LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 515

Search options

  1. Book ; Thesis: Laborchemische Auffälligkeiten des Schilddrüsenhormonstatus bei Patienten mit eingeschränkter Nierenfunktion

    Peters, Juliane / Kreißl, Michael / Walz, Gerd

    2021  

    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details von Juliane Peters ; Gutachter: Prof. Dr. Michael Kreißl ; Prof. Dr. Gerd Walz
    Keywords Chronische Niereninsuffizienz ; Schilddrüsenfunktion
    Subject Chronisches Nierenversagen ; Chronische Nierenfunktionsstörung
    Language German
    Size 2 ungezählte Blätter, IV, 57 Blätter, Diagramme
    Publisher Otto-von-Guericke-Universität Magdeburg
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Magdeburg, 2022
    HBZ-ID HT021694321
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 E 102 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Conference proceedings: II. Intensivkurs Nieren- und Hochdruckkrankheiten der Akademie Niere

    Walz, Gerd

    21. - 25. Mai 2007, Münster

    2007  

    Title variant Zweiter Intensivkurs Nieren- und Hochdruckkrankheiten der Akademie Niere
    Institution Akademie für Fort- und Weiterbildung Nieren- und Hochdruckkrankheiten
    Event/congress Intensivkurs Nieren- und Hochdruckkrankheiten (2, 2007, MünsterWestf)
    Author's details Akademie Niere (Hrsg.) [Autorinnen und Autoren Gerd Walz ...]
    Keywords Nierenkrankheit ; Hypertonie
    Subject Arterielle Hypertonie ; Arterieller Hochdruck ; Bluthochdruck ; Hochdruck ; Hypertension ; Hypertonus ; Nephropathie ; Nierenerkrankung ; Nierenerkrankungen ; Niere ; Renopathie
    Subject code 616.132 ; 616.61
    Language German
    Size 414 S. : Ill., graph. Darst.
    Publisher Pabst
    Publishing place Lengerich u.a.
    Publishing country Germany ; Austria ; United States
    Document type Book ; Conference proceedings
    Note Literaturangaben
    HBZ-ID HT015436599
    ISBN 978-3-89967-391-3 ; 3-89967-391-3
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 1427 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Role of primary cilia in non-dividing and post-mitotic cells.

    Walz, Gerd

    Cell and tissue research

    2017  Volume 369, Issue 1, Page(s) 11–25

    Abstract: The essential role of primary (non-motile) cilia during the development of multi-cellular tissues and organs is well established and is underlined by severe disease manifestations caused by mutations in cilia-associated molecules that are collectively ... ...

    Abstract The essential role of primary (non-motile) cilia during the development of multi-cellular tissues and organs is well established and is underlined by severe disease manifestations caused by mutations in cilia-associated molecules that are collectively termed ciliopathies. However, the role of primary cilia in non-dividing and terminally differentiated, post-mitotic cells is less well understood. Although the prevention of cells from re-entering the cell cycle may represent a major chore, primary cilia have recently been linked to DNA damage responses, autophagy and mitochondria. Given this connectivity, primary cilia in non-dividing cells are well positioned to form a signaling hub outside of the nucleus. Such a center could integrate information to initiate responses and to maintain cellular homeostasis if cell survival is jeopardized. These more discrete functions may remain undetected until differentiated cells are confronted with emergencies.
    Language English
    Publishing date 2017-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 125067-x
    ISSN 1432-0878 ; 0302-766X
    ISSN (online) 1432-0878
    ISSN 0302-766X
    DOI 10.1007/s00441-017-2599-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.94: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Effect of Cyclophosphamide and Glucocorticoid Therapy in IgA Nephropathy: A Single-Center Retrospective Analysis.

    Beck, Nicolas / Walz, Gerd / Schneider, Johanna

    Kidney360

    2022  Volume 3, Issue 3, Page(s) 506–515

    Abstract: Background: IgA nephropathy (IgAN) is the most common primary glomerulonephritis in adults, which causes ESKD in ≤45% of patients in the long term. The optimal therapeutic approach remains undetermined. In this study, we report the results of a single- ... ...

