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  1. Article: Why India's nationally representative surveys need to look beyond gender normativity.

    Dutta, Sritama / Singh, Sneha / Rehman, Tanveer / Kanungo, Srikanta / Pati, Sanghamitra

    BMJ global health

    2023  Volume 8, Issue 8

    MeSH term(s) Humans ; India ; Gender Identity ; Surveys and Questionnaires
    Language English
    Publishing date 2023-08-27
    Publishing country England
    Document type Journal Article
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2023-012920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: PCy

    Hazarika, Roktopol / Dutta, Sanghamitra / Sarmah, Samprity / Hazarika, Priyanuj Krishnann / Singh, Kuldeep / Kumar, Arvind / Sarma, Bipul / Sarma, Diganta

    Organic & biomolecular chemistry

    2024  Volume 22, Issue 4, Page(s) 694–698

    Abstract: An approach towards Cu-free click chemistry has been developed in this work. Silver-catalyzed ... ...

    Abstract An approach towards Cu-free click chemistry has been developed in this work. Silver-catalyzed PCy
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob01738a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Classical molecular dynamics simulation identifies catechingallate as a promising antiviral polyphenol against MPOX palmitoylated surface protein.

    Mishra, Sarbani / Rout, Madhusmita / Singh, Mahender Kumar / Dehury, Budheswar / Pati, Sanghamitra

    Computational biology and chemistry

    2024  Volume 110, Page(s) 108070

    Abstract: Cumulative global prevalence of the emergent monkeypox (MPX) infection in the non-endemic countries has been professed as a global public health predicament. Lack of effective MPX-specific treatments sets the baseline for designing the current study. ... ...

    Abstract Cumulative global prevalence of the emergent monkeypox (MPX) infection in the non-endemic countries has been professed as a global public health predicament. Lack of effective MPX-specific treatments sets the baseline for designing the current study. This research work uncovers the effective use of known antiviral polyphenols against MPX viral infection, and recognises their mode of interaction with the target F13 protein, that plays crucial role in formation of enveloped virions. Herein, we have employed state-of-the-art machine learning based AlphaFold2 to predict the three-dimensional structure of F13 followed by molecular docking and all-atoms molecular dynamics (MD) simulations to investigate the differential mode of F13-polyphenol interactions. Our extensive computational approach identifies six potent polyphenols Rutin, Epicatechingallate, Catechingallate, Quercitrin, Isoquecitrin and Hyperoside exhibiting higher binding affinity towards F13, buried inside a positively charged binding groove. Intermolecular contact analysis of the docked and MD simulated complexes divulges three important residues Asp
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ISSN 1476-928X
    ISSN (online) 1476-928X
    DOI 10.1016/j.compbiolchem.2024.108070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effect of Surface Topography on the Primary Stability of Miniscrew Implants in Orthodontics-A Systematic Review and Meta-Analysis.

    Singh, Shivani / Sahoo, Nivedita / Jena, Sanghamitra / Mohanty, Pritam / Dash, Bhagabati P / Meher, Jasbir

    Journal of pharmacy & bioallied sciences

    2024  Volume 16, Issue Suppl 1, Page(s) S78–S82

    Abstract: This present study has the purpose of determining how surface topography of implants affects the initial stability of miniscrew implants (MSIs). Electronic databases like PubMed Central, Scopus, Web of Science, Embase, and Cochrane Library, as well as ... ...

    Abstract This present study has the purpose of determining how surface topography of implants affects the initial stability of miniscrew implants (MSIs). Electronic databases like PubMed Central, Scopus, Web of Science, Embase, and Cochrane Library, as well as reference lists, were thoroughly searched up until September 2022. Clinical trials involving individuals who got anchorage through mini-implants, along with information on categories of mini-implants dimension, shape, thread design, and insertion site, were required as part of the eligibility criteria. Primary and secondary stability were also assessed. We carried out selection process for the study, extraction of data, quality assessment, and a meta-analysis. The qualitative synthesis included 10 papers: three randomized, four prospective, and four retrospective clinical investigations. The results of this meta-analysis demonstrate that the clinical state of MIs is controlled by their geometrical surface qualities, which are also influenced by their shape and thread design. According to the evidence this meta-analysis produced, this circumstance exists. The duration of the follow-up period and MI success rates did not correlate with one another.
    Language English
    Publishing date 2024-02-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.jpbs_906_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Recalcitrant skin ulcers in a patient with Papillon-Lefèvre syndrome: an unusual novel presentation.

