LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 10

Search options

  1. Article ; Online: Should emergency medical service stuff use respirators with filtered valve in COVID-19 pandemic?

    Barycka, Katarzyna / Dzieciątkowski, Tomasz / Drozd, Anna / Szarpak, Łukasz / Jaguszewski, Miłosz J / Filipiak, Krzysztof J

    Advances in respiratory medicine

    2021  Volume 88, Issue 6, Page(s) 638–639

    Abstract: Performing medical procedures with the use of personal protective equipment may reduce the efficiency of medical procedures performed, for example, as with the current use of respiratory protection devices, including N95 or surgical masks. Healthcare ... ...

    Abstract Performing medical procedures with the use of personal protective equipment may reduce the efficiency of medical procedures performed, for example, as with the current use of respiratory protection devices, including N95 or surgical masks. Healthcare workers (HCWs) using N95 respirators or medical masks may experience discomfort associated with wearing a mask when performing medical procedures, in particular those associated with increased physical activity, causing increased respiratory effort.
    MeSH term(s) COVID-19/prevention & control ; Emergency Medical Services ; Humans ; Infection Control/methods ; Masks/standards ; N95 Respirators/standards ; Occupational Exposure/prevention & control
    Language English
    Publishing date 2021-01-13
    Publishing country Poland
    Document type Letter
    ZDB-ID 2893877-X
    ISSN 2543-6031 ; 2451-4934
    ISSN (online) 2543-6031
    ISSN 2451-4934
    DOI 10.5603/ARM.a2020.0167
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Risk of self-contamination among healthcare workers in the COVID-19 pandemic.

    Barycka, Katarzyna / Torlinski, Tomasz / Filipiak, Krzysztof Jerzy / Jaguszewski, Milosz / Nadolny, Klaudiusz / Szarpak, Lukasz

    The American journal of emergency medicine

    2020  Volume 46, Page(s) 751–752

    MeSH term(s) COVID-19/epidemiology ; COVID-19/transmission ; Disease Transmission, Infectious/prevention & control ; Health Personnel ; Humans ; Pandemics ; Personal Protective Equipment ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2020.09.055
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2005: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Risk of self-contamination among healthcare workers in the COVID-19 pandemic

    Barycka, Katarzyna / Torlinski, Tomasz / Filipiak, Krzysztof Jerzy / Jaguszewski, Milosz / Nadolny, Klaudiusz / Szarpak, Lukasz

    Am. j. emerg. med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #798971
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Risk of self-contamination among healthcare workers in the COVID-19 pandemic.

    Barycka, Katarzyna / Torlinski, Tomasz / Filipiak, Krzysztof Jerzy / Jaguszewski, Milosz / Nadolny, Klaudiusz / Szarpak, Lukasz

    2020  

    Keywords WD400 Emergency medicine ; covid19
    Language English
    Publishing date 2020-09-28
    Publisher Elsevier
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Risk of self-contamination among healthcare workers in the COVID-19 pandemic

    Barycka, Katarzyna / Torlinski, Tomasz / Filipiak, Krzysztof Jerzy / Jaguszewski, Milosz / Nadolny, Klaudiusz / Szarpak, Lukasz

    The American Journal of Emergency Medicine ; ISSN 0735-6757

    2020  

    Keywords Emergency Medicine ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.ajem.2020.09.055
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Comparative effectiveness of N95 respirators and surgical/face masks in preventing airborne infections in the era of SARS-CoV2 pandemic: A meta-analysis of randomized trials.

    Barycka, Katarzyna / Szarpak, Lukasz / Filipiak, Krzysztof Jerzy / Jaguszewski, Milosz / Smereka, Jacek / Ladny, Jerzy Robert / Turan, Oguz

    PloS one

    2020  Volume 15, Issue 12, Page(s) e0242901

    Abstract: Background: Recently, several randomized controlled trials (RCTs) have evaluated the effect of N95 respirators compared with medical masks to protect against acute respiratory infections. However, these studies are limited by modest sample sizes and ... ...

