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  1. Book: Drug hypersensitivity

    Pichler, Werner J.

    (Medical clinics of North America ; 94,4)

    2010  

    Author's details guest ed. Werner J. Pichler
    Series title Medical clinics of North America ; 94,4
    Collection
    Language English
    Size XIV S., S. 645 - 879 : Ill., graph. Darst.
    Publisher Saunders an imprint of Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016456651
    ISBN 978-1-4377-2464-6 ; 1-4377-2464-7
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Drug hypersensitivity

    Pichler, Werner J.

    (Immunology and allergy clinics of North America ; 29,3)

    2009  

    Author's details guest ed. Werner J. Pichler
    Series title Immunology and allergy clinics of North America ; 29,3
    Collection
    Language English
    Size XVI S., S. 406 - 620 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016025669
    ISBN 1-4377-1229-0 ; 978-1-4377-1229-2
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Drug hypersensitivity

    Pichler, Werner J.

    78 tables

    2007  

    Author's details ed. W. J. Pichler
    Keywords Drug Hypersensitivity ; Arzneimittelallergie
    Language English
    Size IX, 438 S. : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT015185520
    ISBN 978-3-8055-8269-8 ; 3-8055-8269-2
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Leserbriefe. Eine Penicillinanamnese ist nicht genug!

    Pichler, W. J. / Hausmann, O.

    Swiss medical forum

    2022  Volume 22, Issue 29/30, Page(s) 495

    Language German
    Document type Article
    ZDB-ID 2220114-2
    ISSN 1661-6138
    Database Current Contents Medicine

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  5. Article: Allergen meiden oder sich daran gewöhnen: Das ist die Frage! Da Allergien potentiell vermeidbar sind, steht eine exakte Diagnose der Ursachen im Zentrum der Abklärung. Hier hat es in den letzten 20 Jahren entscheidende Fortschritte gegeben

    Pichler, W. J. / Hausmann, O.

    Swiss medical forum

    2022  Volume 22, Issue 9/10, Page(s) 148

    Language German
    Document type Article
    ZDB-ID 2220114-2
    ISSN 1661-6138
    Database Current Contents Medicine

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  6. Article ; Online: The molecular basis and downstream immune consequences of mycobacteria-host cell interactions.

    Daher, Wassim / Pichler, Virginia / Karam, Jona / Neyrolles, Olivier / Kremer, Laurent

    FEMS microbiology reviews

    2023  Volume 47, Issue 2

    Abstract: Pathogenic mycobacteria gain entry to their hosts by inhalation or ingestion where they adhere to different cell types and are subsequently internalized by professional phagocytic cells, such as macrophages or dendritic cells. Multiple pathogen- ... ...

    Abstract Pathogenic mycobacteria gain entry to their hosts by inhalation or ingestion where they adhere to different cell types and are subsequently internalized by professional phagocytic cells, such as macrophages or dendritic cells. Multiple pathogen-associated molecular patterns present on the mycobacterial surface are recognized by and interact with a diverse panel of phagocytic pattern recognition receptors, representing the first step of the infection process. This review summarizes the current knowledge on the numerous host cell receptors and their associated mycobacterial ligands or adhesins. It further discusses the downstream molecular and cellular events resulting from the engagement of the various receptor-mediated pathways, leading to either intracellular survival of mycobacteria or to activation of host immune defenses. The content presented herein on adhesins and host receptors may serve as a resource for those developing novel therapeutic approaches, e.g. in the design of antiadhesin molecules to prevent bacterial attachment and infection. The collection of mycobacterial surface molecules highlighted in this review may also provide potential new therapeutic targets, diagnostic markers, or vaccine candidates to combat these notoriously challenging and persistent pathogens.
    MeSH term(s) Mycobacterium ; Macrophages/microbiology ; Cell Communication ; Host-Pathogen Interactions
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 283740-7
    ISSN 1574-6976 ; 0168-6445
    ISSN (online) 1574-6976
    ISSN 0168-6445
    DOI 10.1093/femsre/fuad009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Lesebrief. Iatrogene Hypersensitivitätsreaktion

    Pichler, W. J.

    Swiss medical forum

    2016  Volume 16, Issue 48, Page(s) 1054

    Language German
    Document type Article
    ZDB-ID 2220114-2
    ISSN 1424-3784
    Database Current Contents Medicine

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  8. Article: Measurements of thermophysical properties of solid and liquid NIST SRM 316L stainless steel.

