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Article ; Online: Importance of numerical density of tubulointerstitium infiltrates in the prognosis of antineutrophil cytoplasmic antibodies-associated glomerulonephritis.

Božić, Dušan / Ljubičić, Bojana / Knežević, Violeta / Ćelić, Dejan / Veselinov, Vladimir

2023 Volume 64, Issue 1, Page(s) 37–44

Abstract: Aim: To examine the association of the numerical density of the tubulointerstitium infiltrate with pathohistological changes in the glomeruli and the estimated glomerular filtration rate (eGFR) at kidney biopsy and after 18 months.: Methods: This ... ...

Abstract	Aim: To examine the association of the numerical density of the tubulointerstitium infiltrate with pathohistological changes in the glomeruli and the estimated glomerular filtration rate (eGFR) at kidney biopsy and after 18 months. Methods: This retrospective study enrolled 44 patients (43.2% male) with antineutrophil cytoplasmic antibodies-associated glomerulonephritis treated at the University Clinical Center of Vojvodina between 2017 and 2020. The numerical density of infiltrates in the tubulointerstitium was determined with the Weibel (M-2) system. Data on biochemical, clinical, and pathohistological parameters were obtained. Results: The mean age was 57.7±10.23 years. Global sclerosis in more than 50% of glomeruli and crescents in more than 50% of glomeruli were significantly associated with a mean lower eGFR (17.6±11.78; 32.0±26.13, respectively) at kidney biopsy (P=0.002; P<0.001, respectively), but not after 18 months. The average numerical density of infiltrates was significantly higher in patients with more than 50% of globally sclerotic glomeruli (P<0.001) and with crescents in more than 50% of glomeruli (P<0.001). The average numerical density of infiltrates significantly correlated with eGFR at biopsy (r=-0.614), but not after 18 months. Our results were confirmed by using multiple linear regression. Conclusion: Numerical density of infiltrates, and global glomerular sclerosis and crescents in more than 50% of glomeruli significantly affect eGFR at biopsy, but not after 18 months.
MeSH term(s)	Humans ; Male ; Middle Aged ; Aged ; Female ; Antibodies, Antineutrophil Cytoplasmic ; Retrospective Studies ; Sclerosis ; Glomerulonephritis ; Prognosis
Chemical Substances	Antibodies, Antineutrophil Cytoplasmic
Language	English
Publishing date	2023-03-03
Publishing country	Croatia
Document type	Journal Article
ZDB-ID	1157623-6
ISSN	1332-8166 ; 0353-9504
ISSN (online)	1332-8166
ISSN	0353-9504
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Article ; Online: Critical Time for Weed Removal in Corn as Influenced by Planting Pattern and PRE Herbicides

Dejan Nedeljković / Stevan Knežević / Dragana Božić / Sava Vrbničanin

Agriculture, Vol 11, Iss 587, p

2021 Volume 587

Abstract: Determining the critical time for weed removal (CTWR) is essential for the development of an integrated weed management plan. Therefore, field experiments were conducted to evaluate the effects of two planting patterns (standard and twin-row) with and ... ...

