LIVIVO - Search results -

Search results

Result 1 - 10 of total 222

Book: Multislice CT

Morcos, Sameh K.

(The British journal of radiology ; [N.S.],77, Spec. iss.)

2004

Author's details	ed. by S. K. Morcos
Series title	The British journal of radiology ; [N.S.],77, Spec. iss.
Collection
Language	English
Size	S. S1 - S105 : Ill., graph. Darst.
Publisher	British Inst. of Radiology
Publishing place	London
Publishing country	Great Britain
Document type	Book
HBZ-ID	HT014244778
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
Ue I Zs 11 -77,Spec.iss.-	verfügbar in Königswinter	Königswinter

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: Effective pruning of web-scale datasets based on complexity of concept clusters

Abbas, Amro / Rusak, Evgenia / Tirumala, Kushal / Brendel, Wieland / Chaudhuri, Kamalika / Morcos, Ari S.

2024

Abstract: Utilizing massive web-scale datasets has led to unprecedented performance gains in machine learning models, but also imposes outlandish compute requirements for their training. In order to improve training and data efficiency, we here push the limits of ... ...

Abstract	Utilizing massive web-scale datasets has led to unprecedented performance gains in machine learning models, but also imposes outlandish compute requirements for their training. In order to improve training and data efficiency, we here push the limits of pruning large-scale multimodal datasets for training CLIP-style models. Today's most effective pruning method on ImageNet clusters data samples into separate concepts according to their embedding and prunes away the most prototypical samples. We scale this approach to LAION and improve it by noting that the pruning rate should be concept-specific and adapted to the complexity of the concept. Using a simple and intuitive complexity measure, we are able to reduce the training cost to a quarter of regular training. By filtering from the LAION dataset, we find that training on a smaller set of high-quality data can lead to higher performance with significantly lower training costs. More specifically, we are able to outperform the LAION-trained OpenCLIP-ViT-B32 model on ImageNet zero-shot accuracy by 1.1p.p. while only using 27.7% of the data and training compute. Despite a strong reduction in training cost, we also see improvements on ImageNet dist. shifts, retrieval tasks and VTAB. On the DataComp Medium benchmark, we achieve a new state-of-the-art ImageNet zero-shot accuracy and a competitive average zero-shot accuracy on 38 evaluation tasks. Comment: Oral at the DataComp Workshop, ICCV 2023
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2024-01-09
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Book ; Online: SemDeDup

Abbas, Amro / Tirumala, Kushal / Simig, Dániel / Ganguli, Surya / Morcos, Ari S.

Data-efficient learning at web-scale through semantic deduplication

2023

Abstract: Progress in machine learning has been driven in large part by massive increases in data. However, large web-scale datasets such as LAION are largely uncurated beyond searches for exact duplicates, potentially leaving much redundancy. Here, we introduce ... ...

Abstract	Progress in machine learning has been driven in large part by massive increases in data. However, large web-scale datasets such as LAION are largely uncurated beyond searches for exact duplicates, potentially leaving much redundancy. Here, we introduce SemDeDup, a method which leverages embeddings from pre-trained models to identify and remove semantic duplicates: data pairs which are semantically similar, but not exactly identical. Removing semantic duplicates preserves performance and speeds up learning. Analyzing a subset of LAION, we show that SemDeDup can remove 50% of the data with minimal performance loss, effectively halving training time. Moreover, performance increases out of distribution. Also, analyzing language models trained on C4, a partially curated dataset, we show that SemDeDup improves over prior approaches while providing efficiency gains. SemDeDup provides an example of how simple ways of leveraging quality embeddings can be used to make models learn faster with less data.
Keywords	Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2023-03-16
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Contrast-induced nephropathy: are there differences between low osmolar and iso-osmolar iodinated contrast media?

Morcos, S K

Clinical radiology

2009 Volume 64, Issue 5, Page(s) 468–472

Abstract: It is acknowledged that high osmolar contrast media are more nephrotoxic than low (LOCM) or iso-osmolar contrast media (IOCM). However, it remains contentious whether the IOCM are less nephrotoxic in comparison with LOCM. This article reviews published ... ...

