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  1. Article ; Online: Bloqueo anestésico del nervio occipital mayor en el tratamiento de las cefaleas. Revisión de la evidencia.

    Castillo-Álvarez, Federico / Hernando de la Bárcena, Ignacio / Marzo-Sola, María Eugenia

    Medicina clinica

    2023  Volume 161, Issue 3, Page(s) 113–118

    Abstract: Introduction: Peripheral nerve blocks have been a common treatment for multiple headaches. By far, the greater occipital nerve block is the most used and with the stronger body of evidence in routine clinical practice.: Methods: We searched Pubmed ... ...

    Title translation Greater occipital nerve block in the treatment of headaches. Review of evidence.
    Abstract Introduction: Peripheral nerve blocks have been a common treatment for multiple headaches. By far, the greater occipital nerve block is the most used and with the stronger body of evidence in routine clinical practice.
    Methods: We searched Pubmed Meta-Analysis/Systematic Review, in the last 10 years. Of these results, meta-analyses, and in the absence of these systematic reviews, assessing Greater Occipital Nerve Block in headache has been selected for review.
    Results: We identified 95 studies in Pubmed, 13 that met the inclusion criteria.
    Conclusion: Greater occipital block is an effective and safe technique, easy to perform and which has shown its usefulness in migraine, cluster headache, cervicogenic headache and Post-dural puncture headache. However, more studies are needed to clarify its long-term efficacy, its place in clinical treatment, the possible difference between different anaesthetics, the most convenient dosage and the role of concomitant use of corticosteroids.
    MeSH term(s) Humans ; Cluster Headache ; Headache/therapy ; Migraine Disorders/therapy ; Nerve Block/methods ; Peripheral Nerves ; Meta-Analysis as Topic ; Systematic Reviews as Topic
    Language Spanish
    Publishing date 2023-04-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2023.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Risk of SARS-CoV-2 infection and clinical outcomes in multiple sclerosis patients in La Rioja (Spain): Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con esclerosis múltiple en la Rioja (España).

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia

    Medicina clinica (English ed.)

    2020  Volume 155, Issue 8, Page(s) 362–363

    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country Spain
    Document type Case Reports
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con esclerosis múltiple en la Rioja (España).

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia

    Medicina clinica

    2020  Volume 155, Issue 8, Page(s) 362–363

    Title translation Risk of SARS-CoV-2 infection and clinical outcomes in multiple sclerosis patients in La Rioja (Spain).
    MeSH term(s) Adult ; Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/etiology ; Coronavirus Infections/therapy ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Multiple Sclerosis/complications ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/etiology ; Pneumonia, Viral/therapy ; Prognosis ; Risk Factors ; SARS-CoV-2 ; Severity of Illness Index ; Spain
    Keywords covid19
    Language Spanish
    Publishing date 2020-07-09
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.06.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Disease of the holobiont, the example of multiple sclerosis.

    Castillo-Álvarez, Federico / Marzo-Sola, María Eugenia

    Medicina clinica

    2018  Volume 152, Issue 4, Page(s) 147–153

    Abstract: In recent years there has been a revolution regarding the role of the microbiota in different diseases, most of them within the spectrum of inflammatory and autoimmune diseases, associated with the development of metagenomics and the concept of holobiont, ...

    Title translation El holobionte enfermo, el ejemplo de la esclerosis múltiple.
    Abstract In recent years there has been a revolution regarding the role of the microbiota in different diseases, most of them within the spectrum of inflammatory and autoimmune diseases, associated with the development of metagenomics and the concept of holobiont, a large organism together with its microbiota. Specifically, in Multiple Sclerosis, multiple evidence points to the role of the microbiota in experimental autoimmune encephalomyelitis, animal model of the disease, and several articles have been published in recent years about differences in intestinal microbiota among patients with multiple sclerosis and control subjects. We review in this article the concept of holobiont and the gut microbiota functions, as well as the evidence accumulated about the role of the microbiota in experimental autoimmune encephalomyelitis and multiple sclerosis. Nowadays, there is a lot of evidence showing the role of the microbiota in the genesis, prevention and treatment of experimental autoimmune encephalomyelitis based mainly on three immunological pillars, the Th1-Th17 / Th2 balance, the Treg cells and the humoral immunity. It is also well documented that there are differences in the microbiota of patients with MS that are associated with a different expression of genes related to inflammation.
    MeSH term(s) Animals ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Encephalomyelitis, Autoimmune, Experimental/microbiology ; Encephalomyelitis, Autoimmune, Experimental/prevention & control ; Female ; Gastrointestinal Microbiome/genetics ; Gastrointestinal Microbiome/physiology ; Humans ; Immunity, Cellular ; Male ; Multiple Sclerosis/microbiology ; Sex Factors ; Symbiosis
    Language Spanish
    Publishing date 2018-11-10
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2018.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk of SARS-CoV-2 infection and clinical outcomes in multiple sclerosis patients in La Rioja (Spain)

