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  1. Article: Utilization of biomarkers for the prognostic prediction of cardiac arrest survivors using a multi-modal approach.

    Kang, Changshin / You, Yeonho / Park, Jung Soo / Park, Byeong Kwon / Lee, Jae Kwang / Lee, Byung Kook

    World journal of emergency medicine

    2024  Volume 15, Issue 2, Page(s) 131–134

    Language English
    Publishing date 2024-02-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 2753264-1
    ISSN 1920-8642
    ISSN 1920-8642
    DOI 10.5847/wjem.j.1920-8642.2024.029
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  2. Article: Human Cytomegalovirus Host Interactions: EGFR and Host Cell Signaling Is a Point of Convergence Between Viral Infection and Functional Changes in Infected Cells.

    Lee, Byeong-Jae / Min, Chan-Ki / Hancock, Meaghan / Streblow, Daniel N / Caposio, Patrizia / Goodrum, Felicia D / Yurochko, Andrew D

    Frontiers in microbiology

    2021  Volume 12, Page(s) 660901

    Abstract: Viruses have evolved diverse strategies to manipulate cellular signaling pathways in order to promote infection and/or persistence. Human cytomegalovirus (HCMV) possesses a number of unique properties that allow the virus to alter cellular events ... ...

    Abstract Viruses have evolved diverse strategies to manipulate cellular signaling pathways in order to promote infection and/or persistence. Human cytomegalovirus (HCMV) possesses a number of unique properties that allow the virus to alter cellular events required for infection of a diverse array of host cell types and long-term persistence. Of specific importance is infection of bone marrow derived and myeloid lineage cells, such as peripheral blood monocytes and CD34
    Language English
    Publishing date 2021-05-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.660901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Co-synthesis and Electrochemical Investigation of the Nitrogen-Doped Carbon Layer with Metallic Nano Beads on the SiO

    Lee, Byeong Gwon / Lee, Seung Hun / Do, Vandung / Lee, Jae Woo / Choi, Sun Ho / Kim, Woong / Cho, Won Il

    ACS applied materials & interfaces

    2024  Volume 16, Issue 8, Page(s) 10042–10051

    Abstract: The high theoretical capacity (∼2000 mAh ... ...

    Abstract The high theoretical capacity (∼2000 mAh g
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c16105
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  4. Article: Novel microbiota

    Yu, Seung Yeob / Oh, Byeong Seob / Ryu, Seoung Woo / Bak, Jeong Eun / Heo, Eun Seo / Moon, Jeong Chan / Jeong, Jae-Ho / Lee, Ju Huck

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1342098

    Abstract: A novel Gram-negative, obligate anaerobe, non-motile, flagella-lacking, catalase- and oxidase-negative, coccobacilli-shaped bacterial strain designated ... ...

    Abstract A novel Gram-negative, obligate anaerobe, non-motile, flagella-lacking, catalase- and oxidase-negative, coccobacilli-shaped bacterial strain designated AGMB02718
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1342098
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  5. Article: Green discoloration of urine after propofol infusion.

    Lee, Jung-Sam / Jang, Hyun-Soo / Park, Byeong-Jae

    Korean journal of anesthesiology

    2013  Volume 65, Issue 2, Page(s) 177–179

    Language English
    Publishing date 2013-08-27
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2557340-8
    ISSN 2005-7563 ; 2005-6419
    ISSN (online) 2005-7563
    ISSN 2005-6419
    DOI 10.4097/kjae.2013.65.2.177
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  6. Article ; Online: The Differentiation of Human Cytomegalovirus Infected-Monocytes Is Required for Viral Replication.

    Min, Chan-Ki / Shakya, Akhalesh K / Lee, Byeong-Jae / Streblow, Daniel N / Caposio, Patrizia / Yurochko, Andrew D

    Frontiers in cellular and infection microbiology

    2020  Volume 10, Page(s) 368

    Abstract: Viral dissemination is a key mechanism responsible for persistence and disease following human cytomegalovirus (HCMV) infection. Monocytes play a pivotal role in viral dissemination to organ tissue during primary infection and following reactivation from ...