Abstract	It is acknowledged that high osmolar contrast media are more nephrotoxic than low (LOCM) or iso-osmolar contrast media (IOCM). However, it remains contentious whether the IOCM are less nephrotoxic in comparison with LOCM. This article reviews published clinical studies that investigated this issue and demonstrates there are no conclusive data to indicate that there is a definite difference in renal tolerance between LOCM and IOCM. All these agents are potentially nephrotoxic in patients with advanced renal impairment. In these patients the smallest possible dose of IOCM or LOCM should be used in addition to adequate hydration to minimize the risk of contrast nephropathy.
MeSH term(s)	Contrast Media/administration & dosage ; Contrast Media/chemistry ; Contrast Media/toxicity ; Humans ; Injections, Intra-Arterial ; Injections, Intravenous ; Iodine Isotopes/administration & dosage ; Iodine Isotopes/toxicity ; Kidney Diseases/chemically induced ; Osmolar Concentration ; Risk Factors
Chemical Substances	Contrast Media ; Iodine Isotopes
Language	English
Publishing date	2009-05
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	391227-9
ISSN	1365-229X ; 0009-9260
ISSN (online)	1365-229X
ISSN	0009-9260
DOI	10.1016/j.crad.2008.08.019
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ue I Zs.201: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Is MRI Overutilized for Evaluation of Knee Pain in Veterans?

Koenig, Scott / Morcos, George / Gopinath, Rohan / Wang, Kenneth / Henn, Frank / Leong, Natalie L

The journal of knee surgery

2021 Volume 36, Issue 3, Page(s) 305–309

Abstract: MRI is an essential diagnostic imaging modality for many knee conditions; however, it is not indicated in the setting of advanced knee arthritis. Inappropriate MRI imaging adds to health care costs and may delay definitive management for many patients. ... ...

Abstract	MRI is an essential diagnostic imaging modality for many knee conditions; however, it is not indicated in the setting of advanced knee arthritis. Inappropriate MRI imaging adds to health care costs and may delay definitive management for many patients. The primary purpose of this study was to ascertain the frequency of inappropriate MRI scans performed at one Veterans' Administration Medical Center (VAMC). We performed a retrospective chart review of all knee MRIs ordered over a 6-month period. Inappropriate MRI was defined as MRI performed prior to radiographs (XRs), or in the presence of XRs demonstrating severe osteoarthritis, without leading to a nonarthroplasty procedure of the knee. Of the 304 cases reviewed, 36.8% (112) of the MRIs were deemed inappropriate, 33 were ordered by orthopedists, and 79 were ordered by other health care providers. Of the 33 ordered by orthopedists, 25 were ordered by retired/nonsurgical orthopedists. Obtaining an MRI delayed care by an average of 29.2 days. Of the 252 cases that had XR prior to MRI, none included all four views in the standard knee XR series and only four had weightbearing images. Over a third of knee MRIs performed at this VAMC were inappropriate and delayed care. Additionally, no XRs in our study contained all the necessary views to properly assess knee arthritis. These concerning findings signify a potential opportunity for education in diagnostic strategies, to better patient care and resource utilization in the VAMC.
MeSH term(s)	Humans ; Retrospective Studies ; Veterans ; Pain ; Magnetic Resonance Imaging ; Osteoarthritis
Language	English
Publishing date	2021-09-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2075354-8
ISSN	1938-2480 ; 1538-8506 ; 0899-7403
ISSN (online)	1938-2480
ISSN	1538-8506 ; 0899-7403
DOI	10.1055/s-0041-1733880
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3867: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Extracellular gadolinium contrast agents: differences in stability.

Morcos, S K

European journal of radiology

2008 Volume 66, Issue 2, Page(s) 175–179

Abstract: Extracellular gadolinium contrast agents (Gd-CA) are either linear or macrocyclic chelates available as ionic or non-ionic preparations. The molecular structure whether cyclic or linear and ionicity determines the stability of Gd-CA. Linear chelates are ... ...

