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  1. Article ; Online: Understanding heterogeneity in mitochondrial injury after cardiac arrest using plasma metabolomics.

    Dezfulian, Cameron

    Resuscitation

    2022  Volume 179, Page(s) 83–85

    MeSH term(s) Heart Arrest/etiology ; Heart Arrest/therapy ; Humans ; Metabolomics ; Mitochondria
    Language English
    Publishing date 2022-08-06
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2022.08.001
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  2. Article ; Online: Recognizing the fastest growing cause of out-of-hospital cardiac arrest.

    Orkin, Aaron M / Dezfulian, Cameron

    Resuscitation

    2024  Volume 198, Page(s) 110206

    Language English
    Publishing date 2024-04-09
    Publishing country Ireland
    Document type Editorial
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2024.110206
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  3. Article: A New Perspective on Pulmonary Hypertension, Right Ventricular Failure, and Pediatric In-Hospital Cardiac Arrest.

    Dezfulian, Cameron

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2020  Volume 21, Issue 4, Page(s) 389–390

    MeSH term(s) Child ; Heart Arrest ; Heart Failure ; Humans ; Hypertension, Pulmonary ; Prevalence ; Ventricular Dysfunction, Right
    Language English
    Publishing date 2020-04-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000002216
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  4. Article: The clinical relevance of pediatric post-cardiac arrest myocardial dysfunction and hemodynamic instability.

    Dezfulian, Cameron

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2015  Volume 16, Issue 2, Page(s) 190–191

    MeSH term(s) Female ; Hospital Mortality ; Humans ; Male ; Out-of-Hospital Cardiac Arrest/mortality ; Vasoconstrictor Agents/therapeutic use ; Ventricular Function, Left
    Chemical Substances Vasoconstrictor Agents
    Language English
    Publishing date 2015-02
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000000332
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  5. Article ; Online: Precision Cardiac Arrest Resuscitation Based on Etiology.

    Dezfulian, Cameron / Lavonas, Eric J

    Critical care clinics

    2020  Volume 36, Issue 4, Page(s) 737–752

    Abstract: Cardiac arrest results from a broad range of etiologies that can be broadly grouped as sudden and asphyxial. Animal studies point to differences in injury pathways invoked in the heart and brain that drive injury and outcome after these different forms ... ...

    Abstract Cardiac arrest results from a broad range of etiologies that can be broadly grouped as sudden and asphyxial. Animal studies point to differences in injury pathways invoked in the heart and brain that drive injury and outcome after these different forms of cardiac arrest. Present guidelines largely ignore etiology in their management recommendations. Existing clinical data reveal significant heterogeneity in the utility of presently employed resuscitation and postresuscitation strategies based on etiology. The development of future neuroprotective and cardioprotective therapies should also take etiology into consideration to optimize the chances for successful translation.
    MeSH term(s) Animals ; Asphyxia ; Brain ; Cardiopulmonary Resuscitation ; Disease Models, Animal ; Heart ; Heart Arrest ; Humans ; Resuscitation
    Language English
    Publishing date 2020-08-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1006423-0
    ISSN 1557-8232 ; 0749-0704
    ISSN (online) 1557-8232
    ISSN 0749-0704
    DOI 10.1016/j.ccc.2020.07.005
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  6. Article ; Online: Impact of the Opioid Epidemic.

    Lavonas, Eric J / Dezfulian, Cameron

    Critical care clinics

    2020  Volume 36, Issue 4, Page(s) 753–769

    Abstract: In recent years the prescription opioid overdose epidemic has decreased, but has been more than offset by increases in overdose caused by fentanyl and fentanyl analogues. Opioid overdose patients should receive naloxone if they have significant ... ...

    Abstract In recent years the prescription opioid overdose epidemic has decreased, but has been more than offset by increases in overdose caused by fentanyl and fentanyl analogues. Opioid overdose patients should receive naloxone if they have significant respiratory depression and/or loss of protective airway reflexes. Patients who receive naloxone should be observed for recurrent opioid effects. Patients with opioid overdose may be admitted to the intensive care unit for naloxone infusions, treatment of noncardiogenic pulmonary edema, autonomic instability, or sequelae of hypoxia-ischemia or cardiac arrest. Primary and secondary prevention are important to reduce the number of people with life-threatening opioid overdose.
    MeSH term(s) Analgesics, Opioid/therapeutic use ; Drug Overdose ; Fentanyl/therapeutic use ; Humans ; Naloxone/therapeutic use ; Opioid Epidemic
    Chemical Substances Analgesics, Opioid ; Naloxone (36B82AMQ7N) ; Fentanyl (UF599785JZ)
    Language English
    Publishing date 2020-08-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1006423-0
    ISSN 1557-8232 ; 0749-0704
    ISSN (online) 1557-8232
    ISSN 0749-0704
    DOI 10.1016/j.ccc.2020.07.006
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  7. Article ; Online: The quest continues to identify coronary occlusion in OHCA without ST elevation.

    Coppler, Patrick J / Dezfulian, Cameron

    Resuscitation

    2019  Volume 146, Page(s) 258–260

    MeSH term(s) Comorbidity ; Coronary Angiography ; Coronary Occlusion ; Electrocardiography ; Humans ; ST Elevation Myocardial Infarction
    Language English
    Publishing date 2019-11-01
    Publishing country Ireland
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2019.10.024
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  8. Article ; Online: Metformin protects against cardiac and renal damage in diabetic cardiac arrest patients.

    Rutledge, Cody A / Kaufman, Brett A / Dezfulian, Cameron / Elmer, Jonathan

    Resuscitation

    2022  Volume 174, Page(s) 42–46

    Abstract: Introduction: Metformin is a first-line diabetic therapy that improves survival in a wide number of ischemic pathologies. We tested the association of metformin with markers of cardiac and renal injury in diabetic post-arrest patients.: Methods: We ... ...

    Abstract Introduction: Metformin is a first-line diabetic therapy that improves survival in a wide number of ischemic pathologies. We tested the association of metformin with markers of cardiac and renal injury in diabetic post-arrest patients.
    Methods: We performed a retrospective analysis of clinical outcomes in diabetic cardiac arrest patients with and without metformin therapy at a single academic medical center. We used generalized linear models to test the independent association of metformin, insulin, and other hypoglycemic agents with peak 24-hour serum creatinine and peak 24-hour serum troponin.
    Results: Metformin prescription at the time of SCA was independently associated with lower 24-hour peak serum troponin and lower 24-hour peak serum creatinine when compared to non-metformin patients.
    Conclusion: Metformin pretreatment may offer cardiac and renal protection for diabetic patients during sudden cardiac arrest.
    MeSH term(s) Creatinine ; Diabetes Mellitus/drug therapy ; Heart Arrest/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Kidney ; Metformin/therapeutic use ; Retrospective Studies ; Troponin
    Chemical Substances Hypoglycemic Agents ; Troponin ; Metformin (9100L32L2N) ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2022-03-21
    Publishing country Ireland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2022.03.017
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  9. Article ; Online: The elusive goal carbon dioxide target after cardiac arrest.

    Hirzallah, Mohammad I / Dezfulian, Cameron

    Resuscitation

    2018  Volume 135, Page(s) 226–227

    MeSH term(s) Carbon Dioxide ; Cohort Studies ; Goals ; Heart Arrest ; Humans ; Partial Pressure ; Prospective Studies
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2018-12-15
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2018.11.019
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  10. Article: The authors reply.

    Kaselitz, Timothy B / Dezfulian, Cameron / Remy, Kenneth E

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2020  Volume 21, Issue 10, Page(s) 930–931

    MeSH term(s) Betacoronavirus ; COVID-19 ; Child ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000002517
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