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Article ; Online: Standing NiFe LDH nanosheets on stainless steel fibers felt

Yanqi Liu / Zhaohai Song / Zheng Li / Minmin Han / Yongliang Cheng / Zongmin Zheng

Catalysis Communications, Vol 164, Iss , Pp 106425- (2022)

A synergistic impact on the oxygen evolution reaction (OER) for the water splitting

2022

Abstract: Controllable preparation of NiFe layered double hydroxides (LDH) on suitable conductive substrate is always a key precondition for their wide applications. Standing NiFe LDH nanosheets were successfully grown on stainless steel fibers felt (SSFF) at room ...

Abstract	Controllable preparation of NiFe layered double hydroxides (LDH) on suitable conductive substrate is always a key precondition for their wide applications. Standing NiFe LDH nanosheets were successfully grown on stainless steel fibers felt (SSFF) at room temperature. The prepared SSFF@ NiFe LDH electrocatalyst displayed a high electrocatalytic performance for the oxygen evolution reaction (OER) in alkaline electrolyte as well as alkaline seawater. The effects of mass loading and molar ratio of Ni/Fe on the electrocatalytic activity were also evaluated. With the optimized electrode, the overpotential for the anodic OER process only needs 198 and 260 mV at a current density of 10 and 300 mA cm−2, respectively.
Keywords	Stainless steel ; NiFe LDH ; OER ; Water splitting ; Alkaline seawater ; Chemistry ; QD1-999
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Carbon nanofiber frameworks for Li metal batteries: the synergistic effect of conductivity and lithiophilic-sites.

Yang, Zhen / Li, Zheng / Liu, Yanqi / Song, Zhaohai / Gao, Zhihao / Zhang, Jianmin / Zheng, Zongmin

Nanotechnology

2022 Volume 33, Issue 35

Abstract: The utilization of carbon framework to guide the growth of the Li dendrites is an important theme for Li metal batteries. The conductivity and electronegative sites of carbon materials will greatly affect the nucleation of Li metal. However, how much ... ...

Abstract	The utilization of carbon framework to guide the growth of the Li dendrites is an important theme for Li metal batteries. The conductivity and electronegative sites of carbon materials will greatly affect the nucleation of Li metal. However, how much these two contributing factors affect the Li plating/stripping stability should be considered. This work presents N, O doped carbon nanofiber framework (CNF) membrane as the interlayer for protecting the Li anode. The amounts of N and O elements and their ratios, the conductivity, the thickness of CNF membrane and their effects on the Li plating/stripping process have been fully analyzed. The voltage profile and the stability of Li plating/stripping process are evaluated by symmetric and asymmetrical coin cells. The lithiophilic heteroatom doped surface mainly works as an excellent guide during the Li plating process, whereas the conductivity and mechanical stability of CNF equalize the current density and confine the volume change in during cycling. With the optimized CNF membrane as the interlayer, both Li metal and Li-S full cells exhibit good capacity properties and cyclic stability.
Language	English
Publishing date	2022-06-14
Publishing country	England
Document type	Journal Article
ZDB-ID	1362365-5
ISSN	1361-6528 ; 0957-4484
ISSN (online)	1361-6528
ISSN	0957-4484
DOI	10.1088/1361-6528/ac73a5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Luteolin induces apoptosis by impairing mitochondrial function and targeting the intrinsic apoptosis pathway in gastric cancer cells.

Ma, Jun / Pan, Zhaohai / Du, Hongchao / Chen, Xiaojie / Zhu, Xuejie / Hao, Wenjin / Zheng, Qiusheng / Tang, Xuexi

Oncology letters

2023 Volume 26, Issue 2, Page(s) 327

Abstract: Gastric cancer is one of the most lethal cancers worldwide. Research has focused on exploring natural medicines to improve the systematic chemotherapy for gastric cancer. Luteolin, a natural flavonoid, possesses anticancer activities. Nevertheless, the ... ...

