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Article ; Online: Body Uneasiness, Body Figure Perception, and Body Weight: Factor Structure and Longitudinal Measurement Invariance of a Set of Attitudinal and Perceptual Body Image Assessment Tools in Adolescents.

De Caro, Elide Francesca / Grassi, Michele / Di Blas, Lisa

2023 Volume 31, Issue 2, Page(s) 377–396

Abstract: Body image is a multifaceted construct that includes attitudinal and perceptual components, but its attention has mainly been focused on the facet of body dissatisfaction. The present longitudinal study extended the validation of a multifacet attitudinal ...

Abstract	Body image is a multifaceted construct that includes attitudinal and perceptual components, but its attention has mainly been focused on the facet of body dissatisfaction. The present longitudinal study extended the validation of a multifacet attitudinal questionnaire, the Body Uneasiness Test (BUT), against perceptions of body shape and weight. A convenient sample of adolescents took part in a 2-year unbalanced panel study (5 waves). The participants completed the BUT questionnaire and selected their perceived actual, ideal, and reflected body figures along the Contour Drawing Rating Scale; ideal/actual and ideal/normative body mass index discrepancies were also included. After replicating the expected five-factor structure of the BUT items, results from confirmatory factor analysis revealed that the five BUT scales loaded on an attitudinal dimension, whereas the perceived body figures and the discrepancy indices were on a perceptive domain. Such a two-domain structure of body image measures showed gender and seasonal (1-year) measurement invariance, whereas longitudinal 6-month and 18-month invariance partially failed. Overall, the present findings support the validity of the Body Uneasiness Test in adolescence, further demonstrating a preliminary multidimensional structure of body image onto which attitudinal and perceptual body image-related measures were projected.
MeSH term(s)	Humans ; Adolescent ; Body Image ; Longitudinal Studies ; Body Mass Index ; Surveys and Questionnaires ; Body Weight ; Reproducibility of Results ; Psychometrics
Language	English
Publishing date	2023-04-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1362144-0
ISSN	1552-3489 ; 1073-1911
ISSN (online)	1552-3489
ISSN	1073-1911
DOI	10.1177/10731911231162355
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Article: Circadian Variation of Peripheral Blood Cells in Horses Maintained in Different Environmental and Management Conditions.

Aragona, Francesca / Arfuso, Francesca / Fazio, Francesco / De Caro, Salvatore / Giudice, Elisabetta / Monteverde, Vincenzo / Piccione, Giuseppe / Giannetto, Claudia

Animals : an open access journal from MDPI

2023 Volume 13, Issue 11

Abstract: The aim of our study was to analyze circadian rhythm of the hematological profile of horses housed in a loose box and paddock during the different seasons (spring, summer, autumn, and winter). Blood samples were performed every 4 h for 48 consecutive ... ...

Abstract	The aim of our study was to analyze circadian rhythm of the hematological profile of horses housed in a loose box and paddock during the different seasons (spring, summer, autumn, and winter). Blood samples were performed every 4 h for 48 consecutive hours. Red blood cells (RBCs), hemoglobin (HGB), hematocrit (HCT), white blood cells (WBCs), platelets (PLTs), and leukocyte subpopulations (neutrophils, basophils, eosinophils, lymphocytes, and monocytes) were analyzed, and, at the same time, environmental conditions were recorded. A statistically significant effect of housing conditions (
Language	English
Publishing date	2023-06-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13111865
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Article ; Online: Meniscal transplantation in the football player

Francesca de Caro / Jonas Grammens / Peter Verdonk

Journal of Cartilage & Joint Preservation, Vol 2, Iss 2, Pp 100064- (2022)

2022

Abstract: Introduction: Sport activity after meniscal allograft transplantation (MAT) still represents a controversial topic even among knee experts. The major discordance between the authors is whether patients are able to return to pre-injury levels of sports ... ...

