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  1. Article ; Online: In situ N K-edge XANES study of iron, cobalt and nickel nitride thin films.

    Pandey, Nidhi / Gupta, Mukul / Phase, D M / Gupta, Ajay

    Journal of synchrotron radiation

    2021  Volume 28, Issue Pt 5, Page(s) 1504–1510

    Abstract: ... its sensitivity for ultra-thin films of iron-nitride (Fe-N), cobalt-nitride (Co-N) and nickel-nitride (Ni-N ... They were grown using DC-magnetron sputtering in the presence of an N ...

    Abstract A prototype in situ X-ray absorption near-edge structure (XANES) system was developed to explore its sensitivity for ultra-thin films of iron-nitride (Fe-N), cobalt-nitride (Co-N) and nickel-nitride (Ni-N). They were grown using DC-magnetron sputtering in the presence of an N
    Language English
    Publishing date 2021-08-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2021413-3
    ISSN 1600-5775 ; 0909-0495
    ISSN (online) 1600-5775
    ISSN 0909-0495
    DOI 10.1107/S1600577521006822
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  2. Book ; Online: Magnetism and structure of in-situ grown FeN films studied using N K-edge XAS and nuclear resonance scattering

    Gupta, Mukul / Pandey, Nidhi / Niti / Reddy, V. R. / Phase, D. M. / Schlage, Kai / Wille, Hans-Christian / Gupta, Ajay

    2019  

    Abstract: ... absorption near edge spectroscopy (XANES) at the N $K$-edge and nuclear resonant scattering (NRS). Films were ... features and an intense e$_g$ feature in the N $K$-edge pattern. This indicates that a structural ... of films increases beyond 5\,nm. The behavior of such N $K$-edge features correlates very well ...

    Abstract We studied the structural and magnetic properties of \textit{in-situ} grown iron mononitride (FeN) thin films. Initial stages of film growth were trapped utilizing synchrotron based soft x-ray absorption near edge spectroscopy (XANES) at the N $K$-edge and nuclear resonant scattering (NRS). Films were grown using dc-magnetron sputtering, separately at the experimental stations of SXAS beamline (BL01, Indus 2) and NRS beamline (P01, Petra III). It was found that the initial stages of film growth differs from the bulk of it. Ultrathin FeN films, exhibited larger energy separation between the t$_{2g}$ and e$_g$ features and an intense e$_g$ feature in the N $K$-edge pattern. This indicates that a structural transition is taking place from the rock-slat (RS)-type FeN to zinc-blende(ZB)-type FeN when the thickness of films increases beyond 5\,nm. The behavior of such N $K$-edge features correlates very well with the emergence of a magnetic component appearing in the NRS pattern at 100\,K in ultrathin FeN films. Combining the \textit{in-situ} XANES and NRS measurements, it appears that initial FeN layers grow in RS-type structure having a magnetic ground state. Subsequently, the structure changes to ZB-type which is known to be non-magnetic. Observed results help in resolving the long standing debate about the structure and the magnetic ground state of FeN.

    Comment: 9 pages, 5 figures
    Keywords Condensed Matter - Materials Science
    Subject code 530
    Publishing date 2019-02-09
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: THE LARGEST r FOR WHICH (n + k)!/n!(k + r)! IS AN INTEGER

    HANSRAJ GUPTA, KULDIP SINGH

    Proceedings of Indian National Science Academy, Vol 10, Iss

    2015  Volume 10

    Abstract: THE LARGEST r FOR WHICH (n + k)!/n!(k + r)! IS AN INTEGER ...

    Abstract THE LARGEST r FOR WHICH (n + k)!/n!(k + r)! IS AN INTEGER
    Keywords Science ; Q
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Indian National Science Academy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Wild-type H- and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response.

    Grabocka, Elda / Pylayeva-Gupta, Yuliya / Jones, Mathew J K / Lubkov, Veronica / Yemanaberhan, Eyoel / Taylor, Laura / Jeng, Hao Hsuan / Bar-Sagi, Dafna

    Cancer cell

    2014  Volume 25, Issue 2, Page(s) 243–256

    Abstract: ... to mutant Ras-driven tumorigenesis. Here, we show that downregulation of wild-type H-Ras or N-Ras in mutant ... K-Ras cancer cells leads to hyperactivation of the Erk/p90RSK and PI3K/Akt pathways and ... of mutant K-Ras cancer cells to DNA damage chemotherapeutic agents in vitro and in vivo. ...

