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  1. Article ; Online: Integrated network pharmacology and experimental verification to explore the potential mechanism of San Ying decoction for treating triple-negative breast cancer.

    Yang, Xiaojuan / Li, Feifei / Shi, Youyang / Wu, Yuanyuan / Yang, Rui / Liu, Xiaofei / Zhang, Yang / Zhang, Guangtao / Ma, Mei / Luo, Zhanyang / Han, Xianghui / Xie, Ying / Liu, Sheng

    Acta biochimica et biophysica Sinica

    2024  

    Abstract: Traditional Chinese medicine (TCM) has been used to treat triple-negative breast cancer (TNBC), a breast cancer subtype with poor prognosis. Clinical studies have verified that the Sanyingfang formula (SYF), a TCM prescription, has obvious effects on ... ...

    Abstract Traditional Chinese medicine (TCM) has been used to treat triple-negative breast cancer (TNBC), a breast cancer subtype with poor prognosis. Clinical studies have verified that the Sanyingfang formula (SYF), a TCM prescription, has obvious effects on inhibiting breast cancer recurrence and metastasis, prolonging patient survival, and reducing clinical symptoms. However, its active ingredients and molecular mechanisms are still unclear. In this study, the active ingredients of each herbal medicine composing SYF and their target proteins are obtained from the Traditional Chinese Medicine Systems Pharmacology database. Breast cancer-related genes are obtained from the GeneCards database. Major targets and pathways related to SYF treatment in breast cancer are identified by analyzing the above data. By conducting molecular docking analysis, we find that the active ingredients quercetin and luteolin bind well to the key targets KDR1, PPARG, SOD1, and VCAM1.
    Language English
    Publishing date 2024-03-21
    Publishing country China
    Document type Journal Article
    ZDB-ID 2175256-4
    ISSN 1745-7270 ; 0582-9879 ; 1672-9145
    ISSN (online) 1745-7270
    ISSN 0582-9879 ; 1672-9145
    DOI 10.3724/abbs.2024015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dialogue with Hou Ying

    Aimee T. Liu / Hou Ying / Amanda Liu

    Creative Arts in Education and Therapy, Vol 6, Iss 1, Pp 50-

    A Dance Artist’s Reflections on the Crisis of Human Civilization

    2020  Volume 60

    Abstract: ... with Hou Ying and Aimee T. Liu, Hou shared her inspiration for creating the work “Immanent Fall”, and ... In March 2019, Hou Ying presented a site-specific dance performance called “Immanent fall” as part ...

    Abstract In March 2019, Hou Ying presented a site-specific dance performance called “Immanent fall” as part of the “Civilization: The Way We Live Now” series to an audience in the labyrinth-like exhibition hall in the Center for Contemporary Art in Beijing. Her creation seems to have had an amazing predictive function which was almost identical to what is happening in the world today, the outbreak of COVID-19. In an in-depth interview with Hou Ying and Aimee T. Liu, Hou shared her inspiration for creating the work “Immanent Fall”, and explored her reflections on the crisis that hit human civilization on 23 February, 2020.
    Keywords covid-19 ; crisis ; dance ; hou ying ; human civilization ; Visual arts ; N1-9211 ; Special aspects of education ; LC8-6691 ; covid19
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Inspirees International B.V.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article ; Online: The Effects of Ying Yang Bao on Nutritional Status of Children Aged 6-60 Months in Underdeveloped Rural Areas of China.

    Feng, Jing / Wang, Yongjun / Liu, Tingting / Huo, Junsheng / Zhuo, Qin / Gong, Zhaolong

    Nutrients

    2024  Volume 16, Issue 2

    Abstract: The Ying Yang Bao (YYB) intervention, a national policy in China, has been implemented for over two ...