Abstract	Introduction: Sport activity after meniscal allograft transplantation (MAT) still represents a controversial topic even among knee experts. The major discordance between the authors is whether patients are able to return to pre-injury levels of sports activity, and wether a return to a high impact sport will result in a higher rate of graft failure compared to a low-impact activity. Objectives: The aim of this narrative review is to evaluate the results of MAT in football players. Methods: In this narrative review we report the data of the literature regarding the return to sport after MAT, with a special focus on football players. Results: At the moment, there is still a lack of high-level clinical data to evaluate the long-term results of MAT. Moreover, only few papers specifically evaluate results of meniscal allograft transplantation in football players. Conclusions: The main finding of this narrative review is that the results of MAT in young active patients are good indeed, with a high number of patients going back to their previous level of sport activity. But this requires a long period of rehabilitation and consequently a long period of stop from the official training. Age is considered a bad prognostic factor, with worse results as age increases. Treatment choice must be discussed by the surgeon and patients together, thus the surgeons must also take in consideration that professional athletes have a high motivation to go back to sports. Shared rehabilitation protocols could help to standardize the return to sport of these active patients.
Keywords	Meniscal allograft transplantation ; Return to sport ; Knee injuries ; Meniscus ; Footbal ; Diseases of the musculoskeletal system ; RC925-935 ; Other systems of medicine ; RZ201-999 ; Sports medicine ; RC1200-1245
Subject code	796
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Diurnal variation in rectal and cutaneous temperatures of horses housed under different management conditions.

Giannetto, Claudia / Aragona, Francesca / Arfuso, Francesca / Piccione, Giuseppe / De Caro, Salvatore / Fazio, Francesco

International journal of biometeorology

2022 Volume 66, Issue 8, Page(s) 1601–1611

Abstract: Thermoregulation is an important mechanism to ensure thermal homeostasis. In horses, different housing conditions could influence this mechanism by exposing animals to different microclimates. The circadian rhythm of body temperature is well known. For ... ...

Abstract	Thermoregulation is an important mechanism to ensure thermal homeostasis. In horses, different housing conditions could influence this mechanism by exposing animals to different microclimates. The circadian rhythm of body temperature is well known. For this reason, we wanted to investigate the daily rhythm of cutaneous (jugular, shoulder, inner thigh and croup) temperature in comparison to rectal temperature in athletic horses kept under two different housing conditions. Ten clinically healthy Italian Saddle horses were divided into two equal groups: the first group was housed in individual boxes, and the second group was kept in paddocks. In all horses, rectal and cutaneous temperature measurements were performed every 4 h for 48 consecutive hours during different seasons (spring, summer, autumn and winter), respectively, by means of digital and infrared thermometers. Ambient temperature, relative humidity and ventilation were recorded simultaneously. A general linear model (GLM) was applied to the recorded temperature values displaying a significant effect of season, time of day, site of recording and housing condition (p < 0.001). No statistical differences were found between the two days of monitoring (p = 0.49). A trigonometric statistical model (single cosinor method) was applied to investigate the circadian rhythm of rectal and cutaneous temperatures in the two different groups. Our results showed circadian rhythmicity of rectal temperature during all seasons and in both groups. Cutaneous temperature shows daily rhythmicity that was different in the various regions and was influenced by housing conditions and seasons. Application of GLM also showed a statistically significant effect of season and site of recording (p < 0.0001) on all circadian parameters and of management condition on amplitude and robustness (p < 0.0001). No statistical differences between the two days of monitoring were observed (p = 0.68). These findings are probably due to the animals' thermoregulatory mechanisms ensuring heat exchange between the body and the environment, and that was influenced by the microclimate. In particular, the microclimate influenced the thermodispersion disrupting the daily rhythmicity of some body regions, in horses kept in boxes. Only the temperate climatic conditions observed in summer guarantee the expression of the daily rhythmicity of all body surfaces in both management conditions. These results contribute to the knowledge of the mechanisms of homeostasis and control of body temperature in the athletic horse kept in different housing conditions, with a chronophysiological interpretation that completes the proper management of thermal well-being in horses.
MeSH term(s)	Animals ; Body Temperature ; Circadian Rhythm/physiology ; Horses ; Seasons ; Skin Temperature ; Temperature
Language	English
Publishing date	2022-05-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	280324-0
ISSN	1432-1254 ; 0020-7128
ISSN (online)	1432-1254
ISSN	0020-7128
DOI	10.1007/s00484-022-02304-3
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Article ; Online: Zooming into Gut Dysbiosis in Parkinson's Disease: New Insights from Functional Mapping.

