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Article ; Online: Diagnosis and Management of Perinatal Depression.

Rossi, Nicole Marie / Radney, Lauren

2022 Volume 26, Issue 4, Page(s) 318–330

Abstract: Perinatal depression is a mood disorder that may occur during pregnancy or within a year after childbirth. It can be disabling for the birthing parent and cause attachment and developmental problems for the infant. A host of risk factors, including ... ...

Abstract	Perinatal depression is a mood disorder that may occur during pregnancy or within a year after childbirth. It can be disabling for the birthing parent and cause attachment and developmental problems for the infant. A host of risk factors, including genetics, reproductive history, and life experiences, are associated with perinatal depression. With validated screening tools, health care providers can assess individuals, initiate treatment, and/or refer as appropriate. Successful treatment, which may include modalities such as cognitive behavioral therapy and/or pharmacologic therapies, helps individuals maintain a sense of control, develop self-confidence, take control of their thinking, and learn coping skills. Integrative therapies and lifestyle changes have some success but may not be adequate for many individuals. Patients may benefit from providers learning and initiating cognitive behavioral therapy techniques while awaiting therapy.
MeSH term(s)	Depression/diagnosis ; Depression/therapy ; Depression, Postpartum/prevention & control ; Depression, Postpartum/therapy ; Female ; Humans ; Infant ; Mass Screening/methods ; Mood Disorders ; Pregnancy ; Risk Factors
Language	English
Publishing date	2022-06-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2275619-X
ISSN	1751-486X ; 1751-4851
ISSN (online)	1751-486X
ISSN	1751-4851
DOI	10.1016/j.nwh.2022.05.007
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Zs.A 4732: Show issues

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Article ; Online: Drug-Induced sleep endoscopy in children: NAVOTEL scoring system development.

Qarbal, Jawad / Le Treut-Gay, Claire / Allali, Laure / Rossi, Marie-Eva / Nicollas, Richard / Moreddu, Eric

Pediatric pulmonology

2023 Volume 58, Issue 7, Page(s) 1889–1895

Abstract: ... frequent obstructive site (63% of patients), and the nasal cavities (N) and the larynx (L) were ...

Abstract	Objectives: Pediatric drug-induced sleep endoscopy (DISE) lacks a universal and easy-to-use scoring system. The velum, oropharynx, tongue, epiglottis (VOTE) scoring system is widely used but needs to be completed in pediatrics. The main objective of this study was to investigate the distribution of obstructive sites in DISE and to propose an appropriate pediatric scoring system. The secondary objective was to evaluate the changes in surgical management induced by the proposed scoring system. Methods: A single-center prospective 5-year study was conducted from March 2016 to December 2021, including 99 children with a mean age of 7.2 years (±3.7), with pathological preoperative sleep recordings and undergoing DISE. The distribution of all upper airway obstructive sites was studied. Results: Adenoids (A) were the most frequent obstructive site (63% of patients), and the nasal cavities (N) and the larynx (L) were other frequent obstructive sites. These sites are not explored by the VOTE scoring system, leading to the creation of the nose, adenoids, velum, oropharynx, tongue, epiglottis, larynx (NAVOTEL) scoring system. NAVOTEL was significantly correlated with the severity of obstructive sleep apnea-hypopnea syndrome (OSAS) (ρ = 0.2; p = 0.04) and highlighted obstructive sites in 6/9 patients with VOTE = 0. Of these patients, 4 had a complete obstructive site, and 3 had a multisite obstruction. VOTE indicated 8 additional surgical actions; NAVOTEL indicated 50 other actions compared to clinical examination. The NAVOTEL scoring system was exhaustive regarding surgical indications for OSAS. Conclusions: The NAVOTEL scoring system is exhaustive in pediatric DISE and correlated to OSAS severity. It should be preferred in pediatric DISE.
MeSH term(s)	Humans ; Child ; Prospective Studies ; Polysomnography ; Endoscopy ; Sleep ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/surgery ; Syndrome
Language	English
Publishing date	2023-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	632784-9
ISSN	1099-0496 ; 8755-6863
ISSN (online)	1099-0496
ISSN	8755-6863
DOI	10.1002/ppul.26408
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Zs.A 2143: Show issues

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Article ; Online: Obstructive Sleep-Disordered Breathing in Infants with Normal Awake Clinical Examination: Contribution of Drug-Induced Sleep Endoscopy.

