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  1. Article ; Online: Awakening Ptosis: A Video Case Series.

    Kennedy, Brandon J / Desautels, Jordan D / Warner, Judith E A / Patel, Bhupendra C

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2024  

    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000002110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1670: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  2. Article: Risks Posed to Corneal Transplant Recipients by COVID-19-Affected Donors.

    Desautels, Jordan D / Moshirfar, Majid / Martheswaran, Tanisha / Shmunes, Kathryn M / Ronquillo, Yasmyne C

    Ophthalmology and therapy

    2020  Volume 9, Issue 3, Page(s) 371–379

    Abstract: The recent emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resultant human disease, COVID-19, will likely have a significant impact on the corneal tissue donor pool. Current recommendations from the United ... ...

    Abstract The recent emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resultant human disease, COVID-19, will likely have a significant impact on the corneal tissue donor pool. Current recommendations from the United States and global eye bank associations call for the outright avoidance of tissues from donors recently infected with or exposed to COVID-19. This conservative recommendation is currently appropriate given the reported ocular sequelae, tear film viral detectability, and transmissibility of COVID-19. However, the rapidly increasing global prevalence and mortality of COVID-19 threatens the tenability of current tissue exclusion guidelines, and may necessitate their relaxation in the near future.
    Keywords covid19
    Language English
    Publishing date 2020-05-06
    Publishing country England
    Document type Journal Article
    ISSN 2193-8245
    ISSN 2193-8245
    DOI 10.1007/s40123-020-00254-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A Contemporary Risk Analysis of Iatrogenic Transmission of Creutzfeldt-Jakob Disease (CJD) via Corneal Transplantation in the United States.

    Martheswaran, Tanisha / Desautels, Jordan D / Moshirfar, Majid / Shmunes, Kathryn M / Ronquillo, Yasmyne C / Hoopes, Phillip C

    Ophthalmology and therapy

    2020  Volume 9, Issue 3, Page(s) 465–483

    Abstract: Background: Creutzfeldt-Jakob disease (CJD) is a rare, fatal, neurodegenerative prion disease potentially transmissible through corneal transplantation. While statistical analyses performed two decades ago estimated the overall prevalence of CJD in the ... ...

    Abstract Background: Creutzfeldt-Jakob disease (CJD) is a rare, fatal, neurodegenerative prion disease potentially transmissible through corneal transplantation. While statistical analyses performed two decades ago estimated the overall prevalence of CJD in the corneal donor pool to be low, the recent significant increase in corneal transplants performed and deaths due to CJD in the U.S. warrants a contemporary risk analysis.
    Methods: A literature review was conducted to determine the overall number of globally reported cases of CJD transmission through corneal transplantation. U.S. mortality and cornea donation data were utilized to estimate the age-stratified prevalence of undiagnosed, latent CJD in the cornea donor pool in 2018. A historical statistical analysis was performed to estimate the number of corneas from donors with latent CJD entering the U.S. donor pool for each year between 1979 and 2018. From these statistical analyses, risk factors of iatrogenic transmission were identified and summarized.
    Results: Ten reported cases of iatrogenic transmission of CJD through corneal transplants were identified globally. In 2018, an estimated 3.8 corneas from donors with undiagnosed latent CJD potentially entered the pool of 111,703 transplant-intended corneas harvested from individuals aged 31-80. Between 1979 and 2018, an estimated 47 corneas may have entered the U.S. transplant-intended pool from donors with latent CJD aged 35 to 84. The advanced age of donors and a history of multiple transplants in recipients were both prominent risk factors for iatrogenic transmission.
    Conclusions: The 10 reported global cases of iatrogenic transmission likely under-represent the number of individuals with a coinciding history of death by CJD and prior corneal transplantation, as supported by our statistical analysis and lack of geographical diversity of reported cases. As effective screening methods develop and globalization of cornea transplantation broadens, it is of utmost importance that cornea transplantation history among victims of CJD should be investigated and reported.
    Language English
    Publishing date 2020-06-20
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2193-8245
    ISSN 2193-8245
    DOI 10.1007/s40123-020-00272-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Risks Posed to Corneal Transplant Recipients by COVID-19-Affected Donors

    Desautels, Jordan D. / Moshirfar, Majid / Martheswaran, Tanisha / Shmunes, Kathryn M. / Ronquillo, Yasmyne C.

    Ophthalmology and Therapy

    2020  Volume 9, Issue 3, Page(s) 371–379

    Keywords Ophthalmology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ISSN 2193-8245
    DOI 10.1007/s40123-020-00254-w
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article: Corneal Hydrops Secondary to Intrastromal Corneal Ring Intrusion into the Anterior Chamber 7 Years after Implantation: A Case Report.

