LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 56

Search options

  1. Book ; Online ; E-Book: Applications of nanotechnology in drug delivery and delivery

    Egbuna, Chukwuebuka / Găman, Mihnea-Alexandru / Jeevanandam, Jaison

    (Drug discovery update)

    2022  

    Author's details edited by Chukwuebuka Egbuna, Mihnea-Alexandru Găman and Jaison Jeevanandam
    Series title Drug discovery update
    Keywords Drug delivery systems ; Nanotechnology
    Subject code 615.6
    Language English
    Size 1 online resource (449 pages) :, illustrations
    Publisher Elsevier Radarweg
    Publishing place Amsterdam, Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-85931-3 ; 9780128244081 ; 978-0-323-85931-8 ; 0128244089
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online ; E-Book: Emerging nanomedicines for diabetes mellitus theranostics

    Danquah, Michael K. / Jeevanandam, Jaison

    (Micro and nano technologies series)

    2022  

    Author's details Michael K. Danquah, Jaison Jeevanandam
    Series title Micro and nano technologies series
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiii, 266 Seiten), Illustrationen, Diagramme
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021338193
    ISBN 978-0-323-85397-2 ; 9780323853965 ; 0-323-85397-8 ; 032385396X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Sustainable synthesis of bionanomaterials using non-native plant extracts for maintaining ecological balance: A computational bibliography analysis.

    Jeevanandam, Jaison / Rodrigues, João

    Journal of environmental management

    2024  Volume 358, Page(s) 120892

    Abstract: Biological approaches via biomolecular extracts of bacteria, fungi, or plants have recently been introduced as an alternative approach to synthesizing less or nontoxic nanomaterials, compared to conventional physical and chemical approaches. Among these ... ...

    Abstract Biological approaches via biomolecular extracts of bacteria, fungi, or plants have recently been introduced as an alternative approach to synthesizing less or nontoxic nanomaterials, compared to conventional physical and chemical approaches. Among these biological methods, plant-mediated approaches (phytosynthesis) are reported to be highly beneficial for large-scale, nontoxic nanomaterial synthesis. However, plant-mediated synthesis of nanomaterials using native plant extract can lead to bioprospecting issues and deforestation challenges. On the other hand, non-native or invasive plants are non-indigenous to a particular geographic location that can grow and spread rapidly, ultimately disrupting the local and endogenous plant communities or ecosystems. Thus, controlling or eradicating these non-native plants before they damage the ecosystem is necessary. Even though mechanical, chemical, and biological approaches are available to control non-native plants, all these methods possess certain limitations, such as environmental toxicity, disturbance in the nutrient cycle, and loss of genetic integrity. Therefore, non-native plants were recently proposed as a novel sustainable source of phytochemicals for preparing nanomaterials via green chemistry, mainly metallic nanoparticles, as an alternative to native, agriculture-based, or medicinal plants. This work aims to cover a literature gap on plant-mediated bionanomaterial synthesis with an overview and bibliography analysis of non-native plants via novel data mining and advanced visualization tools. In addition, the potential of non-native plants as a sustainable, green chemistry-based alternative for bionanomaterial preparation for maintaining ecological balance, the mechanism of formation via phytochemicals, and their possible applications to promote their control and spread were also discussed. The bibliography analysis revealed that only an average of 4 articles have been published in the last 10 years (2013-2023) on non-native/invasive plants for nanomaterial synthesis, which shows the significance of this article.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2024.120892
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7556: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Development of Janus Particles as Potential Drug Delivery Systems for Diabetes Treatment and Antimicrobial Applications.

    Tan, Kei Xian / Danquah, Michael K / Jeevanandam, Jaison / Barhoum, Ahmed

    Pharmaceutics

    2023  Volume 15, Issue 2

    Abstract: Janus particles have emerged as a novel and smart material that could improve pharmaceutical formulation, drug delivery, and theranostics. Janus particles have two distinct compartments that differ in functionality, physicochemical properties, and ... ...

    Abstract Janus particles have emerged as a novel and smart material that could improve pharmaceutical formulation, drug delivery, and theranostics. Janus particles have two distinct compartments that differ in functionality, physicochemical properties, and morphological characteristics, among other conventional particles. Recently, Janus particles have attracted considerable attention as effective particulate drug delivery systems as they can accommodate two opposing pharmaceutical agents that can be engineered at the molecular level to achieve better target affinity, lower drug dosage to achieve a therapeutic effect, and controlled drug release with improved pharmacokinetics and pharmacodynamics. This article discusses the development of Janus particles for tailored and improved delivery of pharmaceutical agents for diabetes treatment and antimicrobial applications. It provides an account of advances in the synthesis of Janus particles from various materials using different approaches. It appraises Janus particles as a promising particulate system with the potential to improve conventional delivery systems, providing a better loading capacity and targeting specificity whilst promoting multi-drugs loading and single-dose-drug administration.
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15020423
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Magnetic Nanoparticles for Protein Separation and Purification.