Abstract	Determining the critical time for weed removal (CTWR) is essential for the development of an integrated weed management plan. Therefore, field experiments were conducted to evaluate the effects of two planting patterns (standard and twin-row) with and without PRE-applied herbicides on CTWR in corn. Experiments were laid out in a split-plot arrangement with two main plots: (i) standard row planting (SRP) that is 70 cm wide, and (ii) twin-row planting (TRP) with 50 cm distance between each set of double rows. Each main plot was divided into two sub-plots (with and without PRE herbicides). The sub-sub-plots consisted of seven weed removal timings for PRE herbicides, and tank mixes were utilized (S-metolachlor (1.44 kg a.i. ha −1 ) + terbutylazine (0.75 kg a.i. ha −1 )). The CTWR without PRE herbicides was similar in both the SRP and TRP systems, where it was around the V1 to V2 (16 to 19 d after emergence (DAE)) growth stages. The use of PRE-applied herbicides delayed CTWR in SRP to the V4 to V10 (25 to 58 DAE) stages and up to the V11 (60 DAE) stage in TRP. These results clearly indicate that PRE herbicides are important for protecting corn yields regardless of the planting pattern. In more meteorologically favorable seasons (sufficient heat and precipitation) in both sowing systems, corn plants produce their biological maximum with the fact that over the number of plants per unit area (SRP = 80,000 plants ha −1 , TRP = 93,900 plants ha −1 ) provide higher yields in variants with PRE herbicides, and thus the advantage of the TRP system can be justified.
Keywords	corn ; CTWC ; planting pattern ; crop density ; grain yield ; PRE herbicides ; Agriculture (General) ; S1-972
Subject code	630
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Angiotensin-Converting Enzyme 2 (ACE2) as a Potential Diagnostic and Prognostic Biomarker for Chronic Inflammatory Lung Diseases.

Marčetić, Dejan / Samaržija, Miroslav / Vukić Dugac, Andrea / Knežević, Jelena

Genes

2021 Volume 12, Issue 7

Abstract: Chronic inflammatory lung diseases are characterized by uncontrolled immune response in the airways as their main pathophysiological manifestation. The lack of specific diagnostic and therapeutic biomarkers for many pulmonary diseases represents a major ... ...

Abstract	Chronic inflammatory lung diseases are characterized by uncontrolled immune response in the airways as their main pathophysiological manifestation. The lack of specific diagnostic and therapeutic biomarkers for many pulmonary diseases represents a major challenge for pulmonologists. The majority of the currently approved therapeutic approaches are focused on achieving disease remission, although there is no guarantee of complete recovery. It is known that angiotensin-converting enzyme 2 (ACE2), an important counter-regulatory component of the renin-angiotensin-aldosterone system (RAAS), is expressed in the airways. It has been shown that ACE2 plays a role in systemic regulation of the cardiovascular and renal systems, lungs and liver by acting on blood pressure, electrolyte balance control mechanisms and inflammation. Its protective role in the lungs has also been presented, but the exact pathophysiological mechanism of action is still elusive. The aim of this study is to review and discuss recent findings about ACE2, including its potential role in the pathophysiology of chronic inflammatory lung diseases:, i.e., chronic obstructive pulmonary disease, asthma, and pulmonary hypertension. Additionally, in the light of the coronavirus 2019 disease (COVID-19), we will discuss the role of ACE2 in the pathophysiology of this disease, mainly represented by different grades of pulmonary problems. We believe that these insights will open up new perspectives for the future use of ACE2 as a potential biomarker for early diagnosis and monitoring of chronic inflammatory lung diseases.
MeSH term(s)	Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Asthma/diagnosis ; Asthma/enzymology ; Asthma/genetics ; COVID-19/enzymology ; COVID-19/genetics ; COVID-19 Testing ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/enzymology ; Hypertension, Pulmonary/genetics ; Inflammation/diagnosis ; Inflammation/enzymology ; Inflammation/genetics ; Lung/enzymology ; Lung/pathology ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/enzymology ; Pulmonary Disease, Chronic Obstructive/genetics ; Renin-Angiotensin System ; SARS-CoV-2/metabolism
Chemical Substances	ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
Language	English
Publishing date	2021-07-09
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes12071054
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Article: Critical Time for Weed Removal in Corn as Influenced by Planting Pattern and PRE Herbicides

