association between homeostasis model assessment of insulin resistance (HOMA-IR) and ovarian sensitivity index (OSI).
    Methods: In this retrospective cohort study, we explored the association between Ln HOMA-IR and Ln OSI based on smoothing splines generated by generalized additive model (GAM). Then the correlation between HOMA-IR and OSI was further tested with a multivariable linear regression model and subgroup analysis.
    Results: 1508 women with PCOS aged 20-39 years undergoing their first oocyte retrieval cycle were included consecutively between 2018 until 2022. We observed a negative association between Ln HOMA-IR and Ln OSI by using smoothing splines. In multivariable linear regression analysis, the inverse association between Ln HOMA-IR and Ln OSI was still found in PCOS women after adjustment for potential confounders (β = -0.18, 95% CI -0.25, -0.11). Compared with patients with the lowest tertile of HOMA-IR, those who had the highest tertile of HOMA-IR had lower OSI values (β = -0.25, 95% CI -0.36, -0.15).
    Discussion: Our study provided evidence for the inverse correlation between IR and the ovarian sensitivity during COS in PCOS women. Herein, we proposed new insights for individualized manipulation in PCOS patients with IR undergoing ART.
    MeSH term(s) Humans ; Female ; Insulin Resistance/physiology ; Polycystic Ovary Syndrome/complications ; Retrospective Studies ; Reproductive Techniques, Assisted
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1117996
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  5. Article ; Online: Molten salt electrolytic synthesis of porous carbon from SiC and its application in supercapacitors.

    Zheng, Kai / Luo, Wenbo / Long, Shaolei / Long, Xiao / Shi, Cuilian / Liu, Pengcheng / Li, Jierui / Li, Wubin

    RSC advances

    2023  Volume 13, Issue 23, Page(s) 15498–15505

    Abstract: Nanoscale porous carbide-derived carbon (CDC) microspheres were successfully ... ...

    Abstract Nanoscale porous carbide-derived carbon (CDC) microspheres were successfully synthesized
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra07870h
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  6. Article ; Online: Analysis of endometrial thickness threshold and optimal thickness interval in cleavage embryo hormone replacement freeze-thawed embryo transfer (HRT-FET).

    Shaodi, Zhang / Qiuyuan, Li / Yisha, Yin / Cuilian, Zhang

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2020  Volume 36, Issue 11, Page(s) 968–972

    Abstract: To investigate the effect of endometrial thickness on the clinical outcome of cleavage embryo HRT-FET on the day of embryo transfer and analyzed the threshold and optimal thickness interval corresponding to ideal clinical pregnancy rate by statistical ... ...

    Abstract To investigate the effect of endometrial thickness on the clinical outcome of cleavage embryo HRT-FET on the day of embryo transfer and analyzed the threshold and optimal thickness interval corresponding to ideal clinical pregnancy rate by statistical method. A total of 5861 HRT-FET cycles with cleavage embryo transferred from January 2013 to December 2017 in the Reproductive Medicine Center of Henan Provincial People's Hospital were studied retrospectively．Fifth-order grouping of endometrial thickness (EMT) on embryo transfer day as a continuous variable by statistical software, they were divided into five subgroups: Q1 (EMT:4.0-7.9 mm), Q2 (EMT: 8.0-8.9 mm), Q3 (EMT: 9.0-9.5 mm), Q4 (EMT: 9. 6-10.9 mm), Q5 (EMT: 11.0-19.0 mm). After adjusting for confounding factors, the clinical pregnancy rate and live birth rate in other groups were higher than Group Q1 significantly (
    MeSH term(s) Adult ; Blastocyst/cytology ; Blastocyst/drug effects ; Cleavage Stage, Ovum/cytology ; Cleavage Stage, Ovum/drug effects ; Cryopreservation ; Drug Administration Schedule ; Embryo Implantation/drug effects ; Embryo Transfer/methods ; Endometrium/drug effects ; Endometrium/pathology ; Female ; Fertilization in Vitro/methods ; Freezing ; Hormone Replacement Therapy/methods ; Humans ; Male ; Organ Size/drug effects ; Ovulation Induction/methods ; Pregnancy ; Pregnancy Outcome ; Pregnancy Rate ; Progesterone/administration & dosage ; Retrospective Studies ; Time Factors ; Treatment Outcome
    Chemical Substances Progesterone (4G7DS2Q64Y)
    Language English
    Publishing date 2020-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.1080/09513590.2020.1742686
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2284: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 608: Show issues

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  7. Article ; Online: The effect of endometrial thickness on pregnancy outcomes of frozen-thawed embryo transfer cycles which underwent hormone replacement therapy.