    Vedarethinam, Vadanasundari / Jeevanandam, Jaison / Acquah, Caleb / Danquah, Michael K

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2699, Page(s) 125–159

    Abstract: Proteins are essential for various functions such as brain activity and muscle contraction in humans. Even though food is a source of proteins, the bioavailability of proteins in most foods is usually limited due to matrix interaction with other ... ...

    Abstract Proteins are essential for various functions such as brain activity and muscle contraction in humans. Even though food is a source of proteins, the bioavailability of proteins in most foods is usually limited due to matrix interaction with other biomolecules. Thus, it is essential to extract these proteins and provide them as a nutraceutical supplement to maintain protein levels and avoid protein deficiency. Hence, protein purification and extraction from natural sources are highly significant in biomedical applications. Chromatography, crude mechanical disruption, use of extractive chemicals, and electrophoresis are some of the methods applied to isolate specific proteins. Even though these methods possess several advantages, they are unable to extract specific proteins with high purity. A suitable alternative is the use of nanoparticles, which can be beneficial in protein purification and extraction. Notably, magnetic iron and iron-based nanoparticles have been employed in protein extraction processes and can be reused via demagnetization due to their magnetic property, smaller size, morphology, high surface-to-volume ratio, and surface charge-mediated property. This chapter is a summary of various magnetic nanoparticles (MNPs) that can be used for the biomolecular separation of proteins.
    MeSH term(s) Humans ; Magnetite Nanoparticles ; Biological Availability ; Chromatography, Affinity ; Dietary Supplements ; Iron
    Chemical Substances Magnetite Nanoparticles ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-08-28
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3362-5_8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles.

    Jeevanandam, Jaison / Tan, Kei Xian / Rodrigues, João / Danquah, Michael K

    Pharmaceutics

    2023  Volume 15, Issue 6

    Abstract: Nanosized Janus and dendrimer particles have emerged as promising nanocarriers for the target-specific delivery and improved bioavailability of pharmaceuticals. Janus particles, with two distinct regions exhibiting different physical and chemical ... ...

    Abstract Nanosized Janus and dendrimer particles have emerged as promising nanocarriers for the target-specific delivery and improved bioavailability of pharmaceuticals. Janus particles, with two distinct regions exhibiting different physical and chemical properties, provide a unique platform for the simultaneous delivery of multiple drugs or tissue-specific targeting. Conversely, dendrimers are branched, nanoscale polymers with well-defined surface functionalities that can be designed for improved drug targeting and release. Both Janus particles and dendrimers have demonstrated their potential to improve the solubility and stability of poorly water-soluble drugs, increase the intracellular uptake of drugs, and reduce their toxicity by controlling the release rate. The surface functionalities of these nanocarriers can be tailored to specific targets, such as overexpressed receptors on cancer cells, leading to enhanced drug efficacy The design of these nanocarriers can be optimized by tuning the size, shape, and surface functionalities, among other parameters. The incorporation of Janus and dendrimer particles into composite materials to create hybrid systems for enhancing drug delivery, leveraging the unique properties and functionalities of both materials, can offer promising outcomes. Nanosized Janus and dendrimer particles hold great promise for the delivery and improved bioavailability of pharmaceuticals. Further research is required to optimize these nanocarriers and bring them to the clinical setting to treat various diseases. This article discusses various nanosized Janus and dendrimer particles for target-specific delivery and bioavailability of pharmaceuticals. In addition, the development of Janus-dendrimer hybrid nanoparticles to address some limitations of standalone nanosized Janus and dendrimer particles is discussed.
    Language English
    Publishing date 2023-05-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15061614
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Enhanced alpha-amylase inhibition activity of amine-terminated PAMAM dendrimer stabilized pure copper-doped magnesium oxide nanoparticles.

    Jeevanandam, Jaison / Gonçalves, Mara / Castro, Rita / Gallo, Juan / Bañobre-López, Manuel / Rodrigues, João

    Biomaterials advances

    2023  Volume 153, Page(s) 213535

    Abstract: The present work aims to prepare copper-doped MgO nanoparticles via a sol-gel approach and study their antidiabetic alpha-amylase inhibition activity with undoped MgO nanoparticles. The ability of G5 amine-terminated polyamidoamine (PAMAM) dendrimer for ... ...