    Abstract Viral dissemination is a key mechanism responsible for persistence and disease following human cytomegalovirus (HCMV) infection. Monocytes play a pivotal role in viral dissemination to organ tissue during primary infection and following reactivation from latency. For example, during primary infection, infected monocytes migrate into tissues and differentiate into macrophages, which then become a source of viral replication. In addition, because differentiated macrophages can survive for months to years, they provide a potential persistent infection source in various organ systems. We broadly note that there are three phases to infection and differentiation of HCMV-infected monocytes: (1) Virus enters and traffics to the nucleus through a virus receptor ligand engagement event that activates a unique signalsome that initiates the monocyte-to-macrophage differentiation process. (2) Following initial infection, HCMV undergoes a "quiescence-like state" in monocytes lasting for several weeks and promotes monocyte differentiation into macrophages. While, the initial event is triggered by the receptor-ligand engagement, the long-term cellular activation is maintained by chronic viral-mediated signaling events. (3) Once HCMV infected monocytes differentiate into macrophages, the expression of immediate early viral (IE) genes is detectable, followed by viral replication and long term infectious viral particles release. Herein, we review the detailed mechanisms of each phase during infection and differentiation into macrophages and discuss the biological significance of the differentiation of monocytes in the pathogenesis of HCMV.
    MeSH term(s) Cell Differentiation ; Cells, Cultured ; Cytomegalovirus ; Cytomegalovirus Infections ; Humans ; Monocytes ; Virus Replication
    Language English
    Publishing date 2020-07-31
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2020.00368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Exercise-induced desaturation during a six-minute walk test is associated with poor clinical outcomes in patients with pulmonary arterial hypertension.

    Choi, Jung Hyun / Shin, Myung-Jun / Lee, Byeong-Ju / Park, Jae-Hyeong

    Clinical hypertension

    2023  Volume 29, Issue 1, Page(s) 33

    Abstract: Background: The six-minute walk test (6MWT) is an established exercise test for patients with pulmonary arterial hypertension (PAH), affording insight into both exercise intolerance and overall prognosis. Despite the widespread application of the 6MWT, ... ...

    Abstract Background: The six-minute walk test (6MWT) is an established exercise test for patients with pulmonary arterial hypertension (PAH), affording insight into both exercise intolerance and overall prognosis. Despite the widespread application of the 6MWT, the prognostic implications of exercise-induced desaturation (EID) during this test has been inadequately studied in PAH patients. Thus, we evaluated the occurrence of EID and its prognostic significance in PAH patients.
    Methods: We analyzed PAH patients in a single-center cohort from April 2016 to March 2021. EID was defined as a reduction in oxygen saturation exceeding 4% from the baseline or to below 90% at any point during the test.
    Results: We analyzed 20 PAH patients in this cohort, primarily consisting of 16 females with an average age of 48.4 ± 13.3 years. Among them, ten exhibited EID. Baseline characteristics, echocardiographic data and right heart catheterization data were similar between the two groups. However, total distance (354.3 ± 124.4 m vs. 485.4 ± 41.4 m, P = 0.019) and peak oxygen uptake (12.9 ± 3.2 mL/kg⋅min vs. 16.4 ± 3.6 mL/kg⋅min, P = 0.019) were significantly lower in the EID group. During the total follow-up duration of 51.9 ± 25.7 months, 17 patients had at least one adverse clinical event (2 deaths, 1 lung transplantation, and 13 hospital admissions). The presence of EID was associated with poor clinical outcome (hazard ratio = 6.099, 95% confidence interval = 1.783-20.869, P = 0.004).
    Conclusions: During the 6MWT, EID was observed in a half of PAH patients and emerged as a significant prognostic marker for adverse clinical events.
    Language English
    Publishing date 2023-12-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2806585-2
    ISSN 2056-5909
    ISSN 2056-5909
    DOI 10.1186/s40885-023-00256-3
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  8. Article: Air pollution exposure and cardiovascular disease.

    Lee, Byeong-Jae / Kim, Bumseok / Lee, Kyuhong

    Toxicological research

    2014  Volume 30, Issue 2, Page(s) 71–75

    Abstract: Ambient air pollution (AAP) and particulate matters (PM) have been closely associated with adverse health effects such as respiratory disease and cardiovascular diseases. Previous studies have examined the adverse health effects associated with short- ... ...