    Shaodi, Zhang / Qiuyuan, Li / Yisha, Yin / Cuilian, Zhang

    PloS one

    2020  Volume 15, Issue 9, Page(s) e0239120

    Abstract: Objective: To investigate the impact of endometrial thickness on the embryo transfer(ET) day on the clinical pregnancy outcomes of frozen-thawed embryo transfer cycles which have undergone hormone replacement therapy(HRT-FET).: Methods: A total of 10, ...

    Abstract Objective: To investigate the impact of endometrial thickness on the embryo transfer(ET) day on the clinical pregnancy outcomes of frozen-thawed embryo transfer cycles which have undergone hormone replacement therapy(HRT-FET).
    Methods: A total of 10,165 HRT-FET cycles performed between January 2013 to December 2017 in the Reproductive Medicine Center of Henan Provincial People's Hospital were studied retrospectively. All patients were grouped according to their endometrial thickness on the ET day (each group having an increment of 1mm between two neighboring groups). Multivariate regression analysis, curve fitting and threshold effect analysis were performed on all data.
    Results: After adjusting for the age, duration of infertility, body mass index(BMI), infertility type and number and type of embryos transferred, a significant correlation was observed to be between the endometrial thickness and implantation rates (aOR: 1.08; 95% CI: 1.06-1.10, p < 0.0001), clinical pregnancy rate(aOR: 1.10; 95% CI: 1.07-1.14, p < 0.0001)and live birth rate (aOR: 1.09; 95% CI: 1.06-1.12, p < 0.0001). The numerical value of the cut-off point for the endometrial thickness was 8.7 mm. When the endometrial thickness was less than 8.7 mm, with each additional 1 mm of endometrial thickness, the implantation rate increased by 32%, the clinical pregnancy rate increased by 36%, and the live birth rate increased by 45%.
    Conclusions: In the HRT-FET cycles, the optimal live birth rate would be obtained when the endometrial thickness remains within the range of 8.7-14.5 mm. If the endometrium is too thin or too thick, the live birth rate will be reduced.
    MeSH term(s) Adult ; China/epidemiology ; Cryopreservation ; Embryo Implantation/physiology ; Embryo Transfer/methods ; Endometrium/anatomy & histology ; Endometrium/diagnostic imaging ; Endometrium/physiology ; Endosonography ; Female ; Hormone Replacement Therapy ; Humans ; Infertility/therapy ; Live Birth/epidemiology ; Pregnancy ; Pregnancy Rate ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2020-09-24
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0239120
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  8. Article ; Online: A comparative study of genotyping and antimicrobial resistance between carbapenem-resistant

    Jian, Xiaoli / Li, Yunyun / Wang, Haiping / Li, Cuilian / Li, Feng / Li, Jue / Dong, Jing / Du, Tingyi / Jiang, Li

    Frontiers in cellular and infection microbiology

    2024  Volume 14, Page(s) 1298202

    Abstract: Background: Carbapenem-resistant : Methods: Ninety-six CRKP and forty-eight CRAB isolates were collected in Kunming Children's Hospital from 2019 through 2022. These isolates were genotyped using repetitive extragenic palindromic-PCR (REP-PCR). ... ...

