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  1. Article ; Online: The m

    Yang, Zizhao / Verghese, Michelle / Yang, Seungwon / Shah, Palak / He, Yu-Ying

    Photochemistry and photobiology

    2024  

    Abstract: Ultraviolet B (UVB) radiation represents a major carcinogen for the development of all skin cancer types. Mechanistically, UVB induces damage to DNA in the form of lesions, including cyclobutane pyrimidine dimers (CPDs). Disruption of the functional ... ...

    Abstract Ultraviolet B (UVB) radiation represents a major carcinogen for the development of all skin cancer types. Mechanistically, UVB induces damage to DNA in the form of lesions, including cyclobutane pyrimidine dimers (CPDs). Disruption of the functional repair processes, such as nucleotide excision repair (NER), allows persistence of DNA damage and contributes to skin carcinogenesis. Recent work has implicated m
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.13904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identification and characterization of yellow stripe-like genes in maize suggest their roles in the uptake and transport of zinc and iron.

    Song, Zizhao / Li, Suzhen / Li, Yu / Zhou, Xiaojin / Liu, Xiaoqing / Yang, Wenzhu / Chen, Rumei

    BMC plant biology

    2024  Volume 24, Issue 1, Page(s) 3

    Abstract: Background: Yellow Stripe-Like (YSL) proteins are involved in the uptake and transport of metal ions. They play important roles in maintaining the zinc and iron homeostasis in Arabidopsis, rice (Oryza sativa), and barley (Hordeum vulgare). However, ... ...

    Abstract Background: Yellow Stripe-Like (YSL) proteins are involved in the uptake and transport of metal ions. They play important roles in maintaining the zinc and iron homeostasis in Arabidopsis, rice (Oryza sativa), and barley (Hordeum vulgare). However, proteins in this family have not been fully identified and comprehensively analyzed in maize (Zea mays L.).
    Results: In this study, we identified 19 ZmYSLs in the maize genome and analyzed their structural features. The results of a phylogenetic analysis showed that ZmYSLs are homologous to YSLs of Arabidopsis and rice, and these proteins are divided into four independent branches. Although their exons and introns have structural differences, the motif structure is relatively conserved. Analysis of the cis-regulatory elements in the promoters indicated that ZmYSLs might play a role in response to hypoxia and light. The results of RNA sequencing and quantitative real-time PCR analysis revealed that ZmYSLs are expressed in various tissues and respond differently to zinc and iron deficiency. The subcellular localization of ZmYSLs in the protoplast of maize mesophyll cells showed that they may function in the membrane system.
    Conclusions: This study provided important information for the further functional analysis of ZmYSL, especially in the spatio-temporal expression and adaptation to nutrient deficiency stress. Our findings provided important genes resources for the maize biofortification.
    MeSH term(s) Iron/metabolism ; Zinc/metabolism ; Zea mays/metabolism ; Arabidopsis/metabolism ; Phylogeny ; Plant Proteins/metabolism ; Gene Expression Regulation, Plant
    Chemical Substances Iron (E1UOL152H7) ; Zinc (J41CSQ7QDS) ; Plant Proteins
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059868-3
    ISSN 1471-2229 ; 1471-2229
    ISSN (online) 1471-2229
    ISSN 1471-2229
    DOI 10.1186/s12870-023-04691-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity.

    Yang, Zizhao / Wilkinson, Emma / Cui, Yan-Hong / Li, Haixia / He, Yu-Ying

    Toxicology and applied pharmacology

    2023  Volume 477, Page(s) 116688

    Abstract: Chemical modifications in messenger RNA (mRNA) regulate gene expression and play critical roles in stress responses and diseases. Recently we have shown that ... ...

    Abstract Chemical modifications in messenger RNA (mRNA) regulate gene expression and play critical roles in stress responses and diseases. Recently we have shown that N
    MeSH term(s) Animals ; Mice ; DNA Damage ; DNA Repair ; Ultraviolet Rays/adverse effects ; Skin Neoplasms/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
    Chemical Substances RNA, Messenger
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 204477-8
    ISSN 1096-0333 ; 0041-008X
    ISSN (online) 1096-0333
    ISSN 0041-008X
    DOI 10.1016/j.taap.2023.116688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.

    Yang, Fan / Kou, Junjie / Liu, Zizhao / Li, Wei / Du, Wenjing

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 655889

    Abstract: Oncogene c- ...

    Abstract Oncogene c-
    Language English
    Publishing date 2021-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.655889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Corrigendum: MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE.

