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  1. Article: Ulster's Fulton Physicians.

    Robinson, David

    The Ulster medical journal

    2016  Volume 85, Issue 1, Page(s) 29–32

    MeSH term(s) Family/history ; History, 19th Century ; History, 20th Century ; Humans ; Ireland ; Physicians/history
    Language English
    Publishing date 2016-01
    Publishing country Northern Ireland
    Document type Historical Article ; Journal Article
    ZDB-ID 603342-8
    ISSN 2046-4207 ; 0041-6193
    ISSN (online) 2046-4207
    ISSN 0041-6193
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 217: Show issues Location:
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  2. Article: Sharp Excision and Electrocautery Dermabrasion in the Treatment of Rhinophyma.

    Cartwright, Jake K / Robinson, Fulton A / Dixon, Natalie R / Billington, Alicia R

    Eplasty

    2022  Volume 22, Page(s) ic7

    Abstract: What is rhinophyma? ...

    Abstract What is rhinophyma?
    Language English
    Publishing date 2022-05-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2412803-X
    ISSN 1937-5719
    ISSN 1937-5719
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  3. Article ; Online: Recurrent switch 2 domain RAC2 mutations in intravascular large B-cell lymphoma.

    Kodgule, Rohan / Chen, Jie / Khonde, Pooja / Robinson, Joshua / D'Albora, Amy / Cook, Lisa / Fronick, Catrina C / Fulton, Robert / Srivatsan, Sridhar Nonavinkere / Cimino, Patrick J / Duncavage, Eric J

    Blood advances

    2022  Volume 6, Issue 23, Page(s) 6051–6055

    MeSH term(s) Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Mutation
    Language English
    Publishing date 2022-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2022006985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7153: Show issues Location:
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  4. Article ; Online: Development of a Patient Activation Toolkit for Hepatitis C Virus Testing.

    Rivera Rivera, Jessica / Fuzzell, Lindsay N / Garcia, Jennifer / Rathwell, Julie / Robinson, Edmondo J / Chavez, Melody / Fulton, Hayden / Whitmer, Ashley / Mathew, Ebin / Giuliano, Anna R / Vadaparampil, Susan T

    Journal of cancer education : the official journal of the American Association for Cancer Education

    2022  Volume 38, Issue 3, Page(s) 931–939

    Abstract: We evaluated the acceptability of a patient activation toolkit for hepatitis C virus (HCV) testing amidst universal adult guidelines. We developed a patient-facing toolkit that included a letter to the patient from their healthcare provider, HCV ... ...

    Abstract We evaluated the acceptability of a patient activation toolkit for hepatitis C virus (HCV) testing amidst universal adult guidelines. We developed a patient-facing toolkit that included a letter to the patient from their healthcare provider, HCV factsheet, and question prompt list, which contained questions for their provider about HCV infection and testing. We conducted qualitative interviews with patients ages 18-78 (n = 17), using a semi-structured interview guide based on learner verification. We assessed attraction, comprehension, cultural-linguistic acceptability, self-efficacy, and persuasiveness of toolkit materials using direct content analysis. Participants reported materials were attractive, offering suggestions to improve readability. They reported some understanding of materials but requested use of less medical jargon, particularly for the factsheet. Participants discussed cultural acceptability and suggested ways to improve language inclusiveness and comfort with content, given stigma surrounding HCV risk factors. Participants reported that including a letter, factsheet, and QPL improved the persuasiveness of materials, and they conveyed their motivation to be tested for HCV. Results indicate preliminary acceptability for use of the patient activation toolkit, which will be refined based on participants' recommendations. Overall, this patient activation toolkit holds promise for increasing HCV testing rates.
    MeSH term(s) Adult ; Humans ; Hepacivirus ; Patient Participation ; Hepatitis C/diagnosis ; Hepatitis C/prevention & control ; Risk Factors ; Social Stigma
    Language English
    Publishing date 2022-08-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 632898-2
    ISSN 1543-0154 ; 0885-8195 ; 1543-1154
    ISSN (online) 1543-0154
    ISSN 0885-8195 ; 1543-1154
    DOI 10.1007/s13187-022-02209-0
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    Zs.A 2185: Show issues Location:
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  5. Article ; Online: Acute alcohol induces greater dose-dependent increase in the lateral cortical network functional connectivity in adult than adolescent rats.

    Lee, Sung-Ho / Shnitko, Tatiana A / Hsu, Li-Ming / Broadwater, Margaret A / Sardinas, Mabelle / Wang, Tzu-Wen Winnie / Robinson, Donita L / Vetreno, Ryan P / Crews, Fulton T / Shih, Yen-Yu Ian

    Addiction neuroscience

    2023  Volume 7

    Abstract: Alcohol misuse and, particularly adolescent drinking, is a major public health concern. While evidence suggests that adolescent alcohol use affects frontal brain regions that are important for cognitive control over behavior little is known about how ... ...

    Abstract Alcohol misuse and, particularly adolescent drinking, is a major public health concern. While evidence suggests that adolescent alcohol use affects frontal brain regions that are important for cognitive control over behavior little is known about how acute alcohol exposure alters large-scale brain networks and how sex and age may moderate such effects. Here, we employ a recently developed functional magnetic resonance imaging (fMRI) protocol to acquire rat brain functional connectivity data and use an established analytical pipeline to examine the effect of sex, age, and alcohol dose on connectivity within and between three major rodent brain networks: defaul mode, salience, and lateral cortical network. We identify the intra- and inter-network connectivity differences and establish moderation models to reveal significant influences of age on acute alcohol-induced lateral cortical network connectivity. Through this work, we make brain-wide isotropic fMRI data with acute alcohol challenge publicly available, with the hope to facilitate future discovery of brain regions/circuits that are causally relevant to the impact of acute alcohol use.
    Language English
    Publishing date 2023-06-02
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-3925
    ISSN (online) 2772-3925
    DOI 10.1016/j.addicn.2023.100105
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  6. Article: Deep aspirations: towards a sustainable offshore Blue Economy.

    Novaglio, Camilla / Bax, Narissa / Boschetti, Fabio / Emad, Gholam Reza / Frusher, Stewart / Fullbrook, Liam / Hemer, Mark / Jennings, Sarah / van Putten, Ingrid / Robinson, Lucy M / Spain, Erica / Vince, Joanna / Voyer, Michelle / Wood, Graham / Fulton, Elizabeth A

    Reviews in fish biology and fisheries

    2021  Volume 32, Issue 1, Page(s) 209–230

    Language English
    Publishing date 2021-01-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1498719-3
    ISSN 1573-5184 ; 0960-3166
    ISSN (online) 1573-5184
    ISSN 0960-3166
    DOI 10.1007/s11160-020-09628-6
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  7. Article ; Online: Enhanced trophic transfer of chlorpyrifos from resistant Hyalella azteca to inland silversides (Menidia beryllina) and effects on acetylcholinesterase activity and swimming performance at varying temperatures.

    Fuller, Neil / Huff Hartz, Kara E / Johanif, Nadhirah / Magnuson, Jason T / Robinson, Eleni K / Fulton, Corie A / Poynton, Helen C / Connon, Richard E / Lydy, Michael J

    Environmental pollution (Barking, Essex : 1987)

    2021  Volume 291, Page(s) 118217

    Abstract: Chlorpyrifos, an organophosphate (OP) insecticide, is prevalent in aquatic systems globally and is often implicated in aquatic toxicity during storm events. Chlorpyrifos induces toxicity by inhibition of acetylcholinesterase (AChE) activity, which has ... ...

    Abstract Chlorpyrifos, an organophosphate (OP) insecticide, is prevalent in aquatic systems globally and is often implicated in aquatic toxicity during storm events. Chlorpyrifos induces toxicity by inhibition of acetylcholinesterase (AChE) activity, which has been related to alterations to fish swimming performance. Resistance to organophosphate insecticides, including chlorpyrifos, is prevalent in populations of the epibenthic amphipod Hyalella azteca in areas with known OP exposure. Previous studies have demonstrated an elevated bioaccumulation potential of insecticide-resistant prey items, however the potential for trophic transfer of chlorpyrifos from OP-resistant prey items and associated neurotoxic effects in fish predators has not been studied. Consequently, the present study aimed to determine the potential for trophic transfer of chlorpyrifos from OP-resistant H. azteca to a known predator, the inland silverside, Menidia beryllina at two temperatures (18 and 23 °C) to simulate temperature changes associated with global climate change (GCC). Fish were fed either
    MeSH term(s) Acetylcholinesterase ; Amphipoda ; Animals ; Chlorpyrifos/toxicity ; Insecticides/analysis ; Swimming ; Temperature ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/toxicity
    Chemical Substances Insecticides ; Water Pollutants, Chemical ; Acetylcholinesterase (EC 3.1.1.7) ; Chlorpyrifos (JCS58I644W)
    Language English
    Publishing date 2021-09-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2021.118217
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    Zs.A 2599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Impact of adolescent intermittent ethanol exposure on interneurons and their surrounding perineuronal nets in adulthood.

    Dannenhoffer, Carol A / Gómez-A, Alexander / Macht, Victoria A / Jawad, Rayyanoor / Sutherland, Elizabeth Blake / Vetreno, Ryan P / Crews, Fulton T / Boettiger, Charlotte A / Robinson, Donita L

    Alcoholism, clinical and experimental research

    2022  Volume 46, Issue 5, Page(s) 759–769

    Abstract: Background: Binge alcohol exposure during adolescence results in long-lasting alterations in the brain and behavior. For example, adolescent intermittent ethanol (AIE) exposure in rodents results in long-term loss of functional connectivity among ... ...

    Abstract Background: Binge alcohol exposure during adolescence results in long-lasting alterations in the brain and behavior. For example, adolescent intermittent ethanol (AIE) exposure in rodents results in long-term loss of functional connectivity among prefrontal cortex (PFC) and striatal regions as well as a variety of neurochemical, molecular, and epigenetic alterations. Interneurons in the PFC and striatum play critical roles in behavioral flexibility and functional connectivity. For example, parvalbumin (PV) interneurons are known to contribute to neural synchrony and cholinergic interneurons contribute to strategy selection. Furthermore, extracellular perineuronal nets (PNNs) that surround some interneurons, particularly PV+ interneurons, further regulate cellular plasticity. The effect of AIE exposure on the expression of these markers within the PFC is not well understood.
    Methods: The present study tested the hypothesis that AIE exposure reduces the expression of PV+ and choline acetyltransferase (ChAT)+ interneurons in the adult PFC and striatum and increases the related expression of PNNs (marked by binding of Wisteria floribunda agglutinin lectin) in adulthood. Male rats were exposed to AIE (5 g/kg/day, 2-days-on/2-days-off, i.e., P25 to P54) or water (CON), and brain tissue was harvested in adulthood (>P80). Immunohistochemistry and co-immunofluorescence were used to assess the expression of ChAT, PV, and PNNs within the adult PFC and striatum following AIE exposure.
    Results: ChAT and PV interneuron densities in the striatum and PFC were unchanged after AIE exposure. However, PNN density in the PFC of AIE-exposed rats was greater than in CON rats. Moreover, significantly more PV neurons were surrounded by PNNs in AIE-exposed subjects than controls in both PFC subregions assessed: orbitofrontal cortex (CON = 34%; AIE = 40%) and medial PFC (CON = 10%; AIE = 14%).
    Conclusions: These findings indicate that, following AIE exposure, PV interneuron expression in the adult PFC and striatum is unaltered, while PNNs surrounding these neurons are increased. This increase in PNNs may restrict the plasticity of the ensheathed neurons, thereby contributing to impaired microcircuitry in frontostriatal connectivity and related behavioral impairments.
    MeSH term(s) Adolescent ; Adult ; Animals ; Ethanol/metabolism ; Extracellular Matrix/metabolism ; Humans ; Interneurons/metabolism ; Male ; Parvalbumins/metabolism ; Prefrontal Cortex/metabolism ; Rats
    Chemical Substances Parvalbumins ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2022-04-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 428999-7
    ISSN 1530-0277 ; 0145-6008
    ISSN (online) 1530-0277
    ISSN 0145-6008
    DOI 10.1111/acer.14810
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    Zs.A 1375: Show issues Location:
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  9. Article ; Online: Role of angiotensin-converting enzyme 2 and pericytes in cardiac complications of COVID-19 infection.

    Robinson, Fulton A / Mihealsick, Ryan P / Wagener, Brant M / Hanna, Peter / Poston, Megan D / Efimov, Igor R / Shivkumar, Kalyanam / Hoover, Donald B

    American journal of physiology. Heart and circulatory physiology

    2020  Volume 319, Issue 5, Page(s) H1059–H1068

    Abstract: The prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly reached pandemic proportions, and knowledge about this virus and coronavirus disease 2019 (COVID-19) has expanded rapidly. This review focuses primarily on mechanisms ... ...

    Abstract The prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly reached pandemic proportions, and knowledge about this virus and coronavirus disease 2019 (COVID-19) has expanded rapidly. This review focuses primarily on mechanisms that contribute to acute cardiac injury and dysfunction, which are common in patients with severe disease. The etiology of cardiac injury is multifactorial, and the extent is likely enhanced by preexisting cardiovascular disease. Disruption of homeostatic mechanisms secondary to pulmonary pathology ranks high on the list, and there is growing evidence that direct infection of cardiac cells can occur. Angiotensin-converting enzyme 2 (ACE2) plays a central role in COVID-19 and is a necessary receptor for viral entry into human cells. ACE2 normally not only eliminates angiotensin II (Ang II) by converting it to Ang-(1-7) but also elicits a beneficial response profile counteracting that of Ang II. Molecular analyses of single nuclei from human hearts have shown that ACE2 is most highly expressed by pericytes. Given the important roles that pericytes have in the microvasculature, infection of these cells could compromise myocardial supply to meet metabolic demand. Furthermore, ACE2 activity is crucial for opposing adverse effects of locally generated Ang II, so virus-mediated internalization of ACE2 could exacerbate pathology by this mechanism. While the role of cardiac pericytes in acute heart injury by SARS-CoV-2 requires investigation, expression of ACE2 by these cells has broader implications for cardiac pathophysiology.
    MeSH term(s) Angiotensin-Converting Enzyme 2 ; Animals ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/enzymology ; Coronavirus Infections/virology ; Heart Diseases/enzymology ; Heart Diseases/physiopathology ; Heart Diseases/virology ; Host-Pathogen Interactions ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pericytes/enzymology ; Pericytes/virology ; Pneumonia, Viral/enzymology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Virus Internalization
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-10-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 603838-4
    ISSN 1522-1539 ; 0363-6135
    ISSN (online) 1522-1539
    ISSN 0363-6135
    DOI 10.1152/ajpheart.00681.2020
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    Uc I Zs.89: Show issues Location:
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  10. Article: Deep aspirations: towards a sustainable offshore Blue Economy

    Novaglio, Camilla / Bax, Narissa / Boschetti, Fabio / Emad, Gholam Reza / Frusher, Stewart / Fullbrook, Liam / Hemer, Mark / Jennings, Sarah / van Putten, Ingrid / Robinson, Lucy M. / Spain, Erica / Vince, Joanna / Voyer, Michelle / Wood, Graham / Fulton, Elizabeth A.

    Reviews in fish biology and fisheries. 2022 Mar., v. 32, no. 1

    2022  

    Abstract: The ocean economy is experiencing rapid growth that will provide benefits but will also pose environmental and social risks. With limited space and degraded resources in coastal areas, offshore waters will be a particular focus of Blue Economy expansion ... ...

    Abstract The ocean economy is experiencing rapid growth that will provide benefits but will also pose environmental and social risks. With limited space and degraded resources in coastal areas, offshore waters will be a particular focus of Blue Economy expansion over the next decade. When emerging and established economic sectors expand in offshore waters (within national Exclusive Economic Zones), different potential Blue Economy opportunities and challenges will arise. Following a series of interdisciplinary workshops, we imagine two technically possible futures for the offshore Blue Economy and we identify the actions required to achieve the more sustainable outcome. Under a business as usual scenario the focus will remain on economic growth, the commodification of nature, the dominance of private over public and cultural interests, and prioritisation of the interests of current over future generations. A more sustainable scenario would meet multiple UN Sustainable Development Goals and ensure inclusive economic developments, environmental sustainability, and fair and equitable access to resources and technologies across users, nations, and generations. Challenges to this more sustainable future are a lack of infrastructure and technology to support emerging offshore sectors, limited understanding of environmental impacts, inequitable outcomes, and a lack of planning and governmental oversight. Addressing these challenges will require a shift in societal values, a more balanced allocation of funding to offshore activities, transparency in information sharing between industries and across nations, and adjustment of international legal and institutional mechanisms. The sustainable and equitable offshore Blue Economy we envisage is achievable and provides a unique opportunity to build global capacity and partnership.
    Keywords fish ; infrastructure ; prioritization ; sustainable development
    Language English
    Dates of publication 2022-03
    Size p. 209-230.
    Publishing place Springer International Publishing
    Document type Article
    ZDB-ID 1498719-3
    ISSN 1573-5184 ; 0960-3166
    ISSN (online) 1573-5184
    ISSN 0960-3166
    DOI 10.1007/s11160-020-09628-6
    Database NAL-Catalogue (AGRICOLA)

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