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  1. AU=Walker Scott C
  2. AU="Sheridan, Katherine"
  3. AU="Brown, Sharlie B"
  4. AU=Walker Kathleen
  5. AU="Miller, Donald G"
  6. AU="Sendino, O"
  7. AU="Rao, Arya"
  8. AU="Wong, Gary K W"

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  1. Artikel ; Online: H.O.P.E. grows: An academic-public health partnership to reimagine public health services and increase mental health access among socially vulnerable populations.

    Scott, Victoria C / Tolley, Annalise J / Langhinrichsen-Rohling, Jennifer / Walker, Kayla / Greene, Tamikia

    Health services research

    2023  Band 59 Suppl 1, Seite(n) e14253

    Abstract: Objective: To illustrate the process of developing and sustaining an academic-public health partnership for behavioral health integration through an expansion of the Aligning Systems for Health (ASfH) framework.: Study setting: Practice-informed ... ...

    Abstract Objective: To illustrate the process of developing and sustaining an academic-public health partnership for behavioral health integration through an expansion of the Aligning Systems for Health (ASfH) framework.
    Study setting: Practice-informed primary data (2017-2023) from the Holistic Opportunity Program for Everyone (HOPE) Initiative based in Charlotte, NC.
    Study design: The unit of analysis in this descriptive case study is inter-organizational, specifically focusing on an academic-public health relationship. We illustrate the partnership process across the ASfH four core areas, including key challenges and insights.
    Data collection: Utilized a Critical Moments Reflection methodology and review of HOPE program data.
    Principal findings: (1) Formal partnership structures and processes are essential to monitoring the four ASfH core components for on-going system alignment. (2) Aligning systems for health principally involves two ecologies: (i) the health program and (ii) the partnership. The vitality and sustainability of both ecologies require continuous attention and resource investment. (3) Relationships rest at the heart of aligning systems. (4) With comparative advantages in research methods, the academic sector is especially poised to collaborate with healthcare systems and human service organizations to study, develop, implement, and scale evidence-based health interventions.
    Conclusions: The academic sector shares overlapping purposes with the public health, healthcare, and social services sectors while providing complementary value. It is a critical sectoral partner in advancing population health and health equity.
    Mesh-Begriff(e) Humans ; Public Health ; Vulnerable Populations ; Mental Health ; Delivery of Health Care ; Health Services
    Sprache Englisch
    Erscheinungsdatum 2023-11-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 410435-3
    ISSN 1475-6773 ; 0017-9124
    ISSN (online) 1475-6773
    ISSN 0017-9124
    DOI 10.1111/1475-6773.14253
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Improving voluntary engagement for posttraumatic stress disorder treatment among active-duty service members using motivational enhancement therapy.

    Walker, Denise D / Walton, Thomas O / Jaffe, Anna E / Graupensperger, Scott / Rhew, Isaac C / Kaysen, Debra

    Psychological trauma : theory, research, practice and policy

    2023  

    Abstract: ... for interventions facilitating treatment uptake. (PsycInfo Database Record (c) 2023 APA, all rights reserved). ...

    Abstract Objective: Posttraumatic stress disorder (PTSD) prevalence in the military is high and effective treatments are underutilized. Motivational enhancement therapy (MET) "check-ups" are brief interventions to elicit treatment uptake for those who are nontreatment seeking. The aim of the current study was to test the efficacy of a novel MET intervention designed to promote treatment engagement among active-duty U.S. military personnel with untreated PTSD.
    Method: One hundred and sixty-one active-duty service members who met the criteria for PTSD were randomized to MET or treatment as usual (TAU, treatment resource and referral). MET participants (
    Results: Mixed effect model results indicated treatment uptake significantly increased over time but there were no significant differences between conditions or interactions. PTSD symptom severity significantly decreased for both conditions. There was also a significant three-way interaction with baseline readiness-to-change confidence. Those low in baseline readiness-to-change saw more favorable effects of MET (relative to TAU) at 6-month follow-up.
    Conclusions: Results suggest both MET and high-quality referral options have promise as a means of increasing evidence-based treatment uptake and decreasing PTSD for service members with PTSD. MET may be particularly useful for individuals with low confidence in their ability to address PTSD. Given the individual and societal costs of PTSD, there is a need for interventions facilitating treatment uptake. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    Sprache Englisch
    Erscheinungsdatum 2023-10-12
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2497028-1
    ISSN 1942-969X ; 1942-9681
    ISSN (online) 1942-969X
    ISSN 1942-9681
    DOI 10.1037/tra0001562
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The Chemistry of Green and Roasted Coffee by Selectable 1D/2D Gas Chromatography Mass Spectrometry with Spectral Deconvolution.

