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  1. Article: Risk Factors for Death in Patients with Severe Acute Pancreatitis in Guizhou Province, China.

    Li, Jun / Gao, Jingyan / Huang, Min / Fu, Xiaoyun / Fu, Bao

    Gastroenterology research and practice

    2024  Volume 2024, Page(s) 8236616

    Abstract: Aim: To compare the clinical characteristics of survival and nonsurvival patients with severe acute pancreatitis (SAP) and explore the risk of mortality in SAP patients.: Methods: This was a single-center retrospective study performed in a severe ... ...

    Abstract Aim: To compare the clinical characteristics of survival and nonsurvival patients with severe acute pancreatitis (SAP) and explore the risk of mortality in SAP patients.
    Methods: This was a single-center retrospective study performed in a severe acute pancreatitis diagnosis and treatment center. According to the outcome, SAP patients were divided into survival group and nonsurvival group. One-way ANOVA or independent
    Results: A total of 486 SAP patients were included in the study, and the 90-day mortality for SAP patients was 13.58%. The common etiologies of SAP are biliary tract diseases (69.75%) and hyperlipidemia (17.28%). The most common complications caused by SAP were organ failure (55.14%), ARDS (50.62%), AKI (30.45%), sepsis (27.16%), and abdominal fluid collection (27.57%). There were differences in age, complications, and medical intervention between the nonsurvival group and the survival group. The main causes of death were infection (46.97%), abdominal bleeding (28.79%), and organ failure (9.09%). The binary logistic regression analysis showed that there were significant differences in age, AKI, sepsis, abdominal hemorrhage, organ failure, laparotomy, creatinine, and APTT between the nonsurvival group and the survival group.
    Conclusion: Age, AKI, sepsis, abdominal hemorrhage, and organ failure are risk factors for mortality in SAP patients. SAP patients with high creatinine and prolonged APTT upon admission require doctors to be vigilant. The main cause of death in SAP patients is pancreatitis-related organ failure and secondary infection.
    Language English
    Publishing date 2024-04-01
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2435460-0
    ISSN 1687-630X ; 1687-6121
    ISSN (online) 1687-630X
    ISSN 1687-6121
    DOI 10.1155/2024/8236616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Bayesian joint model for compositional mediation effect selection in microbiome data.

    Fu, Jingyan / Koslovsky, Matthew D / Neophytou, Andreas M / Vannucci, Marina

    Statistics in medicine

    2023  Volume 42, Issue 17, Page(s) 2999–3015

    Abstract: Analyzing multivariate count data generated by high-throughput sequencing technology in microbiome research studies is challenging due to the high-dimensional and compositional structure of the data and overdispersion. In practice, researchers are often ... ...

    Abstract Analyzing multivariate count data generated by high-throughput sequencing technology in microbiome research studies is challenging due to the high-dimensional and compositional structure of the data and overdispersion. In practice, researchers are often interested in investigating how the microbiome may mediate the relation between an assigned treatment and an observed phenotypic response. Existing approaches designed for compositional mediation analysis are unable to simultaneously determine the presence of direct effects, relative indirect effects, and overall indirect effects, while quantifying their uncertainty. We propose a formulation of a Bayesian joint model for compositional data that allows for the identification, estimation, and uncertainty quantification of various causal estimands in high-dimensional mediation analysis. We conduct simulation studies and compare our method's mediation effects selection performance with existing methods. Finally, we apply our method to a benchmark data set investigating the sub-therapeutic antibiotic treatment effect on body weight in early-life mice.
    MeSH term(s) Animals ; Mice ; Models, Statistical ; Bayes Theorem ; Computer Simulation ; Microbiota ; Causality
    Language English
    Publishing date 2023-05-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.9764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1756: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Low CO

    Liu, Sha / Tang, Lin / Fu, Jingyan / Zhao, Caixia / Zhang, Ying / Yin, Meng / Wang, Maolin / Wang, Rui / Zhao, Yun

    Biotechnology for biofuels and bioproducts

    2024  Volume 17, Issue 1, Page(s) 28

    Abstract: Background: Photosynthesis is a fundamental process that underlies the formation of crop yield, wherein light serves as the driving force and carbon dioxide (CO: Results: In the rapeseed experimental fields located on the plateau (Lhasa, Tibet), we ... ...

    Abstract Background: Photosynthesis is a fundamental process that underlies the formation of crop yield, wherein light serves as the driving force and carbon dioxide (CO
    Results: In the rapeseed experimental fields located on the plateau (Lhasa, Tibet), we measured abundant sunlight, characterized by an average daily photosynthetically active radiation (PAR) of 1413 μmol m
    Conclusions: This study established a screening strategy for plateau high-yielding rapeseed materials, obtained six varieties which were suitable for plateau cultivation, explored the mechanism of rapeseed response to the plateau environment, and thus provides a feasible strategy for plateau-adapted rapeseed breeding.
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ISSN 2731-3654
    ISSN (online) 2731-3654
    DOI 10.1186/s13068-024-02481-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Nine-fold symmetry of centriole: The joint efforts of its core proteins.

