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  1. Article ; Online: Prone positioning.

    Guérin, Claude / Li, Jie / Grasselli, Giacomo

    Intensive care medicine

    2024  

    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07413-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hemoglobin Concentration and Viscoelastic Tests: Remember to Consider Fibrinogen and Platelets.

    Meli, Andrea / Grasselli, Giacomo / Panigada, Mauro

    Critical care medicine

    2023  Volume 51, Issue 5, Page(s) e122–e123

    MeSH term(s) Blood Platelets ; Fibrinogen ; Hemostatics ; Blood Coagulation ; Hemoglobins ; Adenosine Diphosphate/pharmacology
    Chemical Substances Fibrinogen (9001-32-5) ; Hemostatics ; Hemoglobins ; Adenosine Diphosphate (61D2G4IYVH)
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Research Support, Non-U.S. Gov't ; Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005799
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: "Reply on: statistics on steroids-how recognizing competing risks gets us closer to the truth about COVID-19-associated VAP".

    Madotto, Fabiana / Guzzardella, Amedeo / Scaravilli, Vittorio / Grasselli, Giacomo

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 100

    MeSH term(s) Humans ; Pneumonia, Ventilator-Associated/epidemiology ; Cohort Studies ; Respiration, Artificial/adverse effects ; Incidence ; COVID-19/complications ; COVID-19 Drug Treatment ; Intensive Care Units/statistics & numerical data ; Steroids ; Dexamethasone
    Chemical Substances Steroids ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04351-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Redefining ARDS: a paradigm shift.

    Villar, Jesús / Szakmany, Tamas / Grasselli, Giacomo / Camporota, Luigi

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 416

    Abstract: Although the defining elements of "acute respiratory distress syndrome" (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate ...

    Abstract Although the defining elements of "acute respiratory distress syndrome" (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate whether ARDS is a discrete nosological entity. After almost 60 years, it is appropriate to examine how critical care has modeled this fascinating syndrome and affected patient's outcome. Given that the diagnostic criteria of ARDS (e.g., increased pulmonary vascular permeability and diffuse alveolar damage) are difficult to ascertain in clinical practice, we believe that a step forward would be to standardize the assessment of pulmonary and extrapulmonary involvement in ARDS to ensure that each patient can receive the most appropriate and effective treatment. The selection of treatments based on arbitrary ranges of PaO
    MeSH term(s) Humans ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/drug therapy ; Lung ; Treatment Outcome ; Critical Care
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04699-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply: Can We Reliably Predict the Failure of Noninvasive Ventilation in COVID-19-associated Acute Hypoxemic Respiratory Failure?

    Bellani, Giacomo / Cecconi, Maurizio / Grasselli, Giacomo

    Annals of the American Thoracic Society

    2021  Volume 18, Issue 9, Page(s) 1595–1596

    MeSH term(s) COVID-19 ; Humans ; Hypoxia/etiology ; Hypoxia/therapy ; Noninvasive Ventilation ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy ; SARS-CoV-2
    Language English
    Publishing date 2021-05-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202103-398LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exploring Associations Between Respiratory Mechanics and Survival in Immunocompromised Patients With ARDS.

    Cortegiani, Andrea / Grasselli, Giacomo

    Chest

    2020  Volume 158, Issue 5, Page(s) 1812–1813

    MeSH term(s) Humans ; Immunocompromised Host ; Positive-Pressure Respiration ; Respiratory Distress Syndrome ; Respiratory Mechanics
    Language English
    Publishing date 2020-10-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.06.060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Agreement between the thromboelastography reaction time parameter using fresh and citrated whole blood during extracorporeal membrane oxygenation with Teg®5000 and Teg®6s.

    De Falco, Stefano / Meli, Andrea / Caccioppola, Alessio / Grasselli, Giacomo / Panigada, Mauro

    Perfusion

    2024  Volume 39, Issue 1_suppl, Page(s) 77S–80S

    Abstract: Purpose: We aimed at assessing the correlation between TEG reaction time (TEG-R) in citrated and fresh blood samples with TEG5000 and TEG 6S during heparin administration in patients with and without ECMO support.: Materials and methods: Paired ... ...

    Abstract Purpose: We aimed at assessing the correlation between TEG reaction time (TEG-R) in citrated and fresh blood samples with TEG5000 and TEG 6S during heparin administration in patients with and without ECMO support.
    Materials and methods: Paired TEG5000 (fresh and citrated whole blood, kaolin and kaolin-heparinase) and TEG6S (citrated whole blood) samples were obtained, together with standard coagulation laboratory tests. Bland-Altman analysis and Lin's concordance correlation coefficient were used to assess agreement.
    Results: Thirteen consecutive ECMO patients and eight consecutive non-ECMO patients were enrolled and TEG was performed for a total of 84 paired samples. ECMO patients received 19.2 (12.6-25.8) U/kg/h of heparin. Five of the non-ECMO patients did not receive heparin, two of them received a very low prophylactic dose (1.6 and 2.9 IU/kg/h, respectively), and one of them 13.1 U/kg/h of heparin. Using TEG®5000, TEG-R was 21.0 (-23.4; 65.5) min longer on fresh compared to citrated blood in patients receiving heparin while only 1.58 (-5.5; 8.7) min longer in patients not-receiving heparin. These differences were reverted by heparinase.
    Conclusions: Using citrated-recalcified blood to perform TEG might lead to underestimation of the effect of heparin.
    MeSH term(s) Humans ; Thrombelastography/methods ; Extracorporeal Membrane Oxygenation/methods ; Male ; Female ; Middle Aged ; Heparin/administration & dosage ; Heparin/pharmacology ; Adult ; Aged
    Chemical Substances Heparin (9005-49-6)
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/02676591231223085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Weaning from Mechanical Ventilation: Have We, so Far, Missed a Crucial Point?

    Grasselli, Giacomo / Bellani, Giacomo

    Anesthesiology

    2018  Volume 129, Issue 3, Page(s) 394–395

    MeSH term(s) Exhalation ; Humans ; Respiration, Artificial ; Respiratory Insufficiency ; Respiratory Muscles ; Ventilator Weaning
    Language English
    Publishing date 2018-07-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000002337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Critically ill patients with COVID-19 in New York City.

    Grasselli, Giacomo / Zanella, Alberto

    Lancet (London, England)

    2020  Volume 395, Issue 10239, Page(s) 1740–1741

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Critical Illness ; Humans ; New York City ; Pandemics ; Pneumonia, Viral ; Prospective Studies ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)31190-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to: Candidacy for Extracorporeal Membrane Oxygenation Should Start with Ventilatory Support Optimization.

    Rudym, Darya / Pham, Tài / Rackley, Craig R / Grasselli, Giacomo / Schmidt, Matthieu / Brodie, Daniel

    American journal of respiratory and critical care medicine

    2023  Volume 209, Issue 2, Page(s) 229–230

    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation ; Retrospective Studies
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202310-1783LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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