Abstract	Extracellular gadolinium contrast agents (Gd-CA) are either linear or macrocyclic chelates available as ionic or non-ionic preparations. The molecular structure whether cyclic or linear and ionicity determines the stability of Gd-CA. Linear chelates are flexible open chains which do not offer a strong binding to Gd(3+). In contrast, the macrocyclic chelates offer a strong binding to Gd(3+) by the virtue of being preorganized rigid rings of almost optimal size to cage the gadolinium atom. Non-ionic preparations are also less stable in comparison to the ionic ones as the binding between Gd(3+) with the negatively charged carboxyl groups is stronger in comparison to that with amides or alcohol in the non-ionic preparations. According to stability constants and kinetic measurements, the most stable Gd-CM is the ionic-macrocyclic chelate Gd-DOTA and the least stable agents are the non-ionic linear chelates gadodiamide and gadoversetamide. In vivo data confirmed the low stability of non-ionic linear chelates but no significant difference was observed amongst the macrocyclic agents whether ionic (Gd-DOTA) or non-ionic such as Gd-HP-DO3A and Gd-BT-DO3A. The stability of Gd-CA seems to be an important factor in the pathogenesis of the serious complication of nephrogenic systemic fibrosis. Gd-CA of low stability are likely to undergo transmetallation and release free Gd ions that deposit in tissue and attract circulating fibrocytes to initiate the process of fibrosis. No cases of NSF have been observed so far after the exclusive use of the stable macrocyclic Gd-CA.
MeSH term(s)	Contrast Media/adverse effects ; Contrast Media/chemistry ; Drug Stability ; Fibrosis/chemically induced ; Gadolinium/adverse effects ; Gadolinium/chemistry ; Humans ; Kidney Diseases/chemically induced ; Magnetic Resonance Imaging ; Skin Diseases/chemically induced
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Keywords	covid19
Language	English
Publishing date	2008-05
Publishing country	Ireland
Document type	Comparative Study ; Journal Article ; Review
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2008.01.025
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1630: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: FLASH Proton Radiation Therapy Mitigates Inflammatory and Fibrotic Pathways and Preserves Cardiac Function in a Preclinical Mouse Model of Radiation-Induced Heart Disease.

Kim, Kyle / Kim, Michele M / Skoufos, Giorgos / Diffenderfer, Eric S / Motlagh, Seyyedeh Azar Oliaei / Kokkorakis, Michail / Koliaki, Ilektra / Morcos, George / Shoniyozov, Khayrullo / Griffin, Joanna / Hatzigeorgiou, Artemis G / Metz, James M / Lin, Alexander / Feigenberg, Steven J / Cengel, Keith A / Ky, Bonnie / Koumenis, Constantinos / Verginadis, Ioannis I

International journal of radiation oncology, biology, physics

2024

Abstract: ... 40 Gy/s, known as "FLASH" radiation therapy, enhances the therapeutic index of radiation therapy (RT ... conventional) proton RT (S-PRT), as evidenced by reduced acute and chronic cardiac toxicities.: Methods and ... or S-PRT, at 2 weeks after a single 40 Gy dose. Inflammatory responses were assessed ...

Abstract	Purpose: Studies during the past 9 years suggest that delivering radiation at dose rates exceeding 40 Gy/s, known as "FLASH" radiation therapy, enhances the therapeutic index of radiation therapy (RT) by decreasing normal tissue damage while maintaining tumor response compared with conventional (or standard) RT. This study demonstrates the cardioprotective benefits of FLASH proton RT (F-PRT) compared with standard (conventional) proton RT (S-PRT), as evidenced by reduced acute and chronic cardiac toxicities. Methods and materials: Mice were imaged using cone beam computed tomography to precisely determine the heart's apex as the beam isocenter. Irradiation was conducted using a shoot-through technique with a 5-mm diameter circular collimator. Bulk RNA-sequencing was performed on nonirradiated samples, as well as apexes treated with F-PRT or S-PRT, at 2 weeks after a single 40 Gy dose. Inflammatory responses were assessed through multiplex cytokine/chemokine microbead assay and immunofluorescence analyses. Levels of perivascular fibrosis were quantified using Masson's Trichrome and Picrosirius red staining. Additionally, cardiac tissue functionality was evaluated by 2-dimensional echocardiograms at 8- and 30-weeks post-PRT. Results: Radiation damage was specifically localized to the heart's apex. RNA profiling of cardiac tissues treated with PRT revealed that S-PRT uniquely upregulated pathways associated with DNA damage response, induction of tumor necrosis factor superfamily, and inflammatory response, and F-PRT primarily affected cytoplasmic translation, mitochondrion organization, and adenosine triphosphate synthesis. Notably, F-PRT led to a milder inflammatory response, accompanied by significantly attenuated changes in transforming growth factor β1 and α smooth muscle actin levels. Critically, F-PRT decreased collagen deposition and better preserved cardiac functionality compared with S-PRT. Conclusions: This study demonstrated that F-PRT reduces the induction of an inflammatory environment with lower expression of inflammatory cytokines and profibrotic factors. Importantly, the results indicate that F-PRT better preserves cardiac functionality, as confirmed by echocardiography analysis, while also mitigating the development of long-term fibrosis.
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	197614-x
ISSN	1879-355X ; 0360-3016
ISSN (online)	1879-355X
ISSN	0360-3016
DOI	10.1016/j.ijrobp.2024.01.224
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1218: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Real-world effectiveness of elexacaftor/tezacaftor/ivacaftor on the burden of illness in adolescents and adults with cystic fibrosis.

