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  1. Article ; Online: The effects of curcumin supplementation on body mass index, body weight, and waist circumference in patients with nonalcoholic fatty liver disease: A systematic review and dose-response meta-analysis of randomized controlled trials.

    Baziar, Nima / Parohan, Mohammad

    Phytotherapy research : PTR

    2019  Volume 34, Issue 3, Page(s) 464–474

    Abstract: Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity; its prevalence is elevating due to the rising epidemic of obesity. Several clinical trials have examined the effects of curcumin supplementation on anthropometric ... ...

    Abstract Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity; its prevalence is elevating due to the rising epidemic of obesity. Several clinical trials have examined the effects of curcumin supplementation on anthropometric variables in NAFLD patients with inconclusive results. This dose-response meta-analysis aimed to evaluate the impact of curcumin supplementation on body mass index (BMI), body weight, and waist circumference (WC) in patients with NAFLD. A systematic review of the literature was conducted using PubMed/Medline, ISI Web of Science, Scopus, Cochrane Library, EMBASE, Google Scholar, Sid.ir, and Magiran.com to identify eligible studies up to March 2019. A meta-analysis of eligible studies was performed using the random-effects model to estimate the pooled effect size. Eight randomized controlled trials with 520 participants (curcumin group = 265 and placebo group = 255) were included. Supplementation dose and duration ranged from 70 to 3,000 mg/day and 8 to 12 weeks, respectively. Curcumin supplementation significantly reduced BMI (weighted mean difference [WMD] = -0.34 kg/m
    MeSH term(s) Adult ; Anthropometry ; Body Mass Index ; Body Weight/drug effects ; Curcumin/administration & dosage ; Dietary Supplements/analysis ; Female ; Humans ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/drug therapy ; Obesity/drug therapy ; Obesity/epidemiology ; Randomized Controlled Trials as Topic ; Waist Circumference/drug effects ; Weight Loss
    Chemical Substances Curcumin (IT942ZTH98)
    Language English
    Publishing date 2019-12-04
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.6542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cardiac injury is associated with severe outcome and death in patients with Coronavirus disease 2019 (COVID-19) infection: A systematic review and meta-analysis of observational studies.

    Parohan, Mohammad / Yaghoubi, Sajad / Seraji, Asal

    European heart journal. Acute cardiovascular care

    2020  Volume 9, Issue 6, Page(s) 665–677

    Abstract: Coronavirus disease 2019 (COVID-19) is a global pandemic impacting 213 countries/territories and more than 5,934,936 patients worldwide. Cardiac injury has been reported to occur in severe and death cases. This meta-analysis was done to summarize ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is a global pandemic impacting 213 countries/territories and more than 5,934,936 patients worldwide. Cardiac injury has been reported to occur in severe and death cases. This meta-analysis was done to summarize available findings on the association between cardiac injury and severity of COVID-19 infection. Online databases including Scopus, PubMed, Web of Science, Cochrane Library and Google Scholar were searched to detect relevant publications up to 20 May 2020, using relevant keywords. To pool data, a fixed- or random-effects model was used depending on the heterogeneity between studies. In total, 22 studies with 3684 COVID-19 infected patients (severe cases=1095 and death cases=365) were included in this study. Higher serum levels of lactate dehydrogenase (weighted mean difference (WMD) =108.86 U/L, 95% confidence interval (CI)=75.93-141.79,
    MeSH term(s) Betacoronavirus ; Biomarkers/blood ; COVID-19 ; Coronavirus Infections/epidemiology ; Creatine Kinase, MB Form/blood ; Heart Diseases/etiology ; Heart Diseases/metabolism ; Humans ; Myocardium/metabolism ; Observational Studies as Topic ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Troponin I/blood
    Chemical Substances Biomarkers ; Troponin I ; Creatine Kinase, MB Form (EC 2.7.3.2)
    Keywords covid19
    Language English
    Publishing date 2020-06-21
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1177/2048872620937165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Liver injury is associated with severe coronavirus disease 2019 (COVID-19) infection: A systematic review and meta-analysis of retrospective studies.

    Parohan, Mohammad / Yaghoubi, Sajad / Seraji, Asal

    Hepatology research : the official journal of the Japan Society of Hepatology

    2020  Volume 50, Issue 8, Page(s) 924–935

    Abstract: The coronavirus disease 2019 (COVID-19) outbreak is a major threat to human beings. Lung injury has been reported as the major outcome of COVID-19 infection. However, liver damage has also been considered to occur in severe cases. The current meta- ... ...