Turco, Luigia / Opallo, Nicola / Buommino, Elisabetta / De Caro, Carmen / Pirozzi, Claudio / Mattace Raso, Giuseppina / Lembo, Francesca / Coretti, Lorena

International journal of molecular sciences

2023 Volume 24, Issue 11

Abstract: Gut dysbiosis has been involved in the pathogenesis and progression of Parkinson's disease (PD), but the mechanisms through which gut microbiota (GM) exerts its influences deserve further study. Recently, we proposed a two-hit mouse model of PD in which ... ...

Abstract	Gut dysbiosis has been involved in the pathogenesis and progression of Parkinson's disease (PD), but the mechanisms through which gut microbiota (GM) exerts its influences deserve further study. Recently, we proposed a two-hit mouse model of PD in which ceftriaxone (CFX)-induced dysbiosis amplifies the neurodegenerative phenotype generated by striatal 6-hydroxydopamine (6-OHDA) injection in mice. Low GM diversity and the depletion of key gut colonizers and butyrate producers were the main signatures of GM alteration in this model. Here, we used the phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt2) to unravel candidate pathways of cell-to-cell communication associated with dual-hit mice and potentially involved in PD progression. We focused our analysis on short-chain fatty acids (SCFAs) metabolism and quorum sensing (QS) signaling. Based on linear discriminant analysis, combined with the effect size results, we found increased functions linked to pyruvate utilization and a depletion of acetate and butyrate production in 6-OHDA+CFX mice. The specific arrangement of QS signaling as a possible result of the disrupted GM structure was also observed. With this exploratory study, we suggested a scenario in which SCFAs metabolism and QS signaling might represent the effectors of gut dysbiosis potentially involved in the designation of the functional outcomes that contribute to the exacerbation of the neurodegenerative phenotype in the dual-hit animal model of PD.
MeSH term(s)	Mice ; Animals ; Parkinson Disease/metabolism ; Dysbiosis/metabolism ; Phylogeny ; Oxidopamine ; Butyrates
Chemical Substances	Oxidopamine (8HW4YBZ748) ; Butyrates
Language	English
Publishing date	2023-06-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24119777
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Article ; Online: Returning to orthopaedic business as usual after COVID-19: strategies and options.

de Caro, Francesca / Hirschmann, Thomas Michael / Verdonk, Peter

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

2020 Volume 28, Issue 6, Page(s) 1699–1704

Abstract: Purpose: The aim of this manuscript is to review the available strategies in the international literature to efficiently and safely return to both normal orthopaedic surgical activities and to normal outpatient clinical activities in the aftermath of a ... ...

Abstract	Purpose: The aim of this manuscript is to review the available strategies in the international literature to efficiently and safely return to both normal orthopaedic surgical activities and to normal outpatient clinical activities in the aftermath of a large epidemic or pandemic. This information would be beneficial to adequately reorganize outpatient clinics and hospitals to provide the highest possible level of orthopaedic care to our patients in a safe and efficient manner. Methods: A literature search was performed for relevant research articles. In addition, the World Health Organisation (WHO), the US Centers for Disease Control (CDC), American Association of Orthopaedic Surgeons (AAOS), the EU CDC and other government health agency websites were searched for any relevant information. In particular, interest was paid to strategies and advise on managing the orthopaedic patient flow during outpatient clinics as well as surgical procedures including the necessary safety measures, while still providing a high-quality patient experience. The obtained information is provided as a narrative review. Results: There was not any specific literature concerning the organization of an outpatient clinic and surgical activities and the particular challenges in dealing with a high-volume practice, in the afterwave of a pandemic. Conclusion: As the COVID-19 crisis has abruptly halted most of the orthopaedic activities both in the outpatient clinic and the operating room, a progressive start-up scenario needs to be planned. The exact timing largely depends on factors outside of our control. After restrictions will be lifted, clinical and surgical volume will progressively increase. This paper offers key points and possible strategies to provide the highest level of safety to both the orthopaedic patient and the orthopaedic team including administrative staff and nurses, during the start-up phase. Level of evidence: Review, Level V.
MeSH term(s)	Ambulatory Care Facilities/organization & administration ; Ambulatory Care Facilities/standards ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Disease Transmission, Infectious/prevention & control ; Efficiency, Organizational ; Humans ; Infection Control/standards ; Orthopedic Procedures/standards ; Orthopedics/organization & administration ; Orthopedics/standards ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Practice Guidelines as Topic ; SARS-CoV-2 ; Safety
Keywords	covid19
Language	English
Publishing date	2020-04-27
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1159064-6
ISSN	1433-7347 ; 0942-2056
ISSN (online)	1433-7347
ISSN	0942-2056
DOI	10.1007/s00167-020-06031-3
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Article ; Online: Circadian Variation of Peripheral Blood Cells in Horses Maintained in Different Environmental and Management Conditions

