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  1. Article ; Online: Improving outcomes in glomerular disease.

    Kronbichler, Andreas / Jones, Rachel B

    Nature reviews. Nephrology

    2021  Volume 18, Issue 2, Page(s) 82–83

    MeSH term(s) Glomerular Filtration Rate ; Glomerulonephritis/therapy ; Humans ; Kidney Diseases/therapy
    Language English
    Publishing date 2021-12-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/s41581-021-00526-z
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    Zs.A 6334: Show issues Location:
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  2. Article ; Online: Treating Obsessive Compulsive Disorder in Adolescents and Adults with Down Syndrome: Results from a Scoping Rapid Review.

    Fodstad, Jill C / Russell, Rachel / Bullington, Molly / Jones, Lauren B / Iticovici, Micah / Meudt, Emily

    Journal of autism and developmental disorders

    2024  

    Abstract: Purpose: Adolescents and adults with Down syndrome are noted to display symptoms and behaviors consistent with a diagnosis of Obsessive Compulsive Disorder. While evidenced-based interventions, including psychopharmacology and therapeutic interventions ... ...

    Abstract Purpose: Adolescents and adults with Down syndrome are noted to display symptoms and behaviors consistent with a diagnosis of Obsessive Compulsive Disorder. While evidenced-based interventions, including psychopharmacology and therapeutic interventions including exposure and response prevention, exist and effectively treat obsessive-compulsive symptoms in neurotypical populations, less is known about effective treatments for similar presentations in persons with Down syndrome.
    Methods: A scoping rapid review was conducted in April 2023 to determine what treatments are being used to target obsessive-compulsive symptoms and related behaviors in adolescents and adults with Down syndrome, the quality of those treatments, and their alignment with current evidenced-based interventions.
    Results: A total of eleven articles, all single case or case series, published between 1992 and 2017 were identified describing the treatment of 32 adolescents and adults with Down syndrome and obsessive-compulsive traits and behaviors including: hoarding, cleaning, gross motor compulsions, and food, hygiene, dressing, and checking rituals. Interventions used most often aligned with evidenced-based guidelines for treating obsessive compulsive disorder and included psychopharmacology, psychotherapy, and complementary and alternative medicine.
    Conclusions: While the outcomes of most interventions yielded partial or significant reduction in symptoms, poor research quality and limited generalizability noted across all studies make it difficult to inform guidelines for caring for this high-needs population. In the future, we believe it is necessary to perform more rigorous research focused on treating obsessive compulsive symptoms in individuals with Down syndrome with sufficient follow-up to fully assess treatment effectiveness.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-024-06336-z
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    Zs.A 765: Show issues Location:
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  3. Article ; Online: Glomerular basement membrane nephritis: crescentic renal inflammation and immunosuppressive intervention in the time of the severe acute respiratory syndrome coronavirus 2 pandemic.

    Brix, Silke R / Jones, Rachel B / Jayne, David R W

    Kidney international

    2021  Volume 99, Issue 5, Page(s) 1234–1235

    MeSH term(s) Basement Membrane ; COVID-19 ; Glomerular Basement Membrane ; Glomerulonephritis ; Humans ; Inflammation ; Nephritis ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.02.004
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    Zs.A 797: Show issues Location:
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  4. Article ; Online: Pregnancy following rituximab for orbital eosinophilic angiocentric fibrosis.

    Mansfield Smith, Sonja C / Clare, Gerry / Jones, Rachel B

    Rheumatology (Oxford, England)

    2021  Volume 60, Issue Suppl 3, Page(s) iii57–iii59

    MeSH term(s) Adult ; Eosinophilia/complications ; Eosinophilia/drug therapy ; Eosinophilia/pathology ; Female ; Fibrosis ; Glucocorticoids/administration & dosage ; Humans ; Immunologic Factors/administration & dosage ; Orbit/pathology ; Orbital Diseases/drug therapy ; Orbital Diseases/etiology ; Orbital Diseases/pathology ; Prednisolone/administration & dosage ; Pregnancy ; Rituximab/administration & dosage
    Chemical Substances Glucocorticoids ; Immunologic Factors ; Rituximab (4F4X42SYQ6) ; Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 2021-06-17
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keab034
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    Zs.MO 497: Show issues

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  5. Article ; Online: Therapeutic dilemmas in relapsing renal ANCA-associated vasculitis.

    Suchanek, Ondrej / Jayne, David R W / Jones, Rachel B

    Rheumatology (Oxford, England)

    2021  Volume 60, Issue Suppl 3, Page(s) iii60–iii62

    MeSH term(s) Acute Kidney Injury/drug therapy ; Acute Kidney Injury/immunology ; Aged ; Anti-Inflammatory Agents/administration & dosage ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/complications ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/drug therapy ; Humans ; Immunologic Factors/administration & dosage ; Male ; Prednisolone/administration & dosage ; Recurrence ; Rituximab/administration & dosage
    Chemical Substances Anti-Inflammatory Agents ; Immunologic Factors ; Rituximab (4F4X42SYQ6) ; Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 2021-06-17
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keab178
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  6. Article ; Online: A Current View of SARS-CoV-2 Vaccine Policies Amongst Pediatric Renal Transplant Centers and Relationships to State Policy.

    Littlejohn, James B / Pace, Rachel L / Curtis, Kyle L / Jones-Carr, Maggie E / Koller, Felicitas L

    The American surgeon

    2023  Volume 89, Issue 8, Page(s) 3594–3596

    Abstract: Given its mortality benefit, renal transplantation remains the ideal treatment modality for end stage renal disease in children. Despite the recent expansion of use in young children, the novel SARS-CoV-2 vaccine has not been universally accepted. ... ...

