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  1. Book ; Online: La insulación del sistema educativo peruano

    Goyas, Ana / Salazar, Wilfredo / Contreras, Guadalupe / Flores-Poma, Irina / Cárdenas, Juan

    2023  

    Keywords Education ; niveles educativos ; realidad educativa ; sociedad peruana
    Language Spanish
    Size 1 electronic resource (101 pages)
    Publisher Instituto Universitario de Innovación Ciencia y Tecnología Inudi Perú
    Publishing place Puno
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030375395
    ISBN 9786125069719 ; 6125069710
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Securing the diagnosis of HRS-AKI: implications for current therapies.

    Mohanty, Arpan / Cárdenas, Andrés

    Expert review of gastroenterology & hepatology

    2024  Volume 17, Issue 12, Page(s) 1233–1239

    Abstract: Introduction: Hepatorenal syndrome (HRS)-acute kidney injury (HRS-AKI) is a specific type of kidney injury seen in patients with cirrhosis and ascites and is associated with high mortality and morbidity. It is characterized by rapid deterioration of ... ...

    Abstract Introduction: Hepatorenal syndrome (HRS)-acute kidney injury (HRS-AKI) is a specific type of kidney injury seen in patients with cirrhosis and ascites and is associated with high mortality and morbidity. It is characterized by rapid deterioration of renal function due to reduced renal blood flow secondary to portal hypertensive splanchnic and systemic vasodilation. Early diagnosis and treatment of HRS-AKI are associated with greater likelihood of improvement in renal function, lower need for dialysis, and better post-transplant outcomes.
    Areas covered: This review discusses the diagnostic criteria for HRS-AKI, which has undergone several key changes over the last decade, with an aim to secure an early diagnosis and aid swift treatment initiation. Additionally, this review outlines the current treatment paradigms for HRS-AKI.
    Expert opinion: In the last 20 years, there have been several advances in understanding the pathophysiology and natural course of HRS-AKI. These have led to critical changes in its definition and diagnostic algorithm. However, prognosis of HRS-AKI remains dismal with no significant improvement in HRS-AKI reversal or HRS-related mortality over this time. We discuss several gaps in the current understanding and management of HRS-AKI that will benefit from further research.
    MeSH term(s) Humans ; Hepatorenal Syndrome/diagnosis ; Liver Cirrhosis/complications ; Kidney ; Liver Transplantation ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy ; Vasoconstrictor Agents/therapeutic use
    Chemical Substances Vasoconstrictor Agents
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2481021-6
    ISSN 1747-4132 ; 1747-4124
    ISSN (online) 1747-4132
    ISSN 1747-4124
    DOI 10.1080/17474124.2023.2284189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6978: Show issues Location:
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  3. Article ; Online: Post-COVID-19 sequelae: an imbricate network between neuroinflammation and dysbiosis.

    Cárdenas-Hernández, Graciela A

    Cirugia y cirujanos

    2023  Volume 91, Issue 6, Page(s) 723–724

    Title translation Secuelas post-COVID-19: una imbricada red entre la neuroinflamación y la disbiosis.
    MeSH term(s) Humans ; COVID-19/complications ; Neuroinflammatory Diseases ; Dysbiosis/etiology
    Language English
    Publishing date 2023-12-14
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 730699-4
    ISSN 2444-054X ; 0009-7411
    ISSN (online) 2444-054X
    ISSN 0009-7411
    DOI 10.24875/CIRU.23000511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 797: Show issues Location:
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  4. Article: A practical approach to the endoscopic management of biliary strictures after liver transplantation.

    Bofill, Alex / Cárdenas, Andrés

    Annals of hepatology

    2023  Volume 29, Issue 2, Page(s) 101186

    Abstract: Biliary tract complications are an important cause of morbidity and mortality after liver transplantation (LT) occurring in 5% to 25% of patients. The most common biliary complication in LT recipients are strictures representing approximately half of ... ...