    Frost, Scott C / Walker, Paige / Orians, Colin M / Robbat, Albert

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 16

    Abstract: Gas chromatography/mass spectrometry (GC/MS) is a long-standing technique for the analysis of volatile organic compounds (VOCs). When coupled with the Ion Analytics software, GC/MS provides unmatched selectivity in the analysis of complex mixtures and it ...

    Abstract Gas chromatography/mass spectrometry (GC/MS) is a long-standing technique for the analysis of volatile organic compounds (VOCs). When coupled with the Ion Analytics software, GC/MS provides unmatched selectivity in the analysis of complex mixtures and it reduces the reliance on high-resolution chromatography to obtain clean mass spectra. Here, we present an application of spectral deconvolution, with mass spectral subtraction, to identify a wide array of VOCs in green and roasted coffees. Automated sequential, two-dimensional GC-GC/MS of a roasted coffee sample produced the retention index and spectrum of 750 compounds. These initial analytes served as targets for subsequent coffee analysis by GC/MS. The workflow resulted in the quantitation of 511 compounds detected in two different green and roasted coffees. Of these, over 100 compounds serve as candidate differentiators of coffee quality, AAA vs. AA, as designated by the Coopedota cooperative in Costa Rica. Of these, 72 compounds survive the roasting process and can be used to discriminate green coffee quality after roasting.
    Mesh-Begriff(e) Coffee/chemistry ; Gas Chromatography-Mass Spectrometry/methods ; Mass Spectrometry ; Volatile Organic Compounds/analysis
    Chemische Substanzen Coffee ; Volatile Organic Compounds
    Sprache Englisch
    Erscheinungsdatum 2022-08-21
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27165328
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Septic Arthritis: Diagnosis and Treatment.

    Earwood, John Scott / Walker, Tyler R / Sue, Gregory J C

    American family physician

    2021  Band 104, Heft 6, Seite(n) 589–597

    Abstract: ... Physical examination findings and serum markers, including erythrocyte sedimentation rate and C-reactive protein, are ...

    Abstract Septic arthritis must be considered and promptly diagnosed in any patient presenting with acute atraumatic joint pain, swelling, and fever. Risk factors for septic arthritis include age older than 80 years, diabetes mellitus, rheumatoid arthritis, recent joint surgery, hip or knee prosthesis, skin infection, and immunosuppressive medication use. A delay in diagnosis and treatment can result in permanent morbidity and mortality. Physical examination findings and serum markers, including erythrocyte sedimentation rate and C-reactive protein, are helpful in the diagnosis but are nonspecific. Synovial fluid studies are required to confirm the diagnosis. History and Gram stain aid in determining initial antibiotic selection. Staphylococcus aureus is the most common pathogen isolated in septic arthritis; however, other bacteria, viruses, fungi, and mycobacterium can cause the disease. After synovial fluid has been obtained, empiric antibiotic therapy should be initiated if there is clinical concern for septic arthritis. Oral antibiotics can be given in most cases because they are not inferior to intravenous therapy. Total duration of therapy ranges from two to six weeks; however, certain infections require longer courses. Consideration for microorganisms such as Neisseria gonorrhoeae, Borrelia burgdorferi, and fungal infections should be based on history findings and laboratory results.
    Mesh-Begriff(e) Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Arthralgia/etiology ; Arthritis, Infectious/complications ; Arthritis, Infectious/diagnosis ; Arthritis, Infectious/therapy ; Blood Sedimentation/methods ; Blood Sedimentation/statistics & numerical data ; Borrelia burgdorferi/drug effects ; Borrelia burgdorferi/pathogenicity ; Fever/etiology ; Humans ; Neisseria gonorrhoeae/drug effects ; Neisseria gonorrhoeae/pathogenicity ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/pathogenicity ; Synovial Fluid/microbiology
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2021-12-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 412694-4
    ISSN 1532-0650 ; 0002-838X ; 0572-3612
    ISSN (online) 1532-0650
    ISSN 0002-838X ; 0572-3612
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Chemistry of Green and Roasted Coffee by Selectable 1D/2D Gas Chromatography Mass Spectrometry with Spectral Deconvolution

    Scott C. Frost / Paige Walker / Colin M. Orians / Albert Robbat

    Molecules, Vol 27, Iss 16, p

    2022  Band 5328

    Abstract: Gas chromatography/mass spectrometry (GC/MS) is a long-standing technique for the analysis of volatile organic compounds (VOCs). When coupled with the Ion Analytics software, GC/MS provides unmatched selectivity in the analysis of complex mixtures and it ...

