LIVIVO - Search results -

Search results

Result 1 - 10 of total 323

Search options

Article ; Online: Potential of rice tillering for sustainable food production.

Takai, Toshiyuki

2023 Volume 75, Issue 3, Page(s) 708–720

Abstract: Tillering, also known as shoot branching, is a fundamental trait for cereal crops such as rice to produce sufficient panicle numbers. Effective tillering that guarantees successful panicle production is essential for achieving high crop yields. Recent ... ...

Abstract	Tillering, also known as shoot branching, is a fundamental trait for cereal crops such as rice to produce sufficient panicle numbers. Effective tillering that guarantees successful panicle production is essential for achieving high crop yields. Recent advances in molecular biology have revealed the mechanisms underlying rice tillering; however, in rice breeding and cultivation, there remain limited genes or alleles suitable for effective tillering and high yields. A recently identified quantitative trait locus (QTL) called MORE PANICLES 3 (MP3) has been cloned as a single gene and shown to promote tillering and to moderately increase panicle number. This gene is an ortholog of the maize domestication gene TB1, and it has the potential to increase grain yield under ongoing climate change and in nutrient-poor environments. This review reconsiders the potential and importance of tillering for sustainable food production. Thus, I provide an overview of rice tiller development and the currently understood molecular mechanisms that underly it, focusing primarily on the biosynthesis and signaling of strigolactones, effective QTLs, and the importance of MP3 (TB1). The possible future benefits in using promising QTLs such as MP3 to explore agronomic solutions under ongoing climate change and in nutrient-poor environments are also highlighted.
MeSH term(s)	Oryza/genetics ; Plant Breeding ; Quantitative Trait Loci ; Edible Grain/genetics ; Phenotype
Language	English
Publishing date	2023-11-06
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	2976-2
ISSN	1460-2431 ; 0022-0957
ISSN (online)	1460-2431
ISSN	0022-0957
DOI	10.1093/jxb/erad422
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 55/29: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Evaluation of Steroid Pulse Therapy Responsiveness in Myelin-Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis.

Takai, Yasuyuki / Yamagami, Akiko / Iwasa, Mayumi / Inoue, Kenji / Wakakura, Masato / Takahashi, Toshiyuki / Tanaka, Keiko

Cureus

2024 Volume 16, Issue 3, Page(s) e56673

Abstract: Purpose: Myelin-oligodendrocyte glycoprotein antibody-positive optic neuritis (MOGON) is usually responsive to the steroid, but, for some patients, steroid pulse therapy alone may be inadequate. This study aimed to investigate the factors predicting the ...

Abstract	Purpose: Myelin-oligodendrocyte glycoprotein antibody-positive optic neuritis (MOGON) is usually responsive to the steroid, but, for some patients, steroid pulse therapy alone may be inadequate. This study aimed to investigate the factors predicting the response to steroid pulse therapy in MOGON. Methods: This study included 17 patients (24 eyes) with MOGON, who received single steroid pulse therapy as initial treatment. Best corrected visual acuity (BCVA) and mean deviation (MD) values after treatment were examined concerning findings at onset. Results: No correlation was found between BCVA at onset and after treatment, but a correlation was observed between MD values at onset and after treatment (correlation coefficient 0.48, p=0.01, Spearman's rank correlation coefficient). Age, gender, duration from onset to treatment, magnetic resonance imaging findings, and optical coherence tomography findings did not affect visual function after treatment. Conclusions: Severe visual field impairment at onset may indicate that additional treatment may be necessary.
Language	English
Publishing date	2024-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.56673
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: In-frame mutation in rice TEOSINTE BRANCHED1 (OsTB1) improves productivity under phosphorus deficiency.

Ishizaki, Takuma / Ueda, Yoshiaki / Takai, Toshiyuki / Maruyama, Kyonoshin / Tsujimoto, Yasuhiro

Plant science : an international journal of experimental plant biology

2023 Volume 330, Page(s) 111627

Abstract: Tillering is an important trait in rice productivity. We introduced mutations into the coding region of rice TEOSINTE BRANCHED1 (OsTB1), which is a negative regulator of tillering, using CRISPR/Cas9. The frameshift mutants exhibited substantially ... ...

Abstract	Tillering is an important trait in rice productivity. We introduced mutations into the coding region of rice TEOSINTE BRANCHED1 (OsTB1), which is a negative regulator of tillering, using CRISPR/Cas9. The frameshift mutants exhibited substantially enhanced tillering and produced 3.5 times more panicles than the non-mutated plants at maturity. This enhanced tillering resulted in increased spikelet number; however, grain yields did not increase due to substantially reduced filled grain rate and 1,000-grain weight. In contrast, in-frame mutations in OsTB1 had the effect of slightly increasing tiller numbers, and the in-frame mutants had 40% more panicles than non-mutated plants. The grain yield of in-frame mutants also did not increase on nutrient-rich soil; however, under phosphorus-deficient conditions, where tillering is constrained, the in-frame mutants gave a significantly higher grain yield than non-mutated plants due to higher spikelet number and maintained filled grain rate. Rice grassy tiller1 (OsGT1)/OsHox12, which is directly regulated by OsTB1 to suppress tillering, was moderately down-regulated in in-frame mutants, suggesting that OsTB1 with the in-frame mutation shows partial function of intact OsTB1 in regulating OsGT1/OsHox12. We propose that mildly enhanced tillering by in-frame mutation of OsTB1 can improve grain yield under low phosphorus conditions.
MeSH term(s)	Oryza/genetics ; Zea mays ; Phosphorus ; Mutation ; Phenotype ; Plant Proteins/genetics
Chemical Substances	Phosphorus (27YLU75U4W) ; Plant Proteins
Language	English
Publishing date	2023-02-01
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	742010-9
ISSN	1873-2259 ; 0168-9452
ISSN (online)	1873-2259
ISSN	0168-9452
DOI	10.1016/j.plantsci.2023.111627
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 77/717: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Identification of quantitative trait loci for γ‐oryzanol concentration using a cross between cultivars with extremely high and low γ‐oryzanol levels

Nakano, Hiroshi / Takai, Toshiyuki / Kondo, Motohiko

Cereal Chemistry. 2023 , v. 100, no. 3 p.650-662

2023

Abstract: BACKGROUND AND OBJECTIVE: Aside from its various biomedical effects, γ‐oryzanol is a biomarker for heat stress in rice (Oryza sativa L.). Recently, we found that a japonica cultivar Momiroman had the highest γ‐oryzanol among 92 cultivars. In the present ... ...

Abstract	BACKGROUND AND OBJECTIVE: Aside from its various biomedical effects, γ‐oryzanol is a biomarker for heat stress in rice (Oryza sativa L.). Recently, we found that a japonica cultivar Momiroman had the highest γ‐oryzanol among 92 cultivars. In the present study, we aimed to detect the quantitative trait locus (QTLs) for the concentrations of cycloartenyl ferulate (1), 24‐methylenecycloartanyl ferulate (2), and total γ‐oryzanol in the populations from a cross between Momiroman and an indica cultivar Takanari. FINDINGS: We detected the QTLs for the concentrations of 1, 2, and/or total γ‐oryzanol on chromosomes 4, 5, 9, and 11. The Momiroman alleles at the QTLs on chromosomes 4, 5, and 11 increased the concentrations of 1, 2, and/or total γ‐oryzanol, whereas the Takanari alleles at the QTLs on chromosome 9 increased. CONCLUSION: Considering the literature data, the japonica alleles at the QTLs on chromosomes 4, 5, and 11 may increase the concentrations of 1, 2, and/or total γ‐oryzanol in the indica genetic background. SIGNIFICANCE AND NOVELTY: This study revealed the QTLs for the concentrations of 1, 2, and/or total γ‐oryzanol on chromosomes 4, 5, 9, and 11, providing essential information for the development of cultivars with specific biomedical properties or heat stress resistance.
Keywords	Oryza sativa ; biomarkers ; chemistry ; chromosomes ; cultivars ; genetic background ; heat stress ; quantitative trait loci ; quantitative traits ; rice ; stress tolerance
Language	English
Dates of publication	2023-05
Size	p. 650-662.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	242360-1
ISSN	0009-0352
ISSN	0009-0352
DOI	10.1002/cche.10639
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 937: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: LILRB4/gp49B Co-Localizes with Integrin via Fibronectin at Focal Adhesion Sites on Mast Cells.

Miyamoto, Shotaro / Chiba, Takumi / Itoi, So / Su, Mei-Tzu / Takai, Toshiyuki

The Tohoku journal of experimental medicine

2023 Volume 259, Issue 4, Page(s) 273–284

Abstract: Mast cells protect a host from invasion by infectious agents and environmental allergens through activation of innate and adaptive immune receptors, their excessive activation being tightly regulated by inhibitory receptors, such as leukocyte ... ...

Abstract	Mast cells protect a host from invasion by infectious agents and environmental allergens through activation of innate and adaptive immune receptors, their excessive activation being tightly regulated by inhibitory receptors, such as leukocyte immunoglobulin-like receptor (LILR)B4 (gp49B in mice). However, the regulatory mechanism of LILRB4/gp49B expressed on mast cells remains to be clarified in relation to their recently identified ligand, fibronectin (FN), a direct activator of integrins and an indirect stimulator of high-affinity Fc receptor for IgE (FcεRI). Confocal microscopic analysis suggested that gp49B is spatially close to integrin β
MeSH term(s)	Animals ; Mice ; Fibronectins ; Focal Adhesions ; Integrins ; Mast Cells/physiology ; Receptors, IgE
Chemical Substances	Fibronectins ; Integrins ; Receptors, IgE ; Lilrb4 protein, mouse
Language	English
Publishing date	2023-01-13
Publishing country	Japan
Document type	Journal Article
ZDB-ID	123477-8
ISSN	1349-3329 ; 0040-8727
ISSN (online)	1349-3329
ISSN	0040-8727
DOI	10.1620/tjem.2023.J001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.155: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Clinical Features and Prognostic Factors in Anti-Myelin Oligodendrocyte Glycoprotein Antibody Positive Optic Neuritis.

Takai, Yasuyuki / Yamagami, Akiko / Iwasa, Mayumi / Inoue, Kenji / Wakakura, Masato / Takahashi, Toshiyuki / Tanaka, Keiko

Neuro-ophthalmology (Aeolus Press)

2023 Volume 48, Issue 2, Page(s) 134–141

Abstract: In order to review the clinical features of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis (MOGON), we investigated the clinical characteristics, visual function, optical coherence tomography findings, and magnetic resonance ... ...

Abstract	In order to review the clinical features of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis (MOGON), we investigated the clinical characteristics, visual function, optical coherence tomography findings, and magnetic resonance imaging of 31 patients (44 eyes). MOGON was more common in middle age without sex difference and was characterised by pain on eye movement and optic disc swelling. Magnetic resonance imaging lesions tended to be long with inflammation around the optic nerve sheath; longer lesions were associated with worse visual acuities at onset. Recurrence was significantly associated with retinal nerve fibre layer thinning, and thus, it is important to reduce recurrence as much as possible.
Language	English
Publishing date	2023-12-04
Publishing country	England
Document type	Journal Article
ZDB-ID	604820-1
ISSN	1744-506X ; 0165-8107
ISSN (online)	1744-506X
ISSN	0165-8107
DOI	10.1080/01658107.2023.2287518
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1784: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Fibronectin on target cells attenuates natural cytotoxicity of NK cells via myeloid immune checkpoint ILT3/LILRB4/gp49B.

Itagaki, Fumika / Nakatsuka, Keita / Sakai, Haruka / Endo, Shota / Su, Mei-Tzu / Takai, Toshiyuki

International immunology

2023 Volume 35, Issue 7, Page(s) 339–348

Abstract: Natural killer (NK) cells play pivotal roles in innate immunity as well as in anti-tumor responses via natural killing, while their activity is tightly regulated by cell-surface inhibitory receptors. Immunoglobulin-like transcript 3/leukocyte ... ...

Abstract	Natural killer (NK) cells play pivotal roles in innate immunity as well as in anti-tumor responses via natural killing, while their activity is tightly regulated by cell-surface inhibitory receptors. Immunoglobulin-like transcript 3/leukocyte immunoglobulin-like receptor B4 (ILT3/LILRB4, also known as gp49B in mice) is an inhibitory receptor expressed on activated NK cells as well as myeloid-lineage cells. The common physiologic ligand of human LILRB4 and gp49B was identified very recently as fibronectin, particularly the N-terminal 30 kDa domain (FN30). We hypothesized that LILRB4 could bind fibronectin on target cells in trans together with integrins, classical fibronectin receptors, in cis and deliver an inhibitory signal in NK cells, leading to attenuated natural killing. Flow cytometric and confocal microscopic analyses of NK cell-surface gp49B and integrins suggested that these novel and classical fibronectin receptors, respectively, co-engage fibronectin immobilized on a culture plate. Biochemical analyses indicated that tyrosine phosphorylation of spleen tyrosine kinase was augmented in gp49B-deficient NK cells upon binding to the immobilized fibronectin. While surface fibronectin-poor YAC-1 cells were evenly sensitive as to natural killing of both gp49B-positive and -negative NK cells, the killing of fibronectin-rich Lewis lung carcinoma cells, but not the FN30-knockout cells, was augmented among gp49B-deficient NK cells. These results suggest that the natural cytotoxicity of NK cells is negatively regulated through LILRB4/gp49B sensing fibronectin on target cells, which sheds light on the unexpected role of LILRB4 and fibronectin as a potential attenuator of NK cell cytotoxicity in the tumor microenvironment.
MeSH term(s)	Mice ; Animals ; Humans ; Fibronectins/metabolism ; Killer Cells, Natural ; Integrins/metabolism ; Receptors, Fibronectin/metabolism ; Immunoglobulins/metabolism ; Membrane Glycoproteins/metabolism ; Receptors, Immunologic/metabolism
Chemical Substances	Fibronectins ; Integrins ; Receptors, Fibronectin ; Immunoglobulins ; LILRB4 protein, human ; Membrane Glycoproteins ; Receptors, Immunologic
Language	English
Publishing date	2023-06-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1013745-2
ISSN	1460-2377 ; 0953-8178
ISSN (online)	1460-2377
ISSN	0953-8178
DOI	10.1093/intimm/dxad012
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2619: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 70: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Identification of Quantitative Trait Loci for the Concentrations of Phenylpropanoid Glycosides in Brown Rice.