Rossi, Marie-Eva / Le Treut, Claire / Allali, Laure / Mazenq, Julie / Nicollas, Richard / Moreddu, Eric

Indian journal of pediatrics

2023

Abstract: Objectives: To determine the cause of obstructive sleep-disordered breathing using drug-induced sleep endoscopy (DISE) in infants without co-morbidities and with normal clinical examination.: Methods: This prospective study was conducted between ... ...

Abstract	Objectives: To determine the cause of obstructive sleep-disordered breathing using drug-induced sleep endoscopy (DISE) in infants without co-morbidities and with normal clinical examination. Methods: This prospective study was conducted between December 2019 and June 2022 (31 mo). All infants referred for obstructive sleep-disordered breathing with normal clinical examination and flexible laryngoscopy were included and underwent DISE. The location of the obstructive sites was scored similarly according to the NAVOTEL scoring system, previously established and validated by authors' team. Results: Thirty-two infants were included. DISE identified an obstructive site in 94% of cases. The mean age was 16.4 mo, and the median was 16.7 mo. The obstructive sites found were isolated sleep laryngomalacia (37.4%), adenotonsillar hypertrophy (21.8%), isolated adenoidal hypertrophy (6.3%), adenotonsillar hypertrophy associated with sleep laryngomalacia (6.3%), circumferential upper airway narrowing (6.3%), glossoptosis (6.3%), isolated inferior turbinate hypertrophy (3.1%), adenoidal and tongue base hypertrophy (3.1%), and adenoidal hypertrophy with sleep laryngomalacia (3.1%). No obstructive causes could be found in 2 cases (6.3%). DISE identified an obstructive site in 30/32 patients (93.8%) and guided the surgical management in 26/32 cases (81.3%) during the same general anesthesia. The infants without surgical obstacles were referred for medical treatment. Conclusions: DISE is an excellent diagnostic and pre-therapeutic tool in infants with no apparent cause at the awake examination to identify the obstructive sites and guide the treatment.
Language	English
Publishing date	2023-10-18
Publishing country	India
Document type	Journal Article
ZDB-ID	218231-2
ISSN	0973-7693 ; 0019-5456
ISSN (online)	0973-7693
ISSN	0019-5456
DOI	10.1007/s12098-023-04873-6
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Article ; Online: Delayed haemolytic transfusion reaction in paediatric patients with sickle cell disease: A retrospective study in a French national reference centre.

Rossi, Marica / Pirenne, France / Le Roux, Enora / Smaïne, Djamel / Belloy, Marie / Eyssette-Guerreau, Stéphanie / Couque, Nathalie / Holvoet, Laurent / Ithier, Ghislaine / Brousse, Valentine / Koehl, Bérengère / Faye, Albert / Benkerrou, Malika / Missud, Florence

British journal of haematology

2022 Volume 201, Issue 1, Page(s) 125–132

Abstract: ... of patients had painful crisis. Profound anaemia (median 49 g/L), low reticulocyte count (median 140 ×10 ...

Abstract	Delayed haemolytic transfusion reaction (DHTR) is a life-threatening haemolytic anaemia following red blood cell transfusion in patients with sickle cell disease, with only scarce data in children. We retrospectively analysed 41 cases of DHTR in children treated between 2006 and 2020 in a French university hospital. DHTR manifested at a median age of 10.5 years, symptoms occurred a median of 8 days after transfusion performed for an acute event (63%), before surgery (20%) or in a chronic transfusion programme (17%). In all, 93% of patients had painful crisis. Profound anaemia (median 49 g/L), low reticulocyte count (median 140 ×10
MeSH term(s)	Humans ; Child ; Retrospective Studies ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/therapy ; Blood Transfusion ; Stroke/prevention & control ; Transfusion Reaction/etiology
Language	English
Publishing date	2022-12-21
Publishing country	England
Document type	Journal Article
ZDB-ID	80077-6
ISSN	1365-2141 ; 0007-1048
ISSN (online)	1365-2141
ISSN	0007-1048
DOI	10.1111/bjh.18605
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Article ; Online: The right parasternal window: when Doppler-beam alignment may be life-saving in patients with aortic valve stenosis.

Benfari, Giovanni / Mantovani, Francesca / Romero-Brufau, Santiago / Setti, Martina / Rossi, Andrea / Ribichini, Flavio L / Nistri, Stefano / Clavel, Marie-Annick

Journal of cardiovascular medicine (Hagerstown, Md.)

2020 Volume 21, Issue 10, Page(s) 831–834

Abstract: The need for multiple transducer positions, especially from right parasternal windows, is consistently mentioned in the recommendations for the accurate measurement of peak velocities across a stenotic aortic valve, but yet poorly adopted.We performed ... ...