    Abstract Gas chromatography/mass spectrometry (GC/MS) is a long-standing technique for the analysis of volatile organic compounds (VOCs). When coupled with the Ion Analytics software, GC/MS provides unmatched selectivity in the analysis of complex mixtures and it reduces the reliance on high-resolution chromatography to obtain clean mass spectra. Here, we present an application of spectral deconvolution, with mass spectral subtraction, to identify a wide array of VOCs in green and roasted coffees. Automated sequential, two-dimensional GC-GC/MS of a roasted coffee sample produced the retention index and spectrum of 750 compounds. These initial analytes served as targets for subsequent coffee analysis by GC/MS. The workflow resulted in the quantitation of 511 compounds detected in two different green and roasted coffees. Of these, over 100 compounds serve as candidate differentiators of coffee quality, AAA vs. AA, as designated by the Coopedota cooperative in Costa Rica. Of these, 72 compounds survive the roasting process and can be used to discriminate green coffee quality after roasting.
    Schlagwörter GC/MS ; 2D–GC/MS ; deconvolution ; coffee ; green coffee ; coffee quality ; Organic chemistry ; QD241-441
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsdatum 2022-08-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Serological and growth rate responses to the use of chicken Newcastle disease vaccines in pigeons.

    Scott, P C / Wilson, T B / Walker, C

    Australian veterinary journal

    2019  Band 91, Heft 12, Seite(n) 525–530

    Abstract: Objective: In the face of an outbreak of pigeon paramyxovirus (PPMV), a vaccination response study was undertaken to determine if pigeons in Australia would produce a serological response similar to that considered protective in chickens.: Design: A ... ...

    Abstract Objective: In the face of an outbreak of pigeon paramyxovirus (PPMV), a vaccination response study was undertaken to determine if pigeons in Australia would produce a serological response similar to that considered protective in chickens.
    Design: A vaccination study evaluated serological response and safety criteria in groups of 20 pigeons.
    Methods: One group served as unvaccinated controls; one group was vaccinated with a live V4 strain of Newcastle disease virus (NDV) and subsequently revaccinated 28 days later with an inactivated La Sota strain vaccine; the third group was vaccinated twice with the inactivated La Sota strain vaccine 28 days apart. Serum was collected from the birds for serology 28, 56, 120 and 196 days after each treatment. Safety of the vaccines was determined using observation of the birds and body weight change. Serology was performed using three variations of the haemagglutination inhibition (HI) test, including chicken red blood cells (RBC) with either V4 NDV or PPMV as the antigen and pigeon RBC with V4 NDV as the antigen. A commercial NDV ELISA test was also used.
    Results: At 28 days after the second vaccination, the geometric mean titres were 6.8 and 7.3 for the live/inactivated vaccine regimen and the inactivated/inactivated regimen, respectively. The serological response of birds vaccinated with the inactivated/inactivated regimen was significantly greater than that of the controls for all of the serological tests used.
    Conclusion: Vaccination of pigeons with two doses of chicken NDV vaccine 28 days apart was safe and resulted in antibody levels considered protective for NDV in chickens.
    Sprache Englisch
    Erscheinungsdatum 2019-04-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 41542-x
    ISSN 1751-0813 ; 0005-0423
    ISSN (online) 1751-0813
    ISSN 0005-0423
    DOI 10.1111/avj.12127
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: In Response.

    Odegard, Kirsten C / Walker, Scott G

    Anesthesia and analgesia

    2017  Band 125, Heft 3, Seite(n) 1078–1079

    Sprache Englisch
    Erscheinungsdatum 2017-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000002284
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Art therapy masks reflect emotional changes in military personnel with PTSS.

    Estrada Gonzalez, V / Meletaki, V / Walker, M / Payano Sosa, J / Stamper, A / Srikanchana, R / King, J L / Scott, K / Cardillo, E R / Rhodes, C Sours / Christensen, A P / Darda, K M / Workman, C I / Chatterjee, A

    Scientific reports

    2024  Band 14, Heft 1, Seite(n) 7192

    Abstract: Among disabling post-traumatic stress symptoms (PTSS) are irritability, aggressive behavior, distressing memories and general impaired cognition and negative mood. Art therapy interventions, including mask-making, can potentially alleviate these symptoms. ...