Nedeljković, Dejan / Knežević, Stevan / Božić, Dragana / Vrbničanin, Sava

Agriculture (Basel). 2021 June 24, v. 11, no. 7

2021

Abstract	Determining the critical time for weed removal (CTWR) is essential for the development of an integrated weed management plan. Therefore, field experiments were conducted to evaluate the effects of two planting patterns (standard and twin-row) with and without PRE-applied herbicides on CTWR in corn. Experiments were laid out in a split-plot arrangement with two main plots: (i) standard row planting (SRP) that is 70 cm wide, and (ii) twin-row planting (TRP) with 50 cm distance between each set of double rows. Each main plot was divided into two sub-plots (with and without PRE herbicides). The sub-sub-plots consisted of seven weed removal timings for PRE herbicides, and tank mixes were utilized (S-metolachlor (1.44 kg a.i. ha⁻¹) + terbutylazine (0.75 kg a.i. ha⁻¹)). The CTWR without PRE herbicides was similar in both the SRP and TRP systems, where it was around the V1 to V2 (16 to 19 d after emergence (DAE)) growth stages. The use of PRE-applied herbicides delayed CTWR in SRP to the V4 to V10 (25 to 58 DAE) stages and up to the V11 (60 DAE) stage in TRP. These results clearly indicate that PRE herbicides are important for protecting corn yields regardless of the planting pattern. In more meteorologically favorable seasons (sufficient heat and precipitation) in both sowing systems, corn plants produce their biological maximum with the fact that over the number of plants per unit area (SRP = 80,000 plants ha⁻¹, TRP = 93,900 plants ha⁻¹) provide higher yields in variants with PRE herbicides, and thus the advantage of the TRP system can be justified.
Keywords	agriculture ; corn ; heat ; integrated weed management ; metolachlor ; planting ; weeds
Language	English
Dates of publication	2021-0624
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2651678-0
ISSN	2077-0472
ISSN	2077-0472
DOI	10.3390/agriculture11070587
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Fabry disease in Serbia - current status and future perspectives

Ćelić Dejan / Božić Dušan / Ilić Tatjana / Knežević Violeta / Golubović Sonja / Živković Siniša / Ljubičić Bojana / Naumović Radomir / Mitić Igor

Vojnosanitetski Pregled, Vol 79, Iss 11, Pp 1142-

2022 Volume 1148

Abstract: ... ...

Abstract	nema
Keywords	fabry disease ; genetic diseases ; inborn ; diagnosis ; signs and symptoms ; therapeutics ; serbia ; Medicine (General) ; R5-920
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Military Health Department, Ministry of Defance, Serbia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Recognizing the Frequency of Exposure to Cyberbullying in Children: The Results of the National HBSC Study in Serbia.

Kangrga, Milica / Nikolic, Dejan / Santric-Milicevic, Milena / Rakic, Ljiljana / Knezevic, Tatjana / Djuricic, Goran / Stojkovic, Jasna / Radosavljevic, Natasa / Mihajlovic, Sladjana / Medjo, Biljana / Lackovic, Milan

Children (Basel, Switzerland)

2024 Volume 11, Issue 2

Abstract: Nowadays, children are able to enrich their reality via the Internet. Unfortunately, this may increase their risk of becoming victims of cyberbullying. We analyzed the health characteristics and risk behavior of two cohorts of children in Serbia; those ... ...

Abstract	Nowadays, children are able to enrich their reality via the Internet. Unfortunately, this may increase their risk of becoming victims of cyberbullying. We analyzed the health characteristics and risk behavior of two cohorts of children in Serbia; those who reported being exposed to cyberbullying and those who did not. The statistical differences and logistic regression models were applied to the data on 3267 students collected from 64 schools participating in the 2017 Serbian Study on health behavior in school-age children (HBSC). Children exposed to cyberbullying reported having the following health problems on a daily basis: headache (18.5%), back pain (19.5%), depression (21.6%), irritability or bad mood (17.7%), nervousness (16.0%), sleep problems (16.1%), and dizziness (21.2%). As for the different types of risk behavior, cigarette smoking ranging from six to nine days ever was the most prevalent (26.9%). It was followed closely by getting drunk more than 10 times ever (24.1%). Compared to non-victims, victims were found to be at a higher risk of perceived back pain (OR = 2.27), depression (OR = 1.43), irritability or bad mood (OR = 2.07), nervousness (OR = 2.23), and dizziness (OR = 2.43) as well as being injured once or twice (OR = 1.98) or three or more times (OR = 4.09). Victims were associated with further risk factors: having smoked more than five cigarettes ever in life (OR = 1.73) and having gotten drunk two to three times (OR = 1.71) or four or more times (OR = 1.65). As the number of school-age children using social media continues to rise, we must prioritize educating them about self-help and community resources for addressing related health issues with greater speed and intensity. The findings from Serbia suggest that while children may be aware of their health issues, they may be unaware of their link to cyberbullying, which could hinder their ability to address these issues promptly. The respondents' attention to the health implications of cyberbullying could be increased by reformulating the survey questions used in the HBSC study.
Language	English
Publishing date	2024-01-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children11020172
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Article: Genome sequence diversity of SARS-CoV-2 in Serbia: insights gained from a 3-year pandemic study.

