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  1. Article: A nomogram predicting the severity of COVID-19 based on initial clinical and radiologic characteristics.

    Zhang, Hanfei / Zhong, Feiyang / Wang, Binchen / Liao, Meiyan

    Future virology

    2022  

    Abstract: Aim: ...

    Abstract Aim:
    Language English
    Publishing date 2022-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254606-6
    ISSN 1746-0808 ; 1746-0794
    ISSN (online) 1746-0808
    ISSN 1746-0794
    DOI 10.2217/fvl-2020-0193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: FinKENet: A Novel Financial Knowledge Enhanced Network for Financial Question Matching.

    Guo, Yu / Liang, Ting / Chen, Zhongpu / Yang, Binchen / Wang, Jun / Zhao, Yu

    Entropy (Basel, Switzerland)

    2023  Volume 26, Issue 1

    Abstract: Question matching is the fundamental task in retrieval-based dialogue systems which assesses the similarity between Query and Question. Unfortunately, existing methods focus on improving the accuracy of text similarity in the general domain, without ... ...

    Abstract Question matching is the fundamental task in retrieval-based dialogue systems which assesses the similarity between Query and Question. Unfortunately, existing methods focus on improving the accuracy of text similarity in the general domain, without adaptation to the financial domain. Financial question matching has two critical issues: (1) How to accurately model the contextual representation of a financial sentence? (2) How to accurately represent financial key phrases in an utterance? To address these issues, this paper proposes a novel
    Language English
    Publishing date 2023-12-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e26010026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mechanism of thermal oxidation into volatile compounds from (E)-4-decenal: A density functional theory study.

    Wang, Binchen / Dou, Shaohua / Wang, Shang / Wang, Yi / Zhang, Sufang / Lin, Xinping / Chen, Yingxi / Ji, Chaofan / Dai, Yiwei / Dong, Liang

    Food chemistry: X

    2024  Volume 21, Page(s) 101174

    Abstract: Unsaturated aliphatic aldehyde oxidation plays a significant role in the deep oxidation of fatty acids to produce volatile chemicals. Exposing the oxidation process of unsaturated aliphatic aldehydes is crucial to completely comprehend how food flavor ... ...

    Abstract Unsaturated aliphatic aldehyde oxidation plays a significant role in the deep oxidation of fatty acids to produce volatile chemicals. Exposing the oxidation process of unsaturated aliphatic aldehydes is crucial to completely comprehend how food flavor forms. In this study, thermal desorption cryo-trapping in conjunction with gas chromatography-mass spectrometry was used to examine the volatile profile of (E)-4-decenal during heating, and 32 volatile compounds in all were detected and identified. Meanwhile, density functional theory (DFT) calculations were used, and 43 reactions were obtained in the 24 pathways, which were summarized into the peroxide reaction mechanism (ROOH), the peroxyl radical reaction mechanism (ROO·) and the alkoxy radical reaction mechanism (RO·). Moreover, the priority of these three oxidative mechanisms was the RO· mechanism > ROOH mechanism > ROO· mechanism. Furthermore, the DFT results and experimental results agreed well, and the oxidative mechanism of (E)-4-decenal was finally illuminated.
    Language English
    Publishing date 2024-02-06
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2024.101174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The diagnostic value of CT-guided percutaneous puncture biopsy of pulmonary ground-glass nodules: a meta-analysis.

    Wang, Binchen / Zhong, Feiyang / An, Wenting / Liao, Meiyan

    Acta radiologica (Stockholm, Sweden : 1987)

    2022  Volume 64, Issue 4, Page(s) 1431–1438

    Abstract: Background: More and more pulmonary ground-glass nodules (GGNs) are screened with the extensive usage of low-dose computed tomography (CT). The need of CT-guided percutaneous puncture biopsy of GGN remains controversial.: Purpose: To explore the ... ...

