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  1. Article ; Online: The Pandemic That Never Left.

    Minhas, Abdul Mannan Khan / Fudim, Marat / Abramov, Dmitry

    Journal of cardiac failure

    2024  

    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2024.02.019
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    Zs.A 4340: Show issues Location:
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  2. Article ; Online: Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction.

    Friedman, Daniel J / Fudim, Marat

    JAMA

    2023  Volume 329, Issue 23, Page(s) 2094–2095

    MeSH term(s) Humans ; Atrial Fibrillation/therapy ; Heart Atria ; Heart Failure/physiopathology ; Heart Failure/therapy ; Stroke Volume ; Heart Rate ; Cardiac Pacing, Artificial/methods
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.7934
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  3. Article ; Online: Emerging devices for heart failure management.

    Chouairi, Fouad / Levin, Allison / Biegus, Jan / Fudim, Marat

    Progress in cardiovascular diseases

    2024  Volume 82, Page(s) 125–134

    Abstract: There have been significant advances in the treatment of heart failure (HF) in recent years, driven by significant strides in guideline-directed medical therapy (GDMT). Despite this, HF is still associated with high levels of morbidity and mortality, and ...

    Abstract There have been significant advances in the treatment of heart failure (HF) in recent years, driven by significant strides in guideline-directed medical therapy (GDMT). Despite this, HF is still associated with high levels of morbidity and mortality, and most patients do not receive optimal medical therapy. In conjunction with the improvement of GDMT, novel device therapies have been developed to better treat HF. These devices include technology capable of remotely monitoring HF physiology, devices that modulate the autonomic nervous system, and those that structurally change the heart with the ultimate aim of addressing the root causes of HF physiology As these device therapies gradually integrate into the fabric of HF patient care, it becomes increasingly important for modern cardiologists to become familiar with them. Hence, the objective of this review is to shed light on currently emerging devices for the treatment of HF.
    MeSH term(s) Humans ; Heart Failure/diagnosis ; Heart Failure/therapy ; Stroke Volume/physiology
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2024.01.011
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    Zs.A 229: Show issues Location:
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  4. Article ; Online: Role of splanchnic circulation in the pathogenesis of heart failure: State-of-the-art review.

    Yaku, Hidenori / Fudim, Marat / Shah, Sanjiv J

    Journal of cardiology

    2024  Volume 83, Issue 5, Page(s) 330–337

    Abstract: A hallmark of heart failure (HF), whether it presents itself during rest or periods of physical exertion, is the excessive elevation of intracardiac filling pressures at rest or with exercise. Many mechanisms contribute to the elevated intracardiac ... ...

    Abstract A hallmark of heart failure (HF), whether it presents itself during rest or periods of physical exertion, is the excessive elevation of intracardiac filling pressures at rest or with exercise. Many mechanisms contribute to the elevated intracardiac filling pressures, and notably, the concept of volume redistribution has gained attention as a cause of the elevated intracardiac filling pressures in patients with HF, particularly HF with preserved ejection fraction, who often present without symptoms at rest, with shortness of breath and fatigue appearing only during exertion. This phenomenon suggests cardiopulmonary system non-compliance and inappropriate volume distribution between the stressed and unstressed blood volume components. A substantial proportion of the intravascular blood volume is in the splanchnic vascular compartment in the abdomen. Preclinical and clinical investigations support the critical role of the sympathetic nervous system in modulating the capacitance and compliance of the splanchnic vascular bed via modulation of the greater splanchnic nerve (GSN). The GSN activation by stressors such as exercise causes excessive splanchnic vasoconstriction, which may contribute to the decompensation of chronic HF via volume redistribution from the splanchnic vascular bed to the central compartment. Accordingly, for example, GSN ablation for volume management has been proposed as a potential therapeutic intervention to increase unstressed blood volume. Here we provide a comprehensive review of the role of splanchnic circulation in the pathogenesis of HF and potential novel treatment options for redistributing blood volume to improve symptoms and prognosis in patients with HF.
    MeSH term(s) Humans ; Heart Failure/etiology ; Heart Failure/therapy ; Heart Failure/diagnosis ; Splanchnic Circulation ; Blood Volume ; Heart ; Sympathetic Nervous System ; Stroke Volume
    Language English
    Publishing date 2024-02-17
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 639364-0
    ISSN 1876-4738 ; 0386-2887 ; 0914-5087
    ISSN (online) 1876-4738
    ISSN 0386-2887 ; 0914-5087
    DOI 10.1016/j.jjcc.2024.02.004
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  5. Article ; Online: Shielding the Heart: Preload Reduction Therapies in Heart Failure.

    Khan, Muhammad Shahzeb / Tedford, Ryan J / Fudim, Marat

    JACC. Basic to translational science

    2023  Volume 8, Issue 4, Page(s) 403–405

    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Editorial
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2023.03.009
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  6. Article ; Online: Why Do Exercise Hemodynamics Matter?

    Caravita, Sergio / Baratto, Claudia / Fudim, Marat

    Journal of cardiac failure

    2023  Volume 29, Issue 9, Page(s) 1285–1287

    MeSH term(s) Humans ; Heart Failure ; Hemodynamics ; Exercise ; Exercise Test
    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.05.002
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  7. Article ; Online: Congestion and Inflammation in Heart Failure: Beyond the Chicken or the Egg.

    Kittipibul, Veraprapas / Fudim, Marat / Sobotka, Paul A

    Journal of cardiac failure

    2023  Volume 30, Issue 4, Page(s) 592–595

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Hospitalization ; Inflammation
    Language English
    Publishing date 2023-11-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.10.479
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  8. Article ; Online: Innovation During Cardiovascular Training: An Unmet Need.

    Shivakumar, Nishkala / Ngeno, Titus / Richardson, Eric / Fudim, Marat

    Journal of cardiac failure

    2023  Volume 29, Issue 12, Page(s) 1686–1688

    MeSH term(s) Humans ; Heart Failure ; Cardiovascular Diseases/therapy
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.09.001
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  9. Article ; Online: Tackling Inflammation in Heart Failure With Preserved Ejection Fraction: Resurrection of Vagus Nerve Stimulation?

    Kittipibul, Veraprapas / Fudim, Marat

    Journal of the American Heart Association

    2022  Volume 11, Issue 3, Page(s) e024481

    MeSH term(s) Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Inflammation ; Stroke Volume/physiology ; Vagus Nerve Stimulation
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.121.024481
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  10. Article ; Online: Implantable Hemodynamic-GUIDE Monitors: A CHAMPION Among Devices for Heart Failure.

    Fudim, Marat / Butler, Javed / Kittipibul, Veraprapas

    Journal of the American College of Cardiology

    2023  Volume 83, Issue 6, Page(s) 695–698

    MeSH term(s) Humans ; Pulmonary Artery ; Prostheses and Implants ; Hemodynamic Monitoring ; Hemodynamics ; Heart Failure/diagnosis ; Heart Failure/therapy ; Defibrillators, Implantable
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.12.008
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