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  1. Book ; Online: Sustainable Development Goal 3 : Health and Well-being of Ageing in Hong Kong

    Fong, Ben Y. F. / Law, Vincent T. S. / Leung, Tiffany C. H. / Lo, Man Fung / Ng, Tommy K. C. / Yee, Hilary H. L.

    2022  

    Keywords Development economics & emerging economies ; Public health & preventive medicine ; Child & developmental psychology ; Ageing and Diversity ; Healthy Ageing ; Health Equity ; Health Inequalities ; Sustainable Development Goals
    Size 1 electronic resource (104 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021232884
    ISBN 9781032115016 ; 1032115017
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Telemedicine in internal medicine: A statement by the European Federation of Internal Medicine.

    Filomena, Pietrantonio / Sebastian, Kuhn / Kati, Kärberg / Tiffany, Leung / Ismael, Said-Criado

    European journal of internal medicine

    2023  Volume 112, Page(s) 138–139

    MeSH term(s) Humans ; Telemedicine ; Internal Medicine
    Language English
    Publishing date 2023-03-03
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2023.02.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Screening for Anxiety in Adolescent and Adult Women.

    Leung, Tiffany I / Cifu, Adam S / Lee, Wei Wei

    JAMA

    2022  Volume 327, Issue 10, Page(s) 976–977

    MeSH term(s) Adolescent ; Adult ; Anxiety/diagnosis ; Anxiety Disorders/diagnosis ; Anxiety Disorders/drug therapy ; Female ; Humans ; Mass Screening/standards ; Practice Guidelines as Topic ; Pregnancy
    Language English
    Publishing date 2022-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2022.1647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Models (CREMLS).

    El Emam, Khaled / Leung, Tiffany I / Malin, Bradley / Klement, William / Eysenbach, Gunther

    Journal of medical Internet research

    2024  Volume 26, Page(s) e52508

    Abstract: The number of papers presenting machine learning (ML) models that are being submitted to and published in the Journal of Medical Internet Research and other JMIR Publications journals has steadily increased. Editors and peer reviewers involved in the ... ...

    Abstract The number of papers presenting machine learning (ML) models that are being submitted to and published in the Journal of Medical Internet Research and other JMIR Publications journals has steadily increased. Editors and peer reviewers involved in the review process for such manuscripts often go through multiple review cycles to enhance the quality and completeness of reporting. The use of reporting guidelines or checklists can help ensure consistency in the quality of submitted (and published) scientific manuscripts and, for example, avoid instances of missing information. In this Editorial, the editors of JMIR Publications journals discuss the general JMIR Publications policy regarding authors' application of reporting guidelines and specifically focus on the reporting of ML studies in JMIR Publications journals, using the Consolidated Reporting of Machine Learning Studies (CREMLS) guidelines, with an example of how authors and other journals could use the CREMLS checklist to ensure transparency and rigor in reporting.
    MeSH term(s) Machine Learning ; Humans ; Guidelines as Topic ; Prognosis ; Checklist
    Language English
    Publishing date 2024-05-02
    Publishing country Canada
    Document type Editorial
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/52508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: SCN4A

    Chan, Tina Yee-Ching / Hung, Ling-Yin / Lam, Tiffany Yan-Lok / Sheng, Bun / Leung, Frank Ying-Kit / Lee, Hencher Han-Chih

    Heliyon

    2023  Volume 10, Issue 1, Page(s) e23663

    Abstract: ... ...

    Abstract SCN4A
    Language English
    Publishing date 2023-12-11
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e23663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Protection afforded by previous Vibrio cholerae infection against subsequent disease and infection: A review.

    Leung, Tiffany / Matrajt, Laura

    PLoS neglected tropical diseases

    2021  Volume 15, Issue 5, Page(s) e0009383

    Abstract: Background: Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139 that is associated with a high global burden.: Methods: We analyzed the estimated duration of immunity following cholera infection from available published studies. ...

    Abstract Background: Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139 that is associated with a high global burden.
    Methods: We analyzed the estimated duration of immunity following cholera infection from available published studies. We searched PubMed and Web of Science for studies of the long-term immunity following cholera infection. We identified 22 eligible studies and categorized them as either observational, challenge, or serological.
    Results: We found strong evidence of protection at 3 years after infection in observational and challenge studies. However, serological studies show that elevated humoral markers of potential correlates of protection returned to baseline within 1 year. Additionally, a subclinical cholera infection may confer lower protection than a clinical one, as suggested by 3 studies that found that, albeit with small sample sizes, most participants with a subclinical infection from an initial challenge with cholera had a symptomatic infection when rechallenged with a homologous biotype.
    Conclusions: This review underscores the need to elucidate potential differences in the protection provided by clinical and subclinical cholera infections. Further, more studies are warranted to bridge the gap between the correlates of protection and cholera immunity. Understanding the duration of natural immunity to cholera can help guide control strategies and policy.
    MeSH term(s) Adolescent ; Adult ; Antibodies, Bacterial/blood ; Antibodies, Bacterial/immunology ; Child ; Child, Preschool ; Cholera/immunology ; Cholera/prevention & control ; Cholera Toxin/immunology ; Cross Protection/immunology ; Humans ; Immunologic Memory/immunology ; Infant ; Lipopolysaccharides/immunology ; Middle Aged ; Vibrio cholerae O1/immunology ; Vibrio cholerae O139/immunology ; Young Adult
    Chemical Substances Antibodies, Bacterial ; Lipopolysaccharides ; Cholera Toxin (9012-63-9)
    Language English
    Publishing date 2021-05-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0009383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The impact of lowering the study design significance threshold to 0.005 on sample size in randomized cancer clinical trials

    Tiffany H. Leung / James C. Ho / Xiaofei Wang / Wendy W. Lam / Herbert H. Pang

    Journal of Clinical and Translational Science, Vol

    2024  Volume 8

    Abstract: The proposal of improving reproducibility by lowering the significance threshold to 0.005 has been discussed, but the impact on conducting clinical trials has yet to be examined from a study design perspective. The impact on sample size and study ... ...