Abstract	: The need for multiple transducer positions, especially from right parasternal windows, is consistently mentioned in the recommendations for the accurate measurement of peak velocities across a stenotic aortic valve, but yet poorly adopted.We performed a subanalysis of the largest prospective series on the right parasternal acoustic windows in patients with aortic stenosis (330 consecutive) to calculate the degree of misalignment and estimate the potential outcome implication of this often-forgotten approach.The right parasternal view was highly feasible with an average estimated misalignment from the apical view of 14 ± 16 degree; in 10 cases, an estimated misalignment >40 degree. Right parasternal assessment (vs. apical alone) provided a significant reclassification from moderate to severe or even very-severe aortic valve stenosis. Considering a wellestablished survival benefit provided by either percutaneous or surgical valve replacement in patients with severe aortic stenosis the reclassification would result in approximately 1 life-year saved for every 30-35 patients in whom parasternal view were effectively utilized.
MeSH term(s)	Aortic Valve/diagnostic imaging ; Aortic Valve/physiopathology ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/therapy ; Clinical Decision-Making ; Echocardiography, Doppler ; Feasibility Studies ; Hemodynamics ; Humans ; Patient Positioning ; Predictive Value of Tests ; Prognosis ; Severity of Illness Index
Language	English
Publishing date	2020-05-13
Publishing country	United States
Document type	Letter
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000000971
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Zs.A 5210: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 559: Show issues

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Article ; Online: A new set of international Leptosphaeria maculans isolates as a resource for elucidation of the basis and evolution of blackleg disease on Brassica napus

Van de Wouw, Angela P. / Scanlan, Jack L. / Al‐Mamun, Hawlader A. / Balesdent, Marie‐Hélène / Bousset, Lydia / Burketová, Lenka / Rio Mendoza, Luis del / Fernando, W. G. Dilantha / Franke, Coreen / Howlett, Barbara J. / Huang, Yong‐Ju / Jones, E. Eirian / Koopmann, Birger / Lob, Suhaizan / Mirabadi, Ali Z. / Nugent, Bridgit C. / Peng, Gary / Rossi, Franco R. / Schreuder, Huibrecht /

Tabone, Annie R. / Van Coller, Gert J. / Batley, Jacqueline / Idnurm, Alexander

Plant Pathology. 2024 Jan., v. 73, no. 1 p.170-185

2024

Abstract: A collection of isolates of the fungi Leptosphaeria maculans and L. biglobosa, which cause blackleg ... of 226 isolates (205 L. maculans and 21 L. biglobosa) from 11 countries. The genomes of all 205 L ... in those countries. Analyses of the single‐nucleotide polymorphism (SNP) diversity within these L. maculans isolates ...

Abstract	A collection of isolates of the fungi Leptosphaeria maculans and L. biglobosa, which cause blackleg disease on Brassica napus (canola/oilseed rape) and other Brassicaceae species, was assembled to represent the global diversity of these pathogens and a resource for international research. The collection consists of 226 isolates (205 L. maculans and 21 L. biglobosa) from 11 countries. The genomes of all 205 L. maculans isolates were sequenced, and the distribution and identity of avirulence gene alleles were determined based on genotypic information and phenotypic reactions on B. napus lines that hosted specific resistance genes. Whilst the frequencies of some avirulence alleles were consistent across each of the regions, others differed dramatically, potentially reflecting the canola/oilseed rape cultivars grown in those countries. Analyses of the single‐nucleotide polymorphism (SNP) diversity within these L. maculans isolates revealed geographical separation of the populations. This "open access" resource provides a standardized set of isolates that can be used to define the basis for how these fungal pathogens cause disease, and as a tool for discovery of new resistance traits in Brassica species.
Keywords	Brassica napus ; Plenodomus lingam ; canola ; cultivars ; evolution ; fungi ; genes ; phenotype ; plant pathology ; single nucleotide polymorphism
Language	English
Dates of publication	2024-01
Size	p. 170-185.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	415941-x
ISSN	1365-3059 ; 0032-0862
ISSN (online)	1365-3059
ISSN	0032-0862
DOI	10.1111/ppa.13801
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: The spectral slope as a marker of excitation/inhibition ratio and cognitive functioning in multiple sclerosis.