Abstract	Gastric cancer is one of the most lethal cancers worldwide. Research has focused on exploring natural medicines to improve the systematic chemotherapy for gastric cancer. Luteolin, a natural flavonoid, possesses anticancer activities. Nevertheless, the mechanism of the anticancer effects of luteolin is still not clear. The present study aimed to verify the inhibitory effect of luteolin on gastric cancer HGC-27, MFC and MKN-45 cells and to explore the underlying mechanism. A Cell Counting Kit-8 cell viability assay, flow cytometry, western blot, an ATP content assay and an enzyme activity testing assay were used. Luteolin inhibited the proliferation of gastric cancer HGC-27, MFC and MKN-45 cells. Further, it impaired mitochondrial integrity and function by destroying the mitochondrial membrane potential, downregulating the activities of mitochondrial electron transport chain complexes (mainly complexes I, III and V), and unbalancing the expression of B cell lymphoma-2 family member proteins, eventually leading to apoptosis of gastric cancer HGC-27, MFC and MKN-45 cells. The intrinsic apoptosis pathway was involved in luteolin's anti-gastric cancer effects. Furthermore, mitochondria were the main target in luteolin-induced gastric cancer apoptosis. The present study may provide a theoretical basis for the research on the effect of luteolin on the mitochondrial metabolism in cancer cells, and pave the way for its practical application in the future.
Language	English
Publishing date	2023-06-13
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2573196-8
ISSN	1792-1082 ; 1792-1074
ISSN (online)	1792-1082
ISSN	1792-1074
DOI	10.3892/ol.2023.13913
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Article: Daphnoretin induces reactive oxygen species-mediated apoptosis in melanoma cells.

Wang, Hui / Hu, Xue / Li, Minjing / Pan, Zhaohai / Li, Defang / Zheng, Qiusheng

Oncology letters

2021 Volume 21, Issue 6, Page(s) 453

Abstract: Research suggests that daphnoretin exhibits a diverse array of antitumor mechanisms and pharmacological activities. However, there is no definitive explanation for the antitumor mechanisms of daphnoretin in malignant melanoma. In the present study, MTT ... ...

Abstract	Research suggests that daphnoretin exhibits a diverse array of antitumor mechanisms and pharmacological activities. However, there is no definitive explanation for the antitumor mechanisms of daphnoretin in malignant melanoma. In the present study, MTT and colony formation assays demonstrated that daphnoretin significantly inhibited the proliferation of melanoma A375 and B16 cells. Following treatment with daphnoretin, apoptotic bodies were observed in A375 and B16 cells via Hoechst 33258 staining. Furthermore, western blot analysis revealed that the apoptosis-related proteins cleaved caspase-3, cleaved caspase-9, Bax, cytochrome
Language	English
Publishing date	2021-04-08
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2573196-8
ISSN	1792-1082 ; 1792-1074
ISSN (online)	1792-1082
ISSN	1792-1074
DOI	10.3892/ol.2021.12714
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Article: The Anti-tumor Effects of

Hu, Xue / Yang, Zihui / Liu, Wenjing / Pan, Zhaohai / Zhang, Xin / Li, Minjing / Liu, Xiaona / Zheng, Qiusheng / Li, Defang

Frontiers in oncology

2020 Volume 10, Page(s) 558414

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2020-10-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2020.558414
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Article: Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction.

Zheng, Zhaohai / Yu, Zhangjie / Xu, Buyun / Zhou, Yan / Xing, Yangbo / Li, Qingsong / Tang, Weiliang / Peng, Fang

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 8630480

Abstract: Background: The clinical treatment of coronary microvascular dysfunction (CMD) is mainly based on conventional medicine, but the mechanism of the medicine is single and the efficacy is different. Shenmai injection (SMI) has a variety of ingredients, but ...

Abstract	Background: The clinical treatment of coronary microvascular dysfunction (CMD) is mainly based on conventional medicine, but the mechanism of the medicine is single and the efficacy is different. Shenmai injection (SMI) has a variety of ingredients, but the effect of SMI on CMD has not been studied. This study investigated the effect of SMI on CMD and its possible mechanism. Methods: The protective effect of SMI on CMD was evaluated in Sprague-Dawley (SD) rats and human umbilical vein endothelial cells (HUVECs). In vivo, forty-five male SD rats were randomly divided into control group (sham group), CMD group (model group), and SMI group (treatment group). Two weeks after SMI intervention, laurate was injected into the left ventricle of rats to construct a CMD model. Blood samples were collected to detect myocardial enzymes, oxidative stress, and inflammatory factors, and the hearts of rats were extracted for histopathological staining and western blot detection. In vitro, a hydrogen peroxide-induced endothelial injury model was established in HUVECs. After pretreatment with SMI, cell viability, oxidative stress, vasodilative factors, and apoptosis were detected. Results: In vivo, pretreatment with SMI could effectively reduce the concentrations of lactate dehydrogenase (LDH), creatine kinase-MB (CK-MB), cardiac troponin I (cTnI), endothelin-1 (ET-1), tumor necrosis factor alpha (TNF- Conclusions: Pretreatment with SMI could improve CMD by alleviating oxidative stress, inflammatory response, and apoptosis and then improving vascular endothelial function and microvascular structure.
Language	English
Publishing date	2022-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/8630480
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Article ; Online: Pretreatment with Shenmai Injection Protects against Coronary Microvascular Dysfunction

