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Article: Clinical utility of CLL-IPI scoring system in Pakistani Chronic Lymphocytic Patients: A single center experience.

Hameed, Aisha / Sajid, Nadia / Fayyaz, Muhammad / Khaliq, Shagufta

2024 Volume 40, Issue 4, Page(s) 701–705

Abstract: Objectives: To determine validity of the CLL International prognostic index (IPI) scoring system in Pakistani chronic lymphocytic leukemia patients, as the validity and universal applicability of various prognostic scoring systems such as the CLL-IPI ... ...

Abstract	Objectives: To determine validity of the CLL International prognostic index (IPI) scoring system in Pakistani chronic lymphocytic leukemia patients, as the validity and universal applicability of various prognostic scoring systems such as the CLL-IPI remains a challenge, particularly in under-developed countries like Pakistan. Methods: This prospective single center study was conducted at Department of Hematology, University of Health Sciences, Lahore and included sixty patients with CLL diagnosed between July, 2019 to July, 2022. Patients were followed for a period of two years and 02 year overall survival (OS) was noted. Risk stratification was conducted according to CLL-IPI prognostic model. Results: Among 60 patients, the mean age was 60±11years. Advanced Binet stage B+C and elevated β2-microglobulin >3.5mg/L was observed in 73.3% and 38.3% patients respectively. The estimated median 02 years OS was 16.5 months (95% CI: 10-20 months). In total, 40 of 60 CLL patients (67%) were accessible for follow-up analyses. For the present CLL cohort, 25% patients (n = 10) were classified as CLL-IPI low risk and intermediate risk group, 35% (n = 14) as high risk and 15% (n = 06) as very high-risk group. However, this classification of patients according to CLL-IPI did not yield significant differences in terms of OS ( Conclusion: To conclude, clinical validation of CLL-IPI scoring system could not be established for the present CLL cohort and needs to be evaluated in further studies with larger sample size.
Language	English
Publishing date	2024-02-26
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.40.4.8703
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Article: Fabricating Planar Perovskite Solar Cells through a Greener Approach.

Sajid, Sajid / Alzahmi, Salem / Tabet, Nouar / Haik, Yousef / Obaidat, Ihab M

Nanomaterials (Basel, Switzerland)

2024 Volume 14, Issue 7

Abstract: High-quality perovskite thin films are typically produced via solvent engineering, which results in efficient perovskite solar cells (PSCs). Nevertheless, the use of hazardous solvents like precursor solvents (N-Methyl-2-pyrrolidone (NMP), dimethyl ... ...

Abstract	High-quality perovskite thin films are typically produced via solvent engineering, which results in efficient perovskite solar cells (PSCs). Nevertheless, the use of hazardous solvents like precursor solvents (N-Methyl-2-pyrrolidone (NMP), dimethyl sulfoxide (DMSO), dimethylformamide (DMF), gamma-butyrolactone (GBL)) and antisolvents (chlorobenzene (CB), dibutyl ether (DEE), diethyl ether (Et
Language	English
Publishing date	2024-03-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano14070594
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prevalence, molecular characterization and antibiogram of Mycoplasma bovis isolated from milk in Pakistan.

Jabbar, A / Ashraf, M / Rahman, S U / Sajid, M S

Polish journal of veterinary sciences

2023 Volume 26, Issue 3, Page(s) 461–471

Abstract: ... The present study was aimed for the isolation, molecular characterization and antibiogram determination of M ... biochemical tests were performed for further confirmation of isolated M. bovis. Out of total 400 milk samples ... was performed for molecular characterization of isolated M. bovis strains. Out of total 400 milk ...

