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  1. Article: Dietary protein restriction and blood-pressure control in chronic renal insufficiency

    Lemann, J. Jr

    New England journal of medicine. Aug 11, 1994. v. 331 (6)

    1994  

    Keywords renal failure ; dietary protein ; protein intake ; blood pressure ; chronic diseases ; amino acids ; experimental diets ; men ; women ; longitudinal studies ; dietary supplements
    Language English
    Dates of publication 1994-0811
    Size p. 405-406.
    Document type Article
    Note Discussion of the article "The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease" by S. Klahr, A.S. Levey, G.J. Beck et al, this journal v. 330, p. 877-884, 1994. Further discussion by T. Shiigai, H. Nonoguchi and S. Fishbane, p. 405. Reply by S. Klahr, A.S. Levey and G.J. Beck, p. 405-406.
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Relationship between Urinary Calcium and Net Acid Excretion as Determined by Dietary Protein and Potassium: A Review

    Lemann Jr., Jacob

    Nephron

    1998  Volume 81, Issue 1, Page(s) 18–25

    Abstract: Increasing urinary net acid (titratable acid + NH4 – HCO3) excretion is accompanied by an increased urinary Ca excretion because of reduced renal tubular reabsorption of filtered Ca. The relationships between urinary Ca excretion rates and urinary net ... ...

    Institution Nephrology Section, Tulane University School of Medicine, New Orleans, La., USA
    Abstract Increasing urinary net acid (titratable acid + NH4 – HCO3) excretion is accompanied by an increased urinary Ca excretion because of reduced renal tubular reabsorption of filtered Ca. The relationships between urinary Ca excretion rates and urinary net acid excretion rates are reviewed for data: (1) among healthy adults eating constant diets when net acid excretion is increased by increasing dietary protein, administering NH4Cl, or withdrawal of dietary KHCO3 or reduced by administering KHCO3; (2) among healthy adults eating constant diets providing varying amounts of protein and potassium, and (3) among healthy adults and Ca stone formers with and without idiopathic hypercalciuria eating ad libitum. The results show that urinary Ca excretion varies directly with net acid excretion by 0.035 mmol/mEq. The urinary net acid excretion increases by 0.10–0.15 mEq/mmol urinary urea, and urinary Ca increases by about 0.04 mmol/g dietary protein, while the urinary net acid excretion decreases as the ratio of urinary K/urea, a reflection of the dietary K relative to dietary protein, increases. The relationships between net acid excretion and both urinary urea and K/urea are similar among Ca stone formers without and with idiopathic hypercalciuria, but those with idiopathic hypercalciuria exhibit increased rates of urinary Ca excretion at all levels of net acid excretion.
    Keywords Dietary potassium ; Dietary protein ; Net acid excretion ; Urinary calcium
    Language English
    Publishing date 1998-12-24
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Paper
    ZDB-ID 207121-6
    ISBN 978-3-8055-6818-0 ; 978-3-318-00390-1 ; 3-8055-6818-5 ; 3-318-00390-5
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000046294
    Database Karger publisher's database

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  3. Article: Potassium causes calcium retention in healthy adults

    Lemann, J. Jr / Pleuss, J.A / Gray, R.W

    Journal of nutrition. Sept 1993. v. 123 (9)

    1993  

    Abstract: The administration of 60 mmol/d of KHCO3 to healthy adults reduced urinary calcium excretion by 0.9 mmol/d and caused calcium balance to become equivalently more positive. Other studies showed that 90 mmol/d of KHCO3 reduced both daily and fasting ... ...

    Abstract The administration of 60 mmol/d of KHCO3 to healthy adults reduced urinary calcium excretion by 0.9 mmol/d and caused calcium balance to become equivalently more positive. Other studies showed that 90 mmol/d of KHCO3 reduced both daily and fasting urinary calcium excretion rates, whereas deprivation of either KCl or KHCO3, using synthetic diets, was accompanied by increased daily and fasting urinary calcium excretion rates. A significant inverse relationship between the changes in urinary calcium and the changes in urinary potassium was observed: delta urinary Ca (mmol/d) = 0.29 - 0.015 delta urinary K (mmol/ d); r = -0.65. Correlative evaluation of additional data suggested that the fall in urinary calcium during potassium administration may be related to the natriuretic effects of potassium, resulting in ECF-volume contraction or to potassium-induced phosphate retention and suppress on of calcitriol synthesis, or to both mechanisms.
    Keywords calcium ; potassium ; mineral metabolism ; urine ; excretion ; nutrient-nutrient interactions ; men ; dietary mineral supplements
    Language English
    Dates of publication 1993-09
    Size p. 1623-1626.
    Document type Article
    Note Paper presented at the "3rd Annual Workshop of Nutrition and Bone Health Group," October 3, 1992, Minneapolis, Minnesota.
    ZDB-ID 218373-0
    ISSN 1541-6100 ; 0022-3166
    ISSN (online) 1541-6100
    ISSN 0022-3166
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: A normal dietary calcium intake or hydrochlorothiazide inhibits bone resorption when serum 1,25-(OH)2-D levels are elevated

    Lemann, J. Jr / Gray, R.W / Maierhofer, W.J / Cheung, H.S

    Vitamin D : chemical, biochemical, and clinical update ; proceedings of the Sixth Workshop on Vitamin D, Merano, Italy, March 1985 / editors, A.W. Norman ... [et al.].

    1985  

    Keywords humans ; calcium ; diet ; bone resorption ; calcitriol ; hydrochlorothiazide
    Language English
    Size p. 485-486.
    Publisher De Gruyter, 1985.
    Publishing place Berlin [West Ger.]
    Document type Article
    ISBN 3111010815 ; 9783111010816
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Effects of weight loss on serum 1,25-(OH2)-vitamin D concentrations in adults: a preliminary report

    Lemann, J. Jr / Gray, R.W / Maierhofer, W.J / Adams, N.D

    Calcified tissue international. Mar 1984. v. 36 (2)

    1984  

    Title variant Effects of weight loss on serum 1,25-(OH2)-vitamin D concentrations in adults: a preliminary report [Caloric intake]
    Keywords energy intake
    Language English
    Dates of publication 1984-03
    Size p. 139-144., ill.
    Document type Article
    ZDB-ID 304266-2
    ISSN 1432-0827 ; 0944-0747 ; 0008-0594 ; 0171-967X
    ISSN (online) 1432-0827
    ISSN 0944-0747 ; 0008-0594 ; 0171-967X
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  6. Article: Liquid formula diets reduce serum 1,25-(OH)2-vitamin D concentrations in humans

    Lemann, J. Jr / Adams, N.D / Gray, R.W

    Vitamin D, chemical, biochemical, and clinical endocrinology of calcium metabolism : proceedings of the Fifth Workshop on Vitamin D, Williamsburg, VA, USA, February 1982 / editors, A.W. Norman ... [et al.].

    1982  

    Keywords nutrition physiology ; human nutrition
    Language English
    Size p. 669-675.
    Publisher W. de Gruyter, 1982.
    Publishing place Berlin [West Germany]
    Document type Article
    ISBN 3110088649 ; 9783110088649
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Vitamin D metabolism in patients with nephrolithiasis

    Lemann, J. Jr / Gray, R.W / Adams, N.D

    Vitamin D : basic research and its clinical application : proceedings of the Fourth Workshop on Vitamin D, Berlin, West Germany, February 1979. editors, A. W. Norman ... [et al.].

    1979  

    Keywords human nutrition ; diet-related diseases
    Language English
    Size p. 957-962., ill.
    Publisher W. de Gruyter, 1979.
    Publishing place Berlin; New York
    Document type Article
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Akinetic mutism in a bone marrow transplant recipient following total-body irradiation and amphotericin B chemoprophylaxis. A positron emission tomographic and neuropathologic study.

    Devinsky, O / Lemann, W / Evans, A C / Moeller, J R / Rottenberg, D A

    Archives of neurology

    1987  Volume 44, Issue 4, Page(s) 414–417

    Abstract: We describe a case of akinetic mutism associated with diffuse cerebral leukoencephalopathy, which developed in a bone marrow transplant recipient following total-body irradiation and amphotericin B chemoprophylaxis. A trial of high-dose bromocriptine did ...

    Abstract We describe a case of akinetic mutism associated with diffuse cerebral leukoencephalopathy, which developed in a bone marrow transplant recipient following total-body irradiation and amphotericin B chemoprophylaxis. A trial of high-dose bromocriptine did not stimulate purposeful verbal or motor activity. Fluorine 18-fluorodeoxyglucose/positron emission tomographic studies, performed before and during bromocriptine therapy, demonstrated cerebral hypometabolism and treatment-related decreases in regional cerebral blood volume. We conclude that whole-brain or total-body irradiation may increase blood-brain barrier permeability to polyene antibiotics, and that high-dose therapy with dopamine agonists is unlikely to benefit patients with akinetic mutism due to diffuse white-matter lesions.
    MeSH term(s) Adult ; Akinetic Mutism/etiology ; Akinetic Mutism/metabolism ; Akinetic Mutism/pathology ; Amphotericin B/adverse effects ; Anemia, Aplastic/therapy ; Bone Marrow Transplantation ; Bromocriptine/therapeutic use ; Cerebrovascular Circulation ; Deoxyglucose/analogs & derivatives ; Fluorodeoxyglucose F18 ; Glucose/metabolism ; Humans ; Male ; Tomography, Emission-Computed ; Whole-Body Irradiation/adverse effects
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Bromocriptine (3A64E3G5ZO) ; Amphotericin B (7XU7A7DROE) ; Deoxyglucose (9G2MP84A8W) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 1987-04
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 80049-1
    ISSN 1538-3687 ; 0003-9942
    ISSN (online) 1538-3687
    ISSN 0003-9942
    DOI 10.1001/archneur.1987.00520160048013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.191: Show issues Location:
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  9. Article ; Online: Studies of the Acute Effects of Aldosterone and Cortisol on the Interrelationship Between Renal Sodium, Calcium and Magnesium Excretion in Normal Man

    Lemann, Jr.,, J. / Piering, W. F. / Lennon, E. J.

    Nephron

    1970  Volume 7, Issue 2, Page(s) 117–130

    Abstract: 1. Sodium, calcium and magnesium reabsorption by the renal tubules are interrelated. 2. To determine whether the tubular transport of calcium and magnesium were influenced directly by adrenocortical hormones, clearance studies were carried out in normal ... ...

    Abstract 1. Sodium, calcium and magnesium reabsorption by the renal tubules are interrelated. 2. To determine whether the tubular transport of calcium and magnesium were influenced directly by adrenocortical hormones, clearance studies were carried out in normal adults before and after the administration of either a placebo, aldosterone or cortisol. 3. During the placebo studies urinary sodium and chloride excretion increased while potassium and net acid excretion were unaltered. 4. Following aldosterone infusion, sodium and chloride excretion fell while potassium and net acid excretion rose. 5. After cortisol infusion sodium excretion also fell but was accompanied only by a rise in potassium excretion. 6. Despite the observed changes in sodium excretion, neither placebo, aldosterone nor cortisol administration had any effect on the serum ultrafiltrate concentrations, rates of glomerular filtration or urinary excretion rates of calcium or magnesium. 7. We conclude that aldosterone and cortisol have no direct effect on renal tubular reabsorption of calcium or magnesium.
    Language English
    Publisher S. Karger AG
    Publishing place Basel
    Publishing country Switzerland
    Document type Article ; Online
    ZDB-ID 207121-6
    ISSN 1423-0186 ; 0028-2766 ; 1660-8151 ; 0028-2766 ; 1660-8151
    ISSN (online) 1423-0186
    ISSN 0028-2766 ; 1660-8151
    DOI 10.1159/000179814
    Database Karger publisher's database

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  10. Article: The regulation of plasma 1,25-(OH)2-D concentrations in healthy adults

    Gray, R.W / Lemann, J. Jr / Adams, N.D

    Vitamin D : basic research and its clinical application : proceedings of the Fourth Workshop on Vitamin D, Berlin, West Germany, February 1979. editors, A. W. Norman ... [et al.].

    1979  

    Title variant Regulation of plasma 1,25-(OH)2-D [dihydroxyvitamin] concentrations in healthy adults
    Keywords nutrition physiology ; human nutrition
    Language English
    Size p. 545-551., ill.
    Publisher W. de Gruyter, 1979.
    Publishing place Berlin; New York
    Document type Article
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