Zhaohai Zheng / Zhangjie Yu / Buyun Xu / Yan Zhou / Yangbo Xing / Qingsong Li / Weiliang Tang / Fang Peng

Evidence-Based Complementary and Alternative Medicine, Vol

2022 Volume 2022

Abstract: Background. The clinical treatment of coronary microvascular dysfunction (CMD) is mainly based on conventional medicine, but the mechanism of the medicine is single and the efficacy is different. Shenmai injection (SMI) has a variety of ingredients, but ... ...

Abstract	Background. The clinical treatment of coronary microvascular dysfunction (CMD) is mainly based on conventional medicine, but the mechanism of the medicine is single and the efficacy is different. Shenmai injection (SMI) has a variety of ingredients, but the effect of SMI on CMD has not been studied. This study investigated the effect of SMI on CMD and its possible mechanism. Methods. The protective effect of SMI on CMD was evaluated in Sprague-Dawley (SD) rats and human umbilical vein endothelial cells (HUVECs). In vivo, forty-five male SD rats were randomly divided into control group (sham group), CMD group (model group), and SMI group (treatment group). Two weeks after SMI intervention, laurate was injected into the left ventricle of rats to construct a CMD model. Blood samples were collected to detect myocardial enzymes, oxidative stress, and inflammatory factors, and the hearts of rats were extracted for histopathological staining and western blot detection. In vitro, a hydrogen peroxide-induced endothelial injury model was established in HUVECs. After pretreatment with SMI, cell viability, oxidative stress, vasodilative factors, and apoptosis were detected. Results. In vivo, pretreatment with SMI could effectively reduce the concentrations of lactate dehydrogenase (LDH), creatine kinase-MB (CK-MB), cardiac troponin I (cTnI), endothelin-1 (ET-1), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and malondialdehyde (MDA) in the serum of rats. Meanwhile, the expression of bcl-2-associated X (Bax) and caspase-3 protein in the myocardium of rats was decreased in the SMI group. The levels of nitric oxide (NO) and superoxide dismutase (SOD) and the expression of B-cell lymphoma-2 (Bcl-2) were higher in the SMI group than in the CMD group. Pathological staining results showed that SMI could effectively reduce inflammatory infiltration and the formation of collagen fibers and microthrombus in the rat myocardium. In vitro, intervention with SMI could improve endothelial function in a dose-dependent manner ...
Keywords	Other systems of medicine ; RZ201-999
Subject code	610
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Catheter Ablation Versus Medical Therapy for Atrial Fibrillation in Patients with Heart failure: A Meta-Analysis of Randomized Controlled Trials.

Yu, Zhangjie / Xing, Yangbo / Peng, Jiahao / Xu, Buyun / Qi, Ying / Zheng, Zhaohai / Qiu, Yinyin / Qiu, Feiyan / Peng, Fang

Anatolian journal of cardiology

2022 Volume 26, Issue 9, Page(s) 685–695

Abstract: Background: The optimal treatments for atrial fibrillation in heart failure patients are controversial. The present study compared the efficacy of catheter ablation and medical therapy in patients with atrial fibrillation and heart failure.: Methods: ...

