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  1. Article: Rezensionen. Claudius Stein: Spannungsfelder der Krisenintervention - Ein Handbuch für die psychosoziale Praxis

    Ortiz-Müller, Wolf

    Verhaltenstherapie & psychosoziale Praxis

    2021  Volume 53, Issue 2, Page(s) 413

    Language German
    Document type Article
    ZDB-ID 627290-3
    ISSN 0721-7234
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2623: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Redo Laparoscopic Gastric Bypass in a Patient with Intestinal Malrotation: Report of a Case and Video Vignette.

    Bohlmann, Ingeborg / Müller, Werner / Schuster, Antonius / Falch, Claudius

    Obesity surgery

    2023  Volume 33, Issue 8, Page(s) 2620–2624

    Abstract: Unknown intestinal rotation anomaly poses a challenge in laparoscopic gastric bypass surgery. We present a case of a patient with intestinal non-rotation that stayed undetected throughout performing a laparoscopic Roux-en-Y gastric bypass. As a result, ... ...

    Abstract Unknown intestinal rotation anomaly poses a challenge in laparoscopic gastric bypass surgery. We present a case of a patient with intestinal non-rotation that stayed undetected throughout performing a laparoscopic Roux-en-Y gastric bypass. As a result, the alimentary limb was constructed in an anti-peristaltic way, and the whole gastric bypass was located far more distally than usual. Postoperatively, the patient presented with recurring nausea and vomiting. After several diagnostic steps, a computed tomography finally revealed the inadvertently reverse directed gastric bypass and the pre-existing condition of intestinal non-rotation. This was followed by a diagnostic laparoscopy and the reconstruction of the gastric bypass in "mirrored" technique.
    MeSH term(s) Humans ; Gastric Bypass/methods ; Obesity, Morbid/surgery ; Intestinal Volvulus/diagnostic imaging ; Intestinal Volvulus/surgery ; Laparoscopy/methods
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Case Reports ; Video-Audio Media ; Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06694-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3381: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Seroconversion Rates After the Second COVID-19 Vaccination in Patients With Systemic Light Chain (AL) amyloidosis.

    Liebers, Nora / Schönland, Stefan O / Speer, Claudius / Edelmann, Dominic / Schnitzler, Paul / Kräusslich, Hans-Georg / Mueller-Tidow, Carsten / Hegenbart, Ute / Dietrich, Sascha

    HemaSphere

    2022  Volume 6, Issue 3, Page(s) e688

    Language English
    Publishing date 2022-02-15
    Publishing country United States
    Document type Journal Article
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Solid Pin Protein Array Printing Platforms.

    Espina, Virginia / Mueller, Claudius

    Advances in experimental medicine and biology

    2019  Volume 1188, Page(s) 61–75

    Abstract: Reverse phase protein arrays (RPPA) are miniature dot blots constructed using robotic arrayers to deposit protein containing samples onto nitrocellulose-coated glass slides. Reverse phase protein arrays address the challenge of quantifying low-abundance ... ...

    Abstract Reverse phase protein arrays (RPPA) are miniature dot blots constructed using robotic arrayers to deposit protein containing samples onto nitrocellulose-coated glass slides. Reverse phase protein arrays address the challenge of quantifying low-abundance proteins and posttranslationally modified proteins in cellular lysates and body fluids. RPPA technology is ideally suited to biomarker discovery, signal pathway profiling, functional phenotype analysis, and mechanism of action studies for drug discovery. Each array is fabricated with specimens, controls, and calibrators, thus providing a complete assay on each slide. Constructing a reverse phase protein array initially consists of selecting an arrayer, pin type, print head configuration, and nitrocellulose slide that is optimized for the particular specimen type and protein detection method. Herein we present the nuances of RPPA fabrication and study design using a solid pin arrayer and nitrocellulose-coated slides.
    MeSH term(s) Collodion ; Drug Discovery/instrumentation ; Drug Discovery/trends ; Printing, Three-Dimensional ; Protein Array Analysis/instrumentation ; Proteins/chemistry
    Chemical Substances Proteins ; Collodion (9004-70-0)
    Language English
    Publishing date 2019-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-32-9755-5_4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: It is in your face-Alexithymia impairs facial mimicry.