    Abstract Among disabling post-traumatic stress symptoms (PTSS) are irritability, aggressive behavior, distressing memories and general impaired cognition and negative mood. Art therapy interventions, including mask-making, can potentially alleviate these symptoms. We tested the hypothesis that art conveys emotions and predicted that blinded viewers would be able to perceive changes in theoretically derived emotional profiles expressed in art made by military personnel with PTSS from the onset to the end of therapy. Five service members and veterans exhibiting PTSS were enrolled in an 8-session art therapy protocol, during which they artistically transformed papier-mâché masks at the beginning and end of the protocol. We found that blinded viewers without knowledge of the masks' creation stage (onset or end of therapy) read initial masks as conveying more negative emotions (e.g., angry, upset, and challenged) and later masks as conveying more positive emotions (calm and pleasure). Based on the assessments from the blinded evaluators, we infer the emotional transition experienced by the participants was expressed in the masks. In an exploratory arm of the study, we also found that viewers were better able to empathize with the negative emotions experienced by participants with PTSS when asked to explicitly take their perspective.
    Mesh-Begriff(e) Humans ; Military Personnel ; Art Therapy ; Stress Disorders, Post-Traumatic/psychology ; Veterans ; Irritable Mood
    Sprache Englisch
    Erscheinungsdatum 2024-03-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57128-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Improving patient experience for people prescribed medicines with a risk of dependence or withdrawal: co-designed solutions using experience based co-design.

    Seddon, Jennifer / Friedrich, Claire / Wadd, Sarah / Dicks, David / Scott, Sion / Robinson, Anthea / Walker, Charlotte

    BMC primary care

    2024  Band 25, Heft 1, Seite(n) 17

    Abstract: Background: Significant concerns have been raised regarding how medications with a risk of dependence or withdrawal are managed and how care is experienced by patients. This study sought to co-design solutions to improve the experience of care for ... ...

    Abstract Background: Significant concerns have been raised regarding how medications with a risk of dependence or withdrawal are managed and how care is experienced by patients. This study sought to co-design solutions to improve the experience of care for patients prescribed benzodiazepines, z-drugs, opioids for chronic non-cancer pain, gabapentinoids and antidepressants.
    Method: Twenty patients and fifteen healthcare professionals from five different GP practices were recruited to take part. The study used Experience Based Co-Design. Patients and healthcare professionals completed semi-structured interviews and took part in feedback groups and co-design workshops to collaboratively identify priorities for improvement and to co-design solutions to improve the experience of care.
    Results: Poor patient experience was common among people prescribed medications with a risk of dependence or withdrawal. Patients and healthcare professionals identified three main priority areas to improve the experience of care: (i) ensuring patients are provided with detailed information in relation to their medication, (ii) ensuring continuity of care for patients, and (iii) providing alternative treatment options to medication. Solutions to improve care were co-designed by patients and healthcare staff and implemented within participating GP practices to improve the experience of care.
    Conclusion: Good patient experience is a key element of quality care. This study highlights that the provision of in-depth medication related information, continuity of care and alternative treatment to medication are important to patients prescribed medicines with a risk of dependence or withdrawal. Improving these aspects of care should be a priority for future improvement and delivery plans.
    Mesh-Begriff(e) Humans ; Analgesics, Opioid/adverse effects ; Chronic Pain/drug therapy ; Benzodiazepines/adverse effects ; Antisocial Personality Disorder ; Patient Outcome Assessment
    Chemische Substanzen Analgesics, Opioid ; Benzodiazepines (12794-10-4)
    Sprache Englisch
    Erscheinungsdatum 2024-01-06
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2731-4553
    ISSN (online) 2731-4553
    DOI 10.1186/s12875-023-02253-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Yellow Fever Emergence: Role of Heterologous Flavivirus Immunity in Preventing Urban Transmission.

    Shinde, Divya P / Plante, Jessica A / Scharton, Dionna / Mitchell, Brooke / Walker, Jordyn / Azar, Sasha R / Campos, Rafael K / Sacchetto, Lívia / Drumond, Betânia P / Vasilakis, Nikos / Plante, Kenneth S / Weaver, Scott C

    bioRxiv : the preprint server for biology

    2024  

    Abstract: During major, recent yellow fever (YF) epidemics in Brazil, human cases were attributed only to spillover infections from sylvatic transmission with no evidence of human amplification. Furthermore, the historic absence of YF in Asia, despite abundant ... ...

    Abstract During major, recent yellow fever (YF) epidemics in Brazil, human cases were attributed only to spillover infections from sylvatic transmission with no evidence of human amplification. Furthermore, the historic absence of YF in Asia, despite abundant peridomestic
    One-sentence summary: Immunity from dengue and Zika viruses suppresses yellow fever viremia, preventing infection of mosquitoes and reducing the risk of epidemics.
    Sprache Englisch
    Erscheinungsdatum 2024-03-03
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2024.03.03.583168
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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