    Abstract The proposal of improving reproducibility by lowering the significance threshold to 0.005 has been discussed, but the impact on conducting clinical trials has yet to be examined from a study design perspective. The impact on sample size and study duration was investigated using design setups from 125 phase II studies published between 2015 and 2022. The impact was assessed using percent increase in sample size and additional years of accrual with the medians being 110.97% higher and 2.65 years longer respectively. The results indicated that this proposal causes additional financial burdens that reduce the efficiency of conducting clinical trials.
    Keywords P-value ; threshold ; trial design ; clinical trial ; sample size ; Medicine ; R
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Brilliant Ideas Can Come in All Sizes: Research Letters.

    Kukafka, Rita / Leung, Tiffany I / Eysenbach, Gunther

    Journal of medical Internet research

    2022  Volume 24, Issue 7, Page(s) e41046

    Abstract: The Journal of Medical Internet Research is pleased to offer "Research Letter" as a new article type. Research Letters are similar to original and short paper types in that they report the original results of studies in a peer-reviewed, structured ... ...

    Abstract The Journal of Medical Internet Research is pleased to offer "Research Letter" as a new article type. Research Letters are similar to original and short paper types in that they report the original results of studies in a peer-reviewed, structured scientific communication. The Research Letter article type is optimal for presenting new, early, or sometimes preliminary research findings, including interesting observations from ongoing research with significant implications that justify concise and rapid communication.
    MeSH term(s) Biomedical Research ; Communication ; Humans ; Peer Review ; Publishing
    Language English
    Publishing date 2022-07-26
    Publishing country Canada
    Document type Editorial
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/41046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Can AI Mitigate Bias in Writing Letters of Recommendation?

    Leung, Tiffany I / Sagar, Ankita / Shroff, Swati / Henry, Tracey L

    JMIR medical education

    2023  Volume 9, Page(s) e51494

    Abstract: Letters of recommendation play a significant role in higher education and career progression, particularly for women and underrepresented groups in medicine and science. Already, there is evidence to suggest that written letters of recommendation contain ...

    Abstract Letters of recommendation play a significant role in higher education and career progression, particularly for women and underrepresented groups in medicine and science. Already, there is evidence to suggest that written letters of recommendation contain language that expresses implicit biases, or unconscious biases, and that these biases occur for all recommenders regardless of the recommender's sex. Given that all individuals have implicit biases that may influence language use, there may be opportunities to apply contemporary technologies, such as large language models or other forms of generative artificial intelligence (AI), to augment and potentially reduce implicit biases in the written language of letters of recommendation. In this editorial, we provide a brief overview of existing literature on the manifestations of implicit bias in letters of recommendation, with a focus on academia and medical education. We then highlight potential opportunities and drawbacks of applying this emerging technology in augmenting the focused, professional task of writing letters of recommendation. We also offer best practices for integrating their use into the routine writing of letters of recommendation and conclude with our outlook for the future of generative AI applications in supporting this task.
    Language English
    Publishing date 2023-08-23
    Publishing country Canada
    Document type Editorial
    ISSN 2369-3762
    ISSN 2369-3762
    DOI 10.2196/51494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Protection afforded by previous Vibrio cholerae infection against subsequent disease and infection

    Tiffany Leung / Laura Matrajt

    PLoS Neglected Tropical Diseases, Vol 15, Iss 5, p e

    A review.

    2021  Volume 0009383

    Abstract: Background Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139 that is associated with a high global burden. Methods We analyzed the estimated duration of immunity following cholera infection from available published studies. We ... ...

    Abstract Background Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139 that is associated with a high global burden. Methods We analyzed the estimated duration of immunity following cholera infection from available published studies. We searched PubMed and Web of Science for studies of the long-term immunity following cholera infection. We identified 22 eligible studies and categorized them as either observational, challenge, or serological. Results We found strong evidence of protection at 3 years after infection in observational and challenge studies. However, serological studies show that elevated humoral markers of potential correlates of protection returned to baseline within 1 year. Additionally, a subclinical cholera infection may confer lower protection than a clinical one, as suggested by 3 studies that found that, albeit with small sample sizes, most participants with a subclinical infection from an initial challenge with cholera had a symptomatic infection when rechallenged with a homologous biotype. Conclusions This review underscores the need to elucidate potential differences in the protection provided by clinical and subclinical cholera infections. Further, more studies are warranted to bridge the gap between the correlates of protection and cholera immunity. Understanding the duration of natural immunity to cholera can help guide control strategies and policy.
    Keywords Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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