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Article: Giant frontal sinus mucocele mimicked a primary brain tumor: A case report.

Shojaei, Hamidreza / Mollahoseini, Reza / Kargar-Soleimanabad, Saeed

International journal of surgery case reports

2024 Volume 118, Page(s) 109598

Abstract: Introduction: Frontal sinus mucoceles commonly manifest with orbital complications. Intracranial complications, though rare, are significant in the differential diagnosis. Tumefactive and giant mucoceles can resemble intracranial tumors.: Case ... ...

Abstract	Introduction: Frontal sinus mucoceles commonly manifest with orbital complications. Intracranial complications, though rare, are significant in the differential diagnosis. Tumefactive and giant mucoceles can resemble intracranial tumors. Case presentation: We present the case of a 24-year-old male patient who initially presented to our institution after experiencing a single generalized tonic-clonic seizure. Initial imaging revealed large masses in both frontal lobes. Surgical intervention revealed mucoceles originating from the frontal and paranasal sinuses. Discussion: Mucoceles are often misdiagnosed due to the wide variety of symptoms they can present. In particular, the tumefactive type of mucoceles can present brain tumors both clinically and radiologically. Conclusion: Mucoceles can manifest as tumefactive lesions, mimicking intracranial masses, and may present as perplexing neurological conditions.
Language	English
Publishing date	2024-03-31
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2024.109598
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical uses and safety concerns of tyrosine kinase inhibitors with a focus on novel drugs: A narrative review.

Boskabadi, Seyyed Javad / Dashti, Ayat / Karevan, Sara / Kargar-Soleimanabad, Saeed / Salehifar, Ebrahim

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2023 , Page(s) 10781552231174790

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2023-05-12
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552231174790
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Article ; Online: Lovastatin production by Aspergillus terreus in membrane gradostat bioreactor with two-stage feeding strategy

Kargar, Saeed / Mohseny Takloo, Sepide / Jalili, Hasan / NoorMohammedi, Jhamak / Babaei, Alireza / Bizukojc, Marcin

Preparative Biochemistry & Biotechnology. 2023 Mar. 1, v. 53, no. 3 p.247-254

2023

Abstract: Lovastatin is a blood cholesterol-lowering agent and is produced as a secondary metabolite by Aspergillus terreus. Microbial production of this drug is carried out in solid-state or submerged culture, and due to difficulties of controlling the procedure ... ...

Abstract	Lovastatin is a blood cholesterol-lowering agent and is produced as a secondary metabolite by Aspergillus terreus. Microbial production of this drug is carried out in solid-state or submerged culture, and due to difficulties of controlling the procedure parameters in solid-state method, the submerged method is conventional for industrial production. Although the submerged method is widely used, but this method damages the morphology of fungus due to shear stress caused by stirring. Since the morphology of fungus is a key factor in lovastatin production, using a bioreactor that causes the least damage to it, can improve the lovastatin production. In this paper, for the first time, it has been shown that the membrane gradostat bioreactor is suitable for lovastatin production, using A. terreus, due to providing suitable environmental conditions, therefore, it can be implemented as an alternative method for lovastatin production. Furthermore, it was found that implementing two-stage feeding, using different ratios of Carbon to Nitrogen in the culture medium, makes the lovastatin production to be 5 times more than one-stage feeding. Finally, it is shown that adding Zinc and Magnesium at the second stage further increases lovastatin production by 18%.
Keywords	Aspergillus terreus ; bioreactors ; blood ; carbon ; culture media ; fungi ; lovastatin ; magnesium ; nitrogen ; secondary metabolites ; shear stress ; zinc ; gradostat bioreactor ; membrane ; two-stages feeding
Language	English
Dates of publication	2023-0301
Size	p. 247-254.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2022.2076242
Database	NAL-Catalogue (AGRICOLA)

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Article: Spontaneous Hemothorax during pregnancy: A case report.

Zamaniyan, Marzieh / Jafari, Kaveh / Kargar-Soleimanabad, Saeed / Nikzad Jamnani, Alireza

International journal of surgery case reports

2022 Volume 99, Page(s) 107660

Abstract: Introduction and importance: Spontaneous hemothorax is a rare but life-threatening condition, which is the main cause of respiratory distress during pregnancy and after delivery without any evidence of post-traumatic injury.: Case presentation: A 34- ... ...