Akbarian, Fahimeh / Rossi, Chiara / Costers, Lars / D'hooghe, Marie B / D'haeseleer, Miguel / Nagels, Guy / Van Schependom, Jeroen

Human brain mapping

2023 Volume 44, Issue 17, Page(s) 5784–5794

Abstract: Multiple sclerosis (MS) is a neurodegenerative disease characterized by neuronal and synaptic loss, resulting in an imbalance of excitatory and inhibitory synaptic transmission and potentially cognitive impairment. Current methods for measuring the ... ...

Abstract	Multiple sclerosis (MS) is a neurodegenerative disease characterized by neuronal and synaptic loss, resulting in an imbalance of excitatory and inhibitory synaptic transmission and potentially cognitive impairment. Current methods for measuring the excitation/inhibition (E/I) ratio are mostly invasive, but recent research combining neurocomputational modeling with measurements of local field potentials has indicated that the slope with which the power spectrum of neuronal activity captured by electro- and/or magnetoencephalography rolls off, is a non-invasive biomarker of the E/I ratio. A steeper roll-off is associated with a stronger inhibition. This novel method can be applied to assess the E/I ratio in people with multiple sclerosis (pwMS), detect the effect of medication such as benzodiazepines, and explore its utility as a biomarker for cognition. We recruited 44 healthy control subjects and 95 pwMS who underwent resting-state magnetoencephalographic recordings. The 1/f spectral slope of the neural power spectra was calculated for each subject and for each brain region. As expected, the spectral slope was significantly steeper in pwMS treated with benzodiazepines (BZDs) compared to pwMS not receiving BZDs (p = .01). In the sub-cohort of pwMS not treated with BZDs, we observed a steeper slope in cognitively impaired pwMS compared to cognitively preserved pwMS (p = .01) and healthy subjects (p = .02). Furthermore, we observed a significant correlation between 1/f spectral slope and verbal and spatial working memory functioning in the brain regions located in the prefrontal and parietal cortex. In this study, we highlighted the value of the spectral slope in MS by quantifying the effect of benzodiazepines and by putting it forward as a potential biomarker of cognitive deficits in pwMS.
MeSH term(s)	Humans ; Multiple Sclerosis/complications ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/psychology ; Neurodegenerative Diseases ; Cognition/physiology ; Benzodiazepines/pharmacology ; Benzodiazepines/therapeutic use ; Biomarkers
Chemical Substances	Benzodiazepines (12794-10-4) ; Biomarkers
Language	English
Publishing date	2023-09-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1197207-5
ISSN	1097-0193 ; 1065-9471
ISSN (online)	1097-0193
ISSN	1065-9471
DOI	10.1002/hbm.26476
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Zs.A 4028: Show issues

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Article ; Online: Clinical and economic impact of pharmacist interventions in an ambulatory hematology-oncology department.

de Grégori, Jonathan / Pistre, Pauline / Boutet, Meredith / Porcher, Laura / Devaux, Madeline / Pernot, Corinne / L Chrétien, Marie / Rossi, Cédric / Manfredi, Sylvain / Dalac, Sophie / Gueneau, Pauline / Boulin, Mathieu

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2020 Volume 26, Issue 5, Page(s) 1172–1179

Abstract: Objectives: To evaluate clinical and financial impact of pharmacist interventions in an ambulatory adult hematology-oncology department.: Methods: All cancer patients receiving a first injectable immuno- and/or chemotherapy regimen were included in ... ...

Abstract	Objectives: To evaluate clinical and financial impact of pharmacist interventions in an ambulatory adult hematology-oncology department. Methods: All cancer patients receiving a first injectable immuno- and/or chemotherapy regimen were included in this prospective study over a one-year period. The clinical impact of pharmacist interventions made by two clinical pharmacists was rated using the Clinical Economic and Organizational tool. Financial impact was calculated through cost savings and cost avoidance.
MeSH term(s)	Aged ; Aged, 80 and over ; Ambulatory Care Facilities/organization & administration ; Cost Savings ; Cost-Benefit Analysis ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/drug therapy ; Pharmacists/organization & administration ; Pharmacy Service, Hospital/economics ; Prospective Studies
Language	English
Publishing date	2020-04-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/1078155220915763
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Article ; Online: Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus.

Bailly, Julie / Del Rossi, Natalie / Runtz, Léonie / Li, Jing-Jing / Park, DaWoon / Scherrer, Grégory / Tanti, Arnaud / Birling, Marie-Christine / Darcq, Emmanuel / Kieffer, Brigitte L

eNeuro

2020 Volume 7, Issue 3

Abstract: The mu-opioid receptor (MOR) modulates nociceptive pathways and reward processing, and mediates the strong analgesic and addictive properties of both medicinal as well as abused opioid drugs. MOR function has been extensively studied, and tools to ... ...