Abstract	Background: The optimal treatments for atrial fibrillation in heart failure patients are controversial. The present study compared the efficacy of catheter ablation and medical therapy in patients with atrial fibrillation and heart failure. Methods: Pubmed, Embase, Cochrane Library, and Web of Science were searched until January 15, 2022. Randomized controlled trials comparing catheter ablation for atrial fibrillation with medical therapy in patients with atrial fibrillation and heart failure were enrolled. Primary outcome was all-cause mortality. Secondary outcomes included the heart failure hospitalization and the change in left ventricular ejection fraction, 6-minute walk test distance, peak oxygen consumption, and Minnesota Living with Heart Failure questionnaire score. Results: Totally 8 randomized controlled trials involving 1693 patients were included. Compared with medical therapy, catheter ablation significantly reduced all-cause mortality (risk ratios=0.60, 95% Cl: 0.45 to 0.80, P < .001) and hospitalization due to heart failure (risk ratios=0.58, 95% Cl: 0.46 to 0.73, P < .001), improved left ventricular ejection fraction (mean difference=5.25%, 95% CI: 2.78% to 7.71%, P < .001), improved the performance of 6-minute walk test (mean difference=28.83 m, 95% CI: 8.61 to 49.05 m, P=.005), increased peak oxygen consumption (mean difference=3.11 mL/kg/min, 95% CI: 1.04 to 5.18 mL/kg/min, P=.003), and reduced Minnesota Living with Heart Failure score (mean difference=-8.45, 95% CI: -16.28 to -0.62, P=.03). Conclusion: In heart failure patients with atrial fibrillation, catheter ablation provides more benefits over medical therapy in the important clinical outcomes, exercise capacity, and quality of life.
MeSH term(s)	Atrial Fibrillation/drug therapy ; Atrial Fibrillation/therapy ; Catheter Ablation/adverse effects ; Heart Failure/complications ; Heart Failure/therapy ; Humans ; Quality of Life ; Randomized Controlled Trials as Topic ; Stroke Volume ; Treatment Outcome ; Ventricular Function, Left
Language	English
Publishing date	2022-08-18
Publishing country	Turkey
Document type	Journal Article ; Meta-Analysis
ZDB-ID	2278670-3
ISSN	2149-2271 ; 2149-2271
ISSN (online)	2149-2271
ISSN	2149-2271
DOI	10.5152/AnatolJCardiol.2022.1826
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Article ; Online: Luteolin potentiates low-dose oxaliplatin-induced inhibitory effects on cell proliferation in gastric cancer by inducing G

Ma, Jun / Chen, Xiaojie / Zhu, Xuejie / Pan, Zhaohai / Hao, Wenjin / Li, Defang / Zheng, Qiusheng / Tang, Xuexi

Oncology letters

2021 Volume 23, Issue 1, Page(s) 16

Abstract: Although the reduction of oxaliplatin doses may alleviate deleterious side effects of gastrointestinal and gynecological cancer treatment, it also limits the anticancer therapeutic effects. As a high-efficient and low-priced herbal medicine ingredient, ... ...

Abstract	Although the reduction of oxaliplatin doses may alleviate deleterious side effects of gastrointestinal and gynecological cancer treatment, it also limits the anticancer therapeutic effects. As a high-efficient and low-priced herbal medicine ingredient, luteolin is an agent with a broad spectrum of anticancer activities and acts as a potential enhancer of therapeutic effects of chemotherapy agents in cancer treatment. This study focused on the antitumor effects and mechanism of combined treatment with luteolin and oxaliplatin on a mouse forestomach carcinoma (MFC) cell line. The study used CCK-8 assay, flow cytometry, Annexin V-FITC/PI double staining assay, reactive oxygen species testing assay, mitochondrial membrane potential testing assay, and western blot assay. The results showed that luteolin and oxaliplatin exerted synergistic effects on inhibiting MFC cell proliferation by inducing G
Language	English
Publishing date	2021-11-12
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2573196-8
ISSN	1792-1082 ; 1792-1074
ISSN (online)	1792-1082
ISSN	1792-1074
DOI	10.3892/ol.2021.13134
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Article: Effect of Musk Tongxin Dropping Pill on Myocardial Remodeling and Microcirculation Dysfunction in Diabetic Cardiomyopathy.

Zhao, Jingjing / Zhou, Yan / Liu, Huahua / Zheng, Zhaohai / Liu, Shuqing / Peng, Jiahao / Guo, Hangyuan / Tang, Weiliang / Peng, Fang

Evidence-based complementary and alternative medicine : eCAM

2021 Volume 2021, Page(s) 6620564

Abstract: Objective: To explore the effect of Musk Tongxin Dropping Pill (MTDP) on myocardial remodeling and microcirculation dysfunction in diabetic cardiomyopathy (DCM).: Methods: Forty male SD rats were randomly divided into control group (control group, !## ...

Abstract	Objective: To explore the effect of Musk Tongxin Dropping Pill (MTDP) on myocardial remodeling and microcirculation dysfunction in diabetic cardiomyopathy (DCM). Methods: Forty male SD rats were randomly divided into control group (control group, Results: Compared with control group, blood glucose in other three groups was higher. Left ventricular end systolic diameter (LVSD) and left ventricular end diastolic diameter (LVDD) in DCM group showed a significant increase, while left ventricular ejection fraction (LVEF) and heart rate (HR) in this group displayed an obvious decrease ( Conclusions: MTDP might show a positive effect on myocardial remodeling and microcirculation dysfunction in DCM rats.
Language	English
Publishing date	2021-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2021/6620564
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 5995: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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