    Abstract Background: Recently, several randomized controlled trials (RCTs) have evaluated the effect of N95 respirators compared with medical masks to protect against acute respiratory infections. However, these studies are limited by modest sample sizes and inconclusive results. Therefore, the goal of the present study was to review the relevant and available published RCTs with the aid of the increased power of meta-analytic methods in order to assess the effectiveness of medical masks and N95 respirators in reducing the risk of respiratory infections.
    Methods: This meta-analysis follows the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement for conducting and reporting results. We searched PubMed, Web of Science, Embase, and Cochrane databases from inception through April 1, 2020 to identify potentially relevant studies. Two authors (LS and JS) independently searched the titles and abstracts of the potentially eligible articles. They independently retrieved required data from the eligible trials; the data were initially tabulated for statistical analysis. Two authors (JRL and LS) independently assessed the methodological quality of the included RCTs using the Cochrane Collaboration's tool for assessing risk of bias.
    Results: Six articles met the inclusion criteria. The pooled analysis showed that N95 respirators did not reduce the risk of infection with respiratory viruses compared with medical/surgical masks (5.7% vs. 7.9%; RR = 1.12; 95% CI: 0.88-1.41; p = 0.36); however, there was no statistically significant difference in laboratory-confirmed influenza between N95 and medical masks (RR = 0.91; 95% CI: 0.77-1.07; p = 0.26). Medical masks provided similar protection against other viruses, including coronavirus (RR = 0.74; 95% CI: 0.32-1.73; p = 0.49). Respiratory illness, as well as influenza-like illness were less frequently observed with N95 respirators.
    Conclusions: Our meta-analysis suggests that there are insufficient data to definitively determine whether N95 respirators are superior to medical masks in protection against transmissible acute respiratory infections. Further randomized trials are necessary to compare the above methods of respiratory protection in the context of COVID-19 incidence.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Health Personnel ; Humans ; Infection Control/methods ; N95 Respirators ; Occupational Exposure/prevention & control ; Pandemics ; Randomized Controlled Trials as Topic ; Respiratory Protective Devices ; Respiratory Tract Infections/prevention & control ; Respiratory Tract Infections/virology ; SARS-CoV-2/pathogenicity
    Language English
    Publishing date 2020-12-15
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0242901
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Comparative effectiveness of N95 respirators and surgical/face masks in preventing airborne infections in the era of SARS-CoV2 pandemic

    Katarzyna Barycka / Lukasz Szarpak / Krzysztof Jerzy Filipiak / Milosz Jaguszewski / Jacek Smereka / Jerzy Robert Ladny / Oguz Turan

    PLoS ONE, Vol 15, Iss 12, p e

    A meta-analysis of randomized trials.

    2020  Volume 0242901

    Abstract: Background Recently, several randomized controlled trials (RCTs) have evaluated the effect of N95 respirators compared with medical masks to protect against acute respiratory infections. However, these studies are limited by modest sample sizes and ... ...

    Abstract Background Recently, several randomized controlled trials (RCTs) have evaluated the effect of N95 respirators compared with medical masks to protect against acute respiratory infections. However, these studies are limited by modest sample sizes and inconclusive results. Therefore, the goal of the present study was to review the relevant and available published RCTs with the aid of the increased power of meta-analytic methods in order to assess the effectiveness of medical masks and N95 respirators in reducing the risk of respiratory infections. Methods This meta-analysis follows the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement for conducting and reporting results. We searched PubMed, Web of Science, Embase, and Cochrane databases from inception through April 1, 2020 to identify potentially relevant studies. Two authors (LS and JS) independently searched the titles and abstracts of the potentially eligible articles. They independently retrieved required data from the eligible trials; the data were initially tabulated for statistical analysis. Two authors (JRL and LS) independently assessed the methodological quality of the included RCTs using the Cochrane Collaboration's tool for assessing risk of bias. Results Six articles met the inclusion criteria. The pooled analysis showed that N95 respirators did not reduce the risk of infection with respiratory viruses compared with medical/surgical masks (5.7% vs. 7.9%; RR = 1.12; 95% CI: 0.88-1.41; p = 0.36); however, there was no statistically significant difference in laboratory-confirmed influenza between N95 and medical masks (RR = 0.91; 95% CI: 0.77-1.07; p = 0.26). Medical masks provided similar protection against other viruses, including coronavirus (RR = 0.74; 95% CI: 0.32-1.73; p = 0.49). Respiratory illness, as well as influenza-like illness were less frequently observed with N95 respirators. Conclusions Our meta-analysis suggests that there are insufficient data to definitively determine whether N95 respirators are superior to medical masks in protection against transmissible acute respiratory infections. Further randomized trials are necessary to compare the above methods of respiratory protection in the context of COVID-19 incidence.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Online: Should emergency medical service stuff use respirators with filtered valve in COVID-19 pandemic?

    Barycka, Katarzyna / Dzieciątkowski, Tomasz / Drozd, Anna / Szarpak, Łukasz / Jaguszewski, Miłosz J / Filipiak, Krzysztof J

    Advances in Respiratory Medicine; Ahead of Print

    2015  

    Abstract: Performing medical procedures with the use of personal protective equipment may reduce the efficiency of medical procedures performed, for example, as with the current use of respiratory protection devices, including N95 or surgical masks. Healthcare ... ...

    Abstract Performing medical procedures with the use of personal protective equipment may reduce the efficiency of medical procedures performed, for example, as with the current use of respiratory protection devices, including N95 or surgical masks. Healthcare workers (HCWs) using N95 respirators or medical masks may experience discomfort associated with wearing a mask when performing medical procedures, in particular those associated with increased physical activity, causing increased respiratory effort.
    Keywords airway protector ; respirators ; medical masks ; filtered valve ; safety ; COVID-19 ; SARS-CoV-2 ; covid19
    Language English
    Publishing date 2015-03-18
    Publisher Via Medica
    Publishing country pl
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: 1-desoxy analog of 2MD: synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3.