    Franz, Matthias / Nordmann, Marc A / Rehagel, Claudius / Schäfer, Ralf / Müller, Tobias / Lundqvist, Daniel

    Emotion (Washington, D.C.)

    2021  Volume 21, Issue 7, Page(s) 1537–1549

    Abstract: Alexithymia is characterized by a reduced ability to identify and differentiate emotional aspects of social interaction. In this study we investigated, for the first time, whether alexithymia impairs facial mimicry in response to dynamic naturalistic ... ...

    Abstract Alexithymia is characterized by a reduced ability to identify and differentiate emotional aspects of social interaction. In this study we investigated, for the first time, whether alexithymia impairs facial mimicry in response to dynamic naturalistic facial affect expressions. Potential volunteers were recruited by means of an online survey (
    MeSH term(s) Affective Symptoms ; Humans
    Language English
    Publishing date 2021-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2102391-8
    ISSN 1931-1516 ; 1528-3542
    ISSN (online) 1931-1516
    ISSN 1528-3542
    DOI 10.1037/emo0001002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects.

    Aicher, Helena D / Mueller, Michael J / Dornbierer, Dario A / Suay, Dila / Elsner, Claudius / Wicki, Ilhui / Meling, Daniel / Caflisch, Luzia / Hempe, Alexandra / Steinhart, Camilla / Mueller, Jovin / Von Rotz, Robin / Kleim, Birgit / Scheidegger, Milan

    Frontiers in psychiatry

    2024  Volume 14, Page(s) 1302559

    Abstract: Background: There is growing scientific evidence for the therapeutic benefits of the Amazonian plant-based psychedelic "ayahuasca" for neuropsychiatric disorders such as depression and anxiety. However, there are certain challenges when incorporating ... ...

    Abstract Background: There is growing scientific evidence for the therapeutic benefits of the Amazonian plant-based psychedelic "ayahuasca" for neuropsychiatric disorders such as depression and anxiety. However, there are certain challenges when incorporating botanical ayahuasca into biomedical research and clinical therapy environments. Formulations inspired by ayahuasca, which contain specific and standardized active components, are a potential remedy.
    Methods: We investigated subjective acute and persisting effects of a novel formulation containing the reversible monoamine oxidase inhibitor harmine (orodispersible tablet containing 100 mg MAO-I) and N,N-dimethyltryptamine (incremental intranasal dosing of up to 100 mg DMT), compared with two other conditions, namely harmine alone and placebo, in a crossover RCT in 31 healthy male subjects.
    Results: DMT + harmine, but not harmine alone, induced a psychedelic experience assessed with the 5D-ASC rating scale [global score:
    Discussion and conclusion: Our results suggest that the experience induced by the standardized DMT + harmine formulation induces a phenomenologically rich psychedelic experience, demonstrates good psychological safety and tolerability, is well tolerated, and induces beneficial psychological processes that could possibly support psychotherapy. Further studies are required to investigate the psychotherapeutic potential in patients.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1302559
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Kaiser Flavius Claudius Julianus

    Müller, Eugen

    Biographie nebst Auswahl seiner Schriften

    1901  

    Author's details von Eugen Müller
    Language German
    Size 136 S
    Publisher Rehtmeyer
    Publishing place Hannover
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article ; Online: Using Laser Capture Microdissection to Isolate Cortical Laminae in Nonhuman Primate Brain.

    Corgiat, Brian A / Mueller, Claudius

    Methods in molecular biology (Clifton, N.J.)

    2017  Volume 1606, Page(s) 115–132

    Abstract: Laser capture microdissection (LCM) is a technique that allows procurement of an enriched cell population from a heterogeneous tissue sample under direct microscopic visualization. Fundamentally, laser capture microdissection consists of three main steps: ...