    Abstract Biliary tract complications are an important cause of morbidity and mortality after liver transplantation (LT) occurring in 5% to 25% of patients. The most common biliary complication in LT recipients are strictures representing approximately half of these biliary adverse events. Bile duct strictures can be divided into anastomotic biliary strictures (ABS) and non-anastomotic biliary strictures (NABS) depending on their location in the biliary tree, being ABS the most encountered type. Several risk factors identified in previous studies can predispose to the development of ABS and NABS, especially those related to surgical techniques and donor characteristics. Magnetic resonance cholangiopancreatography (MRCP) is the recommended noninvasive imaging test for detecting post-LT biliary strictures, given its high sensitivity and specificity. Once the diagnosis of a biliary stricture after LT has been made, endoscopic retrograde cholangiopancreatography (ERCP) is the preferred initial therapy with good short and long-term results. Biliary sphincterotomy plus balloon dilation (BD) with placement of multiple plastic stents (MPS) has been the classic endoscopic approach for treating ABS, although fully-covered metallic stents (FCSEMS) have emerged as an alternative thanks to shorter total duration of stenting and fewer endoscopic procedures compared to MPS. In this review, we provide a practical update on the management of biliary strictures after LT, focusing our attention on the available evidence in the endoscopic therapy.
    MeSH term(s) Humans ; Cholangiopancreatography, Endoscopic Retrograde ; Cholestasis/diagnostic imaging ; Cholestasis/etiology ; Cholestasis/surgery ; Constriction, Pathologic/etiology ; Constriction, Pathologic/surgery ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Retrospective Studies ; Stents ; Treatment Outcome
    Language English
    Publishing date 2023-11-28
    Publishing country Mexico
    Document type Review ; Editorial
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    DOI 10.1016/j.aohep.2023.101186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6221: Show issues Location:
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  5. Article ; Online: Terlipressin plus albumin in patients with HRS listed for liver transplant: Treat early and avoid RRT.

    Juanola, Adrià / Cárdenas, Andrés

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2023  Volume 30, Issue 4, Page(s) 335–336

    MeSH term(s) Humans ; Terlipressin/therapeutic use ; Liver Transplantation/adverse effects ; Vasoconstrictor Agents/therapeutic use ; Lypressin/therapeutic use ; Albumins/therapeutic use ; Hepatorenal Syndrome ; Treatment Outcome ; Liver Cirrhosis/drug therapy
    Chemical Substances Terlipressin (7Z5X49W53P) ; Vasoconstrictor Agents ; Lypressin (50-57-7) ; Albumins
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1097/LVT.0000000000000316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4702: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article: Fate of petroleum-based and plant-based teabags exposed to environmental soil conditions for one year.

    Mateos-Cárdenas, Alicia

    Frontiers in bioengineering and biotechnology

    2022  Volume 10, Page(s) 966685

    Abstract: Petroleum-based plastics are materials which have provided important industrial benefits from being lightweight and having low production costs. However, plastic pollution is pervasive and ubiquitous on all environments. This has led some industries to ... ...

    Abstract Petroleum-based plastics are materials which have provided important industrial benefits from being lightweight and having low production costs. However, plastic pollution is pervasive and ubiquitous on all environments. This has led some industries to rapidly introduce the so called 'bioplastics' into the market by switching the conventional ones for new plant-based alternatives with similar properties. However, little is known about the fate of such alternatives especially in the open environment. In this novel study, the degradation of teabags from eight different brands was investigated, five petroleum based (cellulose-PP blend) and three plant-based (cellulose, cellulose-PLA blend and PLA). The degradation was tested under real-environmental soil conditions over a 12-month period. Fourier Transform Infrared Spectroscopy (FTIR-ATR) and Scanning Electron Microscopy (SEM) techniques were used to examine the change in polymer makeup and surface degradation of teabags at 3 weeks, 3.5, 6 and 12 months. Teabag dry weight and any retrieved fragments were measured over time. Teabags that contained a plastic blended to cellulose were brittle or degraded into smaller fragments after 3 weeks in soil. Parallel to this, the cellulose layer also degraded in this short timeline. Petroleum-based teabags produced the highest numbers of PP fragments overtime and fragmented teabags were still found after 12 months. Plant-based teabags made of cellulose only or a blend of cellulose-PLA were absent from soil samples after 3.5 months, including no fragments. Contrary to this, teabags made of PLA which were marketed as completely biodegradable, persisted completely intact in soil throughout all time points. The novel results from this study provide a perspective on plastic degradation in terrestrial sources. Based on these findings, it can be recommended that teabags mostly made of cellulose or cellulose blended with a bioplastic present in a smaller ratio, are a better alternative to petroleum-based or pure PLA plastics, in terms of rapid environmental degradation. Further studies should focus on their ecotoxicity, additive presence, microbial degradation and life cycle in order to draw a full environmental assessment.
    Language English
    Publishing date 2022-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.966685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Secret to Success in Medical School: Reaching Out.