    Abstract Mutations in KRAS are prevalent in human cancers and universally predictive of resistance to anticancer therapeutics. Although it is widely accepted that acquisition of an activating mutation endows RAS genes with functional autonomy, recent studies suggest that the wild-type forms of Ras may contribute to mutant Ras-driven tumorigenesis. Here, we show that downregulation of wild-type H-Ras or N-Ras in mutant K-Ras cancer cells leads to hyperactivation of the Erk/p90RSK and PI3K/Akt pathways and, consequently, the phosphorylation of Chk1 at an inhibitory site, Ser 280. The resulting inhibition of ATR/Chk1 signaling abrogates the activation of the G2 DNA damage checkpoint and confers specific sensitization of mutant K-Ras cancer cells to DNA damage chemotherapeutic agents in vitro and in vivo.
    MeSH term(s) Animals ; Antineoplastic Agents/pharmacology ; Cell Survival/drug effects ; Cell Transformation, Neoplastic/pathology ; Checkpoint Kinase 1 ; DNA Damage/drug effects ; DNA Damage/genetics ; Drug Resistance, Neoplasm ; Female ; Flow Cytometry ; GTP Phosphohydrolases/antagonists & inhibitors ; GTP Phosphohydrolases/genetics ; GTP Phosphohydrolases/metabolism ; Humans ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Nude ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Mutation/genetics ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation/drug effects ; Protein Kinases/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins p21(ras)/antagonists & inhibitors ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Ribosomal Protein S6 Kinases, 90-kDa/metabolism ; ras Proteins/genetics ; ras Proteins/metabolism
    Chemical Substances Antineoplastic Agents ; KRAS protein, human ; Membrane Proteins ; Proto-Oncogene Proteins ; Protein Kinases (EC 2.7.-) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; CHEK1 protein, human (EC 2.7.11.1) ; Checkpoint Kinase 1 (EC 2.7.11.1) ; Chek1 protein, mouse (EC 2.7.11.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Ribosomal Protein S6 Kinases, 90-kDa (EC 2.7.11.1) ; MAPK1 protein, human (EC 2.7.11.24) ; Mitogen-Activated Protein Kinase 1 (EC 2.7.11.24) ; Mitogen-Activated Protein Kinase 3 (EC 2.7.11.24) ; GTP Phosphohydrolases (EC 3.6.1.-) ; NRAS protein, human (EC 3.6.1.-) ; HRAS protein, human (EC 3.6.5.2) ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2) ; ras Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2014-02-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2078448-X
    ISSN 1878-3686 ; 1535-6108
    ISSN (online) 1878-3686
    ISSN 1535-6108
    DOI 10.1016/j.ccr.2014.01.005
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5650: Show issues Location:
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    Zs.MG 104: Show issues

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  5. Book ; Online ; E-Book: Multiple abiotic stress tolerances in higher plants

    Gupta, N. K / Shavrukov, Yuri / Singhal, R. K / Borisjuk, Nikolai

    addressing the growing challenges

    2023  

    Author's details edited by von N. K. Gupta, Yuri Shavrukov, R. K. Singhal and Nikolai Borisjuk
    Language English
    Size 1 Online-Ressource (xvi, 300 Seiten), Illustrationen
    Publisher CRC Press
    Publishing place Boca Raton, Fla
    Publishing country United States
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030395443
    ISBN 978-1-00-095825-6 ; 9781032292410 ; 1-00-095825-6 ; 1032292415
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Re: the prostatic urethral lift for the treatment of lower urinary tract symptoms associated with prostate enlargement due to benign prostatic hyperplasia: the L.I.F.T. Study. C. G. Roehrborn, S. N. Gange, N. D. Shore, J. L. Giddens, D. M. Bolton, B. E. Cowan, B. T. Brown, K. T. McVary, A. E. Te, S. S. Gholami, P. Rashid, W. G. Moseley, P. T. Chin, W. T. Dowling, S. J. Freedman, P. F. Incze, K. S. Coffield, F. D. Borges and D. B. Rukstalis J Urol 2013;190:2161-2167.

    Gupta, Saurabh / Singh, Vishwajeet / Goel, Apul

    The Journal of urology

    2014  Volume 191, Issue 6, Page(s) 1934–1935

    MeSH term(s) Humans ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/surgery ; Male ; Prostatic Hyperplasia/complications ; Suburethral Slings
    Language English
    Publishing date 2014-06
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
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    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.91: Show issues Location:
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    Zs.MO 331: Show issues

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  7. Article: Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines.

