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  1. Article ; Online: Effect of Taichi Chuan on health-related physical fitness in adults: A systematic review with meta-analysis.

    Qi, Fengmeng / Soh, Kim Geok / Nasiruddin, Nasnoor Juzaily Mohd / Leong, Ong Swee / He, Sun / Liu, Huange

    Complementary therapies in medicine

    2023  Volume 77, Page(s) 102971

    Abstract: Purpose: Taichi Chuan was previously shown to benefit physical health, but the results were ... the effectiveness of Taichi Chuan and the mechanism by which it improves the physical health of adults.: Methods ... Chuan is beneficial to physical fitness, but not all indices supported this statement. Specifically ...

    Abstract Purpose: Taichi Chuan was previously shown to benefit physical health, but the results were inconsistent. The main reason is that the mechanism is not clear and may be interpreted differently. In this systematic review, we analyzed the data obtained from various randomized controlled trials to identify the effectiveness of Taichi Chuan and the mechanism by which it improves the physical health of adults.
    Methods: We systematically searched various databases, including PubMed, Web of Science, Scopus, Embase, EBSCO Host, Science Direct, CNKI, Wan-Fang, and VPCS, and obtained 1448 articles for review. The articles were selected following the PICO eligibility criteria. We performed a systematic review and meta-analysis to interpret the results of the different studies.
    Results: We included 16 studies in the systematic review. Six of them were of very high quality, ten were of acceptable quality. Overall, the results showed that Taichi Chuan is beneficial to physical fitness, but not all indices supported this statement. Specifically, the effects were significant on Balance (ES = - 0.33; P = 0.02), BMI (ES = - 0.83; P < 0.00001), body fat (ES = - 0.45; P < 0.00001), and vital capacity (ES = 23.39; P = 0.01). However, there were no significant effects on systolic blood pressure (ES = 0.07; P = 0.94) and diastolic blood pressure (ES = 0.03; P = 0.97).
    Conclusion: We found sufficient high-quality evidence to suggest that Taichi Chuan affects balance, BMI, body fat, vital capacity, and flexibility (sit-reach) in adults. The mechanism can be explained by low posture (balance) and moderate intensity of Taichi Chuan. However, no study has explained how to maintain concentration while keeping a dynamic low posture, which made it difficult to validate the finding that Taichi Chuan can reduce sympathetic tension under stress. In this study, we assumed that relaxation methods, which work on the central nervous system that links the body and the mind, might be the key explanation. However, further studies based on scientific, replicable methods need to be performed to confirm our findings.
    MeSH term(s) Humans ; Adult ; Physical Fitness ; Blood Pressure ; Relaxation Therapy
    Language English
    Publishing date 2023-08-14
    Publishing country Scotland
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 1155895-7
    ISSN 1873-6963 ; 0965-2299
    ISSN (online) 1873-6963
    ISSN 0965-2299
    DOI 10.1016/j.ctim.2023.102971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of aerobic exercise or Tai Chi Chuan interventions on problematic mobile phone use and the potential role of intestinal flora: A multi-arm randomized controlled trial.

    Zhang, Kexin / Guo, Haiyun / Zhang, Xueqing / Yang, Huayu / Yuan, Guojing / Zhu, Zhihui / Lu, Xiaoyan / Zhang, Jianghui / Du, Jun / Shi, Haiyan / Jin, Guifang / Ren, Juan / Hao, Jiahu / Sun, Ying / Su, Puyu / Zhang, Zhihua

    Journal of psychiatric research

    2024  Volume 170, Page(s) 394–407

    Abstract: ... assigned to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or ...

    Abstract Background: Problematic use of mobile phones (PMPU) has been described as a serious public health issue.
    Methods: This study was a parallel three-arm randomized controlled trial and has completed registration (ClinicalTrials.gov Identifier: NCT05843591). Ninety college students with PMPU were randomly assigned to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or the wait-list control group (WLC group, n = 30). At the end of the intervention, stool samples from the study participants were collected for biological analysis based on 16 S rDNA amplicon sequencing technology. The primary outcome was addiction symptoms assessed by the Smartphone Addiction Scale-Short Version (SAS-SV). The secondary outcomes are emotional symptoms, physical symptoms, and flora species.
    Results: Compared with the WLC group, the AE and TCC groups showed reductions in PMPU levels, physical and mental fatigue, but there was no difference between the two groups. Moreover, the effect of increasing self-esteem embodied in the TCC group was not present in the AE group. Compared to the WLC group, the relative abundance of Bacteroidaceae and Bacteroides were lower in the AE group, while the relative abundance of Erysipelotrichaceae and Alistipes were lower in the TCC group. And the relative abundance of Bacteroidaceae, Bacteroides, and Alistipes were significantly and negatively correlated with the decline in PMPU scores.
    Conclusion: AE or TCC is an effective, safe and efficient intervention for college students with PMPU, providing some physiological and psychological benefits and having some impact on their intestinal flora.
    MeSH term(s) Humans ; Tai Ji ; Cell Phone Use ; Gastrointestinal Microbiome ; Exercise ; Students/psychology
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 3148-3
    ISSN 1879-1379 ; 0022-3956
    ISSN (online) 1879-1379
    ISSN 0022-3956
    DOI 10.1016/j.jpsychires.2024.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Integrated Systems Pharmacology and Surface Plasmon Resonance Approaches to Reveal the Synergistic Effect of Multiple Components of Gu-Ben-Ke-Chuan Decoction on Chronic Bronchitis.