    Abstract Background: IgA nephropathy (IgAN) is the most common primary glomerulonephritis in adults, which causes ESKD in ≤45% of patients in the long term. The optimal therapeutic approach remains undetermined. In this study, we report the results of a single-center retrospective analysis of patients with IgAN.
    Methods: We retrospectively evaluated the therapeutic approach and outcome of all patients at our center with biopsy-proven IgAN between 2000 and 2020, focusing on the effect of intravenous cyclophosphamide therapy combined with glucocorticoids ("immunosuppressive therapy group"). The control group received standard supportive care.
    Results: Patients in the immunosuppressive therapy group had worse kidney function before the initiation of therapy, as indicated by higher serum creatinine, more proteinuria, and a higher degree of hematuria than the control group; they also displayed a higher body mass index. The Oxford classification of IgA nephropathy (MEST-C score) suggested more inflammatory activity in the immunosuppressive therapy group, including more crescents and endocapillary hypercellularity. During the follow-up, proteinuria and hematuria decreased in both groups, and to a significantly greater extent in the immunosuppressive therapy group. Cyclophosphamide treatment significantly improved kidney function as determined by the fold-change of eGFR during the observation period. The number of infections and hospitalizations did not differ, but the incidence of diabetes was increased in the immunosuppressive therapy group.
    Conclusions: This study suggests immunosuppressive therapy with cyclophosphamide combined with glucocorticoids improves kidney function, proteinuria, and hematuria. The therapy was safe for infectious complications, but was associated with an increased incidence of diabetes, which might be attributable in part to the use of steroids in patients with a higher body mass index at baseline. Although immunosuppressive therapy in IgAN remains controversial, our findings suggest that at least some patients benefit from more aggressive therapy.
    MeSH term(s) Adult ; Cyclophosphamide/adverse effects ; Glomerular Filtration Rate ; Glomerulonephritis, IGA/drug therapy ; Glucocorticoids/adverse effects ; Hematuria/etiology ; Humans ; Immunosuppressive Agents/adverse effects ; Kidney Failure, Chronic/complications ; Proteinuria/drug therapy ; Retrospective Studies
    Chemical Substances Glucocorticoids ; Immunosuppressive Agents ; Cyclophosphamide (8N3DW7272P)
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0006702021
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book ; Online ; Thesis: <dc:title>Mutations in TBC1D8B affect Rab11-activity and cause nephrotic syndrome</dc:title>

    Kampf, Lina L. [Verfasser] / Hermle, Tobias Franz [Akademischer Betreuer] / Walz, Gerd [Akademischer Betreuer] / Walz, Gerd [Sonstige] / Simons, Matias [Sonstige]

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book ; Online ; Thesis: <dc:title>Using transgenic Drosophila model to study the mechanism of APOL1-associated cytotoxicity</dc:title>

    Chen, Mengmeng [Verfasser] / Walz, Gerd [Akademischer Betreuer] / Hermle, Tobias Franz [Akademischer Betreuer] / Walz, Gerd [Sonstige] / Sekula, Peggy [Sonstige]

    2022  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Ruptured Intrarenal Arterial Aneurysm in a Patient With Granulomatosis With Polyangiitis.

    Schneider, Johanna / Venhoff, Nils / Walz, Gerd

    The Journal of rheumatology

    2021  Volume 48, Issue 4, Page(s) 615

    MeSH term(s) Aneurysm, Ruptured/diagnostic imaging ; Granulomatosis with Polyangiitis/complications ; Granulomatosis with Polyangiitis/drug therapy ; Humans
    Language English
    Publishing date 2021-07-08
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.190986
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 135: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Non-antigen-specific Immunoadsorption Is a Risk Factor for Severe Postoperative Infections in ABO-Incompatible Kidney Transplant Recipients.

    Matuschik, Laura / Seifert, Gabriel / Lammich, Katrin / Holzner, Philipp / Tanriver, Yakup / Fichtner-Feigl, Stefan / Walz, Gerd / Schneider, Johanna / Jänigen, Bernd

    Transplant international : official journal of the European Society for Organ Transplantation

    2024  Volume 37, Page(s) 12263

    Abstract: ABO-incompatible (ABOi) living kidney transplantation (KTx) is an established procedure to address the demand for kidney transplants with outcomes comparable to ABO-compatible KTx. Desensitization involves the use of immunoadsorption (IA) to eliminate ... ...

    Abstract ABO-incompatible (ABOi) living kidney transplantation (KTx) is an established procedure to address the demand for kidney transplants with outcomes comparable to ABO-compatible KTx. Desensitization involves the use of immunoadsorption (IA) to eliminate preformed antibodies against the allograft. This monocentric retrospective study compares single-use antigen-selective Glycosorb
    MeSH term(s) Humans ; Kidney Transplantation/adverse effects ; Kidney Transplantation/methods ; Retrospective Studies ; ABO Blood-Group System ; Blood Group Incompatibility ; Risk Factors ; Graft Rejection ; Graft Survival ; Living Donors
    Chemical Substances ABO Blood-Group System
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2024.12263
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2358: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Risk Factors and Management of Leukopenia After Kidney Transplantation: A Single-Center Experience.

    Henningsen, Max / Jaenigen, Bernd / Zschiedrich, Stefan / Pisarski, Przemyslaw / Walz, Gerd / Schneider, Johanna

    Transplantation proceedings

    2021  Volume 53, Issue 5, Page(s) 1589–1598

    Abstract: Background: Leukopenia is a common complication after kidney transplantation. The etiology is multifactorial, with medication adverse effects and cytomegalovirus infection as main causes. Optimal strategies to prevent or treat posttransplant leukopenia ... ...

    Abstract Background: Leukopenia is a common complication after kidney transplantation. The etiology is multifactorial, with medication adverse effects and cytomegalovirus infection as main causes. Optimal strategies to prevent or treat posttransplant leukopenia remain unknown. We aimed to identify risk factors for leukopenia and to investigate the benefit of switching the immunosuppressive therapy to hydrocortisone as a continuous infusion.
    Methods: We retrospectively evaluated all patients with leukopenia after kidney transplantation between 2007 and 2017 at our center relative to age- and sex-matched controls.
    Results: Leukopenia was associated with the degree of rejection therapy before leukopenia, the immunosuppressive therapy before transplantation, and an induction therapy with rabbit antithymocyte globulin. Patients with leukopenia exhibited increased mortality, an increased incidence of bacterial and viral infections, and more acute rejections. Switching to hydrocortisone as a continuous infusion in patients with severe leukopenia decreased the duration of leukopenia and the incidence of subsequent viral infections, especially with cytomegalovirus.
    Conclusion: Leukopenia is a risk factor for infectious complications and mortality, and it is associated with acute rejection. Switching immunosuppressive therapy to hydrocortisone as a continuous infusion is a safe approach to reduce the duration of leukopenia and the incidence of viral infections.
    Language English
    Publishing date 2021-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2021.04.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 835: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Role of primary cilia in non-dividing and post-mitotic cells

    Walz, Gerd

    Cell and tissue research. 2017 July, v. 369, no. 1

    2017  

    Abstract: The essential role of primary (non-motile) cilia during the development of multi-cellular tissues and organs is well established and is underlined by severe disease manifestations caused by mutations in cilia-associated molecules that are collectively ... ...

    Abstract The essential role of primary (non-motile) cilia during the development of multi-cellular tissues and organs is well established and is underlined by severe disease manifestations caused by mutations in cilia-associated molecules that are collectively termed ciliopathies. However, the role of primary cilia in non-dividing and terminally differentiated, post-mitotic cells is less well understood. Although the prevention of cells from re-entering the cell cycle may represent a major chore, primary cilia have recently been linked to DNA damage responses, autophagy and mitochondria. Given this connectivity, primary cilia in non-dividing cells are well positioned to form a signaling hub outside of the nucleus. Such a center could integrate information to initiate responses and to maintain cellular homeostasis if cell survival is jeopardized. These more discrete functions may remain undetected until differentiated cells are confronted with emergencies.
    Keywords DNA damage ; autophagy ; cell cycle ; cell viability ; chemical elements ; cilia ; homeostasis ; mitochondria ; mutation ; tissues
    Language English
    Dates of publication 2017-07
    Size p. 11-25.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 125067-x
    ISSN 1432-0878 ; 0302-766X
    ISSN (online) 1432-0878
    ISSN 0302-766X
    DOI 10.1007/s00441-017-2599-7
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 46/352: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top