    Abstract Given its mortality benefit, renal transplantation remains the ideal treatment modality for end stage renal disease in children. Despite the recent expansion of use in young children, the novel SARS-CoV-2 vaccine has not been universally accepted. Similarly, vaccine related state regulations are heterogenous. We present a cross-sectional analysis of institutional specific vaccination policies at US pediatric renal transplant centers and relationships to state legislation. We found that 36.1% of institutions require COVID-19 vaccination prior to transplant, while 17 states have current legislation prohibiting proof of vaccination as a means of access to public services. Of the 63.9% of transplant centers without immunization requirement, almost two-thirds are located in states without prohibitory regulations. Despite an unclear primary influence of institutional policy, our study demonstrates a lack of standardization and potential to create unnecessary inequities.
    MeSH term(s) Child ; Humans ; Child, Preschool ; COVID-19 Vaccines ; Kidney Transplantation ; Cross-Sectional Studies ; COVID-19/prevention & control ; SARS-CoV-2 ; Policy ; Transplant Recipients
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348231157895
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    Uk I Zs.106: Show issues Location:
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  7. Article ; Online: Response to: 'MYCYC, unravelling the long road ahead in ANCA-associated vasculitis' by Jain

    Harper, Lorraine / Jones, Rachel B

    Annals of the rheumatic diseases

    2019  Volume 79, Issue 5, Page(s) e58

    MeSH term(s) Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis ; Antibodies, Antineutrophil Cytoplasmic ; Cyclophosphamide ; Humans ; Mycophenolic Acid ; Remission Induction
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic ; Cyclophosphamide (8N3DW7272P) ; Mycophenolic Acid (HU9DX48N0T)
    Language English
    Publishing date 2019-03-20
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2019-215254
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    Uh III Zs.114: Show issues Location:
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    Zs.MO 167: Show issues

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  8. Article ; Online: Outcomes of total hip and knee arthroplasty in patients with haemophilia: A meta-analysis of comparative studies and clinical practice recommendations.

    Challoumas, Dimitris / Munn, David / Jeyakumar, Gowsikan / Bagot, Catherine / Rodgers, Ryan / Kearns, Rachel / Jones, Bryn

    Haemophilia : the official journal of the World Federation of Hemophilia

    2023  Volume 30, Issue 1, Page(s) 180–194

    Abstract: ... 1.9)], 1-year revision/re-operation [OR 1.4 CI (1.2, 1.8)] and b) THA: major and minor 90-day ...

    Abstract Aim: We aimed to compare the outcomes of total hip and knee arthroplasty (THA, TKA) in haemophilic patients compared to matched controls.
    Methods: Through a literature search we identified all cohort studies comparing perioperative complications and other outcomes of THA and TKA in haemophilic patients and matched controls without haemophilia. Results of the same outcome measure assessed by two or more studies were pooled in meta-analyses; odds ratios (ORs) with 95% confidence intervals (CI) were calculated. The risk of bias in included studies and certainty of evidence of each result were assessed using the Newcastle-Ottawa scale and the GRADE tool respectively.
    Results: A total of five retrospective studies with matched controls were included; four of them were of good and one of fair quality. Based on moderate certainty evidence, compared to matched controls, patients with haemophilia had a significantly higher incidence of the following complications after a) TKA: periprosthetic joint infection [PJI; OR 1.6 CI (1.3, 1.9)], 1-year revision/re-operation [OR 1.4 CI (1.2, 1.8)] and b) THA: major and minor 90-day complications [major OR 2.2 CI (1.7, 2.9); minor OR 1.4 CI (1.1, 1.8)], venous thromboembolism [OR 3.1 CI (2.1, 4.6)]. PJI incidence in THA was not different in haemophilia compared to controls [OR 1.5 CI (.9, 2.6)].
    Conclusion: Our results can be used by healthcare professionals counselling patients with haemophilia considering a THA or TKA as part of the informed consent process. We provide detailed clinical recommendations for the perioperative management of THA and TKA in haemophilic patients.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Knee/adverse effects ; Arthroplasty, Replacement, Hip/adverse effects ; Hemophilia A/complications ; Retrospective Studies ; Knee Joint ; Risk Factors
    Language English
    Publishing date 2023-12-11
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.14904
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  9. Article ; Online: Aggressive vasculitis after lung transplantation for cystic fibrosis.

    Loudon, Kevin W / Parmar, Jasvir / Jayne, David R W / Jones, Rachel B

    Rheumatology (Oxford, England)

    2021  Volume 60, Issue Suppl 3, Page(s) iii47–iii49

    MeSH term(s) Adult ; Cystic Fibrosis/surgery ; Humans ; Lung Transplantation ; Male ; Postoperative Complications ; Vasculitis
    Language English
    Publishing date 2021-06-17
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/keab041
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  10. Article ; Online: Feasibility of daily pain measurement using text messages in hidradenitis suppurativa clinical trials; data from the THESEUS study.

    Hasan, Samar B / Bates, Janine / Cannings-John, Rebecca / Collier, Fiona / Evans, Judith / Gibbons, Angela / Harris, Ceri / Howells, Laura / Hood, Kerenza / Howes, Rachel / Leighton, Paul / Riaz, Muhammad / Rodrigues, Jeremy / Stanton, Helen / Thomas, Kim S / Thomas-Jones, Emma / Ingram, John R

    The British journal of dermatology

    2024  Volume 190, Issue 5, Page(s) 775–777

    MeSH term(s) Humans ; Hidradenitis Suppurativa/drug therapy ; Pain Measurement ; Text Messaging ; Feasibility Studies ; Quality of Life
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1093/bjd/ljae057
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