    Abstract Background: More and more pulmonary ground-glass nodules (GGNs) are screened with the extensive usage of low-dose computed tomography (CT). The need of CT-guided percutaneous puncture biopsy of GGN remains controversial.
    Purpose: To explore the diagnostic accuracy of CT-guided percutaneous puncture biopsy of GGNs.
    Material and methods: We searched PubMed, EMBASE, the Cochrane Library, and CNKI. Included studies reported the puncture biopsy results of pulmonary GGNs, including the number of true positive (TP), false positive (FP), true negative (TN), and false negative (FN) cases. After evaluating the studies, statistical analysis, and quality assessment, the pooled diagnostic sensitivity (SEN), specificity (SPE), and diagnostic odds ratio (DOR) were calculated. The summary receiver operating characteristic (SROC) curve was constructed and the area under the curve (AUC) was calculated. Subgroup analysis was performed according to whether spiral CT or fluoroscopy-guided CT was used in the study.
    Results: This meta-analysis included 14 studies with a total of 759 patients (702 samples). The pooled SEN, SPE, and DOR of CT-guided puncture biopsy of pulmonary GGNs were 0.91 (95% confidence interval [CI] = 0.89-0.94), 0.99 (95% CI = 0.95-1.00), and 138.72 (95% CI = 57.98-331.89), respectively. The AUC was 0.97.
    Conclusion: Our results indicated that CT-guided puncture biopsy of GGNs has high SEN, SPE, and DOR, which proved that CT-guided puncture biopsy was a good way to determine the pathological nature of GGN.
    MeSH term(s) Humans ; Tomography, X-Ray Computed/methods ; Multiple Pulmonary Nodules/diagnostic imaging ; Tomography, Spiral Computed ; Sensitivity and Specificity ; Biopsy, Needle
    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 105-3
    ISSN 1600-0455 ; 0284-1851 ; 0349-652X
    ISSN (online) 1600-0455
    ISSN 0284-1851 ; 0349-652X
    DOI 10.1177/02841851221137693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comparison of CT-Guided Core Needle Biopsy in Pulmonary Ground-Glass and Solid Nodules Based on Propensity Score Matching Analysis.

    An, Wenting / Zhang, Hanfei / Wang, Binchen / Zhong, Feiyang / Wang, Shan / Liao, Meiyan

    Technology in cancer research & treatment

    2022  Volume 21, Page(s) 15330338221085357

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Biopsy, Large-Core Needle/methods ; Hemorrhage/etiology ; Humans ; Image-Guided Biopsy/adverse effects ; Lung Neoplasms/diagnosis ; Multiple Pulmonary Nodules/diagnostic imaging ; Pneumothorax ; Propensity Score ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2146365-7
    ISSN 1533-0338 ; 1533-0346
    ISSN (online) 1533-0338
    ISSN 1533-0346
    DOI 10.1177/15330338221085357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Density functional theory studies on the oleic acid thermal oxidation into volatile compounds.

    Xiao, Lin / Wang, Shang / Wang, Yi / Wang, Binchen / Ji, Chaofan / Lin, Xinping / Liang, Huipeng / Zhang, Sufang / Xu, Xianbing / Dong, Liang

    Food chemistry: X

    2023  Volume 19, Page(s) 100737

    Abstract: Oleic acid oxidation is one of the main sources of food flavor compounds. Volatile profiling was investigated using thermal desorption cryo-trapping combined with gas chromatography-mass spectrometry to analyze the volatile composition of oleic acid ... ...

    Abstract Oleic acid oxidation is one of the main sources of food flavor compounds. Volatile profiling was investigated using thermal desorption cryo-trapping combined with gas chromatography-mass spectrometry to analyze the volatile composition of oleic acid oxidation. A total of 43 volatile compounds, including aldehydes (11), ketones (2), alcohols (5), furans (2), acids (8), ester (12) and alkane (3) were identified from oleic acid during heating. Then, density functional theory (DFT) was applied to analyze the oxidative mechanism of oleic acid during heating. A total of 30 reactions were obtained and grouped into the peroxide (ROOH), alkoxy radical (RO•), and peroxide radical (ROO•) pathways. The structures of intermediates, transition states (TS), and products in each reaction were also determined. Results show that the branch chemical reactions were the key reactions in different reaction pathway. Moreover, the reaction priority of the thermal oxidation reaction of oleic acid was the peroxide radical mechanism > the peroxide mechanism > the alkoxy radical mechanism.
    Language English
    Publishing date 2023-06-07
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2023.100737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Density functional theory studies on the oleic acid thermal oxidation into volatile compounds