Abstract	Introduction and importance: Spontaneous hemothorax is a rare but life-threatening condition, which is the main cause of respiratory distress during pregnancy and after delivery without any evidence of post-traumatic injury. Case presentation: A 34-year-old woman, pregnant at 20 weeks, presented in the emergency department complaining of dyspnea accompanied by epigastric pain, with dominance on the left side. Chest X-ray and CT-scan revealed an opacity by displacing heart to the right side. Considering, there was a probability of bleeding from venous arterial malformation. Inappropriate cervical condition two days after the patient appeared thermodynamically stable a cesarean section was performed. Clinical discussion: Pregnancy leads to increasing the size of AVM by rising cardiac output and hypoxia. Patients who are predisposed to PAVM and intend to be pregnant should be evaluated a priori. Conclusion: Although the hemothorax is a rare phenomenon during pregnancy, management of fetus following this critical condition requires multidisciplinary assessment.
Language	English
Publishing date	2022-09-14
Publishing country	Netherlands
Document type	Case Reports
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2022.107660
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: New-onset chronic inflammatory demyelinating polyradiculoneuropathy after COVID-19 infection: a case report.

Abedi Samakoush, Mohammad / Davoodi, Lotfollah / Khademian, Mojtaba / Kargar-Soleimanabad, Saeed / Abedini, Mohammad-Ali

Annals of medicine and surgery (2012)

2023 Volume 85, Issue 10, Page(s) 5031–5034

Abstract: Introduction and importance: SARS-CoV-2 infection, besides respiratory symptoms, as cardinal manifestation, may present with neurological involvement. Immune-mediated polyradiculoneuropathy is one of the important neurological complications manifested ... ...

Abstract	Introduction and importance: SARS-CoV-2 infection, besides respiratory symptoms, as cardinal manifestation, may present with neurological involvement. Immune-mediated polyradiculoneuropathy is one of the important neurological complications manifested by COVID-19 mainly includes Guillain-Barré syndrome (GBS), treatment-related fluctuation of GBS, and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Also, there are several reports of COVID-19 vaccine-related GBS and CIDP. According to possible severe manifestations of neuropathies like respiratory failure, considering these complications for early diagnosis and treatment is very important. Case presentation: The authors presented a 67-year-old woman with severe weakness in upper and lower extremities, the patient was diagnosed as case with CIDP initiated after COVID-19 virus infection and/or vaccination that experienced one relapse in 11 months. In both episodes, treatment with intravenous immunoglobulin started and the patient respond. Clinical discussion: To the best of our knowledge, this is one of the first reported cases with a typical chronic course of CIDP associated with COVID-19 virus infection and/or vaccination. Conclusion: Considering this complication and differentiation between GBS and CIDP, and then initiating maintenance therapy can prevent long-term disability.
Language	English
Publishing date	2023-07-31
Publishing country	England
Document type	Case Reports
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1097/MS9.0000000000000352
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Article ; Online: Alvarado or RIPASA? Which one do you use to diagnose acute appendicitis?: A cross-sectional study.

Heiranizadeh, Naeimeh / Mousavi Beyuki, Seyyed Mohammad Hossein / Kargar, Saeed / Abadiyan, Aryana / Mohammadi, Hamid Reza

Health science reports

2023 Volume 6, Issue 1, Page(s) e1078

Abstract: Background and aims: Acute appendicitis is one of the most common causes of lower abdominal pain, which is considered a general surgical emergency worldwide. The present study aimed to compare the diagnostic value of Raja Isteri Pengiran Anak Saleha ... ...

Abstract	Background and aims: Acute appendicitis is one of the most common causes of lower abdominal pain, which is considered a general surgical emergency worldwide. The present study aimed to compare the diagnostic value of Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) and Alvarado score systems in diagnosing acute appendicitis. Methods: A prospective cross-sectional study was conducted at Shahid Sadoughi and Shahid Rahnemoon Hospitals in Yazd between September 2020 and February 2020. The statistical population consisted of all of the patients referred to the Accident and Emergency department with right iliac fossa (RIF) pain. All patients were scored using Alvarado and RIPASA scoring system. sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were computed by using SPSS statistical software. An receiver operating characteristic curve were plotted. Results: In present study, one hundred suspected patients with appendicitis who underwent appendectomy were evaluated. The mean age of our study population was 25.2 ± 12.1 years, and the gender distribution was 57% males and 43% females. The sensitivity, specificity, PPV and NPV of RIPASA were 86.6%, 66.7%, 92.2%, and 52.2%, respectively. The sensitivity, specificity, PPV and NPV of Alvarado score were 67.1%, 72.2%, 91.7%, 32.5%, respectively. The diagnostic accuracy was 68% for Alvarado score and 83% for RIPASA. The area under the curve for RIPASA (0.87) was more than that for Alvarado score (0.77). Conclusion: The RIPASA score system had higher sensitivity, PPV, NPV, and accuracy than the Alvarado one. It is recommended for the physician and surgeon to evaluate patients with RIF pain using the RIPASA score.
Language	English
Publishing date	2023-01-19
Publishing country	United States
Document type	Journal Article
ISSN	2398-8835
ISSN (online)	2398-8835
DOI	10.1002/hsr2.1078
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Article: Predictive performance of SOFA (Sequential Organ Failure Assessment) and qSOFA (quick Sequential Organ Failure Assessment) for in-hospital mortality in ICU patients with COVID-19 of referral center in the north of Iran a retrospective study.

Nikzad Jamnani, Alireza / Gholipour Baradari, Afshin / Kargar-Soleimanabad, Saeed / Javaheri, Sepehr

Annals of medicine and surgery (2012)

2023 Volume 85, Issue 11, Page(s) 5414–5419

Abstract: Introduction: Patients diagnosed with Coronavirus disease 2019 exhibit varied clinical outcomes, with a reported mortality rate exceeding 30% in those requiring admission to the ICU. The objective of this study was to assess the predictive capacity of ... ...

Abstract	Introduction: Patients diagnosed with Coronavirus disease 2019 exhibit varied clinical outcomes, with a reported mortality rate exceeding 30% in those requiring admission to the ICU. The objective of this study was to assess the predictive capacity of Sequential Organ Failure Assessment (SOFA) and quick Sequential Organ Failure Assessment (qSOFA) scores in determining mortality risk among severe COVID-19 patients. Method and materials: This retrospective study was performed by analyzing the data of patients with COVID-19 who were hospitalized in the ICUs. Data collection of the parameters required to calculate the SOFA and qSOFA Scores were extracted from patient's medical records. All data analysis was performed using SPSS V.25. Significance level considered as Findings: In this study, 258 patients were included. The results showed that the subjects ranged in age from 21 to 98 years with a mean and SD of 62.7±15.6. Of all patients, 127 (49.2%) were female and the rest were male. The mortality rate was 102 (39.5%). The underlying disease of diabetes mellitus with an odds ratio of 1.81 (CI=1.02-3.22) had a significant effect on mortality. In addition, a significant correlation was obtained between admission duration and SOFA score (r=0.147, Conclusion: The findings of present study illustrated that deceased COVID-19 patients admitted to the ICU had higher scores on both SOFA and qSOFA scales than surviving patients. Also, both scales have high sensitivity and specificity for anticipating of mortality in these patients. The underlying diabetes mellitus was associated with an increase in patient mortality.
Language	English
Publishing date	2023-09-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1097/MS9.0000000000001304
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Article: Psychosis due to anxiety related to COVID-19: A case report.

Kargar-Soleimanabad, Saeed / Dehbozorgi, Raziye / Mahdi Mahdavinoor, Seyyed Muhammad

Annals of medicine and surgery (2012)

2022 Volume 78, Page(s) 103795

Abstract: Introduction and importance: Limited information is available regarding various effects of lifestyle changes caused by coronavirus pandemic on human life. On the other hand, if the fear of getting infected by coronavirus is accompanied by other ... ...

Abstract	Introduction and importance: Limited information is available regarding various effects of lifestyle changes caused by coronavirus pandemic on human life. On the other hand, if the fear of getting infected by coronavirus is accompanied by other psychological crises, it can possibly lead to psychosis in people with or without a previous history of mental illness. Case presentation: The patient is a 36-year-old man with no previous history of mental illness who divorced his wife 6 months before the onset of COVID-19 pandemic. The patient developed auditory hallucinations and paranoid thoughts after the outbreak. After diagnosis of psychosis, treatment with injectable haloperidol was started. He was then treated with risperidone for maintenance therapy. On the other hand, for depressive symptoms, the patient was treated with bupropion. One week after starting the treatment, the patient's paranoid thoughts and auditory hallucinations improved. Clinical discussion: Getting infected with coronavirus or being severely afraid of it may cause symptoms of psychosis in those with a history of previous mental disease. There is also evidence that extreme fear of infection with coronavirus can lead to psychosis if accompanied by other psychological crises. Conclusion: It is necessary to pay more attention to the diagnosis and treatment of anxiety caused by COVID-19. Failure to immediately treat the anxiety caused by the fear of infection in this pandemic or other epidemics can lead to more serious problems such as psychosis and create further risks for the individual, family and community.
Language	English
Publishing date	2022-05-16
Publishing country	England
Document type	Case Reports
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1016/j.amsu.2022.103795
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Article ; Online: Lovastatin production by

Kargar, Saeed / Mohseny Takloo, Sepide / Jalili, Hasan / NoorMohammedi, Jhamak / Babaei, Alireza / Bizukojc, Marcin

Preparative biochemistry & biotechnology

2022 Volume 53, Issue 3, Page(s) 247–254

Abstract: Lovastatin is a blood cholesterol-lowering agent and is produced as a secondary metabolite ... ...

Abstract	Lovastatin is a blood cholesterol-lowering agent and is produced as a secondary metabolite by
MeSH term(s)	Lovastatin ; Bioreactors ; Aspergillus/metabolism ; Nitrogen/metabolism
Chemical Substances	Lovastatin (9LHU78OQFD) ; Nitrogen (N762921K75)
Language	English
Publishing date	2022-05-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2022.2076242
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Article ; Online: Clinical Trial of Intraperitoneal Administration of Ketamine Combined with Bupivacaine on Pain Status after Laparoscopic Cholecystectomy

Parvin Ziaei / Saeed Kargar / Mohammad Hossein Dehghan / Farzan Madadizadeh / Hamid Reza Jamshidi

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 30, Iss 11, Pp 6107-

2023 Volume 6117

Abstract: Introduction: One of the most important problems that the patient faces after laparoscopic surgery is pain that is felt in the shoulders, back and abdomen. This study was designed to evaluate the effects of the combination of bupivacaine and ketamine and ...

Abstract	Introduction: One of the most important problems that the patient faces after laparoscopic surgery is pain that is felt in the shoulders, back and abdomen. This study was designed to evaluate the effects of the combination of bupivacaine and ketamine and its intraperitoneal injection on reducing shoulder pain after laparoscopic cholecystectomy. Methods: This was a double-blind randomized study that included 90 patients undergoing elective surgery for laparoscopic cholecystectomy in the age group of 18-65 years and of both sexes. After removal of the gallbladder, 20 cc of solution was injected intraperitoneally at the surgical site. Patients were randomly assigned to three groups receiving 10 cc 0.5% bupivacaine + 0.5cc ketamine, the second group received 10 cc of %0.5 bupivacaine and 10 cc normal saline, the third group (control) received 20 cc of normal saline intraperitoneally. The findings were analyzed using SPSS version 16 software and repeated measurement analysis of variance and Bonferroni's pairwise comparison test. Results: Analysis of variance showed that the mean pain scores were significantly different over time in each group (P<0.001). (P<0.001). Bonferroni paired comparison test showed that the lowest amount of pain was in the first group (p<0.05). Conclusion: According to the results of the present study, intraperitoneal injection of ketamine combined with bupivacaine significantly (p<0.001) reduces pain up to 8 hours after laparoscopic cholecystectomy.
Keywords	laparoscopic cholecystectomy ; shoulder pain ; intraperitoneal ; ketamine ; bupivacaine ; Medicine (General) ; R5-920
Subject code	796 ; 616
Language	Persian
Publishing date	2023-02-01T00:00:00Z
Publisher	Shahid Sadoughi University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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