Francesca Aragona / Francesca Arfuso / Francesco Fazio / Salvatore De Caro / Elisabetta Giudice / Vincenzo Monteverde / Giuseppe Piccione / Claudia Giannetto

Animals, Vol 13, Iss 1865, p

2023 Volume 1865

Abstract	The aim of our study was to analyze circadian rhythm of the hematological profile of horses housed in a loose box and paddock during the different seasons (spring, summer, autumn, and winter). Blood samples were performed every 4 h for 48 consecutive hours. Red blood cells (RBCs), hemoglobin (HGB), hematocrit (HCT), white blood cells (WBCs), platelets (PLTs), and leukocyte subpopulations (neutrophils, basophils, eosinophils, lymphocytes, and monocytes) were analyzed, and, at the same time, environmental conditions were recorded. A statistically significant effect of housing conditions ( p < 0.0001) was observed on all hematological values except for WBC during winter and for neutrophils ( p < 0.0001) during spring and autumn. A statistically significant effect of season ( p < 0.0001) was found for RBC, HCT, and PLT and for all leukocyte cells ( p < 0.0001) except for basophils. The single Cosinor method revealed a daily rhythm of hematological parameters during spring in both groups, and a daily rhythm for lymphocytes and neutrophils was observed during spring and summer in horses kept in a loose box and during winter in horses housed in a paddock. Our results revealed that the response of the immune system is regulated by circadian physiology. Knowledge of the periodic temporal structure of mammals should be considered when evaluating animals’ adaptation to temporizations imposed by the environment.
Keywords	horse ; circadian physiology ; season ; CBC ; environmental changes ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
Subject code	630
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article: Monkeypox Infection 2022: An Updated Narrative Review Focusing on the Neonatal and Pediatric Population.

Gaeta, Francesca / De Caro, Francesco / Franci, Gianluigi / Pagliano, Pasquale / Vajro, Pietro / Mandato, Claudia

Children (Basel, Switzerland)

2022 Volume 9, Issue 12

Abstract: Monkeypox disease has been endemic in sub-Saharan Africa for decades, attracting remarkable attention only i23n 2022 through the occurrence of a multi-country outbreak. The latter has raised serious public health concerns and is considered a public ... ...

Abstract	Monkeypox disease has been endemic in sub-Saharan Africa for decades, attracting remarkable attention only i23n 2022 through the occurrence of a multi-country outbreak. The latter has raised serious public health concerns and is considered a public health emergency by the World Health Organization. Although the disease is usually self-limiting, it can cause severe illness in individuals with compromised immune systems, in children, and/or the pregnant woman-fetus dyad. Patients generally present with fever, lymphadenopathy, and a vesicular rash suggestive of mild smallpox. Serious eye, lung and brain complications, and sepsis can occur. However, cases with subtler clinical presentations have been reported in the recent outbreak. A supportive care system is usually sufficient; otherwise, treatment options are needed in patients who are immunocompromised or with comorbidities. A replication-deficient modified and a live infectious vaccinia virus vaccine can be used both before and after exposure. Due to the persistent spread of monkeypox, it is necessary to focus on the pediatric population, pregnant women, and newborns, who represent fragile contagion groups. Here we assess and summarize the available up-to-date information, focusing on available therapeutic options, with insights into social and school management, breastfeeding, and prevention that will be useful for the scientific community and in particular neonatal and pediatric health professionals.
Language	English
Publishing date	2022-11-26
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children9121832
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Article ; Online: Returning to orthopaedic business as usual after COVID-19