    Abstract Ambient air pollution (AAP) and particulate matters (PM) have been closely associated with adverse health effects such as respiratory disease and cardiovascular diseases. Previous studies have examined the adverse health effects associated with short- and long-term exposure to AAP and outdoor PM on respiratory disease. However, the effect of PM size (PM2.5 and PM10) on cardiovascular disease has not been well studied. Thus, it remains unclear how the size of the inhalable particles (coarse, fine, or ultrafine) affects mortality and morbidity. Airborne PM concentrations are commonly used for ambient air quality management worldwide, owing to the known effects on cardiorespiratory health. In this article, we assess the relationship between cardiovascular diseases and PM, with a particular focus on PM size. We discuss the association of PM2.5 and PM10, nitrogen dioxide (NO2), and elemental carbon with mortality and morbidity due to cardiovascular diseases, stroke, and altered blood pressure, based on epidemiological studies. In addition, we provide evidence that the adverse health effects of AAP and PM are more pronounced among the elderly, children, and people with preexisting cardiovascular and respiratory conditions. Finally, we critically summarize the literature pertaining to cardiovascular diseases, including atherosclerosis and stroke, and introduce potential studies to better understand the health significance of AAP and PM on cardiovascular disease.
    Language English
    Publishing date 2014-07-01
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2727978-9
    ISSN 2234-2753 ; 1976-8257
    ISSN (online) 2234-2753
    ISSN 1976-8257
    DOI 10.5487/TR.2014.30.2.071
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  9. Article ; Online: Enhancing Post-Surgical Rehabilitation Outcomes in Patients with Chronic Ankle Instability: Impact of Subtalar Joint Axis Balance Exercises Following Arthroscopic Modified Broström Operation.

    Park, Ji-Myeong / Han, Sang-Ho / Cho, Byeong-Chae / Lee, Se-Min / Shin, Mal-Soon / Yu, Jae-Ho / Kim, Ho-Jin / Noh, Hyun-Dong / Cho, Min-Suk / Kim, Myung-Ki

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 2

    Abstract: Background and Objectives: ...

    Abstract Background and Objectives:
    MeSH term(s) Humans ; Ankle ; Subtalar Joint/surgery ; Ankle Joint/surgery ; Lateral Ligament, Ankle/surgery ; Treatment Outcome ; Joint Instability/surgery
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60020328
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Delineation of three-dimensional tumor margins based on normalized absolute difference mapping via volumetric optical coherence tomography.

    Park, Jae-Sung / Yoon, Taeil / Park, Soon A / Lee, Byeong Ha / Jeun, Sin-Soo / Eom, Tae Joong

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7984

    Abstract: The extent of surgical resection is an important prognostic factor in the treatment of patients with glioblastoma. Optical coherence tomography (OCT) imaging is one of the adjunctive methods available to achieve the maximal surgical resection. In this ... ...

    Abstract The extent of surgical resection is an important prognostic factor in the treatment of patients with glioblastoma. Optical coherence tomography (OCT) imaging is one of the adjunctive methods available to achieve the maximal surgical resection. In this study, the tumor margins were visualized with the OCT image obtained from a murine glioma model. A commercialized human glioblastoma cell line (U-87) was employed to develop the orthotopic murine glioma model. A swept-source OCT (SS-OCT) system of 1300 nm was used for three-dimensional imaging. Based on the OCT intensity signal, which was obtained via accumulation of each A-scan data, an en-face optical attenuation coefficient (OAC) map was drawn. Due to the limited working distance of the focused beam, OAC values decrease with depth, and using the OAC difference in the superficial area was chosen to outline the tumor boundary, presenting a challenge in analyzing the tumor margin along the depth direction. To overcome this and enable three-dimensional tumor margin detection, we converted the en-face OAC map into an en-face difference map with x- and y-directions and computed the normalized absolute difference (NAD) at each depth to construct a volumetric NAD map, which was compared with the corresponding H&E-stained image. The proposed method successfully revealed the tumor margin along the peripheral boundaries as well as the margin depth. We believe this method can serve as a useful adjunct in glioma surgery, with further studies necessary for real-world practical applications.
    MeSH term(s) Humans ; Animals ; Mice ; Glioblastoma/diagnostic imaging ; Tomography, Optical Coherence/methods ; NAD ; Glioma/pathology ; Imaging, Three-Dimensional
    Chemical Substances NAD (0U46U6E8UK)
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56239-3
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