    Abstract The present work aims to prepare copper-doped MgO nanoparticles via a sol-gel approach and study their antidiabetic alpha-amylase inhibition activity with undoped MgO nanoparticles. The ability of G5 amine-terminated polyamidoamine (PAMAM) dendrimer for the controlled release of copper-doped MgO nanoparticles to exhibit alpha-amylase inhibition activity was also evaluated. The synthesis of MgO nanoparticles via sol-gel approach and optimization of calcination temperature and time has led to the formation of nanoparticles with different shapes (spherical, hexagonal, and rod-shaped) and a polydispersity in size ranging from 10 to 100 nm with periclase crystalline phase. The presence of copper ions in the MgO nanoparticles has altered their crystallite size, eventually modifying their size, morphology, and surface charge. The efficiency of dendrimer to stabilize spherical copper-doped MgO nanoparticles (ca. 30 %) is higher than in other samples, which was confirmed by UV-Visible, DLS, FTIR, and TEM analysis. The amylase inhibition assay emphasized that the dendrimer nanoparticles stabilization has led to the prolonged enzyme inhibition ability of MgO and copper-doped MgO nanoparticles for up to 24 h.
    MeSH term(s) Dendrimers/chemistry ; Magnesium Oxide/chemistry ; Magnesium ; Copper ; Nanoparticles/chemistry ; Polyamines/chemistry ; alpha-Amylases
    Chemical Substances PAMAM Starburst ; Dendrimers ; Poly(amidoamine) ; Magnesium Oxide (3A3U0GI71G) ; Magnesium (I38ZP9992A) ; cuprous oxide (T8BEA5064F) ; Copper (789U1901C5) ; Polyamines ; alpha-Amylases (EC 3.2.1.1)
    Language English
    Publishing date 2023-06-21
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-9508
    ISSN (online) 2772-9508
    DOI 10.1016/j.bioadv.2023.213535
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Cytotoxicity and insulin resistance reversal ability of biofunctional phytosynthesized MgO nanoparticles.

    Jeevanandam, Jaison / Chan, Yen San / Danquah, Michael K

    3 Biotech

    2020  Volume 10, Issue 11, Page(s) 489

    Abstract: The present study investigates the cytotoxicity of hexagonal MgO nanoparticles synthesized ... ...

    Abstract The present study investigates the cytotoxicity of hexagonal MgO nanoparticles synthesized via
    Language English
    Publishing date 2020-10-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-020-02480-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Aptamer-Mediated Antiviral Approaches for SARS-CoV-2.

    Tan, Kei Xian / Jeevanandam, Jaison / Rodrigues, João / Danquah, Michael K

    Frontiers in bioscience (Landmark edition)

    2022  Volume 27, Issue 11, Page(s) 306

    Abstract: 2020 and 2021 were disastrous years across the world, with the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which continues to be a top global health issue. There are still many countries and regions ... ...

    Abstract 2020 and 2021 were disastrous years across the world, with the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which continues to be a top global health issue. There are still many countries and regions struggling to fight coronavirus disease 2019 (COVID-19), and, with the emergence of the various variants of the virus, we are still far from considering this global pandemic over. In addition to having good diagnostic tools and a variety of vaccines with high efficacy, it is of utmost importance to develop effective antiviral drugs or therapies to battle COVID-19. Aptamers known as the next-generation targeting elements can offer promising opportunities in developing antiviral drugs against SARS-CoV-2. This is owing to their high specificity and affinity, making them ideal for targeting ligands and neutralizers to impede both, viral entry and replication or even further enhance the anti-infection effects in the infected host cells. Also, aptamers are extremely attractive as they can be rapidly synthesized and scalable with a lower production cost. This work provides in-depth discussions on the potential of aptamers in therapeutic applications, their mode of action, and current progress on the use of aptamer-based therapies against SARS-CoV-2 and other viruses. The article also discusses the limitations associated with aptamer-based SARS-CoV-2-antiviral therapy with several proposed ideas to resolve them. Lastly, theranostic applications of aptamer nanoformulated dendrimers against viral infections are discussed.
    Language English
    Publishing date 2022-11-23
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 2768-6698
    ISSN (online) 2768-6698
    ISSN 2768-6698
    DOI 10.31083/j.fbl2711306
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Aptamer-Mediated Antiviral Approaches for SARS-CoV-2

    Kei Xian Tan / Jaison Jeevanandam / João Rodrigues / Michael K. Danquah

    Frontiers in Bioscience-Landmark, Vol 27, Iss 11, p

    2022  Volume 306

    Abstract: 2020 and 2021 were disastrous years across the world, with the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which continues to be a top global health issue. There are still many countries and regions ... ...

    Abstract 2020 and 2021 were disastrous years across the world, with the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which continues to be a top global health issue. There are still many countries and regions struggling to fight coronavirus disease 2019 (COVID-19), and, with the emergence of the various variants of the virus, we are still far from considering this global pandemic over. In addition to having good diagnostic tools and a variety of vaccines with high efficacy, it is of utmost importance to develop effective antiviral drugs or therapies to battle COVID-19. Aptamers known as the next-generation targeting elements can offer promising opportunities in developing antiviral drugs against SARS-CoV-2. This is owing to their high specificity and affinity, making them ideal for targeting ligands and neutralizers to impede both, viral entry and replication or even further enhance the anti-infection effects in the infected host cells. Also, aptamers are extremely attractive as they can be rapidly synthesized and scalable with a lower production cost. This work provides in-depth discussions on the potential of aptamers in therapeutic applications, their mode of action, and current progress on the use of aptamer-based therapies against SARS-CoV-2 and other viruses. The article also discusses the limitations associated with aptamer-based SARS-CoV-2-antiviral therapy with several proposed ideas to resolve them. Lastly, theranostic applications of aptamer nanoformulated dendrimers against viral infections are discussed.
    Keywords aptamers ; antiviral drug ; sars-cov-2 ; viral infection ; dendrimer ; nanoformulation ; Biochemistry ; QD415-436 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher IMR Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top