    Malhi, Kittu / Singh, Sukhdeep / Mustari, Akash P / Bishnoi, Anuradha / Machhua, Sanghamitra / Jindal, Ankur Kumar

    Clinical and experimental dermatology

    2023  Volume 49, Issue 5, Page(s) 512–513

    MeSH term(s) Humans ; Papillon-Lefevre Disease/complications ; Skin Ulcer/pathology ; Skin Ulcer/etiology ; Female ; Male
    Language English
    Publishing date 2023-11-07
    Publishing country England
    Document type Case Reports ; Letter ; Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llad446
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  6. Article ; Online: Seasonal variations in respiratory morbidity in primary care and its correlation with the quality of air in urban Odisha, India.

    Sinha, Abhinav / Pritam, Jitendriya Amrit / Jain, Hitesh Kumar / Giri, Sidhartha / Pati, Sanghamitra / Kshatri, Jaya Singh

    PLOS global public health

    2024  Volume 4, Issue 1, Page(s) e0002313

    Abstract: Poor air quality, especially in urban regions among low-and middle-income countries such as India poses a significant healthcare challenge. Amongst urban areas, metropolitan cities garner the utmost importance for air quality related policies and studies ...

    Abstract Poor air quality, especially in urban regions among low-and middle-income countries such as India poses a significant healthcare challenge. Amongst urban areas, metropolitan cities garner the utmost importance for air quality related policies and studies with limited studies from tier II cities which are thought to be relatively immune to air pollution. Hence, we aimed to identify the most frequent respiratory morbidities and explore its correlation with exposure to ambient PM2.5 particles in Bhubaneswar (a tier II city in coastal India), Odisha. A chart review was carried out through data extracted from the records of urban health centres. Data on PM2.5 concentrations were obtained from Odisha State Pollution Control Board. The morbidities were coded by using the International Classification of Primary Care‑2 system (ICPC-2). Descriptive statistics such as incidence of respiratory illnesses was computed across seasons. The ecological correlation between respiratory morbidity patterns and corresponding concentration of PM2.5 in air was analysed for each season. A positive correlation (r = o.94) between PM2.5 and respiratory morbidities was observed. The incidence of respiratory morbidities was 183.31 per 1000 person year. We identified 21 out of 43 respiratory diseases classified under ICPC-2. Upper Respiratory Tract Infection was the most commonly (116.8 per 1000 person year) incident condition. We observed one-fourth increase in the incidence of respiratory illnesses during winters. Respiratory morbidities are common in urban Bhubaneswar which follows a seasonal pattern and are possibly linked with the seasonal variations in levels of PM2.5 particles. Our study highlights that tier II cities are equally prone to health effects of air pollution. Future programmes and policies should take these cities into consideration too.
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0002313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: All-atoms molecular dynamics study to screen potent efflux pump inhibitors against KpnE protein of

    Dey, Suchanda / Rout, Madhusmita / Pati, Sanghamitra / Singh, Mahender Kumar / Dehury, Budheswar / Subudhi, Enketeswara

    Journal of biomolecular structure & dynamics

    2023  Volume 42, Issue 7, Page(s) 3492–3506

    Abstract: The Small Multidrug Resistance efflux pump protein KpnE, plays a pivotal role in multi-drug resistance ... ...

    Abstract The Small Multidrug Resistance efflux pump protein KpnE, plays a pivotal role in multi-drug resistance in
    MeSH term(s) Molecular Dynamics Simulation ; Klebsiella pneumoniae ; Molecular Docking Simulation ; Escherichia coli/metabolism ; Lipid Bilayers/chemistry ; Antiporters/metabolism ; Escherichia coli Proteins/metabolism
    Chemical Substances Lipid Bilayers ; EmrE protein, E coli (147995-06-0) ; Antiporters ; Escherichia coli Proteins
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2214232
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  8. Article: Burden and determinants of multimorbidity among women in reproductive age group: a cross-sectional study based in India.

    Puri, Parul / Kothavale, Ajinkya / Singh, S K / Pati, Sanghamitra

    Wellcome open research

    2021  Volume 5, Page(s) 275

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-02-18
    Publishing country England
    Document type Journal Article
    ISSN 2398-502X
    ISSN 2398-502X
    DOI 10.12688/wellcomeopenres.16398.2
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  9. Article: Disparities in Coverage of Adult Immunization among Older Adults in India.