Novkovic, Mirjana / Banovic Djeri, Bojana / Ristivojevic, Bojan / Knezevic, Aleksandra / Jankovic, Marko / Tanasic, Vanja / Radojicic, Verica / Keckarevic, Dusan / Vidanovic, Dejan / Tesovic, Bojana / Skakic, Anita / Tolinacki, Maja / Moric, Ivana / Djordjevic, Valentina

Frontiers in microbiology

2024 Volume 15, Page(s) 1332276

Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has been evolving rapidly causing emergence of new variants and health uncertainties. Monitoring the evolution of the virus was of the utmost ... ...

Abstract	The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has been evolving rapidly causing emergence of new variants and health uncertainties. Monitoring the evolution of the virus was of the utmost importance for public health interventions and the development of national and global mitigation strategies. Here, we report national data on the emergence of new variants, their distribution, and dynamics in a 3-year study conducted from March 2020 to the end of January 2023 in the Republic of Serbia. Nasopharyngeal and oropharyngeal swabs from 2,398 COVID-19-positive patients were collected and sequenced using three different next generation technologies: Oxford Nanopore, Ion Torrent, and DNBSeq. In the subset of 2,107 SARS-CoV-2 sequences which met the quality requirements, detection of mutations, assignment to SARS-CoV-2 lineages, and phylogenetic analysis were performed. During the 3-year period, we detected three variants of concern, namely, Alpha (5.6%), Delta (7.4%), and Omicron (70.3%) and one variant of interest-Omicron recombinant "Kraken" (XBB1.5) (<1%), whereas 16.8% of the samples belonged to other SARS-CoV-2 (sub)lineages. The detected SARS-CoV-2 (sub)lineages resulted in eight COVID-19 pandemic waves in Serbia, which correspond to the pandemic waves reported in Europe and the United States. Wave dynamics in Serbia showed the most resemblance with the profile of pandemic waves in southern Europe, consistent with the southeastern European location of Serbia. The samples were assigned to sixteen SARS-CoV-2 Nextstrain clades: 20A, 20B, 20C, 20D, 20E, 20G, 20I, 21J, 21K, 21L, 22A, 22B, 22C, 22D, 22E, and 22F and six different Omicron recombinants (XZ, XAZ, XAS, XBB, XBF, and XBK). The 10 most common mutations detected in the coding and untranslated regions of the SARS-CoV-2 genomes included four mutations affecting the spike protein (S:D614G, S:T478K, S:P681H, and S:S477N) and one mutation at each of the following positions: 5'-untranslated region (5'UTR:241); N protein (N:RG203KR); NSP3 protein (NSP3:F106F); NSP4 protein (NSP4:T492I); NSP6 protein (NSP6: S106/G107/F108 - triple deletion), and NSP12b protein (NSP12b:P314L). This national-level study is the most comprehensive in terms of sequencing and genomic surveillance of SARS-CoV-2 during the pandemic in Serbia, highlighting the importance of establishing and maintaining good national practice for monitoring SARS-CoV-2 and other viruses circulating worldwide.
Language	English
Publishing date	2024-02-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2024.1332276
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Article: The comparison of SARS-CoV-2 antibody levels in medical personnel induced by different types of vaccines compared to the natural infection.