    Lin Xiao / Shang Wang / Yi Wang / Binchen Wang / Chaofan Ji / Xinping Lin / Huipeng Liang / Sufang Zhang / Xianbing Xu / Liang Dong

    Food Chemistry: X, Vol 19, Iss , Pp 100737- (2023)

    2023  

    Abstract: Oleic acid oxidation is one of the main sources of food flavor compounds. Volatile profiling was investigated using thermal desorption cryo-trapping combined with gas chromatography–mass spectrometry to analyze the volatile composition of oleic acid ... ...

    Abstract Oleic acid oxidation is one of the main sources of food flavor compounds. Volatile profiling was investigated using thermal desorption cryo-trapping combined with gas chromatography–mass spectrometry to analyze the volatile composition of oleic acid oxidation. A total of 43 volatile compounds, including aldehydes (11), ketones (2), alcohols (5), furans (2), acids (8), ester (12) and alkane (3) were identified from oleic acid during heating. Then, density functional theory (DFT) was applied to analyze the oxidative mechanism of oleic acid during heating. A total of 30 reactions were obtained and grouped into the peroxide (ROOH), alkoxy radical (RO•), and peroxide radical (ROO•) pathways. The structures of intermediates, transition states (TS), and products in each reaction were also determined. Results show that the branch chemical reactions were the key reactions in different reaction pathway. Moreover, the reaction priority of the thermal oxidation reaction of oleic acid was the peroxide radical mechanism > the peroxide mechanism > the alkoxy radical mechanism.
    Keywords Oleic acid oxidation ; Flavor ; Density functional theory ; GC–MS ; Quantum chemistry ; Nutrition. Foods and food supply ; TX341-641 ; Food processing and manufacture ; TP368-456
    Subject code 540 ; 660
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Deep exploration of lipid oxidation into flavor compounds: A density functional theory study on (E)-2-decenal thermal oxidative reaction.

    Wang, Binchen / Wang, Shang / Wang, Yi / Zhang, Sufang / Lin, Xinping / Xu, Xianbing / Ji, Chaofan / Liang, Huipeng / Dong, Liang

    Food chemistry

    2023  Volume 428, Page(s) 136725

    Abstract: Unsaturated fatty aldehydes are the main products of fatty acid oxidation, and could be further oxidized to form volatile compounds with shorter carbon chains. Therefore, studying the oxidation of unsaturated fatty aldehydes is an important way to reveal ...

    Abstract Unsaturated fatty aldehydes are the main products of fatty acid oxidation, and could be further oxidized to form volatile compounds with shorter carbon chains. Therefore, studying the oxidation of unsaturated fatty aldehydes is an important way to reveal the mechanism of food flavor formation during heating. In this study, volatile profiling of (E)-2-decenal during heating was firstly investigated by using thermal-desorption cryo-trapping combined with gas chromatography-mass spectrometry (GC-MS). A total of 38 volatile compounds were detected. Then, twenty-one reactions in the heating process of (E)-2-decenal were obtained by using density functional theory (DFT) calculations, and grouped into three oxidation pathways, namely, peroxide pathway, peroxyl radical pathway and alkoxy radical pathway. Meanwhile, the priority of these three pathways was the alkoxy radical reaction pathway > peroxide pathway > peroxyl radical reaction pathway. Moreover, the calculated results agreed well with the experimental results.
    MeSH term(s) Density Functional Theory ; Fatty Acids/analysis ; Peroxides ; Aldehydes/analysis ; Oxidative Stress ; Volatile Organic Compounds/analysis
    Chemical Substances perhydroxyl radical (3170-83-0) ; (2E)-decenal ; alkoxyl radical ; fatty aldehyde ; Fatty Acids ; Peroxides ; Aldehydes ; Volatile Organic Compounds
    Language English
    Publishing date 2023-06-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.136725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Development and Validation of a CT-Based Radiomics Nomogram in Patients With Anterior Mediastinal Mass: Individualized Options for Preoperative Patients.