    Abstract The coronavirus disease 2019 (COVID-19) outbreak is a major threat to human beings. Lung injury has been reported as the major outcome of COVID-19 infection. However, liver damage has also been considered to occur in severe cases. The current meta-analysis of retrospective studies was carried out to summarize available findings on the association between liver injury and severity of COVID-19 infection. Online databases including PubMed, Scopus, Web of Science, and Cochrane Library were searched to detect relevant publications up to 1 April 2020, using relevant keywords. To pool data, a fixed- or random-effects model was used depending on the heterogeneity between studies. Furthermore, publication bias test and sensitivity analysis were also applied. In total, 20 retrospective studies with 3428 COVID-19 infected patients (severe cases, n = 1455; mild cases, n = 1973), were included in this meta-analysis. Higher serum levels of aspartate aminotransferase (weighted mean difference, 8.84 U/L; 95% confidence interval [CI] 5.97 to 11.71; P < 0.001), alanine aminotransferase (weighted mean difference, 7.35 U/L; 95% CI, 4.77 to 9.93; P < 0.001), total bilirubin (weighted mean difference, 2.30 mmol/L; 95% CI, 1.24 to 3.36; P < 0.001), and lower serum levels of albumin (weighted mean difference, -4.24 g/L; 95% CI, -6.20 to -2.28; P < 0.001) were associated with a significant increase in the severity of COVID-19 infection. The incidence of liver injury, as assessed by serum analysis (aspartate aminotransferase, alanine aminotransferase, total bilirubin, and albumin levels), seems to be higher in patients with severe COVID-19 infection.
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1387041-5
    ISSN 1386-6346 ; 0928-4346
    ISSN 1386-6346 ; 0928-4346
    DOI 10.1111/hepr.13510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Dietary and Biochemical Characteristics Associated with Normal-Weight Obesity.

    Amani, Reza / Parohan, Mohammad / Jomehzadeh, Nabi / Haghighizadeh, Mohammad Hossein

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2019  Volume 89, Issue 5-6, Page(s) 331–336

    MeSH term(s) Adipose Tissue ; Body Mass Index ; Case-Control Studies ; Diet ; Female ; Humans ; Male ; Obesity ; Overweight
    Language English
    Publishing date 2019-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Metformin Therapy Reduces Obesity Indices in Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

    Sadeghi, Alireza / Mousavi, Seyed Mohammad / Mokhtari, Tahereh / Parohan, Mohammad / Milajerdi, Alireza

    Childhood obesity (Print)

    2020  Volume 16, Issue 3, Page(s) 174–191

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2639910-6
    ISSN 2153-2176 ; 2153-2168
    ISSN (online) 2153-2176
    ISSN 2153-2168
    DOI 10.1089/chi.2019.0040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The effects of curcumin supplementation on body mass index, body weight, and waist circumference in patients with nonalcoholic fatty liver disease: A systematic review and dose–response meta‐analysis of randomized controlled trials

    Baziar, Nima / Parohan, Mohammad

    Phytotherapy research. 2020 Mar., v. 34, no. 3

    2020  

    Abstract: Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver‐related morbidity; its prevalence is elevating due to the rising epidemic of obesity. Several clinical trials have examined the effects of curcumin supplementation on anthropometric ... ...

    Abstract Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver‐related morbidity; its prevalence is elevating due to the rising epidemic of obesity. Several clinical trials have examined the effects of curcumin supplementation on anthropometric variables in NAFLD patients with inconclusive results. This dose–response meta‐analysis aimed to evaluate the impact of curcumin supplementation on body mass index (BMI), body weight, and waist circumference (WC) in patients with NAFLD. A systematic review of the literature was conducted using PubMed/Medline, ISI Web of Science, Scopus, Cochrane Library, EMBASE, Google Scholar, Sid.ir, and Magiran.com to identify eligible studies up to March 2019. A meta‐analysis of eligible studies was performed using the random‐effects model to estimate the pooled effect size. Eight randomized controlled trials with 520 participants (curcumin group = 265 and placebo group = 255) were included. Supplementation dose and duration ranged from 70 to 3,000 mg/day and 8 to 12 weeks, respectively. Curcumin supplementation significantly reduced BMI (weighted mean difference [WMD] = −0.34 kg/m2, 95% CI [−0.64, −0.04], p < .05) and WC (WMD = −2.12 cm, 95% CI [−3.26, −0.98], p < .001). However, no significant effects of curcumin supplementation on body weight were found. These results suggest that curcumin supplementation might have a positive effect on visceral fat and abdominal obesity that have been associated with NAFLD.
    Keywords body mass index ; curcumin ; dose response ; fatty liver ; meta-analysis ; morbidity ; obesity ; patients ; placebos ; randomized clinical trials ; statistical models ; systematic review ; visceral fat ; waist circumference
    Language English
    Dates of publication 2020-03
    Size p. 464-474.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note REVIEW
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.6542
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies.

