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Article: Use of Tumguide® in the Insertion of a Nasogastric Tube Into the Stomach of a Patient With Creutzfeldt-Jakob Disease in a Nursing Home: A Case Report.

Iida, Tomoya / Kodama, Yumi / Kogina, Kazue

2024 Volume 16, Issue 1, Page(s) e52082

Abstract: A 77-year-old woman exhibited a rapid progression of dementia and declining physical function and, over a period of about four months, reached a state of akinetic mutism. A final diagnosis of Creutzfeldt-Jakob disease (CJD) was made. A nasogastric tube ... ...

Abstract	A 77-year-old woman exhibited a rapid progression of dementia and declining physical function and, over a period of about four months, reached a state of akinetic mutism. A final diagnosis of Creutzfeldt-Jakob disease (CJD) was made. A nasogastric tube was inserted into the stomach, and then it was confirmed on X-ray that the end of the tube was in the correct position. She was discharged to a nursing home, where she received home medical care after discharge. One month after the nasogastric tube insertion, Tumguide® was used to assist in replacing the tube at this home. In home care settings where an X-ray machine may not be available, Tumguide® may assist with nasogastric tube insertion.
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52082
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Article ; Online: Switching nanoscale temperature fields with high-order plasmonic modes in transition metal nanorods.

Setoura, Kenji / Tamura, Mamoru / Oshikiri, Tomoya / Iida, Takuya

RSC advances

2023 Volume 13, Issue 49, Page(s) 34489–34496

Abstract: Depending on the photoirradiation conditions, metal nanostructures exhibit various plasmonic modes, including dipolar, quadrupolar, and hexapolar modes. This work demonstrates numerically that these high-order plasmonic modes can be used to switch ... ...

Abstract	Depending on the photoirradiation conditions, metal nanostructures exhibit various plasmonic modes, including dipolar, quadrupolar, and hexapolar modes. This work demonstrates numerically that these high-order plasmonic modes can be used to switch nanoscale temperature distributions during the plasmonic heating of a manganese (Mn) nanorod. The key feature of Mn is its low thermal conductivity. Generally, when noble metal nanostructures are used for plasmonic heating, the nanostructure surface will be almost isothermal regardless of the order of the excited plasmonic modes because of the high thermal conductivity of noble metals,
Language	English
Publishing date	2023-11-24
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra06649e
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Article ; Online: Purification/Amplification-Free RNA Detection Platform for Rapid and Multiplex Diagnosis of Plant Viral Infections.

Ueda, Tomoya / Shinoda, Hajime / Makino, Asami / Yoshimura, Mami / Iida, Tatsuya / Watanabe, Rikiya

Analytical chemistry

2023 Volume 95, Issue 25, Page(s) 9680–9686

Abstract: Genetic tests are highly sensitive, and quantitative methods for diagnosing human viral infections, including COVID-19, are also being used to diagnose plant diseases in various agricultural settings. Conventional genetic tests for plant viruses are ... ...

Abstract	Genetic tests are highly sensitive, and quantitative methods for diagnosing human viral infections, including COVID-19, are also being used to diagnose plant diseases in various agricultural settings. Conventional genetic tests for plant viruses are mostly based on methods that require purification and amplification of viral genomes from plant samples, which generally take several hours in total, making it difficult to use them in rapid detection at point-of-care testing (POCT). In this study, we developed Direct-SATORI, a rapid and robust genetic test that eliminates the purification and amplification processes of viral genomes by extending the recently developed amplification-free digital RNA detection platform called SATORI, allowing the detection of various plant viral genes in a total of less than 15 min with a limit of detection (LoD) of 98 ∼ copies/μL using tomato viruses as an example. In addition, the platform can simultaneously detect eight plant viruses directly from ∼1 mg of tomato leaves with a sensitivity of 96% and a specificity of 99%. Direct-SATORI can be applied to various infections related to RNA viruses, and its practical use is highly anticipated as a versatile platform for plant disease diagnostics in the future.
MeSH term(s)	Humans ; RNA ; COVID-19 ; Plant Viruses/genetics ; Limit of Detection ; RNA, Viral/genetics ; Sensitivity and Specificity ; Nucleic Acid Amplification Techniques/methods ; COVID-19 Testing
Chemical Substances	RNA (63231-63-0) ; RNA, Viral
Language	English
Publishing date	2023-06-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.3c01691
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Article ; Online: Detection of aspiration from images of a videofluoroscopic swallowing study adopting deep learning.

Iida, Yukihiro / Näppi, Janne / Kitano, Tomoya / Hironaka, Toru / Katsumata, Akitoshi / Yoshida, Hiroyuki

Oral radiology

2023 Volume 39, Issue 3, Page(s) 553–562

Abstract: Objectives: A videofluoroscopic swallowing study (VFSS) is conducted to detect aspiration. However, aspiration occurs within a short time and is difficult to detect. If deep learning can detect aspirations with high accuracy, clinicians can focus on the ...

Abstract	Objectives: A videofluoroscopic swallowing study (VFSS) is conducted to detect aspiration. However, aspiration occurs within a short time and is difficult to detect. If deep learning can detect aspirations with high accuracy, clinicians can focus on the diagnosis of the detected aspirations. Whether VFSS aspirations can be classified using rapid-prototyping deep-learning tools was studied. Methods: VFSS videos were separated into individual image frames. A region of interest was defined on the pharynx. Three convolutional neural networks (CNNs), namely a Simple-Layer CNN, Multiple-Layer CNN, and Modified LeNet, were designed for the classification. The performance results of the CNNs were compared in terms of the areas under their receiver-operating characteristic curves (AUCs). Results: A total of 18,333 images obtained through data augmentation were selected for the evaluation. The different CNNs yielded sensitivities of 78.8%-87.6%, specificities of 91.9%-98.1%, and overall accuracies of 85.8%-91.7%. The AUC of 0.974 obtained for the Simple-Layer CNN and Modified LeNet was significantly higher than that obtained for the Multiple-Layer CNN (AUC of 0.936) (p < 0.001). Conclusions: The results of this study show that deep learning has potential for detecting aspiration with high accuracy.
MeSH term(s)	Deglutition ; Deep Learning ; Fluoroscopy/methods ; Neural Networks, Computer ; Area Under Curve
Language	English
Publishing date	2023-02-08
Publishing country	Japan
Document type	Journal Article
ZDB-ID	639456-5
ISSN	1613-9674 ; 0911-6028
ISSN (online)	1613-9674
ISSN	0911-6028
DOI	10.1007/s11282-023-00669-8
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Article ; Online: Pt

Kawawaki, Tokuhisa / Mitomi, Yusuke / Nishi, Naoki / Kurosaki, Ryuki / Oiwa, Kazutaka / Tanaka, Tomoya / Hirase, Hinoki / Miyajima, Sayuri / Niihori, Yoshiki / Osborn, D J / Koitaya, Takanori / Metha, Gregory F / Yokoyama, Toshihiko / Iida, Kenji / Negishi, Yuichi

Nanoscale

2023 Volume 15, Issue 16, Page(s) 7272–7279

Abstract: We recently found that [ ... ...

Abstract	We recently found that [Pt
Language	English
Publishing date	2023-04-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr01152f
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Article ; Online: Purification/Amplification-Free RNA Detection Platform for Rapid and Multiplex Diagnosis of Plant Viral Infections

Ueda, Tomoya / Shinoda, Hajime / Makino, Asami / Yoshimura, Mami / Iida, Tatsuya / Watanabe, Rikiya

Analytical Chemistry. 2023 June 12, v. 95, no. 25 p.9680-9686

2023

Abstract	Genetic tests are highly sensitive, and quantitative methods for diagnosing human viral infections, including COVID-19, are also being used to diagnose plant diseases in various agricultural settings. Conventional genetic tests for plant viruses are mostly based on methods that require purification and amplification of viral genomes from plant samples, which generally take several hours in total, making it difficult to use them in rapid detection at point-of-care testing (POCT). In this study, we developed Direct-SATORI, a rapid and robust genetic test that eliminates the purification and amplification processes of viral genomes by extending the recently developed amplification-free digital RNA detection platform called SATORI, allowing the detection of various plant viral genes in a total of less than 15 min with a limit of detection (LoD) of 98 ∼ copies/μL using tomato viruses as an example. In addition, the platform can simultaneously detect eight plant viruses directly from ∼1 mg of tomato leaves with a sensitivity of 96% and a specificity of 99%. Direct-SATORI can be applied to various infections related to RNA viruses, and its practical use is highly anticipated as a versatile platform for plant disease diagnostics in the future.
Keywords	COVID-19 infection ; RNA ; analytical chemistry ; detection limit ; diagnostic techniques ; humans ; point-of-care systems ; rapid methods ; tomatoes ; viral genome
Language	English
Dates of publication	2023-0612
Size	p. 9680-9686.
Publishing place	American Chemical Society
Document type	Article ; Online
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.3c01691
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A Rare Cause of Ileus in a Middle-Aged Japanese Woman.

Iida, Tomoya / Arimura, Yoshiaki / Nakase, Hiroshi

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

2019 Volume 18, Issue 4, Page(s) e43

MeSH term(s)	Female ; Humans ; Ileus/diagnostic imaging ; Ileus/etiology ; Intestinal Obstruction ; Japan ; Middle Aged
Language	English
Publishing date	2019-02-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2119789-1
ISSN	1542-7714 ; 1542-3565
ISSN (online)	1542-7714
ISSN	1542-3565
DOI	10.1016/j.cgh.2019.02.034
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Article ; Online: Deep learning for preliminary profiling of panoramic images.

Kohinata, Kiyomi / Kitano, Tomoya / Nishiyama, Wataru / Mori, Mizuho / Iida, Yukihiro / Fujita, Hiroshi / Katsumata, Akitoshi

Oral radiology

2022 Volume 39, Issue 2, Page(s) 275–281

Abstract: Objective: This study explored the feasibility of using deep learning for profiling of panoramic radiographs.: Study design: Panoramic radiographs of 1000 patients were used. Patients were categorized using seven dental or physical characteristics: ... ...

Abstract	Objective: This study explored the feasibility of using deep learning for profiling of panoramic radiographs. Study design: Panoramic radiographs of 1000 patients were used. Patients were categorized using seven dental or physical characteristics: age, gender, mixed or permanent dentition, number of presenting teeth, impacted wisdom tooth status, implant status, and prosthetic treatment status. A Neural Network Console (Sony Network Communications Inc., Tokyo, Japan) deep learning system and the VGG-Net deep convolutional neural network were used for classification. Results: Dentition and prosthetic treatment status exhibited classification accuracies of 93.5% and 90.5%, respectively. Tooth number and implant status both exhibited 89.5% classification accuracy; impacted wisdom tooth status exhibited 69.0% classification accuracy. Age and gender exhibited classification accuracies of 56.0% and 75.5%, respectively. Conclusion: Our proposed preliminary profiling method may be useful for preliminary interpretation of panoramic images and preprocessing before the application of additional artificial intelligence techniques.
MeSH term(s)	Humans ; Artificial Intelligence ; Deep Learning ; Neural Networks, Computer ; Radiography, Panoramic ; Tooth, Impacted
Language	English
Publishing date	2022-06-27
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639456-5
ISSN	1613-9674 ; 0911-6028
ISSN (online)	1613-9674
ISSN	0911-6028
DOI	10.1007/s11282-022-00634-x
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Article ; Online: Extraction of terminal ileal lipomas to cecum can facilitate endoscopic resection: A case series with video.

Yamazaki, Hiroshi / Minato, Yohei / Madhu, Deepak / Iida, Toshifumi / Banjyoya, Susumu / Kimura, Tomoya / Furuta, Koichi / Nagae, Shinya / Itou, Yohei / Takeuchi, Nao / Takayanagi, Shunya / Kimoto, Yoshiaki / Kano, Yuki / Sakuno, Takashi / Ono, Kohei / Ohata, Ken

DEN open

2024 Volume 5, Issue 1, Page(s) e375

Abstract: Large ileal lipomas over 2 cm can cause symptoms, that may require a resection. Due to the narrow lumen and thin walls of the ileum, endoscopic treatments can have a high risk of adverse events and require technical expertise, thus surgical resection is ... ...

Abstract	Large ileal lipomas over 2 cm can cause symptoms, that may require a resection. Due to the narrow lumen and thin walls of the ileum, endoscopic treatments can have a high risk of adverse events and require technical expertise, thus surgical resection is currently the mainstay of treatment. To overcome the technical challenges, we developed a novel method to endoscopically resect terminal ileal lipomas. The technique involves extracting the lesion into the cecum, which creates sufficient space to maneuver, and a better field of view. The lipoma is resected with endoscopic mucosal resection or endoscopic submucosal dissection. The appearance of the lipoma protruding out of the ileocecal valve resembles that of a tongue sticking out of the mouth, thus we named this the "tongue out technique". To assess the technical feasibility of this method, we retrospectively analyzed seven cases of terminal ileal lipoma that were endoscopically resected using the "tongue out technique" at NTT Medical Center Tokyo between January 2017 and October 2023. Technical success was 100% and en bloc resection was achieved in all cases. The median size was 31 (14-55) mm. Three cases were resected with endoscopic mucosal resection while endoscopic submucosal dissection was performed on the other four cases. There was one case of delayed post-endoscopic mucosal resection bleeding, which was caused by clip dislodgement. There were no perforations. No recurrence of the lipoma or associated symptoms have been observed. This new technique can allow more ileal lipomas to be treated with minimally invasive and organ-preserving endoscopic procedures.
Language	English
Publishing date	2024-04-30
Publishing country	Australia
Document type	Journal Article
ISSN	2692-4609
ISSN (online)	2692-4609
DOI	10.1002/deo2.375
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Article ; Online: Coexistence of growth hormone, adrenocorticotropic hormone, and testosterone deficiency associated with coronavirus disease 2019: a case followed up for 15 months.

Yoshimura, Kai / Yamamoto, Masaaki / Inoue, Tomoya / Fukuoka, Hidenori / Iida, Keiji / Ogawa, Wataru

Endocrine journal

2022 Volume 69, Issue 11, Page(s) 1335–1342

Abstract: Coronavirus disease 2019 (COVID-19) is associated with endocrine disorders, but their long-term clinical course remains unclear. We here report the 15-month clinical course for an individual with multiple endocrine disorders of the pituitary gland and ... ...

Abstract	Coronavirus disease 2019 (COVID-19) is associated with endocrine disorders, but their long-term clinical course remains unclear. We here report the 15-month clinical course for an individual with multiple endocrine disorders of the pituitary gland and testis likely triggered by COVID-19. A 65-year-old man with no history of endocrinopathy was admitted for acute COVID-19 pneumonia. Although his respiratory condition improved after administration of antiviral drugs, his blood pressure dropped suddenly to a preshock level and was refractory to vasopressors. The circulating adrenocorticotropic hormone (ACTH) and cortisol concentrations were low, and secondary adrenal insufficiency was suspected. Administration of hydrocortisone rapidly ameliorated the hypotension, and the patient was discharged taking 15 mg of hydrocortisone daily. An insulin tolerance test performed 3 months later revealed impaired ACTH, cortisol, and growth hormone (GH) responses, indicative of combined hypopituitarism. The patient also manifested symptoms of hypogonadism, and a hormonal workup suggested primary hypogonadism. At 12 months after discharge, GH and ACTH responses had recovered completely and partially, respectively. After another 3 months, basal ACTH and cortisol levels had been restored to the normal range and the patient discontinued hydrocortisone replacement without exacerbation of symptoms, although his hypogonadism persisted. The patient thus developed transient GH and ACTH deficiency that lasted for more than a year as well as persistent primary hypogonadism during intensive care for COVID-19. Certain prolonged symptoms of COVID-19 might be accounted for by such hormonal disturbance.
MeSH term(s)	Male ; Humans ; Aged ; Adrenocorticotropic Hormone ; Growth Hormone ; Hydrocortisone/therapeutic use ; COVID-19/complications ; COVID-19/drug therapy ; Human Growth Hormone/therapeutic use ; Hypogonadism ; Testosterone
Chemical Substances	Adrenocorticotropic Hormone (9002-60-2) ; Growth Hormone (9002-72-6) ; Hydrocortisone (WI4X0X7BPJ) ; Human Growth Hormone (12629-01-5) ; Testosterone (3XMK78S47O)
Language	English
Publishing date	2022-07-14
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	1151918-6
ISSN	1348-4540 ; 0918-8959
ISSN (online)	1348-4540
ISSN	0918-8959
DOI	10.1507/endocrj.EJ22-0108
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