    Moshirfar, Majid / Bean, Andrew E / Desautels, Jordan D / Birdsong, Orry C

    Ophthalmology and therapy

    2017  Volume 6, Issue 2, Page(s) 373–379

    Abstract: Introduction: This report describes the first known case of late-onset intrusion of an intrastromal ring segment into the anterior chamber due to posterior migration of a ring segment. To our knowledge, intrastromal ring segment penetration has only ... ...

    Abstract Introduction: This report describes the first known case of late-onset intrusion of an intrastromal ring segment into the anterior chamber due to posterior migration of a ring segment. To our knowledge, intrastromal ring segment penetration has only been shown to occur in the intraoperative or immediate postoperative period. We postulate that the perforation in this case is due to progressive thinning of the cornea, possibly in combination with habitual eye rubbing.
    Case report: A 44-year-old man presented with acute corneal hydrops related to penetration of Descemet's membrane and endothelium by an intrastromal ring segment implanted 7 years prior. Removal of the ring segment resulted in an anterior chamber fistula that directed fluid through the ring segment tunnel to the ocular surface. Leakage of aqueous humor was successfully controlled, and corneal edema gradually resolved.
    Conclusion: This case indicates the need for long term monitoring of ring segment proximity to the posterior corneal surface, especially in patients with ectatic ocular conditions and/or habitual eye rubbing behavior.
    Language English
    Publishing date 2017-08-28
    Publishing country England
    Document type Journal Article
    ISSN 2193-8245
    ISSN 2193-8245
    DOI 10.1007/s40123-017-0105-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Risks Posed to Corneal Transplant Recipients by COVID-19-Affected Donors

    Desautels, Jordan D / Moshirfar, Majid / Martheswaran, Tanisha / Shmunes, Kathryn M / Ronquillo, Yasmyne C

    Abstract: The recent emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resultant human disease, COVID-19, will likely have a significant impact on the corneal tissue donor pool. Current recommendations from the United ... ...

    Abstract The recent emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resultant human disease, COVID-19, will likely have a significant impact on the corneal tissue donor pool. Current recommendations from the United States and global eye bank associations call for the outright avoidance of tissues from donors recently infected with or exposed to COVID-19. This conservative recommendation is currently appropriate given the reported ocular sequelae, tear film viral detectability, and transmissibility of COVID-19. However, the rapidly increasing global prevalence and mortality of COVID-19 threatens the tenability of current tissue exclusion guidelines, and may necessitate their relaxation in the near future.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #186349
    Database COVID19

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  7. Article: Stereoacuity after small aperture corneal inlay implantation.

    Linn, Steven H / Skanchy, David F / Quist, Tyler S / Desautels, Jordan D / Moshirfar, Majid

    Clinical ophthalmology (Auckland, N.Z.)

    2017  Volume 11, Page(s) 233–235

    Abstract: Purpose: The aim of this study was to compare stereoacuity before and after KAMRA corneal inlay implantation for the correction of presbyopia.: Patients and methods: This is a prospective study of 60 patients who underwent KAMRA inlay implantation. ... ...

    Abstract Purpose: The aim of this study was to compare stereoacuity before and after KAMRA corneal inlay implantation for the correction of presbyopia.
    Patients and methods: This is a prospective study of 60 patients who underwent KAMRA inlay implantation. Patients were examined before and 6 months after surgery for stereoacuity, uncorrected distance visual acuity (UDVA), and uncorrected near visual acuity (UNVA).
    Results: The mean stereoacuity before surgery was 29.5±28.1 arcsec (range: 20-200) and at 6 months was 29.8±26.4 arcsec (range: 20-200). The decline in stereoacuity was not statistically significant. At 6 months follow-up, UDVA was 20/25 or better in all 60 patients and UNVA was J2 (20/25) or better in 51 (85%) patients.
    Conclusion: There is no significant change in stereoacuity following KAMRA inlay implantation. The KAMRA inlay is a good treatment option for improving near vision in presbyopic patients while preserving stereoacuity and distance vision.
    Language English
    Publishing date 2017-01-24
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1177-5467
    ISSN 1177-5467
    DOI 10.2147/OPTH.S124101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Case of Presumed Transient Light-Sensitivity Syndrome After Small-Incision Lenticule Extraction.

    Desautels, Jordan D / Moshirfar, Majid / Quist, Tyler S / Skanchy, David F / Hoopes, Phillip C

    Cornea

    2017  Volume 36, Issue 9, Page(s) 1139–1140

    Abstract: Purpose: To report the first presumed case of transient light-sensitivity syndrome (TLSS) after small-incision lenticule extraction (SMILE).: Methods: A 27-year-old male patient was treated for severe photophobic symptoms occurring 7 weeks after ... ...