    Parohan, Mohammad / Yaghoubi, Sajad / Seraji, Asal / Javanbakht, Mohammad Hassan / Sarraf, Payam / Djalali, Mahmoud

    The aging male : the official journal of the International Society for the Study of the Aging Male

    2020  Volume 23, Issue 5, Page(s) 1416–1424

    Abstract: Purpose: Coronavirus disease 2019 (COVID-19) is an emerging disease that was first reported in Wuhan city, the capital of Hubei province in China, and has subsequently spread worldwide. Risk factors for mortality have not been well summarized. Current ... ...

    Abstract Purpose: Coronavirus disease 2019 (COVID-19) is an emerging disease that was first reported in Wuhan city, the capital of Hubei province in China, and has subsequently spread worldwide. Risk factors for mortality have not been well summarized. Current meta-analysis of retrospective cohort studies was done to summarize available findings on the association between age, gender, comorbidities and risk of death from COVID-19 infection.
    Methods: Online databases including Web of Science, PubMed, Scopus, Cochrane Library and Google scholar were searched to detect relevant publications up to 1 May 2020, using relevant keywords. To pool data, random-effects model was used. Furthermore, sensitivity analysis and publication bias test were also done.
    Results: In total, 14 studies with 29,909 COVID-19 infected patients and 1445 cases of death were included in the current meta-analysis. Significant associations were found between older age (≥65 vs <65 years old) (pooled ORs = 4.59, 95%CIs = 2.61-8.04,
    Conclusions: Older age (≥65 years old), male gender, hypertension, CVDs, diabetes, COPD and malignancies were associated with greater risk of death from COVID-19 infection. These findings could help clinicians to identify patients with poor prognosis at an early stage.
    MeSH term(s) Age Factors ; COVID-19/diagnosis ; COVID-19/mortality ; Comorbidity ; Humans ; Mortality ; Observational Studies as Topic ; Prognosis ; Risk Assessment ; Risk Factors ; SARS-CoV-2/isolation & purification ; Sex Factors
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2108146-3
    ISSN 1473-0790 ; 1368-5538
    ISSN (online) 1473-0790
    ISSN 1368-5538
    DOI 10.1080/13685538.2020.1774748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Liver injury is associated with severe coronavirus disease 2019 (COVID‐19) infection

    Parohan, Mohammad / Yaghoubi, Sajad / Seraji, Asal

    Hepatology Research ; ISSN 1386-6346 1872-034X

    A systematic review and meta‐analysis of retrospective studies

    2020  

    Keywords Hepatology ; Infectious Diseases ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/hepr.13510
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Effects of Coffee, Black Tea and Green Tea Consumption on the Risk of Non-Hodgkin's Lymphoma: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies.

    Mirtavoos-Mahyari, Hanifeh / Salehipour, Pouya / Parohan, Mohammad / Sadeghi, Alireza

    Nutrition and cancer

    2019  Volume 71, Issue 6, Page(s) 887–897

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Coffee ; Dose-Response Relationship, Drug ; Humans ; Incidence ; Lymphoma, Non-Hodgkin/epidemiology ; Lymphoma, Non-Hodgkin/etiology ; Lymphoma, Non-Hodgkin/prevention & control ; Observational Studies as Topic ; Risk Factors ; Tea
    Chemical Substances Coffee ; Tea
    Language English
    Publishing date 2019-05-02
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 424433-3
    ISSN 1532-7914 ; 0163-5581
    ISSN (online) 1532-7914
    ISSN 0163-5581
    DOI 10.1080/01635581.2019.1595055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effect of coenzyme Q10 supplementation on clinical features of migraine: a systematic review and dose-response meta-analysis of randomized controlled trials.

    Parohan, Mohammad / Sarraf, Payam / Javanbakht, Mohammad Hassan / Ranji-Burachaloo, Sakineh / Djalali, Mahmoud

    Nutritional neuroscience

    2019  Volume 23, Issue 11, Page(s) 868–875

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Antioxidants/administration & dosage ; Dietary Supplements ; Humans ; Migraine Disorders/diet therapy ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Ubiquinone/administration & dosage ; Ubiquinone/analogs & derivatives
    Chemical Substances Antioxidants ; Ubiquinone (1339-63-5) ; coenzyme Q10 (EJ27X76M46)
    Language English
    Publishing date 2019-02-06
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1447449-9
    ISSN 1476-8305 ; 1028-415X
    ISSN (online) 1476-8305
    ISSN 1028-415X
    DOI 10.1080/1028415X.2019.1572940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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