    Abstract Background: Carbapenem-resistant
    Methods: Ninety-six CRKP and forty-eight CRAB isolates were collected in Kunming Children's Hospital from 2019 through 2022. These isolates were genotyped using repetitive extragenic palindromic-PCR (REP-PCR). Carbapenemase phenotypic and genetic characterization were investigated using a disk diffusion test and singleplex PCR, respectively. In addition, these characteristics of the two pathogens were compared.
    Results: The rates of CRKP and CRAB ranged from 15.8% to 37.0% at the hospital. Forty-nine and sixteen REP genotypes were identified among the 96 and 48 CRKP and CRAB isolates tested, respectively. The CRKP isolates showed more genetic diversity than the CRAB isolates. Of the 96 CRKP isolates, 69 (72%) produced Class B carbapenemases. However, all 48 CRAB isolates produced Class D carbapenemase or extended-spectrum β-lactamases (ESBL) combined with the downregulation of membrane pore proteins. Furthermore, the carbapenemase genes
    Conclusions: These CRKP isolates exhibited different biological and genetic characteristics with dynamic changes, suggesting widespread communities. Continuous epidemiological surveillance and multicenter research should be carried out to strengthen the prevention and control of infections.
    MeSH term(s) Humans ; Child ; Anti-Bacterial Agents/pharmacology ; Klebsiella pneumoniae ; Acinetobacter baumannii ; Genotype ; Hospitals, Pediatric ; Drug Resistance, Bacterial ; beta-Lactamases/genetics ; beta-Lactamases/metabolism ; Carbapenems/pharmacology ; Carbapenem-Resistant Enterobacteriaceae ; Microbial Sensitivity Tests
    Chemical Substances Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6) ; Carbapenems
    Language English
    Publishing date 2024-03-08
    Publishing country Switzerland
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2024.1298202
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  9. Article ; Online: Enhanced Electrochemical Performance of a Ti-Cr-Doped LiMn

    Luo, Yiyuan / Cui, Zhou / Wu, Changxu / Sa, Baisheng / Wen, Cuilian / Li, Hengyi / Huang, Jianping / Xu, Chao / Xu, Zhengbing

    ACS omega

    2023  Volume 8, Issue 25, Page(s) 22721–22731

    Abstract: Ti, Cr dual-element-doped ... ...

    Abstract Ti, Cr dual-element-doped LiMn
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c01524
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  10. Article: Association of HOMA-IR with Ovarian Sensitivity Index in Women Undergoing IVF/ICSI: A Retrospective Cohort Study.

    Li, Yan / Jiang, Yilin / Zhang, Shaodi / Liu, Hai / Zhang, Cuilian

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2023  Volume 16, Page(s) 309–320

    Abstract: Background: Insulin resistance (IR) may adversely impact the in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) outcomes. However, the association of IR with ovarian sensitivity during controlled ovarian hyperstimulation (COH) ... ...

    Abstract Background: Insulin resistance (IR) may adversely impact the in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) outcomes. However, the association of IR with ovarian sensitivity during controlled ovarian hyperstimulation (COH) remains controversial.
    Purpose: We aimed to explore the association between homeostasis model assessment of insulin resistance (HOMA-IR) and ovarian sensitivity index (OSI).
    Patients and methods: In this retrospective cohort study, 7836 patients aged between 20 and 39 years with good ovarian reserve were included consecutively between June 2018 and May 2022. HOMA-IR was calculated to evaluate the degree of IR and OSI was used to measure ovarian sensitivity. Owing to skewed distribution, HOMA-IR and OSI were log e transformed to Ln HOMA-IR and Ln OSI. Smoothing splines were generated by generalized additive models to explore the correlation between Ln HOMA-IR and Ln OSI. Then, the relationship between Ln HOMA-IR and Ln OSI was tested with multivariable linear regression model after adjustments for the potential confounders.
    Results: We observed negative association between Ln HOMA-IR and Ln OSI after adjustment for potential confounders by using smoothing spline fitting curves in generalized additive model. In the multivariable linear regression model, after full adjustments, each one unit increase in Ln HOMA-IR was related to reduced Ln OSI values (β = -0.12, 95% CI, -0.15, -0.09). As sensitivity analysis, those who had HOMA-IR of quartile 3 (HOMA-IR 2.33-3.43) and quartile 4 (HOMA-IR ≥3.43) had decreases in Ln OSI values (β = -0.07, 95% CI -0.11, -0.03 and β = -0.18, 95% CI -0.22, -0.13, respectively) when compared with patients in the quartile 1 (HOMA-IR <1.63). Furthermore, stratified and interaction analysis showed a strong inverse association of Ln HOMA-IR with Ln OSI in subgroups of PCOS patients and overweight/obese populations (
    Conclusion: HOMA-IR value was negatively associated with the ovarian sensitivity assessed by OSI. Among the PCOS and overweight/obese populations, this inverse relationship may be strong. These findings will increase the understanding of the contribution of IR to the development of decreased ovarian sensitivity within the assisted reproductive technology (ART) setting. It may have implications for optimizing gonadotropin dose manipulation in patients with IR undergoing IVF/ICSI.
    Language English
    Publishing date 2023-02-02
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S399105
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