Božić, Ljiljana / Knežević, Darija / Travar, Maja / Miljuš, Nataša / Petković, Miroslav / Aćimović, Jela / Dević, Jelena Djaković / Stojiljković, Miloš P / Bokonjić, Dejan / Škrbić, Ranko

Central-European journal of immunology

2023 Volume 48, Issue 1, Page(s) 35–42

Abstract: Introduction: During the last two and a half years, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread around the world. Most of the SARS-CoV-2 vaccines are designed to produce anti-SARS-CoV-2 immunoglobulin G (IgG) ... ...

Abstract	Introduction: During the last two and a half years, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread around the world. Most of the SARS-CoV-2 vaccines are designed to produce anti-SARS-CoV-2 immunoglobulin G (IgG) against the viral S-glycoprotein. The aim of this study was to measure the anti-S antibody titres among the medical personnel who had been fully vaccinated with different types of vaccines, and to compare them with those who were COVID-19 convalescents. Material and methods: In this study serum was collected from 261 healthcare workers, of whom 227 were vaccinated, while 34 were recovered participants who were not immunised. Serum samples were collected 21 days after the first dose and 60 and 180 days after the second dose of the vaccines and tested with a commercial ELISA kit. Results: The highest antibody level (12 AU/ml) was measured in the Pfizer-BioNTech group, followed by Sinopharm (9.3 AU/ml), Sputnik V (5.9 AU/ml), Sinovac (4.6 AU/ml) and Oxford/Astra- Zeneca vaccine (2.5 AU/ml) 60 days after the second dose of the vaccines (90 days after the first dose). The seropositivity rate for mRNA vaccine was 88.5%, for vector vaccines 86.2% and for inactivated vaccines 71.4%. When comparing these antibody levels with COVID-19 convalescents, higher antibody titres were found in vaccinated participants (5.76 AU/ml vs 7.06 AU/ml), but the difference was not significant (p = 0.08). Conclusions: Individuals vaccinated with mRNA and vector vaccines had a higher seroconversion rate compared to the group vaccinated with inactivated vaccines, or convalescents.
Language	English
Publishing date	2023-02-23
Publishing country	Poland
Document type	Journal Article
ZDB-ID	1336421-2
ISSN	1644-4124 ; 1426-3912
ISSN (online)	1644-4124
ISSN	1426-3912
DOI	10.5114/ceji.2023.125239
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Article ; Online: Early initiation of renal replacement therapy improves survival in patients with acute kidney injury

Knežević Violeta / Azaševac Tijana / Šibalić-Simin Marija / Sladojević Vesna / Urošević Ivana / Ćelić Dejan

Vojnosanitetski Pregled, Vol 78, Iss 10, Pp 1028-

2021 Volume 1035

Abstract: Background/Aim. Defining renal replacement therapy (RRT) initiation in critically ill patients with acute kidney injury (AKI) has become an imperative for nephrologists and intensivists. The aim of this study was to determine 28-day survival and the ... ...

