Article ; Online: O
2021 Volume 9, Issue 3, Page(s) e0039921
Abstract: Escherichia coli K1 causes bacteremia and meningitis in human neonates. The K1 capsule, an α2,8-linked polysialic acid (PSA) homopolymer, is its essential virulence factor. PSA is usually partially modified ... ...
Abstract | Escherichia coli K1 causes bacteremia and meningitis in human neonates. The K1 capsule, an α2,8-linked polysialic acid (PSA) homopolymer, is its essential virulence factor. PSA is usually partially modified by |
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MeSH term(s) | Acetylation ; Animals ; Bacterial Capsules/immunology ; Escherichia coli/genetics ; Escherichia coli/immunology ; Escherichia coli Infections/genetics ; Escherichia coli Infections/immunology ; Escherichia coli Infections/microbiology ; Host-Pathogen Interactions ; Humans ; Immune Evasion ; Immunity, Innate ; Lysosomes/immunology ; Lysosomes/microbiology ; Male ; Mice ; Sialic Acid Binding Immunoglobulin-like Lectins/genetics ; Sialic Acid Binding Immunoglobulin-like Lectins/immunology ; Sialic Acids/immunology ; Vacuoles/immunology ; Vacuoles/microbiology |
Chemical Substances | Sialic Acid Binding Immunoglobulin-like Lectins ; Sialic Acids ; polysialic acid |
Language | English |
Publishing date | 2021-12-08 |
Publishing country | United States |
Document type | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2807133-5 |
ISSN | 2165-0497 ; 2165-0497 |
ISSN (online) | 2165-0497 |
ISSN | 2165-0497 |
DOI | 10.1128/spectrum.00399-21 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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