    Luo, Zhiqiang / Yu, Guohua / Wang, Wubin / Sun, Rui / Zhang, Binbin / Wang, Jing / Liu, Jing / Gao, Shan / Wang, Peng / Shi, Yuanyuan

    Journal of inflammation research

    2021  Volume 14, Page(s) 1455–1471

    Abstract: Introduction: Gu-Ben-Ke-Chuan (GBKC) decoction, a well-known prescription composed of seven herbs ...

    Abstract Introduction: Gu-Ben-Ke-Chuan (GBKC) decoction, a well-known prescription composed of seven herbs, has been widely used for treating chronic bronchitis (CB). However, the pharmacological constituents of GBKC and the underlying mechanisms by which these components act on CB remain unclear.
    Methods: Ultra-high-pressure liquid chromatography coupled with linear ion trap-Orbitrap tandem mass spectrometry (UHPLC-LTQ-Orbitrap) was first employed to rapidly identify compounds from GBKC. Thereafter, network pharmacology and molecular docking analyses were performed to identify the potential active constituents, candidate targets, and major pathways. Finally, the affinities between the key compounds and targets were verified via surface plasmon resonance (SPR) analysis. In addition, the anti-inflammatory effect of GBKC was verified using an LPS-induced inflammatory cell model based on the predicted results.
    Results: A total of 53 major compounds were identified in the GBKC decoction. After network pharmacology-based virtual screening, 141 major targets and 39 main compounds were identified to be effective in the treatment of CB. The major targets were highly enriched in the tumor necrosis factor (TNF) signaling pathway, suggesting that GBKC could attenuate the inflammatory response in patients with CB. Furthermore, molecular docking results indicated that 20 pairs of components and target proteins relevant to the TNF pathway exhibited notable interactions. Among them, eight compound-target pairs exhibited good affinity as per SPR analysis. In addition, the production of interleukin 6 and TNF-α in LPS-induced MH-S cells was suppressed after GBKC treatment.
    Conclusion: This study successfully clarified the mechanism of action of GBKC against CB, which demonstrated that the integrated strategy described above is reliable for identifying the active compounds and mechanisms responsible for the pharmacological activities of GBKC decoction.
    Language English
    Publishing date 2021-04-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494878-0
    ISSN 1178-7031
    ISSN 1178-7031
    DOI 10.2147/JIR.S303530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Tai Chi Chuan Exercise Improves Lung Function and Asthma Control through Immune Regulation in Childhood Asthma.

    Liao, Pei-Chun / Lin, Han-Hong / Chiang, Bor-Luen / Lee, Jyh-Hong / Yu, Hsin-Hui / Lin, Yu-Tsan / Yang, Yao-Hsu / Li, Pei-Yi / Wang, Li-Chieh / Sun, Wei-Zen

    Evidence-based complementary and alternative medicine : eCAM

    2019  Volume 2019, Page(s) 9146827

    Abstract: Background: Tai Chi Chuan (TCC) is an exercise of low to moderate intensity with key features ...

    Abstract Background: Tai Chi Chuan (TCC) is an exercise of low to moderate intensity with key features of mindfulness, structural alignment, and flexibility to relax the body and mind in adults. Our previous study showed that TCC could improve the quality of life (QoL), pulmonary function, and fractional exhaled nitric oxide in asthmatic children. We further investigated whether the benefits induced by TCC were associated with immune regulation.
    Method: Six- to twelve-year-old children diagnosed with mild to severe persistent asthma for at least one year according to the Global Initiative for Asthma guidelines were enrolled from a tertiary pediatric allergy center in Taiwan. Asthmatic children were divided into two groups based on their choice: (1) the TCC group had a 60-minute TCC exercise session once weekly led by an instructor and (2) the control group kept their original activity levels. All other exercises were encouraged as usual. Pulmonary function tests, laboratory tests, standardized pediatric asthma QoL questionnaire (PAQLQ(S)), and childhood asthma control test (C-ACT) were performed before and after the TCC program (12 weeks). Data on medications and exacerbations were collected from medical records.
    Results: There were no differences between the TCC (
    Conclusion: TCC exercise may improve pulmonary functions, asthma control, and QoL and prevent exacerbations in asthmatic children through immune regulation. Further research on detailed mechanisms is mandated.
    Language English
    Publishing date 2019-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2019/9146827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Soil Degassing From the Xianshuihe–Xiaojiang Fault System at the Eastern Boundary of the Chuan–Dian Rhombic Block, Southwest China