de Caro, Francesca / Hirschmann, Thomas Michael / Verdonk, Peter

Knee Surgery, Sports Traumatology, Arthroscopy

strategies and options

2020 Volume 28, Issue 6, Page(s) 1699–1704

Keywords	Surgery ; Orthopedics and Sports Medicine ; covid19
Language	English
Publisher	Springer Science and Business Media LLC
Publishing country	us
Document type	Article ; Online
ZDB-ID	1159064-6
ISSN	1433-7347 ; 0942-2056
ISSN (online)	1433-7347
ISSN	0942-2056
DOI	10.1007/s00167-020-06031-3
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Diurnal variation in rectal and cutaneous temperatures of horses housed under different management conditions

Giannetto, Claudia / Aragona, Francesca / Arfuso, Francesca / Piccione, Giuseppe / De Caro, Salvatore / Fazio, Francesco

International journal of biometeorology. 2022 Aug., v. 66, no. 8

2022

Abstract	Thermoregulation is an important mechanism to ensure thermal homeostasis. In horses, different housing conditions could influence this mechanism by exposing animals to different microclimates. The circadian rhythm of body temperature is well known. For this reason, we wanted to investigate the daily rhythm of cutaneous (jugular, shoulder, inner thigh and croup) temperature in comparison to rectal temperature in athletic horses kept under two different housing conditions. Ten clinically healthy Italian Saddle horses were divided into two equal groups: the first group was housed in individual boxes, and the second group was kept in paddocks. In all horses, rectal and cutaneous temperature measurements were performed every 4 h for 48 consecutive hours during different seasons (spring, summer, autumn and winter), respectively, by means of digital and infrared thermometers. Ambient temperature, relative humidity and ventilation were recorded simultaneously. A general linear model (GLM) was applied to the recorded temperature values displaying a significant effect of season, time of day, site of recording and housing condition (p < 0.001). No statistical differences were found between the two days of monitoring (p = 0.49). A trigonometric statistical model (single cosinor method) was applied to investigate the circadian rhythm of rectal and cutaneous temperatures in the two different groups. Our results showed circadian rhythmicity of rectal temperature during all seasons and in both groups. Cutaneous temperature shows daily rhythmicity that was different in the various regions and was influenced by housing conditions and seasons. Application of GLM also showed a statistically significant effect of season and site of recording (p < 0.0001) on all circadian parameters and of management condition on amplitude and robustness (p < 0.0001). No statistical differences between the two days of monitoring were observed (p = 0.68). These findings are probably due to the animals’ thermoregulatory mechanisms ensuring heat exchange between the body and the environment, and that was influenced by the microclimate. In particular, the microclimate influenced the thermodispersion disrupting the daily rhythmicity of some body regions, in horses kept in boxes. Only the temperate climatic conditions observed in summer guarantee the expression of the daily rhythmicity of all body surfaces in both management conditions. These results contribute to the knowledge of the mechanisms of homeostasis and control of body temperature in the athletic horse kept in different housing conditions, with a chronophysiological interpretation that completes the proper management of thermal well-being in horses.
Keywords	ambient temperature ; autumn ; bioclimatology ; body temperature ; circadian rhythm ; diurnal variation ; heat transfer ; homeostasis ; horses ; linear models ; microclimate ; relative humidity ; spring ; summer ; thermoregulation ; winter
Language	English
Dates of publication	2022-08
Size	p. 1601-1611.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	127361-9
ISSN	0067-8902 ; 0020-7128
ISSN	0067-8902 ; 0020-7128
DOI	10.1007/s00484-022-02304-3
Database	NAL-Catalogue (AGRICOLA)

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