Keens, Thomas / Hoffman, Veena / Topuria, Ia / Elder, Ken / Cerf, Shannon / Mulder, Kyra / Roberts, Jon / Lysinger, Jerimiah / Del Carmen Reyes, Maria / Berdella, Maria / Cairns, Anne Marie / Jain, Manu / Ganapathy, Vaidyanathan / Lou, Yiyue / Morcos, Bassem / Wu, Chuntao / Sass, Laura

Heliyon

2024 Volume 10, Issue 7, Page(s) e28508

Abstract: Background: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) has been shown to be safe and efficacious in people with cystic fibrosis (CF) aged ≥2 years. Here, we describe results from an observational study assessing change in burden of illness following ...

Abstract	Background: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) has been shown to be safe and efficacious in people with cystic fibrosis (CF) aged ≥2 years. Here, we describe results from an observational study assessing change in burden of illness following initiating ELX/TEZ/IVA in real-world settings. Methods: This US-based, multicenter, observational study used data from electronic medical records to evaluate real-world burden of illness before and after ELX/TEZ/IVA initiation in people with CF aged ≥12 years heterozygous for Results: Overall, 206 people with CF were enrolled (mean [SD] age 22.5 [11.1] years; 192 [93.2%] with Conclusions: ELX/TEZ/IVA treatment was associated with improved lung function, increased BMI, reduced frequency of PEx, and improved (i.e., reduced) HbA1c. These results confirm the broad clinical benefits of ELX/TEZ/IVA seen in clinical trials and show the potential for ELX/TEZ/IVA to improve markers of glucose metabolism.
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e28508
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Nephrogenic systemic fibrosis following the administration of extracellular gadolinium based contrast agents: is the stability of the contrast agent molecule an important factor in the pathogenesis of this condition?

Morcos, S K

The British journal of radiology

2007 Volume 80, Issue 950, Page(s) 73–76

MeSH term(s)	Contrast Media/adverse effects ; Contrast Media/chemistry ; Fibrosis/chemically induced ; Gadolinium/adverse effects ; Gadolinium/chemistry ; Humans ; Kidney Failure, Chronic/complications ; Scleroderma, Systemic/chemically induced ; Skin/pathology
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2007-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr/17111243
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ue I Zs.11: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The Relationship Between Dental Agenesis and Maxillary Hypoplasia in Patients With Cleft Lip and Palate.

Janes, Lindsay E / Bazina, Mohamed / Morcos, Sherif S / Ukaigwe, Angelica / Valiathan, Manish / Jacobson, Ronald / Gosain, Arun K

The Journal of craniofacial surgery

2021 Volume 32, Issue 6, Page(s) 2012–2015

Abstract: Abstract: Both dental agenesis and maxillary growth restriction are well-recognized sequelae in patients with unilateral cleft lip and palate, but their etiology remains controversial. The aim of this study was to evaluate the relationship between ... ...

Abstract	Abstract: Both dental agenesis and maxillary growth restriction are well-recognized sequelae in patients with unilateral cleft lip and palate, but their etiology remains controversial. The aim of this study was to evaluate the relationship between hypodontia and maxillary volume. A retrospective review of patients age 6 to 9 with Veau III (unilateral) cleft palate who underwent Cone Beam Computer Tomography in preparation for alveolar bone grafting at 2 major Children's Hospitals between 2010 and 2016 was conducted and serial panoramic radiographs were reviewed. Thirty-eight patients were identified that met inclusion criteria and had adequate imaging. Group 1 ("poor growers") consisted of the bottom 50% of Sella-Nasion-A point minus Sella-Nasion-B point (ANB) angles and Group 2 ("good growers") consisted of the top 50% of ANB angles. Group 1 had a significantly higher mean number of missing teeth (1.58 ± 0.28 missing teeth) compared to Group 2 (0.74 ± 0.23 missing teeth), and significantly lower maxillary volume (12.88 ± 0.61 cm3 versus 15.24 ± 0.88 cm3, respectively). The severity of maxillary hypoplasia in cleft patients increases with increased dental agenesis. These data indicate that intrinsic factors play a significant role in maxillary growth restriction in cleft patients, independent of the sequelae of surgical intervention.
MeSH term(s)	Child ; Cleft Lip/complications ; Cleft Lip/diagnostic imaging ; Cleft Palate/complications ; Cleft Palate/diagnostic imaging ; Humans ; Maxilla/diagnostic imaging ; Retrospective Studies
Language	English
Publishing date	2021-04-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000007555
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3761: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 175: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito