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Article ; Online: A method for prioritizing the modification of ergonomic and physical aspects of the workplace to enhance overall worker satisfaction in control centre buildings.

Hashemi, Fatemeh / Eghbali, Seyed Rahman / Mallory-Hill, Shauna / Hamedi, Mohsen

International journal of occupational safety and ergonomics : JOSE

2021 Volume 27, Issue 2, Page(s) 323–335

Abstract: This article aims to develop a method for prioritizing indoor environmental quality parameters in the workplace (i.e., temperature, lighting, acoustics, air quality, layout, furnishing, cleanliness and maintenance) to enhance occupants' workspace ... ...

Abstract	This article aims to develop a method for prioritizing indoor environmental quality parameters in the workplace (i.e., temperature, lighting, acoustics, air quality, layout, furnishing, cleanliness and maintenance) to enhance occupants' workspace satisfaction. Data were collected using a web-based survey of 12 Iranian control centre buildings (CCBs) of combined cycle power plants. The results showed that fewer than half of occupants are satisfied with their workplace. Corrective measures would cost the owners an exorbitant amount of money if they were to try to address all of the parameters. Therefore, a statistical analysis framework was applied to determine each parameter's importance in relation to overall workspace satisfaction. Based on detailed analysis, two levels of importance have been defined for ergonomic modification of each CCB. The statistical approach developed in this study can be applied to all kinds of buildings to determine where ergonomic modification is most likely to produce higher workspace satisfaction.
MeSH term(s)	Air Pollution, Indoor/analysis ; Ergonomics ; Humans ; Iran ; Personal Satisfaction ; Workplace
Language	English
Publishing date	2021-04-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1335568-5
ISSN	2376-9130 ; 1080-3548
ISSN (online)	2376-9130
ISSN	1080-3548
DOI	10.1080/10803548.2021.1872334
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Article ; Online: Answering the Call: The Response of Centers for Disease Control and Prevention's Federal Public Health Nursing Workforce to the COVID-19 Pandemic.

Zauche, Lauren Head / Pomeroy, Mary / Demeke, Hanna B / Mettee Zarecki, Shauna L / Williams, Jennifer L / Newsome, Kimberly / Hill, Laura / Dooyema, Carrie A

American journal of public health

2022 Volume 112, Issue S3, Page(s) S226–S230

MeSH term(s)	COVID-19 ; Centers for Disease Control and Prevention, U.S. ; Humans ; Pandemics/prevention & control ; Public Health ; Public Health Nursing ; United States/epidemiology ; Workforce
Language	English
Publishing date	2022-06-09
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	121100-6
ISSN	1541-0048 ; 0090-0036 ; 0002-9572
ISSN (online)	1541-0048
ISSN	0090-0036 ; 0002-9572
DOI	10.2105/AJPH.2021.306703
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Article: Role of Signaling Molecules in Mitochondrial Stress Response.

Hill, Shauna / Sataranatarajan, Kavithalakshmi / Van Remmen, Holly

Frontiers in genetics

2018 Volume 9, Page(s) 225

Abstract: Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria regulate redox homeostasis, maintain energy (ATP) production through oxidative phosphorylation, buffer calcium levels, and control cell death through ... ...

Abstract	Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria regulate redox homeostasis, maintain energy (ATP) production through oxidative phosphorylation, buffer calcium levels, and control cell death through apoptosis. In addition to these critical cell functions, recent evidence supports a signaling role for mitochondria. For example, studies over the past few years have established that peptides released from the mitochondria mediate stress responses such as the mitochondrial unfolded protein response (UPR
Language	English
Publishing date	2018-07-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2018.00225
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Article: First Detection of Paralytic Shellfish Toxins from

Barua, Abanti / Ajani, Penelope A / Ruvindy, Rendy / Farrell, Hazel / Zammit, Anthony / Brett, Steve / Hill, David / Sarowar, Chowdhury / Hoppenrath, Mona / Murray, Shauna A

Microorganisms

2020 Volume 8, Issue 6

Abstract: In 2016, 2017 and 2018, elevated levels of the ... ...

Abstract	In 2016, 2017 and 2018, elevated levels of the species
Language	English
Publishing date	2020-06-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms8060905
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Article ; Online: Mitochondrial stress signaling in longevity

Shauna Hill / Holly Van Remmen

Redox Biology, Vol 2, Iss C, Pp 936-

A new role for mitochondrial function in aging

2014 Volume 944

Abstract: Mitochondria are principal regulators of cellular function and metabolism through production of ATP for energy homeostasis, maintenance of calcium homeostasis, regulation of apoptosis and fatty acid oxidation to provide acetyl CoA for fueling the ... ...

Abstract	Mitochondria are principal regulators of cellular function and metabolism through production of ATP for energy homeostasis, maintenance of calcium homeostasis, regulation of apoptosis and fatty acid oxidation to provide acetyl CoA for fueling the electron transport chain. In addition, mitochondria play a key role in cell signaling through production of reactive oxygen species that modulate redox signaling. Recent findings support an additional mechanism for control of cellular and tissue function by mitochondria through complex mitochondrial–nuclear communication mechanisms and potentially through extracellular release of mitochondrial components that can act as signaling molecules. The activation of stress responses including mitophagy, mitochondrial number, fission and fusion events, and the mitochondrial unfolded protein response (UPRMT) requires mitochondrial–nuclear communication for the transcriptional activation of nuclear genes involved in mitochondrial quality control and metabolism. The induction of these signaling pathways is a shared feature in long-lived organisms spanning from yeast to mice. As a result, the role of mitochondrial stress signaling in longevity has been expansively studied. Current and exciting studies provide evidence that mitochondria can also signal among tissues to up-regulate cytoprotective activities to promote healthy aging. Alternatively, mitochondria release signals to modulate innate immunity and systemic inflammatory responses and could consequently promote inflammation during aging. In this review, established and emerging models of mitochondrial stress response pathways and their potential role in modulating longevity are discussed.
Keywords	Mitochondria ; Longevity ; Retrograde response ; Mitochondrial unfolded protein response ; Mitochondrial signaling ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
Subject code	570
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Mitochondrial stress signaling in longevity: a new role for mitochondrial function in aging.

Hill, Shauna / Van Remmen, Holly

Redox biology

2014 Volume 2, Page(s) 936–944

Abstract	Mitochondria are principal regulators of cellular function and metabolism through production of ATP for energy homeostasis, maintenance of calcium homeostasis, regulation of apoptosis and fatty acid oxidation to provide acetyl CoA for fueling the electron transport chain. In addition, mitochondria play a key role in cell signaling through production of reactive oxygen species that modulate redox signaling. Recent findings support an additional mechanism for control of cellular and tissue function by mitochondria through complex mitochondrial-nuclear communication mechanisms and potentially through extracellular release of mitochondrial components that can act as signaling molecules. The activation of stress responses including mitophagy, mitochondrial number, fission and fusion events, and the mitochondrial unfolded protein response (UPR(MT)) requires mitochondrial-nuclear communication for the transcriptional activation of nuclear genes involved in mitochondrial quality control and metabolism. The induction of these signaling pathways is a shared feature in long-lived organisms spanning from yeast to mice. As a result, the role of mitochondrial stress signaling in longevity has been expansively studied. Current and exciting studies provide evidence that mitochondria can also signal among tissues to up-regulate cytoprotective activities to promote healthy aging. Alternatively, mitochondria release signals to modulate innate immunity and systemic inflammatory responses and could consequently promote inflammation during aging. In this review, established and emerging models of mitochondrial stress response pathways and their potential role in modulating longevity are discussed.
MeSH term(s)	Aging/metabolism ; Animals ; Humans ; Longevity ; Mitochondria/metabolism ; Oxidative Stress ; Signal Transduction
Language	English
Publishing date	2014-07-27
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2701011-9
ISSN	2213-2317
ISSN	2213-2317
DOI	10.1016/j.redox.2014.07.005
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Article ; Online: Mitigation of SARS-CoV-2 by Using Transition Metal Nanozeolites and Quaternary Ammonium Compounds as Antiviral Agents in Suspensions and Soft Fabric Materials.

Guerrero-Arguero, Israel / Khan, Siddiqur Rahman / Henry, Brandon M / Garcia-Vilanova, Andreu / Chiem, Kevin / Ye, Chengjin / Shrestha, Sweta / Knight, Deborah / Cristner, Mark / Hill, Shauna / Waldman, W James / Dutta, Prabir K / Torrelles, Jordi B / Martinez-Sobrido, Luis / Nagy, Amber M

International journal of nanomedicine

2023 Volume 18, Page(s) 2307–2324

Abstract: Introduction: The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the need for novel, affordable, and efficient reagents to help reduce viral transmission, especially in high-risk environments including medical treatment facilities, close ... ...

Abstract	Introduction: The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the need for novel, affordable, and efficient reagents to help reduce viral transmission, especially in high-risk environments including medical treatment facilities, close quarters, and austere settings. We examined transition-metal nanozeolite suspensions and quaternary ammonium compounds as an antiviral surface coating for various textile materials. Methods: Zeolites are crystalline porous aluminosilicate materials, with the ability of ion-exchanging different cations. Nanozeolites (30 nm) were synthesized and then ion-exchanged with silver, zinc and copper ions. Benzalkonium nitrate (BZN) was examined as the quaternary ammonium ion (quat). Suspensions of these materials were tested for antiviral activity towards SARS-CoV-2 using plaque assay and immunostaining. Suspensions of the nanozeolite and quat were deposited on polyester and cotton fabrics and the ability of these textiles towards neutralizing SARS-CoV-2 was examined. Results: We hypothesized that transition metal ion containing zeolites, particularly silver and zinc (AM30) and silver and copper (AV30), would be effective in reducing the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Additionally, AM30 and AV30 antiviral potency was tested when combined with a quaternary ammonium carrier, BZN. Our results indicate that exposure of SARS-CoV-2 to AM30 and/or AV30 suspensions reduced viral loads with time and exhibited dose-dependence. Antiviral activities of the combination of zeolite and BZN compositions were significantly enhanced. When used in textiles, AM30 and AV30-coated cotton and polyester fabrics alone or in combination with BZN exhibited significant antiviral properties, which were maintained even after various stress tests, including washes, SARS-CoV-2-repeated exposures, or treatments with soil-like materials. Conclusion: This study shows the efficacy of transition metal nanozeolite formulations as novel antiviral agents and establishes that nanozeolite with silver and zinc ions (AM30) and nanozeolite with silver and copper ions (AV30) when combined with benzalkonium nitrate (BZN) quickly and continuously inactivate SARS-CoV-2 in suspension and on fabric materials.
MeSH term(s)	Humans ; SARS-CoV-2 ; COVID-19/prevention & control ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Silver/chemistry ; Copper ; Quaternary Ammonium Compounds ; Benzalkonium Compounds ; Suspensions ; Zeolites ; Nitrates ; Textiles ; Zinc ; Polyesters
Chemical Substances	Antiviral Agents ; Silver (3M4G523W1G) ; Copper (789U1901C5) ; Quaternary Ammonium Compounds ; Benzalkonium Compounds ; Suspensions ; Zeolites (1318-02-1) ; Nitrates ; Zinc (J41CSQ7QDS) ; Polyesters
Language	English
Publishing date	2023-05-03
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2364941-0
ISSN	1178-2013 ; 1176-9114
ISSN (online)	1178-2013
ISSN	1176-9114
DOI	10.2147/IJN.S396669
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Article ; Online: Can my mechanic fix blue cars? A discussion of health clinicians' interactions with Aboriginal Australian clients.

Hill, Shauna / Ewen, Shaun C / Paul, David / Wilkin, Alice

The Australian journal of rural health

2016 Volume 25, Issue 3, Page(s) 189–192

MeSH term(s)	Attitude of Health Personnel ; Australia ; Cultural Competency ; Health Services, Indigenous/organization & administration ; Humans ; Oceanic Ancestry Group ; Physician-Patient Relations ; Rural Health Services/organization & administration
Language	English
Publishing date	2016-09-16
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2069573-1
ISSN	1440-1584 ; 1038-5282
ISSN (online)	1440-1584
ISSN	1038-5282
DOI	10.1111/ajr.12299
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Article: Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice.

Pharaoh, Gavin / Sataranatarajan, Kavithalakshmi / Street, Kaitlyn / Hill, Shauna / Gregston, Jake / Ahn, Bumsoo / Kinter, Caroline / Kinter, Michael / Van Remmen, Holly

Frontiers in neuroscience

2019 Volume 13, Page(s) 487

Abstract: Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of ... ...

Abstract	Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabolism as an ALS therapeutic target. The goal of this study is to measure changes in metabolic pathways as a function of disease progression in spinal cords of the SOD1
Language	English
Publishing date	2019-05-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2019.00487
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Article ; Online: "I can't remember the last time I was comfortable about being home": lived experience perspectives on thriving following homelessness.

International journal of qualitative studies on health and well-being

2023 Volume 18, Issue 1, Page(s) 2176979

Abstract: Purpose: Strategies for preventing and ending homelessness are frequently measured by their effectiveness on indices of tenancy sustainment. To shift this narrative, we conducted research to identify what is needed to "thrive" following homelessness ... ...

Abstract	Purpose: Strategies for preventing and ending homelessness are frequently measured by their effectiveness on indices of tenancy sustainment. To shift this narrative, we conducted research to identify what is needed to "thrive" following homelessness from the perspectives of persons with lived experience in Ontario, Canada. Methods: Conducted in the context of a community-based participatory research study aimed at informing the development of intervention strategies, we interviewed 46 persons living with mental illness and/or substance use disorder [ Results: Participants described experiences of "living in a state of lack" following homelessness. This essence was expressed through four themes: 1) housing as part one of the journey to home; 2) finding and keeping "my people"; 3) meaningful activity as critical for thriving following homelessness; and 4) struggling to access mental health supports in the context of challenging circumstances. Conclusions: Individuals struggle to thrive following homelessness in the context of insufficient resources. There is a need to build on existing interventions to address outcomes beyond tenancy sustainment.
MeSH term(s)	Humans ; Ill-Housed Persons ; Housing ; Substance-Related Disorders ; Ontario ; Mental Health
Language	English
Publishing date	2023-01-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2232726-5
ISSN	1748-2631 ; 1748-2623
ISSN (online)	1748-2631
ISSN	1748-2623
DOI	10.1080/17482631.2023.2176979
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