    Abstract The Ying Yang Bao (YYB) intervention, a national policy in China, has been implemented for over two decades. Most previous studies have focused only on the short-term effects of YYB, while the long-term effects remain unexplored. This study was designed to evaluate the long-term effects of YYB in children aged 6-60 months. A sample of 4666 children was divided into intervention and control groups. Information on basic characteristics, physical examination, YYB consumption, etc., was obtained annually from 2018 to 2021. T-tests or chi-square tests were used to compare differences between the groups for continuous or categorical variables. Children in the intervention group showed greater incremental improvements in hemoglobin levels and physical development (
    MeSH term(s) Humans ; Anemia/epidemiology ; Cachexia ; China/epidemiology ; Growth Disorders ; Nutritional Status ; Infant ; Child, Preschool
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16020202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [An interview with YU Ying-ao-a scholar in clinical literature].

    Liu, X C

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2021  Volume 51, Issue 4, Page(s) 235–243

    Abstract: Professor Ying-ao YU came from a family with medical background and studied under the guidance ...

    Abstract Professor Ying-ao YU came from a family with medical background and studied under the guidance of Bo-wei QIN. He graduated from Shanghai Second Medical College. He also was a graduate of the first session of the Integrated Medicine in China. After that, he was assigned to the editorial office of the Academy of Chinese Medicine, engaging in the study of clinical literature of traditional Chinese medicine(TCM). With National Medical Master Zhi-zheng LU, he went to Baotou Steel Staff Hospital in Inner Mongolia to implement TCM training. He has devoted himself to research of TCM clinical literature and his clinical practice for more than 60 years. Based on this work, he developed his own clinical diagnosis and treatment model entitled Differentiation of Diseases, Differentiation of Symptoms and Signs-General Therapy-Treatment through Prescription-Treatment through Clinical Symptoms and Signs. This model makes an outstanding contribution to clinical TCM and clinical literature research. The author interviewed Professor YU systematically in terms of his experiences in TCM clinically and his cultural heritage in TCM clinical philology to share with readers.
    MeSH term(s) Academies and Institutes ; China ; History, 20th Century ; Humans ; Medicine, Chinese Traditional ; Prescriptions ; Universities
    Language Chinese
    Publishing date 2021-10-13
    Publishing country China
    Document type Biography ; Historical Article ; Interview
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    DOI 10.3760/cma.j.cn112155-20201119-00179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4688: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification lotion with soaking agent in the treatment of diabetic foot ulcers

    YingRui, Wang / Zheng, Liu / GuoYan, Liu / Hongjie, Wang / YuLian, Liu / BoWen, Wang

    Pharmacological research. 2022,

    2022  

    Abstract: Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification ... the active ingredients of the drug in the Gong Ying detoxification lotion, and used the UniProt database to obtain ... enrichment, and finally Cytoscape software used to construct the " Gong Ying detoxification lotion component ...

    Abstract Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification lotion with soaking agent in the treatment of diabetic foot ulcers. We used the traditional Chinese medicine system pharmacology analysis platform (Tcmsp) and the BATMAN-TCM database to retrieve the active ingredients of the drug in the Gong Ying detoxification lotion, and used the UniProt database to obtain the predicted target and to explore the potential targets of the Diabetic foot ulcers; the String platform was used to construct the protein interaction Action network; the data were analyzed by GO and KEGG pathway enrichment, and finally Cytoscape software used to construct the " Gong Ying detoxification lotion component-Diabetic foot ulcers target-pathway" network. The core active ingredients of Gong Ying detoxification lotion in the treatment of Diabetic foot ulcers were found to be quercetin, choline, wogonin. The biological pathways mainly involved involve classical pathways operating in cancer including the HIF-1 signaling pathway. This study in reveals the characteristics of multi-target and multi-path combination of Gong Ying to treat Diabetic foot ulcers, and provides research ideas and theoretical basis for further treatment of Diabetic foot ulcers.
    Keywords Oriental traditional medicine ; choline ; computer software ; databases ; diabetic foot ; drugs ; pharmacology ; quercetin ; research
    Language English
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ISSN 2667-1425
    DOI 10.1016/j.prmcm.2022.100084
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification lotion with soaking agent in the treatment of diabetic foot ulcers

    Wang YingRui / Liu Zheng / Liu GuoYan / Wang Hongjie / Liu YuLian / Wang BoWen

    Pharmacological Research - Modern Chinese Medicine, Vol 3, Iss , Pp 100084- (2022)

    2022  

    Abstract: Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification ... the active ingredients of the drug in the Gong Ying detoxification lotion, and used the UniProt database to obtain ... enrichment, and finally Cytoscape software used to construct the '' Gong Ying detoxification lotion component ...

    Abstract Network-based pharmacological analysis of the molecular mechanism of Gong Ying detoxification lotion with soaking agent in the treatment of diabetic foot ulcers. We used the traditional Chinese medicine system pharmacology analysis platform (Tcmsp) and the BATMAN-TCM database to retrieve the active ingredients of the drug in the Gong Ying detoxification lotion, and used the UniProt database to obtain the predicted target and to explore the potential targets of the Diabetic foot ulcers; the String platform was used to construct the protein interaction Action network; the data were analyzed by GO and KEGG pathway enrichment, and finally Cytoscape software used to construct the '' Gong Ying detoxification lotion component-Diabetic foot ulcers target-pathway'' network. The core active ingredients of Gong Ying detoxification lotion in the treatment of Diabetic foot ulcers were found to be quercetin, choline, wogonin. The biological pathways mainly involved involve classical pathways operating in cancer including the HIF-1 signaling pathway. This study in reveals the characteristics of multi-target and multi-path combination of Gong Ying to treat Diabetic foot ulcers, and provides research ideas and theoretical basis for further treatment of Diabetic foot ulcers.
    Keywords Public antidote wasolytic wash ; Network pharmacology ; Diabetic foot ulcers ; Molecular mechanism ; External treatment of traditional chinese medicine ; Other systems of medicine ; RZ201-999 ; Therapeutics. Pharmacology ; RM1-950
    Subject code 004
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Effects of the Duration of Ying Yang Bao Consumption on Hemoglobin Concentration in Infants and Young Children in Less Developed Areas of China.

    Feng, Jing / Wang, Yongjun / Liu, Tingting / Huo, Junsheng / Zhuo, Qin / Gong, Zhaolong

    Nutrients

    2022  Volume 14, Issue 21

    Abstract: Ying Yang Bao (YYB) is conventionally prescribed as a nutritional supplement to infants and ...

    Abstract Ying Yang Bao (YYB) is conventionally prescribed as a nutritional supplement to infants and young children (IYC) in less developed areas of China. However, whether 18-month YYB consumption is reasonable needs assessment. This study examined the influence of the duration of YYB consumption on hemoglobin (Hb) levels and anemia prevalence. Data from the Nutrition Improvement Project on Children in Poor Areas of China in 2018-2019 were used. Questionnaires were used to collect information on basic characteristics, dietary status, and YYB consumption. Propensity score matching (PSM) was used to balance confounders. Hb levels and anemia prevalence in IYC with different durations of YYB consumption were compared. After PSM, all covariates were well-balanced, and 1151 pairs of IYC were included in subsequent analyses. During the 1st-9th months of intervention, YYB effectively increased Hb levels and reduced anemia prevalence in the intervention group. During the 10th-18th months of intervention, Hb levels in the control group increased and anemia prevalence decreased, while Hb levels and anemia prevalence fluctuated in the intervention group. In conclusion, YYB was effective in improving nutritional status of infants, but had a limited effect in young children. Nutritional supplements with different quantities or nutrients should be considered for young children.
    MeSH term(s) Infant ; Child ; Humans ; Child, Preschool ; Rural Population ; China/epidemiology ; Anemia/epidemiology ; Anemia/prevention & control ; Dietary Supplements ; Prevalence ; Hemoglobins/analysis
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2022-10-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14214539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Cost-benefit analysis of Ying Yang Bao (YYB) intervention in 6 to 23 months rural infants].

    Huang, Conghui / Wei, Yanli / Huo, Junsheng / Liu, Kejun / Sun, Jing / Huang, Jian / Gong, Weiyi / Wang, Ou

    Wei sheng yan jiu = Journal of hygiene research

    2022  Volume 51, Issue 3, Page(s) 432–436

    Abstract: Objective: To study on the cost-benefit from anemia and stunting reduction of Ying Yang Bao(YYB ...

    Abstract Objective: To study on the cost-benefit from anemia and stunting reduction of Ying Yang Bao(YYB) intervention in 6 to 23 months rural infants in the six counties of Shanxi, Hubei and Yunnan provinces.
    Methods: YYB was distributed to 6-23 months infants in 6 counties by YYB nutrition intervention project. The numbers of childhood recovered from stunting and anemia was collected by a designed project monitoring plan. The cost-benefit was analyzed with PROFILING model as a nutritional microeconomic tool.
    Results: Total numbers of monitored infants was 10 672 while the total cost of YYB intervention was estimated 2.57 million RMB. From 2012 to 2020, the total benefit was 14.92 million RMB from recover of stunting and anemia by YYB project and the average cost-benefit ratio of 6 counties was 1∶5.8. Sensitivity analysis showed the result of this study was stable.
    Conclusion: The YYB nutrition intervention for infants aged 6-23 months in the six counties of Shanxi, Hubei and Yunnan provinces showed a high cost-benefit ratio.
    MeSH term(s) Anemia ; China ; Cost-Benefit Analysis ; Dietary Supplements ; Growth Disorders ; Humans ; Infant
    Language Chinese
    Publishing date 2022-06-20
    Publishing country China
    Document type Journal Article
    ZDB-ID 1050909-4
    ISSN 1000-8020
    ISSN 1000-8020
    DOI 10.19813/j.cnki.weishengyanjiu.2022.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4878: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article: Post-treatment With Qing-Ying-Tang, a Compound Chinese Medicine Relives Lipopolysaccharide-Induced Cerebral Microcirculation Disturbance in Mice.

    Wang, Hao-Min / Huang, Ping / Li, Quan / Yan, Lu-Lu / Sun, Kai / Yan, Li / Pan, Chun-Shui / Wei, Xiao-Hong / Liu, Yu-Ying / Hu, Bai-He / Wang, Chuan-She / Fan, Jing-Yu / Han, Jing-Yan

    Frontiers in physiology

    2019  Volume 10, Page(s) 1320

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2019-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2019.01320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The complete chloroplast genome of Sinopodophyllum hexandrum Ying (Berberidaceae).

    Meng, Lihua / Liu, Ruijuan / Chen, Jianbing / Ding, Chenxu

    Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis

    2017  Volume 28, Issue 3, Page(s) 342–343

    Abstract: The complete nucleotide sequence of the Sinopodophyllum hexandrum Ying chloroplast genome (cpDNA ...

    Abstract The complete nucleotide sequence of the Sinopodophyllum hexandrum Ying chloroplast genome (cpDNA) was determined based on next-generation sequencing technologies in this study. The genome was 157 203 bp in length, containing a pair of inverted repeat (IRa and IRb) regions of 25 960 bp, which were separated by a large single-copy (LSC) region of 87 065 bp and a small single-copy (SSC) region of 18 218 bp, respectively. The cpDNA contained 148 genes, including 96 protein-coding genes, 8 ribosomal RNA genes, and 44 tRNA genes. In these genes, eight harbored a single intron, and two (ycf3 and clpP) contained a couple of introns. The cpDNA AT content of S. hexandrum cpDNA is 61.5%.
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article
    ISSN 2470-1408
    ISSN (online) 2470-1408
    DOI 10.3109/19401736.2015.1122773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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