    Tian, Yuan / Yan, Yuxuan / Fu, Jingyan

    BioEssays : news and reviews in molecular, cellular and developmental biology

    2022  Volume 44, Issue 3, Page(s) e2100262

    Abstract: The centriole is a widely conserved organelle required for the assembly of centrosomes, cilia, and flagella. Its striking feature - the nine-fold symmetrical structure, was discovered over 70 years ago by transmission electron microscopy, and since ... ...

    Abstract The centriole is a widely conserved organelle required for the assembly of centrosomes, cilia, and flagella. Its striking feature - the nine-fold symmetrical structure, was discovered over 70 years ago by transmission electron microscopy, and since elaborated mostly by cryo-electron microscopy and super-resolution microscopy. Here, we review the discoveries that led to the current understanding of how the nine-fold symmetrical structure is built. We focus on the recent findings of the centriole structure in high resolution, its assembly pathways, and its nine-fold distributed components. We propose a model that the assembly of the nine-fold symmetrical centriole depends on the concerted efforts of its core proteins. Also see the video abstract here: https://youtu.be/m4h_3II_WJo.
    MeSH term(s) Centrioles/metabolism ; Centrosome ; Cilia/metabolism ; Cryoelectron Microscopy ; Organelles
    Language English
    Publishing date 2022-01-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Video-Audio Media
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202100262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2024: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Dielectric Tetramer Nanoresonators Supporting Strong Superchiral Fields for Vibrational Circular Dichroism Spectroscopy.

    Ye, Longfang / Li, Jingyan / Richter, Felix Ulrich / Jahani, Yasaman / Lu, Rui / Lee, Bo Ray / Tseng, Ming Lun / Altug, Hatice

    ACS photonics

    2023  Volume 10, Issue 12, Page(s) 4377–4384

    Abstract: Chirality ( ...

    Abstract Chirality (
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ISSN 2330-4022
    ISSN 2330-4022
    DOI 10.1021/acsphotonics.3c01186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Phase separation in innate immune response and inflammation-related diseases.

    Ma, Huihui / Liu, Mingxi / Fu, Rao / Feng, Jia / Ren, Haoran / Cao, Jingyan / Shi, Ming

    Frontiers in immunology

    2023  Volume 14, Page(s) 1086192

    Abstract: Inflammation induced by nonspecific pathogenic or endogenous danger signals is an essential mechanism of innate immune response. The innate immune responses are rapidly triggered by conserved germline-encoded receptors that recognize broad patterns ... ...

    Abstract Inflammation induced by nonspecific pathogenic or endogenous danger signals is an essential mechanism of innate immune response. The innate immune responses are rapidly triggered by conserved germline-encoded receptors that recognize broad patterns indicative of danger, with subsequent signal amplification by modular effectors, which have been the subject of intense investigation for many years. Until recently, however, the critical role of intrinsic disorder-driven phase separation in facilitating innate immune responses went largely unappreciated. In this review, we discuss emerging evidences that many innate immune receptors, effectors, and/or interactors function as "all-or-nothing" switch-like hubs to stimulate acute and chronic inflammation. By concentrating or relegating modular signaling components to phase-separated compartments, cells construct flexible and spatiotemporal distributions of key signaling events to ensure rapid and effective immune responses to a myriad of potentially harmful stimuli.
    MeSH term(s) Humans ; Immunity, Innate ; Inflammation ; Germ Cells ; Signal Transduction
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1086192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Li metal anode interface in sulfide‐based all‐solid‐state Li batteries

    Jingyan Li / Jiayao Luo / Xiang Li / Yongzhu Fu / Jinhui Zhu / Xiaodong Zhuang

    EcoMat, Vol 5, Iss 8, Pp n/a-n/a (2023)

    2023  

    Abstract: Abstract Sulfide solid electrolyte (SSE)‐based all‐solid‐state Li batteries (ASSLBs) can overcome the problems of low energy density and safety concern of current Li‐ion batteries. However, the practical application of SSE‐based ASSLBs is suffered from ... ...

    Abstract Abstract Sulfide solid electrolyte (SSE)‐based all‐solid‐state Li batteries (ASSLBs) can overcome the problems of low energy density and safety concern of current Li‐ion batteries. However, the practical application of SSE‐based ASSLBs is suffered from several problems, especially interfacial issues between Li metal anode (LMA) and SSEs. Therefore, in this study, the problems of the LMA–SSE interface and their corresponding solutions are reviewed. First, the interfacial problems are summarized, namely the side reactions of SSEs, the Li dendrite growth, and poor contact between the electrode and electrolyte. Second, the available strategies to improve the robustness of the interface are discussed, including the protection of the LMA, substitution of the LMA, and modification of SSEs. Third, the characterization methods used to analyze the morphological and compositional evolution of the interface during cycling are introduced. Finally, the limitations and future research directions are proposed.
    Keywords all‐solid‐state Li batteries ; interface ; Li metal anode ; sulfide solid electrolytes ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 600
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Nine‐fold symmetry of centriole: The joint efforts of its core proteins

    Tian, Yuan / Yan, Yuxuan / Fu, Jingyan

    BioEssays. 2022 Mar., v. 44, no. 3

    2022  

    Abstract: The centriole is a widely conserved organelle required for the assembly of centrosomes, cilia, and flagella. Its striking feature – the nine‐fold symmetrical structure, was discovered over 70 years ago by transmission electron microscopy, and since ... ...

    Abstract The centriole is a widely conserved organelle required for the assembly of centrosomes, cilia, and flagella. Its striking feature – the nine‐fold symmetrical structure, was discovered over 70 years ago by transmission electron microscopy, and since elaborated mostly by cryo‐electron microscopy and super‐resolution microscopy. Here, we review the discoveries that led to the current understanding of how the nine‐fold symmetrical structure is built. We focus on the recent findings of the centriole structure in high resolution, its assembly pathways, and its nine‐fold distributed components. We propose a model that the assembly of the nine‐fold symmetrical centriole depends on the concerted efforts of its core proteins. Also see the video abstract here: https://youtu.be/m4h_3II_WJo
    Keywords centrioles ; cryo-electron microscopy ; flagellum ; models ; transmission electron microscopy
    Language English
    Dates of publication 2022-03
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note REVIEW
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202100262
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 2009/501: Show issues

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  9. Article ; Online: Research and Practice of Comprehensive Utilization Technology of Mine Water Based on Green Mining

    Wang Li / Fu Yongzhi / Zhu Jingyan

    E3S Web of Conferences, Vol 245, p

    2021  Volume 01007

    Abstract: Yannan Coal Mine in Dayan Mining Area creatively utilizes water-preserving mining technology to block abandoned roadways to build underground reservoirs and build underground sedimentation tanks. It implements a zoned utilization and zoned management ... ...

    Abstract Yannan Coal Mine in Dayan Mining Area creatively utilizes water-preserving mining technology to block abandoned roadways to build underground reservoirs and build underground sedimentation tanks. It implements a zoned utilization and zoned management optimization technical plan for mine water, so that it can meet the needs of underground working face production and surface production and domestic water use. This mine water comprehensively recycles water conservation mining technology and makes full use of mine water resources. This greatly improves the utilization rate of mine water, realizes the recycling of mine water, and accelerates the construction of green mines.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: The epidemiology and clinical features of pediatric acute pancreatitis in north of Guizhou, China.

    Bo, Shixing / Gao, Jingyan / Zhou, Yanna / Wang, Chaohui / Liang, Wenmei / Fu, Xiaoyun

    Journal of public health research

    2023  Volume 12, Issue 4, Page(s) 22799036231204322

    Abstract: Background: The epidemiological data on distribution of pediatric acute pancreatitis was deficiency. And the purpose of this research was to investigate the epidemiology and clinical features of pediatric acute pancreatitis in the population in north of ...

    Abstract Background: The epidemiological data on distribution of pediatric acute pancreatitis was deficiency. And the purpose of this research was to investigate the epidemiology and clinical features of pediatric acute pancreatitis in the population in north of Guizhou, China.
    Design and methods: A retrospective case analysis was conducted to accomplish the aim. Patients who were under 18 years old with acute pancreatitis were recruited. Data were collected directly from Hospital Information System (HIS) after patients were discharged from the hospital.
    Results: A total of 95 children aged from 3 to 17 years were collected, 49 patients were boys and 46 were girls. In addition, the percentage of acute pancreatitis occurring in girls aged 15-17 years was significantly higher than that of boys (54.3% vs 36.7%). Meanwhile, the percentage of severe patients over 12 years exceeded 90.0%. Moreover, the proportion of severe acute pancreatitis in girls was significantly higher than that in boys (26.1% vs 10.2%), and 64.7% of severe patients were from 12 to 14. What's more, more patients occurred in May, June, and December and on weekends, 47.1% (8/17) severe cases occurred in May, June, and July, and 47.1% (8/17) severe patients occurred on weekend. The length of hospitalization and hospitalization costs of severe patients were found higher compared to mild patients.
    Conclusions: Higher risk of pediatric acute pancreatitis, especially severe acute pancreatitis, in north of Guizhou, China occurred on weekend, during May and June, and among children aged 12-17 years, especially girls. Additionally, severe acute pancreatitis was associated with higher hospitalization costs and longer hospitalization length.
    Language English
    Publishing date 2023-10-08
    Publishing country United States
    Document type Journal Article
    ISSN 2279-9028
    ISSN 2279-9028
    DOI 10.1177/22799036231204322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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