Abstract	The mu-opioid receptor (MOR) modulates nociceptive pathways and reward processing, and mediates the strong analgesic and addictive properties of both medicinal as well as abused opioid drugs. MOR function has been extensively studied, and tools to manipulate or visualize the receptor protein are available. However, circuit mechanisms underlying MOR-mediated effects are less known, because genetic access to MOR-expressing neurons is lacking. Here we report the generation of a knock-in
MeSH term(s)	Animals ; Habenula/metabolism ; Integrases/genetics ; Mice ; Morphine/pharmacology ; Neurons/metabolism ; Receptors, Opioid, mu/genetics ; Receptors, Opioid, mu/metabolism
Chemical Substances	Receptors, Opioid, mu ; Morphine (76I7G6D29C) ; Cre recombinase (EC 2.7.7.-) ; Integrases (EC 2.7.7.-)
Language	English
Publishing date	2020-05-29
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2800598-3
ISSN	2373-2822 ; 2373-2822
ISSN (online)	2373-2822
ISSN	2373-2822
DOI	10.1523/ENEURO.0433-19.2020
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Article: Antimicrobial Resistance in the Environment: Towards Elucidating the Roles of Bioaerosols in Transmission and Detection of Antibacterial Resistance Genes.

George, Paul B L / Rossi, Florent / St-Germain, Magali-Wen / Amato, Pierre / Badard, Thierry / Bergeron, Michel G / Boissinot, Maurice / Charette, Steve J / Coleman, Brenda L / Corbeil, Jacques / Culley, Alexander I / Gaucher, Marie-Lou / Girard, Matthieu / Godbout, Stéphane / Kirychuk, Shelley P / Marette, André / McGeer, Allison / O'Shaughnessy, Patrick T / Parmley, E Jane /

Simard, Serge / Reid-Smith, Richard J / Topp, Edward / Trudel, Luc / Yao, Maosheng / Brassard, Patrick / Delort, Anne-Marie / Larios, Araceli D / Létourneau, Valérie / Paquet, Valérie E / Pedneau, Marie-Hélène / Pic, Émilie / Thompson, Brooke / Veillette, Marc / Thaler, Mary / Scapino, Ilaria / Lebeuf, Maria / Baghdadi, Mahsa / Castillo Toro, Alejandra / Cayouette, Amélia Bélanger / Dubois, Marie-Julie / Durocher, Alicia F / Girard, Sarah B / Diaz, Andrea Katherín Carranza / Khalloufi, Asmaâ / Leclerc, Samantha / Lemieux, Joanie / Maldonado, Manuel Pérez / Pilon, Geneviève / Murphy, Colleen P / Notling, Charly A / Ofori-Darko, Daniel / Provencher, Juliette / Richer-Fortin, Annabelle / Turgeon, Nathalie / Duchaine, Caroline

Antibiotics (Basel, Switzerland)

2022 Volume 11, Issue 7

Abstract: Antimicrobial resistance (AMR) is continuing to grow across the world. Though often thought of as a mostly public health issue, AMR is also a major agricultural and environmental problem. As such, many researchers refer to it as the preeminent One Health ...

Abstract	Antimicrobial resistance (AMR) is continuing to grow across the world. Though often thought of as a mostly public health issue, AMR is also a major agricultural and environmental problem. As such, many researchers refer to it as the preeminent One Health issue. Aerial transport of antimicrobial-resistant bacteria via bioaerosols is still poorly understood. Recent work has highlighted the presence of antibiotic resistance genes in bioaerosols. Emissions of AMR bacteria and genes have been detected from various sources, including wastewater treatment plants, hospitals, and agricultural practices; however, their impacts on the broader environment are poorly understood. Contextualizing the roles of bioaerosols in the dissemination of AMR necessitates a multidisciplinary approach. Environmental factors, industrial and medical practices, as well as ecological principles influence the aerial dissemination of resistant bacteria. This article introduces an ongoing project assessing the presence and fate of AMR in bioaerosols across Canada. Its various sub-studies include the assessment of the emissions of antibiotic resistance genes from many agricultural practices, their long-distance transport, new integrative methods of assessment, and the creation of dissemination models over short and long distances. Results from sub-studies are beginning to be published. Consequently, this paper explains the background behind the development of the various sub-studies and highlight their shared aspects.
Language	English
Publishing date	2022-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics11070974
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