Abstract	Background/Aim. Defining renal replacement therapy (RRT) initiation in critically ill patients with acute kidney injury (AKI) has become an imperative for nephrologists and intensivists. The aim of this study was to determine 28-day survival and the renal function recovery in patients with AKI. Methods. A single-center retrospective study included 385 surgical and non-surgical patients with AKI and episode of AKI in chronic kidney disease who were admitted to the Emergency Center of Clinical Center of Vojvodina (Novi Sad, Serbia) between 2014 and 2017 and received RRT. Patients with the Kidney Disease Improving Global Outcomes (KDIGO) stage 2 AKI and/or volume overload were assigned to the “early” group with RRT (dialysis) start within 24 h of the diagnosis; patients with poor response to conservative treatment or evidence of clinical complications associated with AKI were assigned to the “late” RRT group. Results. Based on the retrospective analysis we found that 241 patients (62.6%) received “early” RRT within 24 h. Patients in the “early” RRT group had significantly higher survival compared to the “late” RRT group (63.9% vs. 36.1%; p = 0.001). The “early” RRT group had more patients with renal function recovery (56.8%), but without statistical significance (p = 0.514). The patients who started RRT within 24 hours with the Sequential Organ Failure Assessment (SOFA) score of 1–3 were twice likely to recover renal function in relation to the patients with the SOFA score of 4 or higher [odds ratio (OR) = 2.01; 95% confidence interval (CI): 1.37–2.95; p < 0.001], while septic patients had a 62% lower chance of renal function recovery in relation to non-septic patients (OR = 0.38; 95% CI: 0.18–0.82; p = 0.013). In the “late” RRT group, it was found that non-diabetic patients had 3.8 times greater chance for renal function recovery compared to diabetic patients (OR = 3.53; 95% CI: 1.27–9.83; p = 0.016). Conclusions. Patients with the early initiation of RRT had significantly improved 28-day survival.
Keywords	acute kidney injury ; renal dialysis ; mortality ; risk assessment ; survival ; time factors ; Medicine (General) ; R5-920
Subject code	616 ; 610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Military Health Department, Ministry of Defance, Serbia
Document type	Article ; Online
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Article ; Online: The importance of anticoagulation in COVID-19-related acute kidney injury requiring continuous renal replacement therapy

Knežević Violeta / Azaševac Tijana / Stražmešter-Majstorović Gordana / Marković Mira / Ružić Maja / Turkulov Vesna / Gocić Nataša / Milijašević Dragana / Ćelić Dejan

Srpski Arhiv za Celokupno Lekarstvo, Vol 150, Iss 1-2, Pp 29-

2022 Volume 34

Abstract: Introduction/Objective. In Serbia, the coronavirus disease 2019 (COVID-19) pandemic began in early March 2020. The aim of this study is to summarize clinical experience in the treatment of COVID-19-associated acute kidney injury by methods of continuous ... ...

Abstract	Introduction/Objective. In Serbia, the coronavirus disease 2019 (COVID-19) pandemic began in early March 2020. The aim of this study is to summarize clinical experience in the treatment of COVID-19-associated acute kidney injury by methods of continuous renal replacement therapy (CRRT) with the focus on the amount of the administered dose of unfractionated heparin. Methods. The study covers 12 patients treated with CRRT at the Clinic for Infectious Diseases at the Clinical Center of Vojvodina from March 6 to May 20, 2020. Antithrombotic prophylaxis, risk of venous thromboembolism (VTE), applied therapy, biochemical parameters before and after CRRT, anticoagulation and other CRRT parameters were analyzed. Results. The mean age of the patients was 61.54 ± 10.37 years and seven (58.3%) were men. All the patients received standard thromboprophylaxis. Nine (75%) patients had Padua Prediction Score for Risk of VTE ≥ 4, but none developed a thrombotic event. Seven critically ill patients with multi-organic dysfunction developed acute kidney injury dependent on CRRT. The mean CRRT dose was 36.6 ml/kg/h, the mean bolus dose of unfractionated heparin was 3250 ± 1138.18 IU, and the continuous dose was 1112.5 ± 334.48 IU/kg/h. Discontinuation of CRRT due to the clotting circuit was necessary in only one patient. The values of leukocytes, AST, ALT, GGT, aPTT, PT were significantly higher after CRRT compared to urea, creatinine, potassium, chlorine and magnesium, whose values were significantly lower. Conclusion. In our COVID-19 patients who had high inflammatory parameters and D-dimer and an estimated risk of developing deep vein thrombosis, the implementation pre-dilution continuous venovenous hemodiafiltration with antithrombotic membrane and 1/₃ to 1/₂ higher unfractionated heparin doses than the recommended one, the filter life lasted longer with no complications.
Keywords	covid 19 ; continuous renal replacement therapy ; acute kidney injury ; thrombotic events ; Medicine ; R
Subject code	616 ; 610
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Serbian Medical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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