    Yutao Sun / Xiaocheng Zhou / Yucong Yan / Jingchao Li / Wenya Fang / Wanli Wang / Yongmei Liu

    Frontiers in Earth Science, Vol

    2021  Volume 9

    Abstract: The Chuan–Dian region, situated in the middle part of the north-south seismic zone of mainland ... were investigated in the Xianshuihe–Xiaojiang fault system (XXFS) at the eastern boundary of the Chuan ...

    Abstract The Chuan–Dian region, situated in the middle part of the north-south seismic zone of mainland China in a highly deformed area of the eastern margin of the Tibetan Plateau, is one of the principal areas for monitoring earthquake activities in China. In this study, the geochemical characteristics of soil degassing (of CH4, H2, CO2, Rn, and Hg) and, the relationship between degassing and fault activity, were investigated in the Xianshuihe–Xiaojiang fault system (XXFS) at the eastern boundary of the Chuan–Dian rhombic block. The mean soil-gas concentrations of CH4, H2, CO2, Rn, and Hg in the XXFS were 8.1 ppm, 9.9 ppm, 0.5%, 15.1 kBq/m3 and 12.9 ng/m3, respectively. The δ13CCO2 and δ13CCH4 values of the hot-spring gases varied from −11.9‰ to −3.7‰ and −62.5‰ to 17‰, respectively. The He-C isotopic ratios indicate that the carbon in the northern and middle parts of the XXFS may have originated from deep fluids, whereas the carbon in the southern part of the XXFS is of organic origin. The high concentrations of soil gas were distributed near the faults, indicating that the faults could act as channels for gas migration. The distributions of the high soil-gas concentrations in the XXFS coincide with the highest stress and maximum strain rates, indicating that the fault activity enhanced permeability and increased the emission rates of the gases. The results of this study will be helpful for degassing in active fault zones and earthquake monitoring.
    Keywords soil gas ; CO2 ; CH4 ; H2 ; Rn ; Hg ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways.

    Li, Qiuping / Wang, Guifang / Xiong, Shi Hang / Cao, Yuxue / Liu, Baojun / Sun, Jing / Li, Lulu / Mohammadtursun, Nabijan / Yu, Hua / Dong, Jingcheng / Wu, Jinfeng

    Journal of ethnopharmacology

    2020  Volume 261, Page(s) 113095

    Abstract: ... Fang-Chuan formula (BSFCF) is commonly used for the treatment of COPD in China. However, the mechanisms ...

    Abstract Ethnopharmacological relevance: Chronic obstructive pulmonary disease (COPD) is a respiratory inflammatory disease. Unlike asthma, COPD is insensitive to glucocorticoid treatment; thus, it is of great importance to find alternative medications, including Chinese medicine, to suppress inflammation. Bu-Shen-Fang-Chuan formula (BSFCF) is commonly used for the treatment of COPD in China. However, the mechanisms of BSFCF in COPD treatment are still unclear.
    Aim of the study: To verify the anti-inflammatory efficacy of BSFCF in COPD and to explore the possible mechanisms underlying its anti-inflammatory efficacy based on the phosphatidylinositol 3 kinase (PI3K)/protein kinase B (Akt)-Nuclear factor erythroid 2-related factor 2 (Nrf2) and Nuclear factor (NF)-κB signalling pathways.
    Materials and methods: A rat model of COPD was established by chronic exposure to cigarette smoke (CS) for 6 months. Bronchoalveolar lavage fluid (BALF) and blood were obtained to detect inflammatory cytokines. Lung samples were harvested, and part of each sample was fixed for subsequent H&E staining and immunohistochemical (IHC) analysis. The remaining lung tissues were used for RNA sequencing analysis and western blotting.
    Results: BSFCF significantly reduced inflammatory infiltration in the lungs of CS-exposed rats and decreased the concentrations of tumor necrosis factor (TNF)-α and interleukin (IL)-6 in both the BALF and serum. Additionally, BSFCF evidently attenuated NF-κB activation and downregulation of glucocorticoid receptor (GR) caused by CS. Furthermore, BSFCF increased the activation of PI3K/Akt-Nrf2 signalling in response to CS.
    Conclusions: BSFCF attenuated CS-induced inflammation in COPD, which was partially achieved through the PI3K/Akt-Nrf2 and NF-κB signalling pathways.
    MeSH term(s) Animals ; Anti-Inflammatory Agents/pharmacology ; Bronchoalveolar Lavage Fluid/chemistry ; Cigarette Smoking ; Cytokines/metabolism ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Lung/drug effects ; Lung/enzymology ; Lung/pathology ; Male ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinase ; Phosphorylation ; Pneumonia/enzymology ; Pneumonia/etiology ; Pneumonia/pathology ; Pneumonia/prevention & control ; Proto-Oncogene Proteins c-akt/metabolism ; Pulmonary Disease, Chronic Obstructive/enzymology ; Pulmonary Disease, Chronic Obstructive/etiology ; Pulmonary Disease, Chronic Obstructive/pathology ; Pulmonary Disease, Chronic Obstructive/prevention & control ; Rats, Sprague-Dawley ; Receptors, Glucocorticoid/metabolism ; Signal Transduction
    Chemical Substances Anti-Inflammatory Agents ; Bu-Shen-Fang-Chuan ; Cytokines ; Drugs, Chinese Herbal ; NF-E2-Related Factor 2 ; NF-kappa B ; Nfe2l2 protein, rat ; Receptors, Glucocorticoid ; Phosphatidylinositol 3-Kinase (EC 2.7.1.137) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2020-06-10
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2020.113095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Chemical constituents of Aconitum brachypodum from Dong-Chuan area].

    Wang, Hong-Yun / Zuo, Ai-Xue / Sun, Yun / Rao, Gao-Xiong

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2013  Volume 38, Issue 24, Page(s) 4324–4328

    Abstract: ... 80% ethanol extract of A. brachypodum collected from Dong-Chuan area was investigated, which led ...

    Abstract Aconitum brachypodum is traditionally known to be toxic chinese medicie, but its chemical constituents is not enough studied to date. To further elucidate the chemical constituents of A. brachypodum, 80% ethanol extract of A. brachypodum collected from Dong-Chuan area was investigated, which led to isolation of seventeen compounds. By spectroscopic methods, their structures were determined as hypaconitine (1), mesaconitine (2), talatisamine (3), neoline (4), fuziline (5), aconine (6), bullatine A (7), lepeine (8), songrine (9), isocorydine (10), beta-sitosterol (11), daucosterol (12), stearic acid (13), triacontanol (14), palmitic acid (15), benzoic acid (16), and inosine (17), respectively. All compounds except for compounds 1 and 7 were isolated from A. brachypodum for the first time.
    MeSH term(s) Aconitum/chemistry ; China ; Drugs, Chinese Herbal/chemistry ; Magnetic Resonance Spectroscopy
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2013-12
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effects of Tai Chi Chuan and Brisk Walking Exercise on Balance Ability in Elderly Women: A Randomized Controlled Trial.

    Sun, Wei / Ma, Xiujie / Wang, Lin / Zhang, Cui / Song, Qipeng / Gu, Houxin / Mao, Dewei

    Motor control

    2018  Volume 23, Issue 1, Page(s) 100–114

    Abstract: This study aims to investigate the effects of Tai Chi Chuan (TCC) and brisk walking (BW) on balance ...

    Abstract This study aims to investigate the effects of Tai Chi Chuan (TCC) and brisk walking (BW) on balance and training duration for the two exercises to significantly improve balance. A total of 48 elderly women were randomly divided into three groups. The TCC and BW groups completed a 60-min intervention training program with five sessions weekly for 16 weeks. Single-leg standing balance was tested every 4 weeks. Results showed that all the variables with eyes open improved on the eighth week (p < .05) in the TCC group and on the 12th week (p < .01) in the BW group. All variables with eyes closed improved on the 12th week (p < .01) in the TCC group and on the 16th week (p < .05) in the BW group. The results showed that 12 and 16 weeks of TCC and BW, respectively were essential to improve balance with eyes closed among the women aged 60-70 years.
    MeSH term(s) Aged ; Exercise/psychology ; Female ; Humans ; Male ; Postural Balance/physiology ; Tai Ji/methods ; Walking/physiology
    Language English
    Publishing date 2018-07-15
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1087-1640
    ISSN 1087-1640
    DOI 10.1123/mc.2017-0055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bu-Shen-Fang-Chuan formula attenuates T-lymphocytes recruitment in the lung of rats with COPD through suppressing CXCL9/CXCL10/CXCL11-CXCR3 axis.