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia

    Medicina Clínica (English Edition)

    2020  Volume 155, Issue 8, Page(s) 362–363

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2387-0206
    DOI 10.1016/j.medcle.2020.06.017
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con esclerosis múltiple en la Rioja (España)

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia

    Medicina Clínica

    2020  Volume 155, Issue 8, Page(s) 362–363

    Keywords General Medicine ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.06.021
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article: Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con esclerosis múltiple en la Rioja (España)./ Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con esclerosis múltiple en la Rioja (España)./ [Risk of SARS-CoV-2 infection and clinical outcomes in multiple sclerosis patients in La Rioja (Spain)]

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia

    Med Clin (Barc)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #643981
    Database COVID19

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  8. Article: Risk of SARS-CoV-2 infection and clinical outcomes in multiple sclerosis patients in La Rioja (Spain): [[es]]Riesgo de infección por SARS-CoV-2 y resultados clínicos en pacientes con Esclerosis Múltiple en la Rioja (España)

    Castillo Álvarez, Federico / López Pérez, Mª Ángeles / Marzo Sola, María Eugenia
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #808934
    Database COVID19

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  9. Article ; Online: Decalogue to promote the implementation and improvement of recommendations for the early diagnosis of HIV in Emergency Departments.

    González Del Castillo, Juan / Perez Elias, Maria Jesus / Miguens, Iría / Espinosa, Begoña / Juárez, Ricardo / Piedrafita Lozoya, Lourdes / Trenc, Patricia / Alvarez Manzanares, Jesús / Marchena, María José / Rodríguez, Raquel / Cabrera, Nayra / Grajal, Pilar / Navarro, Carmen / Piñera, Pascual / García, Federico / Moreno, Santiago / Miro, Oscar

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2023  

    Abstract: Early diagnosis of HIV is still a challenge. Emergency Departments (EDs) suppose ideal settings for the early detection of HIV, since patients with high prevalence of hidden HIV infection are frequently attending those services. In 2020, the Spanish ... ...

    Abstract Early diagnosis of HIV is still a challenge. Emergency Departments (EDs) suppose ideal settings for the early detection of HIV, since patients with high prevalence of hidden HIV infection are frequently attending those services. In 2020, the Spanish Society of Emergency and Emergency Medicine (SEMES) published a series of recommendations for the early diagnosis of patients with suspected HIV infection and their referral and follow-up in the EDs as part of its "Deja tu huella" program. However, the application of these recommendations has been very heterogeneous in our country. Considering this, the working group of the HIV hospital network led by the SEMES has motivated the drafting of a decalogue, with the aim of promoting the implementation and improvement of protocols for the early diagnosis of HIV in Spanish EDs.
    Language English
    Publishing date 2023-06-14
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2023.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Botulinum toxin in trigeminal neuralgia.

    Castillo-Álvarez, Federico / Hernando de la Bárcena, Ignacio / Marzo-Sola, María Eugenia

    Medicina clinica

    2017  Volume 148, Issue 1, Page(s) 28–32

    Abstract: Introduction: Trigeminal neuralgia is one of the most disabling facial pain syndromes, with a significant impact on patients' quality of life. Pharmacotherapy is the first choice for treatment but cases of drug resistance often require new strategies, ... ...

    Title translation Toxina botulínica en la neuralgia del trigémino.
    Abstract Introduction: Trigeminal neuralgia is one of the most disabling facial pain syndromes, with a significant impact on patients' quality of life. Pharmacotherapy is the first choice for treatment but cases of drug resistance often require new strategies, among which various interventional treatments have been used. In recent years a new therapeutic strategy consisting of botulinum toxin has emerged, with promising results.
    Development: We reviewed clinical cases and case series, open-label studies and randomized clinical trials examining the use of botulinum toxin for drug-refractory trigeminal neuralgia published in the literature.
    Conclusions: The administration of botulinum toxin has proven to be a safe and effective therapeutic strategy in patients with drug-refractory idiopathic trigeminal neuralgia, but many questions remain unanswered as to the precise role of botulinum toxin in the treatment of this disease.
    Language Spanish
    Publishing date 2017-01-06
    Publishing country Spain
    Document type Review ; Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2016.07.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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