    Sibilska, Izabela / Barycka, Katarzyna M / Sicinski, Rafal R / Plum, Lori A / Deluca, Hector F

    The Journal of steroid biochemistry and molecular biology

    2010  Volume 121, Issue 1-2, Page(s) 51–55

    Abstract: During our ongoing structure-activity studies in the vitamin D area, we obtained (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (5). This analog, designated 2MD, is characterized by a significantly enhanced calcemic activity and is currently ... ...

    Abstract During our ongoing structure-activity studies in the vitamin D area, we obtained (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (5). This analog, designated 2MD, is characterized by a significantly enhanced calcemic activity and is currently evaluated as a potential drug for osteoporosis. Therefore, it was of interest to synthesize also its 1-desoxy analog and to evaluate its biological action. These studies were aimed at solving an intriguing problem: can such a vitamin also be hydroxylated in vivo at the allylic C-1 position despite lack of the exomethylene moiety at C-10? The Wittig-Horner coupling of the known protected (20S)-25-hydroxy Grundmann ketone 17 and the phosphine oxides 16 and 33, differing in their hydroxyls protection, provided the target 1-desoxy-2MD (6) after removal of the silyl protecting groups. Two synthetic paths have been elaborated leading to the desired A-ring synthons and starting from commercially available compounds: 1,4-cyclohexanedione monoethylene acetal (7) and (-)-quinic acid (19). The biological activity in vitro of the synthesized 1-desoxy-2MD (6) was evaluated and this analog was found to have an affinity for the vitamin D receptor (VDR) similar as its parent compound 2MD (5) while being much less active in the transcriptional assay. The results of the biological tests in vivo are also discussed.
    MeSH term(s) Animals ; Binding, Competitive ; Calcitriol/analogs & derivatives ; Calcitriol/chemical synthesis ; Calcitriol/pharmacology ; Drug Design ; Drug Evaluation, Preclinical/methods ; HL-60 Cells ; Humans ; Male ; Oxides/chemistry ; Phosphines/chemistry ; Rats ; Rats, Sprague-Dawley ; Receptors, Calcitriol/chemistry ; Recombinant Proteins/chemistry ; Transcription, Genetic
    Chemical Substances 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 ; 25-hydroxy-2-methylene-19-norvitamin D3 ; Oxides ; Phosphines ; Receptors, Calcitriol ; Recombinant Proteins ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2010-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1049188-0
    ISSN 1879-1220 ; 0960-0760
    ISSN (online) 1879-1220
    ISSN 0960-0760
    DOI 10.1016/j.jsbmb.2010.03.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 708: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Diaminobutane (DAB) dendrimers are potent binders of oral phosphate.

    Williams, Katie B / Barycka, Katarzyna / Zella, Julia B / DeLuca, Hector F

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

    2009  Volume 24, Issue 1, Page(s) 97–101

    Abstract: Reduction of blood phosphorus is a critical component in the management of secondary hyperparathyroidism in chronic kidney disease patients. In addition to dialysis treatment and dietary phosphorus restriction, oral phosphate binders are often consumed ... ...

    Abstract Reduction of blood phosphorus is a critical component in the management of secondary hyperparathyroidism in chronic kidney disease patients. In addition to dialysis treatment and dietary phosphorus restriction, oral phosphate binders are often consumed with meals to reduce the availability of food phosphorus. Several oral phosphate binders are approved for use in chronic kidney disease patients, but all have practical limitations because of toxicity, poor efficacy, or high cost. Using an in vivo method to measure intestinal phosphate absorption in rats using radiolabeled phosphate, we found that first-, second-, third-, and fifth-generation diaminobutane dendrimer compounds, DAB-4-Cl, DAB-8-Cl, DAB-16-Cl, and DAB-64-Cl, respectively, drastically reduce the absorption of inorganic phosphate in a dose-dependent manner. To avoid complications of metabolic acidosis caused by hydrochloride salts, an acetate salt, DAB-9-AcOH, was prepared and shown to be equally effective at binding radiolabeled phosphate as DAB-8-Cl. DAB-8-AcOH was further shown to increase fecal phosphorus and decrease serum phosphorus in a dose-dependent manner when fed to rats. These data suggest that dendrimer compounds are of great potential use in the binding of food phosphate for the management of hyperparathyroidism secondary to chronic kidney disease.
    MeSH term(s) Administration, Oral ; Animals ; Butanes/chemistry ; Butanes/pharmacology ; Chelating Agents/pharmacology ; Dendrimers/chemistry ; Dose-Response Relationship, Drug ; Hyperparathyroidism/metabolism ; Kidney Diseases/metabolism ; Male ; Phosphate-Binding Proteins/chemistry ; Phosphates/chemistry ; Phosphates/metabolism ; Phosphorus/blood ; Phosphorus/chemistry ; Polyamines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sevelamer
    Chemical Substances Butanes ; Chelating Agents ; Dendrimers ; Phosphate-Binding Proteins ; Phosphates ; Polyamines ; Phosphorus (27YLU75U4W) ; Sevelamer (9YCX42I8IU)
    Language English
    Publishing date 2009-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632783-7
    ISSN 1523-4681 ; 0884-0431
    ISSN (online) 1523-4681
    ISSN 0884-0431
    DOI 10.1359/jbmr.080819
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2142: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top