    Cardenas, Adam

    Academic medicine : journal of the Association of American Medical Colleges

    2022  Volume 98, Issue 7, Page(s) 757

    MeSH term(s) Humans ; Schools, Medical ; Achievement
    Language English
    Publishing date 2022-10-18
    Publishing country United States
    Document type Letter
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000005040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 112: Show issues Location:
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  8. Article ; Online: Prenatal Programming of Monocyte Chemotactic Protein-1 Signaling in Autism Susceptibility.

    Camacho-Morales, Alberto / Cárdenas-Tueme, Marcela

    Molecular neurobiology

    2024  

    Abstract: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that involves functional and structural defects in selective central nervous system (CNS) regions, harming the individual capability to process and respond to external stimuli, ... ...

    Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that involves functional and structural defects in selective central nervous system (CNS) regions, harming the individual capability to process and respond to external stimuli, including impaired verbal and non-verbal communications. Etiological causes of ASD have not been fully clarified; however, prenatal activation of the innate immune system by external stimuli might infiltrate peripheral immune cells into the fetal CNS and activate cytokine secretion by microglia and astrocytes. For instance, genomic and postmortem histological analysis has identified proinflammatory gene signatures, microglia-related expressed genes, and neuroinflammatory markers in the brain during ASD diagnosis. Active neuroinflammation might also occur during the developmental stage, promoting the establishment of a defective brain connectome and increasing susceptibility to ASD after birth. While still under investigation, we tested the hypothesis whether the monocyte chemoattractant protein-1 (MCP-1) signaling is prenatally programmed to favor peripheral immune cell infiltration and activate microglia into the fetal CNS, setting susceptibility to autism-like behavior. In this review, we will comprehensively provide the current understanding of the prenatal activation of MCP-1 signaling by external stimuli during the developmental stage as a new selective node to promote neuroinflammation, brain structural alterations, and behavioral defects associated to ASD diagnosis.
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-024-03940-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2411: Show issues Location:
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  9. Article ; Online: Trastornos del espectro autista y trastornos por déficit de atención con hiperactividad: desafíos en el diagnóstico y tratamiento.

    Velarde, Myriam / Cárdenas, Aland

    Medicina

    2022  Volume 82 Suppl 3, Page(s) 67–70

    Abstract: The coexistence of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) definitely poses new challenges, such as making an early diagnosis, considering that the former is usually diagnosed 2 years later in children with ADHD ...

    Title translation Autism spectrum disorder and attention-deficit/hyperactivity disorder: challenge in diagnosis and treatment.
    Abstract The coexistence of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) definitely poses new challenges, such as making an early diagnosis, considering that the former is usually diagnosed 2 years later in children with ADHD comorbid with autism compared to those with ASD alone; this is a problem at a personal, family and social level, since they must receive timely intervention. This coexistence raises questions about the efficacy of treatment in ADHD in people with autism, genetic, anatomical and functional concordances, among others; these are the challenges that are currently posed. In this review, we present some responses to the challenges posed by such coexistence, and we highlight some pending issues to be solved, being these of great importance for their better understanding and management. In all patients with ADHD or ASD, a coexistence between them should be sought. There are shared functional brain alterations in both disorders identified by functional brain magnetic resonance imaging; the treatment established for ADHD is also effective in this comorbidity.
    MeSH term(s) Attention Deficit Disorder with Hyperactivity/complications ; Attention Deficit Disorder with Hyperactivity/diagnosis ; Attention Deficit Disorder with Hyperactivity/therapy ; Autism Spectrum Disorder/complications ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/therapy ; Autistic Disorder ; Brain ; Child ; Comorbidity ; Humans
    Language Spanish
    Publishing date 2022-08-24
    Publishing country Argentina
    Document type Congress ; Review
    ZDB-ID 411586-7
    ISSN 1669-9106 ; 0025-7680 ; 0325-951X
    ISSN (online) 1669-9106
    ISSN 0025-7680 ; 0325-951X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 163: Show issues Location:
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  10. Article: Inteligencia artificial y tamizaje de la discapacidad visual relacionada con retinopatía diabética y edema macular.

    Castrillón-Lozano, Jorge A / Arango-Cárdenas, Dayhana / Marulanda-Márquez, Daniel E

    Gaceta medica de Mexico

    2024  

    Title translation Artificial intelligence and screening for visual impairment related to diabetic retinopathy and macular edema.
    Language Spanish
    Publishing date 2024-04-03
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.23000511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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