    Abstract Purpose: To report the first presumed case of transient light-sensitivity syndrome (TLSS) after small-incision lenticule extraction (SMILE).
    Methods: A 27-year-old male patient was treated for severe photophobic symptoms occurring 7 weeks after undergoing a bilateral SMILE procedure. His comprehensive ocular examination was unremarkable and his visual acuity was unaffected. Treatment was a month-long tapering dose of topical steroids.
    Results: Photophobic symptoms fully resolved after steroid treatment. TLSS related to SMILE mirrors TLSS after laser in situ keratomileusis in both onset and steroid responsiveness.
    Conclusions: TLSS is a rare and minor complication of SMILE. Photophobic symptoms associated with post-SMILE TLSS are fully responsive to topical corticosteroids.
    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000001240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1790: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Neodymium:YAG laser posterior capsulotomy in eye with an intrastromal inlay.

    Hoopes, Phillip C / Desautels, Jordan D / Moshirfar, Majid / Linn, Steven H / Mamalis, Nick

    Journal of cataract and refractive surgery

    2017  Volume 43, Issue 5, Page(s) 699–702

    Abstract: We report intraoperative issues, patient outcomes, and lessons learned from inadvertently contacting a Kamra corneal inlay with a neodymium:YAG (Nd:YAG) laser during a routine capsulotomy procedure for posterior capsule opacification. We also present ... ...

    Abstract We report intraoperative issues, patient outcomes, and lessons learned from inadvertently contacting a Kamra corneal inlay with a neodymium:YAG (Nd:YAG) laser during a routine capsulotomy procedure for posterior capsule opacification. We also present scanning electron microscopic and histopathologic images from a series of 4 inlays implanted in postmortem porcine eyes that were purposely contacted with an Nd:YAG laser. Our capsulotomy patient developed a clinically insignificant and transient corneal opacity accompanied by mild blanching on the inlay. Modeling this scenario in porcine corneas demonstrated the potential for carbon particle liberation into the overlying stroma, damage to the inlay body, and fusion of inlay nutrition holes.
    MeSH term(s) Animals ; Cataract Extraction ; Humans ; Laser Therapy ; Lasers, Solid-State ; Lens Implantation, Intraocular ; Neodymium ; Posterior Capsulotomy/methods ; Swine
    Chemical Substances Neodymium (2I87U3734A)
    Language English
    Publishing date 2017-06-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1016/j.jcrs.2017.04.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1806: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article: Comparison of FDA safety and efficacy data for KAMRA and Raindrop corneal inlays.

    Moshirfar, Majid / Desautels, Jordan D / Wallace, Ryan T / Koen, Nicholas / Hoopes, Phillip C

    International journal of ophthalmology

    2017  Volume 10, Issue 9, Page(s) 1446–1451

    Abstract: Aim: To provide a side-by-side analysis of the summary of safety and effectiveness data (SSED) submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.: Methods: SSED reports submitted to the FDA for KAMRA and ... ...

    Abstract Aim: To provide a side-by-side analysis of the summary of safety and effectiveness data (SSED) submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.
    Methods: SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity (CDVA), adverse event rates, induction of astigmatism, retention of contrast sensitivity, stability of manifest refractive spherical equivalent (MRSE), and achieved monocular uncorrected near visual acuity (UNVA) at 24mo.
    Results: Totally 442/508 of KAMRA patients and 344/373 Raindrop patients remained enrolled in the clinical trials at 24mo. The proportion of KAMRA and Raindrop patients who lost ≥2 lines of CDVA at 24mo was 3.4% and 1%, respectively. The adverse event rate was comparable between the devices. No significant inductions of astigmatism were noted. Both technologies induced a transient myopic shift in MRSE followed by a hyperopic shift and subsequent stabilization. Totally 87% of KAMRA and 98% of Raindrop patients attained a monocular UNVA of J5 (20/40) or better at 24mo, 28% of KAMRA and 67% of Raindrop patients attained a monocular UNVA of J1 (20/20) or better at 24mo.
    Conclusion: Both devices can be considered safe and effective, however, the results of corneal inlay implantation are mixed, and long-term patient satisfaction will likely depend on subjective expectations about the capabilities of the inlays. Variability in surgical technique and postoperative care within and between the two clinical trials diminishes the comparative power of this article.
    Language English
    Publishing date 2017-09-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2663246-9
    ISSN 2227-4898 ; 2222-3959
    ISSN (online) 2227-4898
    ISSN 2222-3959
    DOI 10.18240/ijo.2017.09.18
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