    Bernhard, E J / Stanbridge, E J / Gupta, S / Gupta, A K / Soto, D / Bakanauskas, V J / Cerniglia, G J / Muschel, R J / McKenna, W G

    Cancer research

    2000  Volume 60, Issue 23, Page(s) 6597–6600

    Abstract: ... that genetic inactivation of K- or N-ras oncogenes in human tumor cells (DLD-1 and HT1080, respectively) leads ... cells and extends this finding to the K- and N- members of the ras family. These findings support ... to increased radiosensitivity. Reintroduction of the activated N-ras gene into the HT1080 line, having lost ...

    Abstract Transformation with ras oncogenes results in increased radiation sur vival in many but not all cells. In addition, prenyltransferase inhibitors which inhibit ras proteins by blocking posttranslational modification radiosensitize cells with oncogenic ras. These findings suggest that oncogenic ras contributes to intrinsic radiation resistance. However, because introduction of ras oncogenes does not increase radiation survival in all cells and because prenyltransferase inhibitors target molecules other than ras, these studies left the conclusion that ras increases the intrinsic radi ation resistance of tumor cells in doubt. Here we show that genetic inactivation of K- or N-ras oncogenes in human tumor cells (DLD-1 and HT1080, respectively) leads to increased radiosensitivity. Reintroduction of the activated N-ras gene into the HT1080 line, having lost its mutant allele, resulted in increased radiation resistance. This study lends further support to the hypothesis that expression of activated ras can contribute to intrinsic radiation resistance in human tumor cells and extends this finding to the K- and N- members of the ras family. These findings support the development of strategies that target ras for inactivation in the treatment of cancer.
    MeSH term(s) Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Adenocarcinoma/radiotherapy ; Alleles ; Apoptosis/radiation effects ; Cell Division/genetics ; Cell Survival/radiation effects ; Clone Cells ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/radiotherapy ; Fibrosarcoma/genetics ; Fibrosarcoma/pathology ; Fibrosarcoma/radiotherapy ; Gene Expression Regulation, Neoplastic ; Genes, ras/physiology ; Humans ; Radiation Tolerance/genetics ; Tumor Cells, Cultured/physiology ; Tumor Cells, Cultured/radiation effects
    Language English
    Publishing date 2000-12-01
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
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    Uh III Zs.135/5: Show issues Location:
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  8. Book ; Online ; E-Book: Advances in Flavonoids for Human Health and Prevention of Diseases

    Sharma, Nisha / Saini, Deepika / Kesharwani, Rajesh K. / Gupta, Prakash Chandra / Keservani, Raj K.

    (AAP Advances in Nutraceuticals Series)

    2023  

    Abstract: Examines the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the development of diseases and how they manage of chronic pathological illnesses. Topics include natural food dyes as ... ...

    Series title AAP Advances in Nutraceuticals Series
    Abstract Examines the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the development of diseases and how they manage of chronic pathological illnesses. Topics include natural food dyes as nutraceuticals, flavonoid-rich diets to prevent chronic noncommunicable diseases.
    Keywords Flavonoids
    Subject code 615.3/21
    Language English
    Size 1 online resource (304 pages)
    Edition 1st ed.
    Publisher Apple Academic Press, Incorporated
    Publishing place Milton
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9781000841923 ; 9781774913451 ; 1000841928 ; 1774913453
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article: Response of two year old Pinus patula to N, P and K fertilization

    Singh, S.B / Prasad, K.G / Gupta, G.N / Maurya, G.S

    Indian forester. Jan 1986. v. 112 (1)

    1986  

    Keywords Pinus patula ; tree age ; urea ; superphosphate ; potassium fertilizers ; height ; girth
    Language English
    Dates of publication 1986-01
    Size p. 38-42.
    Document type Article
    Note Summary in Hindi.
    ZDB-ID 407898-6
    ISSN 0019-4816
    ISSN 0019-4816
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 2698: Show issues

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  10. Book: India /comp. Brijen K. Gupta, Datta S. Kharbas. With the assistence of Judith N. Kharbas, Arthur D. Lopatin

    Gupta, Brijen K / Kharbas, Datta S / Kharbas, Judith N / Lopatin, Arthur D

    (World bibliographical series ; 26)

    1984  

    Series title World bibliographical series ; 26
    Keywords Landeskunde ; Indien
    Language English
    Size XVIII, 264 S., Kt.
    Publisher Clio Press
    Publishing place Oxford u.a.
    Document type Book
    ISBN 0903450380 ; 9780903450386
    Database Former special subject collection: coastal and deep sea fishing

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