    Yang, Fan / Kou, Junjie / Liu, Zizhao / Li, Wei / Du, Wenjing

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 705769

    Abstract: This corrects the article DOI: 10.3389/fcell.2021.655889.]. ...

    Abstract [This corrects the article DOI: 10.3389/fcell.2021.655889.].
    Language English
    Publishing date 2021-06-09
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.705769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum

    Fan Yang / Junjie Kou / Zizhao Liu / Wei Li / Wenjing Du

    Frontiers in Cell and Developmental Biology, Vol

    MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE

    2021  Volume 9

    Keywords cholesterol synthesis ; cell proliferation ; cancer ; SQLE ; MYC ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Identifying the core residual symptom in patients with major depressive disorder using network analysis and illustrating its association with prognosis: A study based on the national cohorts in China.

    Zhou, Jingjing / Zhou, Jia / Feng, Zizhao / Feng, Lei / Xiao, Le / Chen, Xu / Yang, Jian / Feng, Yuan / Wang, Gang

    General hospital psychiatry

    2024  Volume 87, Page(s) 68–76

    Abstract: Objective: To identify the core residual symptom of MDD and assess its relationship with patients' long-term outcomes.: Method: All patients were administered antidepressants during the acute phase and treated continuously. The 521 patients remitted ... ...

    Abstract Objective: To identify the core residual symptom of MDD and assess its relationship with patients' long-term outcomes.
    Method: All patients were administered antidepressants during the acute phase and treated continuously. The 521 patients remitted at month 6 of a multicenter prospective project were included. Remission was defined as a Quick Inventory of Depressive Symptoms-Self-Report total score of ≤5. Functional impairments were measured with the Sheehan Disability Scale, quality of life with the Quality of Life Enjoyment and Satisfaction Questionnaire - short form, and family burden with the Family Burden Scale of Disease. Visits were scheduled at baseline, weeks 2, 8, 12, and month 6.
    Results: Difficulty with concentration/decision making was the core residual symptom of MDD, determined with the centrality measure of network analysis. It was positively associated with functional impairments and family burden (r = 0.35, P < 0.01 and r = 0.31, P < 0.01, respectively) and negatively associated with life satisfaction (r = -0.29, P < 0.01). The exhibition of this residual symptom was associated with a family history of psychiatric disorders (OR = 2.610 [1.242-5.485]).
    Conclusions: The core residual symptom of MDD, difficulty with concentration/decision making, is associated with poorer social functioning, heavier family burden, and lower life satisfaction. Early detection and intervention of this symptom may be beneficial.
    Clinical trials registration number: (Chinese Clinical Trials.gov identifier) ChiCTR-OOC-17012566 and ChiCTR-INR-17012574.
    MeSH term(s) Humans ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/epidemiology ; Depressive Disorder, Major/drug therapy ; Quality of Life/psychology ; Prospective Studies ; Antidepressive Agents/therapeutic use ; Self Report
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 392299-6
    ISSN 1873-7714 ; 0163-8343
    ISSN (online) 1873-7714
    ISSN 0163-8343
    DOI 10.1016/j.genhosppsych.2024.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1584: Show issues Location:
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  8. Article ; Online: Design of a Tomato Sorting Device Based on the Multisine-FSR Composite Measurement

    Yang, Zizhao / Amin, Ahmed / Zhang, Yongnian / Wang, Xiaochan / Chen, Guangming / Abdelhamid, Mahmoud A.

    Agronomy. 2023 June 30, v. 13, no. 7

    2023  

    Abstract: The ripeness of tomatoes is crucial to determining their shelf life and quality. Most of the current methods for picking and sorting tomatoes take a long time, so this paper aims to design a device for sorting tomatoes based on force and bioelectrical ... ...

    Abstract The ripeness of tomatoes is crucial to determining their shelf life and quality. Most of the current methods for picking and sorting tomatoes take a long time, so this paper aims to design a device for sorting tomatoes based on force and bioelectrical impedance measurement. A force sensor installed on each of its four fingers may be used as an impedance measurement electrode. When picking tomatoes, the electrical impedance analysis circuit is first connected for pre-grasping. By applying a certain pre-tightening force, the FSR sensor on the end effector finger can be tightly attached to the tomato and establish an electric current pathway. Then, the electrical parameters of the tomato are measured to determine its maturity, and some of the electrical parameters are used for force monitoring compensation. Then, a force analysis is conducted to consider the resistance of the FSR under current stress. According to the principle of complex impedance circuit voltage division, the voltage signal on the tomato is determined. At the same time, the specific value of the grasping force at this time is determined based on the calibration of the pre-experiment and the compensation during the detection process, achieving real-time detection of the grasping force. The bioelectricity parameters of tomatoes can not only judge the ripeness of tomatoes, but also compensate for the force measurement stage to achieve more accurate non-destructive sorting. The experimental results showed that within 0.6 s of stable grasping, this system could complete tomato ripeness detection, improve the overall tomato sorting efficiency, and achieve 95% accuracy in identifying ripeness through impedance.
    Keywords agronomy ; bioelectrical impedance ; bioelectricity ; calibration ; electric current ; electric potential difference ; electrodes ; shelf life ; tomatoes
    Language English
    Dates of publication 2023-0630
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2607043-1
    ISSN 2073-4395
    ISSN 2073-4395
    DOI 10.3390/agronomy13071778
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Day-ahead dispatch approach for cascaded hydropower-photovoltaic complementary system based on two-stage robust optimization

    Wang, Zizhao / Wu, Feng / Li, Yang / Li, Jingyan / Liu, Ying / Liu, Wenge

    Energy. 2023 Feb., v. 265 p.126145-

    2023  

    Abstract: Cascade hydropower (CHP) is widely used to increase the integration of photovoltaic (PV) power in recent years. However, the randomness and variability of PV power output might cause power imbalances between generation plan and integrated power of ... ...

    Abstract Cascade hydropower (CHP) is widely used to increase the integration of photovoltaic (PV) power in recent years. However, the randomness and variability of PV power output might cause power imbalances between generation plan and integrated power of complementary systems. It is crucial to provide robust day-ahead schemes to ensure sufficient adjustment capability of CHPs. In this paper, a day-ahead dispatch model is established for the CHP-PV complementary system to address the PV uncertainties based on the two-stage robust optimization approach. The uncertain PV power output is described by an ambiguity set without accurate probabilistic information. Two different stages in the dispatch model are integrated into a holistic optimization problem. In the first stage, the day-ahead startup/shutdown and operation zone schemes for CHP are determined. In the second stage, the re-dispatch problem is performed to compensate for PV power fluctuations and minimize water consumption. The nested column-and-constraint generation (NC&CG) algorithm is employed as the exact solution methodology. Simulation studies based on a system in southwest China are conducted to validate the effectiveness of the proposed dispatch model and the solution algorithm. The numerical results show that the robust solution can accommodate various scenarios of PV power output and the power imbalance can always be reduced.
    Keywords algorithms ; energy ; models ; solar energy ; system optimization ; water power ; China ; Cascade hydropower ; Photovoltaic power uncertainty ; Day-ahead dispatch ; Two-stage robust optimization ; Nested column-and-constraint generation
    Language English
    Dates of publication 2023-02
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2022.126145
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Text-Guided Neural Network Training for Image Recognition in Natural Scenes and Medicine.

    Zhang, Zizhao / Chen, Pingjun / Shi, Xiaoshuang / Yang, Lin

    IEEE transactions on pattern analysis and machine intelligence

    2021  Volume 43, Issue 5, Page(s) 1733–1745

    Abstract: Convolutional neural networks (CNNs) are widely recognized as the foundation for machine vision systems. The conventional rule of teaching CNNs to understand images requires training images with human annotated labels, without any additional instructions. ...

    Abstract Convolutional neural networks (CNNs) are widely recognized as the foundation for machine vision systems. The conventional rule of teaching CNNs to understand images requires training images with human annotated labels, without any additional instructions. In this article, we look into a new scope and explore the guidance from text for neural network training. We present two versions of attention mechanisms to facilitate interactions between visual and semantic information and encourage CNNs to effectively distill visual features by leveraging semantic features. In contrast to dedicated text-image joint embedding methods, our method realizes asynchronous training and inference behavior: a trained model can classify images, irrespective of the text availability. This characteristic substantially improves the model scalability to multiple (multimodal) vision tasks. We also apply the proposed method onto medical imaging, which learns from richer clinical knowledge and achieves attention-based interpretable decision-making. With comprehensive validation on two natural and two medical datasets, we demonstrate that our method can effectively make use of semantic knowledge to improve CNN performance. Our method performs substantial improvement on medical image datasets. Meanwhile, it achieves promising performance for multi-label image classification and caption-image retrieval as well as excellent performance for phrase-based and multi-object localization on public benchmarks.
    MeSH term(s) Algorithms ; Diagnostic Imaging ; Humans ; Neural Networks, Computer
    Language English
    Publishing date 2021-04-01
    Publishing country United States
    Document type Journal Article
    ISSN 1939-3539
    ISSN (online) 1939-3539
    DOI 10.1109/TPAMI.2019.2955476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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