Nakano, Hiroshi / Takai, Toshiyuki / Kondo, Motohiko

ACS omega

2019 Volume 4, Issue 17, Page(s) 17317–17325

Abstract: Rice ( ...

Abstract	Rice (
Language	English
Publishing date	2019-10-07
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.9b02030
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: In-frame mutation in rice TEOSINTE BRANCHED1 (OsTB1) improves productivity under phosphorus deficiency

Ishizaki, Takuma / Ueda, Yoshiaki / Takai, Toshiyuki / Maruyama, Kyonoshin / Tsujimoto, Yasuhiro

Plant Science. 20232023 May 01, Feb. 01, v. 330 p.111627-

2023

Abstract	Tillering is an important trait in rice productivity. We introduced mutations into the coding region of rice TEOSINTE BRANCHED1 (OsTB1), which is a negative regulator of tillering, using CRISPR/Cas9. The frameshift mutants exhibited substantially enhanced tillering and produced 3.5 times more panicles than the non-mutated plants at maturity. This enhanced tillering resulted in increased spikelet number; however, grain yields did not increase due to substantially reduced filled grain rate and 1,000-grain weight. In contrast, in-frame mutations in OsTB1 had the effect of slightly increasing tiller numbers, and the in-frame mutants had 40% more panicles than non-mutated plants. The grain yield of in-frame mutants also did not increase on nutrient-rich soil; however, under phosphorus-deficient conditions, where tillering is constrained, the in-frame mutants gave a significantly higher grain yield than non-mutated plants due to higher spikelet number and maintained filled grain rate. Rice grassy tiller1 (OsGT1)/OsHox12, which is directly regulated by OsTB1 to suppress tillering, was moderately down-regulated in in-frame mutants, suggesting that OsTB1 with the in-frame mutation shows partial function of intact OsTB1 in regulating OsGT1/OsHox12. We propose that mildly enhanced tillering by in-frame mutation of OsTB1 can improve grain yield under low phosphorus conditions.
Keywords	CRISPR-Cas systems ; grain yield ; mutation ; phosphorus ; rice ; soil ; spikelets ; tillering ; D14 ; DAT ; HPT ; OsGT1 ; OsTB1 ; PCR ; qRT-PCR ; QTLs ; TB1 ; WT ; SD medium ; Y2H ; CRISPR/Cas9 ; In-frame mutation ; Phosphorus deficiency ; TEOSINTE BRANCHED1
Language	English
Dates of publication	2023-0201
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	742010-9
ISSN	1873-2259 ; 0168-9452
ISSN (online)	1873-2259
ISSN	0168-9452
DOI	10.1016/j.plantsci.2023.111627
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 77/717: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs.

Su, Mei-Tzu / Kumata, Sakiko / Endo, Shota / Okada, Yoshinori / Takai, Toshiyuki

Oncoimmunology

2022 Volume 11, Issue 1, Page(s) 2060907

Abstract: Myeloid-derived suppressor cells (MDSCs) are a population of immune suppressive cells that are involved in tumor-associated immunosuppression, and dominate tumor progression and metastasis. In this study, we report that the leukocyte immunoglobulin-like ... ...

Abstract	Myeloid-derived suppressor cells (MDSCs) are a population of immune suppressive cells that are involved in tumor-associated immunosuppression, and dominate tumor progression and metastasis. In this study, we report that the leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4, murine ortholog gp49B) orchestrates the polarization of MDSCs to exhibit pro-tumor phenotypes. We found that gp49B deficiency inhibited tumor metastases of cancer cells, and reduced tumor-infiltration of monocytic MDSCs (M-MDSCs) in tumor-bearing mice. Gp49B
MeSH term(s)	Animals ; Immunoglobulins/metabolism ; Membrane Glycoproteins/genetics ; Mice ; MicroRNAs/genetics ; Myeloid-Derived Suppressor Cells/metabolism ; Neoplasm Metastasis ; Neoplasms/pathology ; Receptors, Immunologic/genetics ; Tumor Microenvironment ; Vascular Endothelial Growth Factor A/metabolism
Chemical Substances	Immunoglobulins ; Lilrb4 protein, mouse ; Membrane Glycoproteins ; MicroRNAs ; Receptors, Immunologic ; Vascular Endothelial Growth Factor A
Language	English
Publishing date	2022-04-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2645309-5
ISSN	2162-402X ; 2162-4011
ISSN (online)	2162-402X
ISSN	2162-4011
DOI	10.1080/2162402X.2022.2060907
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito