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  1. Article ; Online: Male Accessory Breast Cancer Successfully Treated With Single-Agent Trastuzumab: A Case Report.

    Ji, Wencai / Guo, Wenbin

    American journal of men's health

    2023  Volume 17, Issue 3, Page(s) 15579883231171010

    Abstract: Male accessory breast cancer is an extremely rare tumor. There is no report about its monotherapy and subsequent outcome prior to 2022. The current study presents the case of a 76-year-old male patient with a hard mass in the left axilla. Histopathologic ...

    Abstract Male accessory breast cancer is an extremely rare tumor. There is no report about its monotherapy and subsequent outcome prior to 2022. The current study presents the case of a 76-year-old male patient with a hard mass in the left axilla. Histopathologic examination of an excisional specimen indicated an adenocarcinoma compatible with breast carcinoma. Immunohistochemical analysis demonstrated that the mass was estrogen receptor (ER) (-), progesterone receptor (PR)(-), and human epidermal growth factor receptor type 2 (HER2) (-). A diagnosis of breast cancer originating from the accessory mammary gland in the axilla was made. Two years following surgery, the patient presented with a pulmonary lesion. Core needle biopsy was performed, and the lesion was found to be ER (-), PR(-), and HER2 (3+). The patient was successfully treated with single-agent trastuzumab. Single-agent trastuzumab could be a reasonable regimen for metastatic accessory breast cancer patients with HER2 overexpression for whom chemotherapy and endocrine therapy are not suitable.
    MeSH term(s) Humans ; Male ; Aged ; Trastuzumab/therapeutic use ; Breast Neoplasms ; Breast Neoplasms, Male/drug therapy ; Breast Neoplasms, Male/surgery
    Chemical Substances Trastuzumab (P188ANX8CK)
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2275106-3
    ISSN 1557-9891 ; 1557-9883
    ISSN (online) 1557-9891
    ISSN 1557-9883
    DOI 10.1177/15579883231171010
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  2. Article ; Online: The Crystallization and Melting Behavior of Neodymium-Based Butadiene Rubber Blends.

    Li, Xiaofan / Zhang, Xiaohu / Ji, Huan / Wei, Yanxing / Xie, Xinzheng / Zhu, Wenbin / Bi, Jifu

    Polymers

    2024  Volume 16, Issue 3

    Abstract: This study investigates the influence of poly(butadiene-isoprene) copolymer rubber (BIR) and TDAE oil on the crystallization and melting behavior of neodymium-based butadiene rubber (Nd-BR). The study demonstrates that the melting points of Nd-BR and its ...

    Abstract This study investigates the influence of poly(butadiene-isoprene) copolymer rubber (BIR) and TDAE oil on the crystallization and melting behavior of neodymium-based butadiene rubber (Nd-BR). The study demonstrates that the melting points of Nd-BR and its blends decrease with lower crystallization temperatures. Below the critical crystallization temperature (
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16030342
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  3. Article ; Online: SGMS1-AS1/MicroRNA-106a-5p/CPT2 Axis as a Novel Target for Regulating Lactate Metabolism in Colon Cancer.

    Ruochen, Yan / Wenbin, Ji / Chao, Gao / Yuhua, Yuan / Feng, Qi

    Technology in cancer research & treatment

    2023  Volume 22, Page(s) 15330338231212071

    Abstract: Purpose: The malignant transformation of cells can lead to aerobic glycolysis, an important form of metabolic reprogramming in colon cancer cells, which can cause the accumulation of lactate and accelerate the proliferation of tumor cells also enhance ... ...

    Abstract Purpose: The malignant transformation of cells can lead to aerobic glycolysis, an important form of metabolic reprogramming in colon cancer cells, which can cause the accumulation of lactate and accelerate the proliferation of tumor cells also enhance their chemotherapy drug resistance. The aim of this study was to investigate the possible molecular mechanisms responsible for the increased lactate expression in colon cancer.
    Methods: Several bioinformatics methods, including differential analysis, gene ontology enrichment, univariate and multivariate Cox regression analysis were used to find the lactic acid-related gene carnitine palmitoyltransferase 2. We analyzed the relationship between carnitine palmitoyltransferase 2 and clinical features as well as immune microenvironment. To further explore the mechanism of carnitine palmitoyltransferase 2 in colon cancer, we performed methylation analysis and constructed a competitive endogenous RNA network, which was validated in cell lines and clinical specimens.
    Results: We used bioinformatics to select the lactic acid-related gene carnitine palmitoyltransferase 2 and found low expression of carnitine palmitoyltransferase 2 was associated with poor prognosis in colon cancer. An inhibitory tumor microenvironment was created when carnitine palmitoyltransferase 2 expression was reduced, with decreased CD4 T cells, CD8 T cells, dendritic cells, and B cells but increased cancer-associated fibroblasts. Methylation analysis showed that the abnormal decrease in carnitine palmitoyltransferase 2 might be caused by hypermethylation. We constructed a network of SGMS1-AS1/microRNA-106a-5p/carnitine palmitoyltransferase 2 and verified their expression in cell lines and clinical specimens.
    Conclusion: Our work revealed the possible mechanism of lactate accumulation in colon cancer and explored a new potential treatment for colon cancer by cutting off aerobic glycolysis in tumor cells.
    MeSH term(s) Humans ; Carnitine O-Palmitoyltransferase/genetics ; Carnitine O-Palmitoyltransferase/metabolism ; Cell Transformation, Neoplastic ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Lactic Acid ; Membrane Proteins ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Nerve Tissue Proteins ; Transferases (Other Substituted Phosphate Groups) ; Tumor Microenvironment/genetics
    Chemical Substances Carnitine O-Palmitoyltransferase (EC 2.3.1.21) ; Lactic Acid (33X04XA5AT) ; Membrane Proteins ; MicroRNAs ; Nerve Tissue Proteins ; SGMS1 protein, human (EC 2.7.8.-) ; Transferases (Other Substituted Phosphate Groups) (EC 2.7.8.-) ; MIRN106 microRNA, human
    Language English
    Publishing date 2023-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2146365-7
    ISSN 1533-0338 ; 1533-0346
    ISSN (online) 1533-0338
    ISSN 1533-0346
    DOI 10.1177/15330338231212071
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5871: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Study on the Crystallization Behavior of Neodymium Rare-Earth Butadiene Rubber Blends and Its Effect on Dynamic Mechanical Properties.

    Zhang, Xiaohu / Zhu, Wenbin / Li, Xiaofan / Xie, Xinzheng / Ji, Huan / Wei, Yanxing / Bi, Jifu

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 1

    Abstract: Utilizing neodymium-based butadiene rubber as a baseline, this study examines the effect of eco-friendly aromatic TDAE oil, fillers, and crosslinking reactions on neodymium-based rare-earth butadiene rubber (Nd-BR) crystallization behavior. The findings ... ...

    Abstract Utilizing neodymium-based butadiene rubber as a baseline, this study examines the effect of eco-friendly aromatic TDAE oil, fillers, and crosslinking reactions on neodymium-based rare-earth butadiene rubber (Nd-BR) crystallization behavior. The findings suggest that TDAE oil hinders crystallization, resulting in decreased crystallization temperatures and heightened activation energies (
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17010256
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  5. Article ; Online: 20 µm Micro-LEDs Mass Transfer via Laser-Induced In Situ Nanoparticles Resonance Enhancement.

    Sun, Weigao / Ji, Lingfei / Lin, Zhenyuan / Zhang, Litian / Wang, Zhiyong / Qin, Wenbin / Yan, Tianyang

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2309877

    Abstract: Ultrafast laser is expected as a promising strategy for micro-LEDs (µ-LEDs) transfer due to its inherent property of suppressing thermal effects. However, its ultrahigh peak power and the unclear transfer mechanism make its transfer quality and ... ...

    Abstract Ultrafast laser is expected as a promising strategy for micro-LEDs (µ-LEDs) transfer due to its inherent property of suppressing thermal effects. However, its ultrahigh peak power and the unclear transfer mechanism make its transfer quality and efficiency unsatisfactory. Here, the study reports the high-precision mass transfer of 20 µm fine-pitch µ-LEDs via in situ nanoparticles (NPs) resonance enhancement in burst mode ultraviolet picosecond laser irradiation. This technique suppresses the thermal melting effect and rapid cooling behavior of plasma by temporal modulation of the burst mode, generating NPs-induced resonance enhancement that accurately and controllable drives a single unit up to tens of thousands of µ-LEDs. The transfer of large µ-LED arrays with more than 180 000 chips is also demonstrated, showing a transfer yield close to 99.9%, a transfer speed of 700 pcs s
    Language English
    Publishing date 2024-02-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202309877
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  6. Article: Recent Advances in Broadband Photodetectors from Infrared to Terahertz.

    Si, Wei / Zhou, Wenbin / Liu, Xiangze / Wang, Ke / Liao, Yiming / Yan, Feng / Ji, Xiaoli

    Micromachines

    2024  Volume 15, Issue 4

    Abstract: The growing need for the multiband photodetection of a single scene has promoted the development of both multispectral coupling and broadband detection technologies. Photodetectors operating across the infrared (IR) to terahertz (THz) regions have many ... ...

    Abstract The growing need for the multiband photodetection of a single scene has promoted the development of both multispectral coupling and broadband detection technologies. Photodetectors operating across the infrared (IR) to terahertz (THz) regions have many applications such as in optical communications, sensing imaging, material identification, and biomedical detection. In this review, we present a comprehensive overview of the latest advances in broadband photodetectors operating in the infrared to terahertz range, highlighting their classification, operating principles, and performance characteristics. We discuss the challenges faced in achieving broadband detection and summarize various strategies employed to extend the spectral response of photodetectors. Lastly, we conclude by outlining future research directions in the field of broadband photodetection, including the utilization of novel materials, artificial microstructure, and integration schemes to overcome current limitations. These innovative methodologies have the potential to achieve high-performance, ultra-broadband photodetectors.
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15040427
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  7. Article ; Online: Simulation study on assist-as-needed control of a rehabilitation robotic walker.

    Wang, Wenbin / Gong, Tao / Song, Zhendong / Wang, Zhifeng / Ji, Jiancheng

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2023  Volume 31, Issue S1, Page(s) 293–302

    Abstract: Background: Along with China entering an aging society, the percentage of people that over 60 will reach 34.9% in 2050, resulted in a significant increase in stroke patients.: Objective: This paper proposes a rehabilitation robotic walker for walking ...

    Abstract Background: Along with China entering an aging society, the percentage of people that over 60 will reach 34.9% in 2050, resulted in a significant increase in stroke patients.
    Objective: This paper proposes a rehabilitation robotic walker for walking assistance during the daily life, and a control method for the motor relearning during the gait training. The walker consists of an omni-directional mobile platform (OMP) which ensures the walker can move on the ground, a body weight support system (BWS) which is capable of providing the desired unloading force, and a pelvic assist mechanism (PAM) to provide the user with four degrees of freedom and avoid the rigid impact. The study goal is to gain a better understanding of the assist-as-needed control strategy during the gait training.
    Methods: For the man-machine interaction control, the assist-as-needed control strategy is adopted to guide the users' motions and improve the interaction experience. To build the force field in the three-dimensional space, the dynamics of the system is derived to increase the accuracy of force control.
    Results: The simulation results show that the force field around the motion trajectory was generated in the three-dimensional space. In order to understand the force field, we designed the simulation on sagittal plane and the controller can generate the appropriate force field. The preliminary experiment results were consistent with the simulation results.
    Conclusion: Based on the mathematical simulation and the preliminary test, the results demonstrate that the proposed system can provide the guide force around the target trajectory, the accuracy of force control still remains to be improved.
    MeSH term(s) Humans ; Walking ; Gait ; Robotic Surgical Procedures ; Walkers ; Robotics ; Stroke Rehabilitation
    Language English
    Publishing date 2023-05-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-236025
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3846: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: In Situ Polymerized Quasi-Solid Electrolytes Compounded with Ionic Liquid Empowering Long-Life Cycling of 4.45 V Lithium-Metal Battery.

    Ma, Shuo / Zhang, Donghui / Tang, Zhongli / Li, Wenbin / Zhang, Yanan / Zhang, Yating / Ji, Kemeng / Chen, Mingming

    ACS applied materials & interfaces

    2024  

    Abstract: High-voltage resistant quasi-solid-state polymer electrolytes (QSPEs) are promising for enhancing the energy density of lithium-metal batteries in practice. However, side reactions occurring at the interfaces between the anodes or cathodes and QSPEs ... ...

    Abstract High-voltage resistant quasi-solid-state polymer electrolytes (QSPEs) are promising for enhancing the energy density of lithium-metal batteries in practice. However, side reactions occurring at the interfaces between the anodes or cathodes and QSPEs considerably reduce the lifespan of high-voltage LMBs. In this study, a copolymer of vinyl ethylene carbonate (VEC) and poly(ethylene glycol) diacrylate (PEGDA) was used as the framework, with a cellulose membrane (CE) as the supporting layer. Based on density functional theory calculations, 1-butyl-1-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide (Pyr
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c00866
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  9. Article ; Online: Effect of Dilution on the Crystallization Kinetics of Neodymium-Based Rare Earth Polybutadiene Rubber.

    Zhang, Xiaohu / Li, Xiaofan / Zhu, Wenbin / Xie, Xinzheng / Ji, Huan / Bi, Jifu

    Polymers

    2023  Volume 16, Issue 1

    Abstract: The crystallization behavior of neodymium-based rare earth polybutadiene rubber (Nd-BR) is studied in the presence of small-molecule treated distillate aromatic extract (TDAE) and high-molecular-weight polybutadiene-isoprene copolymer rubber (BIR). ... ...

    Abstract The crystallization behavior of neodymium-based rare earth polybutadiene rubber (Nd-BR) is studied in the presence of small-molecule treated distillate aromatic extract (TDAE) and high-molecular-weight polybutadiene-isoprene copolymer rubber (BIR). Pronounced inhibitory effects on the crystallization of Nd-BR are exhibited by both materials, as evidenced by reductions in the crystallization temperature (
    Language English
    Publishing date 2023-12-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16010035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: 18

    Xu, Xiaojun / Sun, Xun / Ma, Ling / Zhang, Huangqi / Ji, Wenbin / Xia, Xiaotian / Lan, Xiaoli

    Frontiers in oncology

    2023  Volume 13, Page(s) 1149791

    Abstract: Introduction: This study aimed to investigate the feasibility of predicting progression-free survival (PFS) in breast cancer patients using pretreatment : Methods: Breast cancer patients who underwent : Results: Eleven radiomics features were ... ...

    Abstract Introduction: This study aimed to investigate the feasibility of predicting progression-free survival (PFS) in breast cancer patients using pretreatment
    Methods: Breast cancer patients who underwent
    Results: Eleven radiomics features were selected to generate rad-score. The clinical model comprised three parameters: clinical M stage, CA125, and pathological N stage. Rad-score and clinical-model were significantly associated with PFS in the training set (
    Conclusion: The ICR model, which combined clinical parameters and preoperative
    Language English
    Publishing date 2023-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1149791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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