    Zhou, Zhou / Qu, Yanjuan / Zhou, Yurong / Wang, Binchen / Hu, Weidong / Cao, Yiyuan

    Frontiers in oncology

    2022  Volume 12, Page(s) 869253

    Abstract: Background: To improve the preoperative diagnostic accuracy and reduce the non-therapeutic thymectomy rate, we established a comprehensive predictive nomogram based on radiomics data and computed tomography (CT) features and further explored its ... ...

    Abstract Background: To improve the preoperative diagnostic accuracy and reduce the non-therapeutic thymectomy rate, we established a comprehensive predictive nomogram based on radiomics data and computed tomography (CT) features and further explored its potential use in clinical decision-making for anterior mediastinal masses (AMMs).
    Methods: A total of 280 patients, including 280 with unenhanced CT (UECT) and 241 with contrast-enhanced CT (CECT) scans, all of whom had undergone thymectomy for AMM with confirmed histopathology, were enrolled in this study. A total of 1,288 radiomics features were extracted from each labeled mass. The least absolute shrinkage and selection operator model was used to select the optimal radiomics features in the training set to construct the radscore. Multivariate logistic regression analysis was conducted to establish a combined clinical radiographic radscore model, and an individualized prediction nomogram was developed.
    Results: In the UECT dataset, radscore and the UECT ratio were selected for the nomogram. The combined model achieved higher accuracy (AUC: 0.870) than the clinical model (AUC: 0.752) for the prediction of therapeutic thymectomy probability. In the CECT dataset, the clinical and combined models achieved higher accuracy (AUC: 0.851 and 0.836, respectively) than the radscore model (AUC: 0.618) for the prediction of therapeutic thymectomy probability.
    Conclusions: In patients who underwent UECT only, a nomogram integrating the radscore and the UECT ratio achieved good accuracy in predicting therapeutic thymectomy in AMMs. However, the use of radiomics in patients with CECT scans did not improve prediction performance; therefore, a clinical model is recommended.
    Language English
    Publishing date 2022-07-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.869253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Radiomics Study for Discriminating Second Primary Lung Cancers From Pulmonary Metastases in Pulmonary Solid Lesions.

    Zhong, Feiyang / Liu, Zhenxing / An, Wenting / Wang, Binchen / Zhang, Hanfei / Liu, Yumin / Liao, Meiyan

    Frontiers in oncology

    2022  Volume 11, Page(s) 801213

    Abstract: Background: The objective of this study was to assess the value of quantitative radiomics features in discriminating second primary lung cancers (SPLCs) from pulmonary metastases (PMs).: Methods: This retrospective study enrolled 252 malignant ... ...

    Abstract Background: The objective of this study was to assess the value of quantitative radiomics features in discriminating second primary lung cancers (SPLCs) from pulmonary metastases (PMs).
    Methods: This retrospective study enrolled 252 malignant pulmonary nodules with histopathologically confirmed SPLCs or PMs and randomly assigned them to a training or validation cohort. Clinical data were collected from the electronic medical records system. The imaging and radiomics features of each nodule were extracted from CT images.
    Results: A rad-score was generated from the training cohort using the least absolute shrinkage and selection operator regression. A clinical and radiographic model was constructed using the clinical and imaging features selected by univariate and multivariate regression. A nomogram composed of clinical-radiographic factors and a rad-score were developed to validate the discriminative ability. The rad-scores differed significantly between the SPLC and PM groups. Sixteen radiomics features and four clinical-radiographic features were selected to build the final model to differentiate between SPLCs and PMs. The comprehensive clinical radiographic-radiomics model demonstrated good discriminative capacity with an area under the curve of the receiver operating characteristic curve of 0.9421 and 0.9041 in the respective training and validation cohorts. The decision curve analysis demonstrated that the comprehensive model showed a higher clinical value than the model without the rad-score.
    Conclusion: The proposed model based on clinical data, imaging features, and radiomics features could accurately discriminate SPLCs from PMs. The model thus has the potential to support clinicians in improving decision-making in a noninvasive manner.
    Language English
    Publishing date 2022-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.801213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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