    Li, Qiuping / Sun, Jing / Cao, Yuxue / Liu, Baojun / Li, Lulu / Mohammadtursun, Nabijan / Zhang, Hu / Dong, Jingcheng / Wu, Jinfeng

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2019  Volume 123, Page(s) 109735

    Abstract: ... function in COPD. Our multicenter clinical trial found that Bu-Shen-Fang-Chuan fomula (BSFCF), a Chinese ...

    Abstract Chronic obstructive pulmonary disease (COPD) is a common respiratory disease characterized by irreversible airflow limitation. The current medications show limited effects on the decline of pulmonary function in COPD. Our multicenter clinical trial found that Bu-Shen-Fang-Chuan fomula (BSFCF), a Chinese herbal formula, markedly reduced the frequencies of acute exacerbation of COPD and delayed lung function decline. However, the underlying mechanisms are still unclear. In this study, we established a COPD rat model through a 6-month exposure to cigarette smoke (CS) and found that BSFCF (7.2 g/kg) effectively improved CS-induced reduction in pulmonary function and remarkably decreased the numbers of inflammatory cells in bronchoalveolar lavage fluid (BALF). Importantly, BSFCF treatment notably prevented the accumulation of T-lymphocytes (especially CD8
    MeSH term(s) Animals ; Chemokine CXCL10/genetics ; Chemokine CXCL10/metabolism ; Chemokine CXCL11/genetics ; Chemokine CXCL11/metabolism ; Chemokine CXCL9/genetics ; Chemokine CXCL9/metabolism ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Regulation/drug effects ; Humans ; Lung/drug effects ; Lung/metabolism ; Lung/pathology ; Male ; Pulmonary Disease, Chronic Obstructive/chemically induced ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Random Allocation ; Rats ; Receptors, CXCR3/genetics ; Receptors, CXCR3/metabolism ; T-Lymphocytes/drug effects ; Transcriptome
    Chemical Substances Bu-Shen-Fang-Chuan ; CXCL9 protein, rat ; Chemokine CXCL10 ; Chemokine CXCL11 ; Chemokine CXCL9 ; Cxcl11 protein, rat ; Cxcr3 protein, rat ; Drugs, Chinese Herbal ; Receptors, CXCR3
    Language English
    Publishing date 2019-12-18
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2019.109735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tai Chi Chuan and Baduanjin practice modulates functional connectivity of the cognitive control network in older adults.

    Tao, Jing / Chen, Xiangli / Egorova, Natalia / Liu, Jiao / Xue, Xiehua / Wang, Qin / Zheng, Guohua / Li, Moyi / Hong, Wenjun / Sun, Sharon / Chen, Lidian / Kong, Jian

    Scientific reports

    2017  Volume 7, Page(s) 41581

    Abstract: ... we investigated whether Tai Chi Chuan and Baduanjin practice can modulate mental control functionand ... in the two exercise groups practiced either Tai Chi Chuan or Baduanjin for 12 weeks, and ... performed. We found that compared to the controls, 1) both Tai Chi Chuan and Baduanjin groups demonstrated ...

    Abstract Cognitive impairment is one of the most common problem saffecting older adults. In this study, we investigated whether Tai Chi Chuan and Baduanjin practice can modulate mental control functionand the resting state functional connectivity (rsFC) of the cognitive control network in older adults. Participants in the two exercise groups practiced either Tai Chi Chuan or Baduanjin for 12 weeks, and those in the control group received basic health education. Memory tests and fMRI scans were conducted at baseline and at the end of the study. Seed-based (bilateral dorsolateral prefrontal cortex, DLPFC) rsFC analysis was performed. We found that compared to the controls, 1) both Tai Chi Chuan and Baduanjin groups demonstrated significant improvements in mental control function; 2) the Tai Chi Chuan group showed a significant decrease in rsFC between the DLPFC and the left superior frontal gyrus (SFG) and anterior cingulate cortex; and 3) the Baduanjin group showed a significant decrease in rsFC between the DLPFC and the left putamen and insula. Mental control improvement was negatively associated with rsFC DLPFC-putamen changes across all subjects. These findings demonstrate the potential of Tai Chi Chuan and Baduanjin exercises in preventing cognitive decline.
    MeSH term(s) Age Factors ; Aged ; Brain/physiology ; Brain/physiopathology ; Brain Mapping ; Cognition ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neural Pathways ; Outcome Assessment, Health Care ; Tai Ji
    Language English
    Publishing date 2017-02-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep41581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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