    Singh, Damini / Sinha, Abhinav / Kanungo, Srikanta / Pati, Sanghamitra

    Vaccines

    2022  Volume 10, Issue 12

    Abstract: A lack of a universal adult immunization scheme in India poses a challenge to achieve universal health coverage. Healthcare disparity is one of the biggest challenges in low- and middle-income countries such as India. We aimed to estimate the disparities ...

    Abstract A lack of a universal adult immunization scheme in India poses a challenge to achieve universal health coverage. Healthcare disparity is one of the biggest challenges in low- and middle-income countries such as India. We aimed to estimate the disparities in coverage of various adult vaccines among older adults in India using nationally representative data. An observational analysis among 31,464 participants aged ≥60 years from the Longitudinal Ageing Study in India, 2017-2018, was conducted. Vaccination coverage across wealth quintiles and selected non-communicable diseases were reported as frequencies and weighted proportions along with their 95% confidence intervals as a measure of uncertainty. The highest coverage was of the diphtheria and tetanus vaccine (2.75%) followed by typhoid (1.84%), hepatitis B (1.82%), influenza (1.59%), and pneumococcal (0.74%). The most affluent groups had a higher coverage of all vaccines. Participants having high cholesterol, psychiatric conditions, and cancer had the highest coverage of all vaccines. Overall, a very low coverage of all vaccines was observed. The coverage was influenced by social determinants of health, depicting a disparity in accessing immunization. Hence, at-risk groups such as the deprived and multimorbid patients need to be covered under the ambit of free immunization to achieve universal health coverage.
    Language English
    Publishing date 2022-12-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10122124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Identifying non-communicable disease multimorbidity patterns and associated factors: a latent class analysis approach.

    Puri, Parul / Singh, Shri Kant / Pati, Sanghamitra

    BMJ open

    2022  Volume 12, Issue 7, Page(s) e053981

    Abstract: Objective: In the absence of adequate nationally-representative empirical evidence on multimorbidity, the existing healthcare delivery system is not adequately oriented to cater to the growing needs of the older adult population. Therefore, the present ... ...

    Abstract Objective: In the absence of adequate nationally-representative empirical evidence on multimorbidity, the existing healthcare delivery system is not adequately oriented to cater to the growing needs of the older adult population. Therefore, the present study identifies frequently occurring multimorbidity patterns among older adults in India. Further, the study examines the linkages between the identified patterns and socioeconomic, demographic, lifestyle and anthropometric correlates.
    Design: The present findings rest on a large nationally-representative sample from a cross-sectional study.
    Setting and participants: The study used data on 58 975 older adults (45 years and older) from the Longitudinal Ageing Study in India, 2017-2018.
    Primary and secondary outcome measures: The study incorporated a list of 16 non-communicable diseases to identify commonly occurring patterns using latent class analysis. The study employed multinomial logistic regression models to assess the association between identified disease patterns with unit-level socioeconomic, demographic, lifestyle and anthropometric characteristics.
    Results: The present study demonstrates that older adults in the country can be segmented into six patterns: 'relatively healthy', 'hypertension', 'gastrointestinal disorders-hypertension-musculoskeletal disorders', 'musculoskeletal disorders-hypertension-asthma', 'metabolic disorders' and 'complex cardiometabolic disorders'. Additionally, socioeconomic, demographic, lifestyle and anthropometric factors are significantly associated with one or more identified disease patterns.
    Conclusions: The identified classes 'hypertension', 'metabolic disorders' and 'complex cardiometabolic disorders' reflect three stages of cardiometabolic morbidity with hypertension as the first and 'complex cardiometabolic disorders' as the last stage of disease progression. This underscores the need for effective prevention strategies for high-risk hypertension group. Also, targeted interventions are essential to reduce the burden on the high-risk population and provide equitable health services at the community level.
    MeSH term(s) Aged ; Cross-Sectional Studies ; Humans ; Hypertension/epidemiology ; Latent Class Analysis ; Metabolic Diseases ; Multimorbidity ; Musculoskeletal Diseases/epidemiology ; Noncommunicable Diseases/epidemiology
    Language English
    Publishing date 2022-07-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2021-053981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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