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  1. Article ; Online: Association of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with the HLA-B75 serotype or HLA-B*15:21 allele in Filipino patients.

    Capule, Francis / Tragulpiankit, Pramote / Mahasirimongkol, Surakameth / Jittikoon, Jiraphun / Wichukchinda, Nuanjun / Theresa Alentajan-Aleta, Lara / James Barit, Jay-V / Casanova-Gutierrez, Josephine / Cabral-Lim, Leonor / Baltazar Reyes, Jose Paciano / Roa, Francisca / Salonga, Raymark / San Gabriel, Katrina Faith / Lynn Silao, Catherine

    The pharmacogenomics journal

    2020  Volume 20, Issue 3, Page(s) 533–541

    Abstract: A case-control study was conducted to investigate the association of HLA-A alleles, HLA-B alleles including HLA-B*15:02 and HLA-B75 serotype with carbamazepine-induced SJS/TEN in Filipino patients. A retrospective review of medical records was performed. ...

    Abstract A case-control study was conducted to investigate the association of HLA-A alleles, HLA-B alleles including HLA-B*15:02 and HLA-B75 serotype with carbamazepine-induced SJS/TEN in Filipino patients. A retrospective review of medical records was performed. Pertinent clinical data were collected. Eight (8) carbamazepine-induced SJS/TEN cases and 32 tolerant controls were recruited. Genomic DNA was extracted from the saliva samples and genotyping was performed by employing allele-specific polymerase chain reaction. Data were analyzed using the Fisher's exact test, Mann-Whitney U test, univariate logistic regression, and multivariate logistic regression. Single allele association analysis was done. The strength of association was expressed as odds ratio with 95% confidence interval. Positive predictive value, negative predictive value, sensitivity, and specificity were computed. Of all the alleles tested, the HLA-B75 serotype (p = 0.007, OR = 23.25, 95% CI = 2.33-232.21) and HLA-B*15:21 (p = 0.026, OR = 7.53, 95% CI = 1.27-44.79) were significantly associated with carbamazepine-induced SJS/TEN. The HLA-B75 serotype or HLA-B*15:21 allele may be used as a genetic risk assessment prior to prescription for prevention of carbamazepine-induced SJS/TEN in Filipino patients.
    MeSH term(s) Adult ; Alleles ; Anticonvulsants/adverse effects ; Asian Continental Ancestry Group/genetics ; Carbamazepine/adverse effects ; Case-Control Studies ; Female ; HLA-B Antigens/genetics ; Humans ; Male ; Middle Aged ; Philippines/epidemiology ; Serogroup ; Stevens-Johnson Syndrome/epidemiology ; Stevens-Johnson Syndrome/genetics ; Young Adult
    Chemical Substances Anticonvulsants ; HLA-B Antigens ; HLA-B75 antigen ; Carbamazepine (33CM23913M)
    Language English
    Publishing date 2020-01-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106831-8
    ISSN 1473-1150 ; 1470-269X
    ISSN (online) 1473-1150
    ISSN 1470-269X
    DOI 10.1038/s41397-019-0143-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Stevens-Johnson Syndrome and Acetazolamide.

    Kumar, Rajesh S / Tan, Donald T H / Yong-Ming, Por / Francis, Oen T / Sek-Tien, Hoh / Anand, Parthasarthy / Aung, Tin

    Journal of glaucoma

    2011  

    Language English
    Publishing date 2011-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 913494-3
    ISSN 1536-481X ; 1057-0829
    ISSN (online) 1536-481X
    ISSN 1057-0829
    DOI 10.1097/IJG.0b013e3181f7afe5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3795: Show issues Location:
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  3. Article ; Online: Carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis overlap in a Filipino with positive HLA-B75 serotype.

    Capule, Francis / Tragulpiankit, Pramote / Mahasirimongkol, Surakameth / Wichukchinda, Nuanjun / Jittikoon, Jiraphun / Alentajan-Aleta, Lara Theresa / James Barit, Jay-V / Casanova-Gutierrez, Josephine / Cabral-Lim, Leonor / Baltazar Reyes, Jose Paciano / Roa, Francisca / San Gabriel, Katrina Faith / Silao, Catherine Lynn

    BMJ case reports

    2018  Volume 2018

    Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two related mucocutaneous ...