    Abstract Laser capture microdissection (LCM) is a technique that allows procurement of an enriched cell population from a heterogeneous tissue sample under direct microscopic visualization. Fundamentally, laser capture microdissection consists of three main steps: (1) visualizing the desired cell population by microscopy, (2) melting a thermolabile polymer onto the desired cell populations using infrared laser energy to form a polymer-cell composite (capture method) or photovolatizing a region of tissue using ultraviolet laser energy (cutting method), and (3) removing the desired cell population from the heterogeneous tissue. In this chapter, we discuss the infrared capture method only. LCM technology is compatible with a wide range of downstream applications such as mass spectrometry, DNA genotyping and RNA transcript profiling, cDNA library generation, proteomics discovery, and signal pathway mapping. This chapter profiles the ArcturusXT
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-6990-6_8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  9. Article: Combining the "Sibling Technologies" of Laser Capture Microdissection and Reverse Phase Protein Microarrays.

    Mueller, Claudius / Davis, Justin B / Liotta, Lance A

    Advances in experimental medicine and biology

    2019  Volume 1188, Page(s) 95–111

    Abstract: Reverse phase protein microarrays (RPPA) and laser capture microdissection (LCM) are "sibling" technologies that originated from the same laboratory to overcome the challenge of quantifying low-abundance proteins in heterogeneous tissues. Combining both ... ...

    Abstract Reverse phase protein microarrays (RPPA) and laser capture microdissection (LCM) are "sibling" technologies that originated from the same laboratory to overcome the challenge of quantifying low-abundance proteins in heterogeneous tissues. Combining both technologies provides both unique opportunities and unique challenges. Enabling the unprecedented resolution of the activation state of labile biomarkers, such as phosphorylated cell signaling proteins, has had a substantial impact on our understanding of diseases and is playing a significant role in clinical trials. At the same time, quantifying proteins at this sensitivity in very small amounts of material requires cognizance of pre-analytical variability and the limits of downstream detection technologies. Here, we discuss both the potential that the combination of both technologies presents and the potential pitfalls that must be navigated.
    MeSH term(s) Laser Capture Microdissection ; Protein Array Analysis/methods ; Protein Array Analysis/standards ; Protein Array Analysis/trends ; Proteins/chemistry ; Technology/trends
    Chemical Substances Proteins
    Language English
    Publishing date 2019-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-32-9755-5_6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A resample-replace lasso procedure for combining high-dimensional markers with limit of detection.

    Wang, Jinjuan / Zhao, Yunpeng / Tang, Larry L / Mueller, Claudius / Li, Qizhai

    Journal of applied statistics

    2021  Volume 49, Issue 16, Page(s) 4278–4293

    Abstract: In disease screening, a biomarker combination developed by combining multiple markers tends to have a higher sensitivity than an individual marker. Parametric methods for marker combination rely on the inverse of covariance matrices, which is often a non- ...

    Abstract In disease screening, a biomarker combination developed by combining multiple markers tends to have a higher sensitivity than an individual marker. Parametric methods for marker combination rely on the inverse of covariance matrices, which is often a non-trivial problem for high-dimensional data generated by modern high-throughput technologies. Additionally, another common problem in disease diagnosis is the existence of limit of detection (LOD) for an instrument - that is, when a biomarker's value falls below the limit, it cannot be observed and is assigned an NA value. To handle these two challenges in combining high-dimensional biomarkers with the presence of LOD, we propose a resample-replace lasso procedure. We first impute the values below LOD and then use the graphical lasso method to estimate the means and precision matrices for the high-dimensional biomarkers. The simulation results show that our method outperforms alternative methods such as either substitute NA values with LOD values or remove observations that have NA values. A real case analysis on a protein profiling study of glioblastoma patients on their survival status indicates that the biomarker combination obtained through the proposed method is more accurate in distinguishing between two groups.
    Language English
    Publishing date 2021-09-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476802-1
    ISSN 1360-0532 ; 0266-4763
    ISSN (online) 1360-0532
    ISSN 0266-4763
    DOI 10.1080/02664763.2021.1977785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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