    Pichler, Peter / Simonds, Brian J / Sowards, Jeffrey W / Pottlacher, Gernot

    Journal of materials science

    2020  Volume 55

    Abstract: In this work, we perform high accuracy measurements of thermophysical properties for the National Institute of Standards and Technology standard reference material for 316L stainless steel. As these properties can be sensitive to small changes in ... ...

    Abstract In this work, we perform high accuracy measurements of thermophysical properties for the National Institute of Standards and Technology standard reference material for 316L stainless steel. As these properties can be sensitive to small changes in elemental composition even within the allowed tolerances for an alloy class, by selecting a publicly available standard reference material for study our results are particularly useful for the validation of multiphysics models of industrial metal processes. An ohmic pulse-heating system was used to directly measure the electrical resistivity, enthalpy, density, and thermal expansion as functions of temperature. This apparatus applies high current pulses to heat wire-shaped samples from room temperature to metal vaporization. The great advantage of this particular pulse-heating apparatus is the very short experimental duration of 50 μs, which is faster than the collapse of the liquid wire due to gravitational forces, as well as that it prevents any chemical reactions of the hot liquid metal with its surroundings. Additionally, a differential scanning calorimeter was used to measure specific heat capacity from room temperature to around 1400 K. All data are accompanied by uncertainties according to the guide to the expression of uncertainty in measurement.
    Language English
    Publishing date 2020-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-019-04261-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Noninvasive Detection of Smooth Muscle Cell-Derived Hot Spots to Study Atherosclerosis by PET/MRI in Mice.

    Feil, Susanne / Stowbur, Dimitri / Schörg, Barbara F / Ehrlichmann, Walter / Reischl, Gerald / Kneilling, Manfred / Pichler, Bernd J / Feil, Robert

    Circulation research

    2023  Volume 132, Issue 6, Page(s) 747–750

    MeSH term(s) Animals ; Mice ; Positron-Emission Tomography ; Atherosclerosis/diagnostic imaging ; Magnetic Resonance Imaging ; Fluorodeoxyglucose F18
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Research Support, Non-U.S. Gov't ; Journal Article
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.122.322296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Athletes are not at greater risk for death by suicide: A review.

    Pichler, Eva-Maria / Ewers, Simon / Ajdacic-Gross, Vladeta / Deutschmann, Markus / Exner, Jan / Kawohl, Wolfram / Seifritz, Erich / Claussen, Malte Christian

    Scandinavian journal of medicine & science in sports

    2023  Volume 33, Issue 5, Page(s) 569–585

    Abstract: Introduction: Suicide represents a major mental and public health issue. Elite athletes share certain individual and environmental characteristics that may increase their risk for mental illnesses, ultimately leading to suicide. This notion conflicts ... ...

    Abstract Introduction: Suicide represents a major mental and public health issue. Elite athletes share certain individual and environmental characteristics that may increase their risk for mental illnesses, ultimately leading to suicide. This notion conflicts with the general perception of athletes, being the healthiest representatives of society.
    Methods: A comprehensive literature search was carried out through PubMed and Embase databases for relevant publications.
    Results: Recent calls for investigating suicidality among athletes resulted in a considerable amount of literature providing some evidence regarding lower rates of suicide among professional and high-performance athletes as well as similar incidence and prevalence of mental conditions, which are known as risk factors for suicide. Nevertheless, special attention is required in this population as predisposing and precipitating factors might differ from classical features of suicidality in the general population. Sports physicians, sports psychiatrists, and other mental health professionals in elite sports should be aware of early signs of affective disorders, risk of recreational drug abuse, misuse of performance-enhancing medications, sport-specific environmental stressors, serious physical injuries, and presence of physical or mental illness, all of which may increase suicidality. Traumatic brain injury (TBI) is with suicide with higher severity correlated with increased risk. Compared to active athletes, former athletes may have higher rates of suicide due to common life stressors occurring after sports retirement.
    Conclusions: The findings suggest a multidisciplinary approach to suicidality in elite athletes, the main goal of which should be the reduction of suicide-related morbidity and mortality. Further research is required to clarify the existing gaps in the current knowledge of the issue. While having lower rates of suicide, athletes share some similar (affective disorders, drug abuse, mental and physical illness) and unique factors (misuse of performance-enhancing substances, sports-related stressors, sports injuries, TBI) putting them at risk of suicide during active career and retirement.
    MeSH term(s) Humans ; Suicide ; Athletes/psychology ; Mental Disorders ; Sports ; Suicidal Ideation ; Risk Factors
    Language English
    Publishing date 2023-01-30
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1077418-x
    ISSN 1600-0838 ; 0905-7188
    ISSN (online) 1600-0838
    ISSN 0905-7188
    DOI 10.1111/sms.14316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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