    Abstract Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two related mucocutaneous disorders with different severities. Although the incidence is low, SJS and TEN are life-threatening and predominantly drug-induced conditions. There is a strong relationship between the
    MeSH term(s) Adult ; Antimanic Agents/adverse effects ; Carbamazepine/adverse effects ; HLA-B Antigens/blood ; Humans ; Male ; Mental Disorders/drug therapy ; Stevens-Johnson Syndrome/etiology ; Stevens-Johnson Syndrome/genetics
    Chemical Substances Antimanic Agents ; HLA-B Antigens ; HLA-B75 antigen ; Carbamazepine (33CM23913M)
    Language English
    Publishing date 2018-07-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2018-225028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Francis Johnson, architect

    Robinson, John Martin / Johnson, Francis / Neave, David

    a classical statement

    2001  

    Author's details John Martin Robinson and David Neave. Introd. by Giles Worsley
    Language English
    Size 312, Ill. (some col.), ports. (some col.), 29 cm.
    Publisher Oblong
    Publishing place Otley
    Document type Book
    Note Includes bibliographical references and index
    ISBN 0953657434 ; 9780953657438
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Article: Response to Johnson and Danhauer

    Kuk, Francis / Auriemmo, Jane

    Journal of the American Academy of Audiology

    2009  Volume 20, Issue 10, Page(s) 656–657

    Language English
    Publishing date 2009-11-01
    Publisher Thieme Medical Publishers
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1132599-9
    ISSN 2157-3107 ; 1050-0545
    ISSN (online) 2157-3107
    ISSN 1050-0545
    DOI 10.1055/s-0040-1715415
    Database Thieme publisher's database

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    Zs.A 3529: Show issues Location:
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  6. Article ; Online: Trimethoprim-sulfamethoxazole-induced Stevens-Johnson syndrome: a case report.

    Langlois, Michael R / Derk, Francis / Belczyk, Ronald / Zgonis, Thomas

    Journal of the American Podiatric Medical Association

    2010  Volume 100, Issue 4, Page(s) 299–303

    Abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis are rare; however, when they occur ... a unique case report of Stevens-Johnson syndrome and associated toxic epidermal necrolysis in a 61-year-old ...

    Abstract Stevens-Johnson syndrome and toxic epidermal necrolysis are rare; however, when they occur, they usually present with severe reactions in response to medications and other stimuli. These reactions are characterized by mucocutaneous lesions, which ultimately lead to epidermal death and sloughing. We present a unique case report of Stevens-Johnson syndrome and associated toxic epidermal necrolysis in a 61-year-old man after treatment for a peripherally inserted central catheter infection with trimethoprim-sulfamethoxazole. This case report reviews a rare adverse reaction to a commonly prescribed antibiotic drug used in podiatric medical practice for the management of diabetic foot infections.
    MeSH term(s) Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/adverse effects ; Diabetic Foot/drug therapy ; Humans ; Male ; Middle Aged ; Osteomyelitis/drug therapy ; Osteomyelitis/surgery ; Stevens-Johnson Syndrome/chemically induced ; Stevens-Johnson Syndrome/etiology ; Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage ; Trimethoprim, Sulfamethoxazole Drug Combination/adverse effects
    Chemical Substances Anti-Infective Agents ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2)
    Language English
    Publishing date 2010-07-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632622-5
    ISSN 1930-8264 ; 0003-0538 ; 8750-7315
    ISSN (online) 1930-8264
    ISSN 0003-0538 ; 8750-7315
    DOI 10.7547/1000299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Robust Machine-Learning Technique for Prediction of Late Mortality After Myocardial Injury in Noncardiac Surgery Patients.

    Johnson, Bijoy / Francis, Johnson

    The American journal of cardiology

    2023  Volume 204, Page(s) 428–429

    MeSH term(s) Humans ; Myocardial Ischemia ; Heart Injuries ; Postoperative Complications ; Risk Factors ; Surgical Procedures, Operative
    Language English
    Publishing date 2023-08-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2023.07.122
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  8. Book: Medical speech language pathology

    Johnson, Alex F. / Jacobson, Barbara H.

    a practitioner's guide

    2016  

    Title variant Medical speech-language pathology ; Medical speech language pathology
    Author's details Alex F. Johnson ; Barbara H. Jacobson
    Keywords Speech Disorders ; Language Disorders ; Deglutition Disorders ; Voice Disorders ; Speech-Language Pathology / methods
    Language English
    Size XIII, 378 S. : zahlr. Ill., 28 mm x 21.6 mm
    Edition 3. ed.
    Publisher Thieme
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT019157159
    ISBN 978-1-60406-395-0 ; 1-60406-395-5 ; 9781604063967 ; 1604063963
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2016 A 2428 available for loan (reading room) Lesesaal EG

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  9. Article ; Online: Association between

    Avery, Jade / Leak-Johnson, Tennille / Francis, Sharon C

    Genes

    2024  Volume 15, Issue 4

    Abstract: Obesity is a public health crisis, and its prevalence disproportionately affects African Americans in the United States. Dysregulation of organelle calcium homeostasis is associated with obesity. The mitochondrial calcium uniporter (: Methods: We used ...

    Abstract Obesity is a public health crisis, and its prevalence disproportionately affects African Americans in the United States. Dysregulation of organelle calcium homeostasis is associated with obesity. The mitochondrial calcium uniporter (
    Methods: We used an additive genetic model to assess the association between obesity traits (body mass index (BMI), waist and hip circumference) and selected
    Results: We observed three
    Conclusions: This study found associations of
    MeSH term(s) Humans ; Polymorphism, Single Nucleotide ; Obesity/genetics ; Female ; Male ; Adult ; Middle Aged ; Calcium Channels/genetics ; Body Mass Index ; United States/epidemiology ; Black or African American/genetics ; Genetic Predisposition to Disease ; White People/genetics
    Chemical Substances Calcium Channels ; mitochondrial calcium uniporter
    Language English
    Publishing date 2024-04-19
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes15040512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Supported decision-making interventions in mental healthcare: A systematic review of current evidence and implementation barriers.

    Francis, Cathy J / Johnson, Amanda / Wilson, Rhonda L

    Health expectations : an international journal of public participation in health care and health policy

    2024  Volume 27, Issue 2, Page(s) e14001

    Abstract: Background: There is a growing momentum around the world to foster greater opportunities for the involvement of mental health service users in their care and treatment planning. In-principle support for this aim is widespread across mental healthcare ... ...

    Abstract Background: There is a growing momentum around the world to foster greater opportunities for the involvement of mental health service users in their care and treatment planning. In-principle support for this aim is widespread across mental healthcare professionals. Yet, progress in mental health services towards this objective has lagged in practice.
    Objectives: We conducted a systematic review of quantitative, qualitative and mixed-method research on interventions to improve opportunities for the involvement of mental healthcare service users in treatment planning, to understand the current research evidence and the barriers to implementation.
    Methods: Seven databases were searched and 5137 articles were screened. Articles were included if they reported on an intervention for adult service users, were published between 2008 and October 2023 and were in English. Evidence in the 140 included articles was synthesised according to the JBI guidance on Mixed Methods Systematic Reviews.
    Results: Research in this field remains exploratory in nature, with a wide range of interventions investigated to date but little experimental replication. Overarching barriers to shared and supported decision-making in mental health treatment planning were (1) Organisational (resource limitations, culture barriers, risk management priorities and structure); (2) Process (lack of knowledge, time constraints, health-related concerns, problems completing and using plans); and (3) Relationship barriers (fear and distrust for both service users and clinicians).
    Conclusions: On the basis of the barriers identified, recommendations are made to enable the implementation of new policies and programs, the designing of new tools and for clinicians seeking to practice shared and supported decision-making in the healthcare they offer.
    Patient or public contribution: This systematic review has been guided at all stages by a researcher with experience of mental health service use, who does not wish to be identified at this point in time. The findings may inform organisations, researchers and practitioners on implementing supported decision-making, for the greater involvement of people with mental ill health in their healthcare.
    MeSH term(s) Humans ; Delivery of Health Care ; Health Facilities ; Health Personnel ; Mental Health ; Mental Health Services ; Clinical Decision-Making
    Language English
    Publishing date 2024-03-02
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2119434-8
    ISSN 1369-7625 ; 1369-6513
    ISSN (online) 1369-7625
    ISSN 1369-6513
    DOI 10.1111/hex.14001
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