Abstract	Mycoplasma bovis is a highly contagious pathogen that causes clinical or subclinical mastitis. The present study was aimed for the isolation, molecular characterization and antibiogram determination of M. bovis from raw milk samples. Milk samples were collected randomly from lactating cows and buffaloes from different tehsils of district Faisalabad, Pakistan. Samples were inoculated on modified Hayflick medium and biochemical tests were performed for further confirmation of isolated M. bovis. Out of total 400 milk samples, 184 (46%) samples were found positive for culture method. The 16S-rRNA gene polymerase chain reaction was performed for molecular characterization of isolated M. bovis strains. Out of total 400 milk samples, 240 (60%) positive for M. bovis through PCR method were examined. The 16S-rRNA gene PCR positive isolated M. bovis strains were sequenced and results were compared using Maximum-likelihood method and sequenced strains of M. bovis were aligned and analyzed by Clustal W software. Antibiogram of isolated M. bovis strains was analyzed by disc diffusion assay against eight commonly used antibiotics. Tylosin (30μg) and Tilmicosin (15ug) showed inhibition zones of 32.34 ± 1.10 mm and 17.12 ± 0.93 mm respectively against isolated M. bovis which were found sensitive. Isolated M. bovis was found resistant to other commonly used antibiotics. Statistical analysis revealed that p-value was < 0.05 and the odds ratio was >1.0 at 95% CI. This study complemented the lack of epidemiological knowledge of molecular characterization, comparative effectiveness and resistance trends of isolated M. bovis strains against commonly used antibiotics.
MeSH term(s)	Female ; Animals ; Cattle ; Milk ; Mycoplasma bovis/genetics ; Pakistan/epidemiology ; Prevalence ; Lactation ; Mastitis, Bovine/epidemiology ; Anti-Bacterial Agents/pharmacology ; Bison ; Buffaloes ; Cattle Diseases
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-09-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2860634-6
ISSN	2300-2557 ; 1505-1773
ISSN (online)	2300-2557
ISSN	1505-1773
DOI	10.24425/pjvs.2023.145054
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Stability analysis of chaotic generalized Lotka-Volterra system via active compound difference anti-synchronization method.

Chaudhary, Harindri / Sajid, Mohammad / Kaushik, Santosh / Allahem, Ali

Mathematical biosciences and engineering : MBE

2023 Volume 20, Issue 5, Page(s) 9410–9422

Abstract: This work deals with a systematic approach for the investigation of compound difference anti-synchronization (CDAS) scheme among chaotic generalized Lotka-Volterra biological systems (GLVBSs). First, an active control strategy (ACS) of nonlinear type is ... ...

Abstract	This work deals with a systematic approach for the investigation of compound difference anti-synchronization (CDAS) scheme among chaotic generalized Lotka-Volterra biological systems (GLVBSs). First, an active control strategy (ACS) of nonlinear type is described which is specifically based on Lyapunov's stability analysis (LSA) and master-slave framework. In addition, the biological control law having nonlinear expression is constructed for attaining asymptotic stability pattern for the error dynamics of the discussed GLVBSs. Also, simulation results through MATLAB environment are executed for illustrating the efficacy and correctness of considered CDAS approach. Remarkably, our attained analytical outcomes have been in outstanding conformity with the numerical outcomes. The investigated CDAS strategy has numerous significant applications to the fields of encryption and secure communication.
Language	English
Publishing date	2023-05-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2265126-3
ISSN	1551-0018 ; 1551-0018
ISSN (online)	1551-0018
ISSN	1551-0018
DOI	10.3934/mbe.2023413
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Improvement of Polyethylene Glycol, Sorbitol, Mannitol, and Sucrose-Induced Osmotic Stress Tolerance through Modulation of the Polyamines, Proteins, and Superoxide Dismutase Activity in Potato

Sajid, Zahoor Ahmad / Aftab, Faheem

International journal of agronomy. 2022 Sept. 10, v. 2022

2022

Abstract: ... induced by various concentrations of sorbitol, mannitol (0, 0.025, 0.05, 0.10, or 0.15 M), sucrose (0, 2 ... 1.0 cm) from healthy in vitro-grown potato plantlets were inoculated on Murashige and Skoog’s medium ... of incubation exhibited a severe reduction in most of the growth parameters at 0.10 and 0.15 M of sorbitol and ...

Abstract	The present study was planned to investigate the changes in morphological and biochemical parameters of in vitro-grown potato (cultivar Cardinal and Desiree) plants under osmotic stress conditions induced by various concentrations of sorbitol, mannitol (0, 0.025, 0.05, 0.10, or 0.15 M), sucrose (0, 2, 3, 4, 6, and 8%), and polyethylene glycol (PEG: MW-4000: 0, 5, 10, 15, and 20%). Nodal segments (ca. 1.0 cm) from healthy in vitro-grown potato plantlets were inoculated on Murashige and Skoog’s medium consisting of various levels of above mentioned drought stress-inducing agents. Data was recorded on 60ᵗʰ day of incubation exhibited a severe reduction in most of the growth parameters at 0.10 and 0.15 M of sorbitol and mannitol, respectively, and at 5–10% PEG. Similar results were observed when the sucrose level varied from 3% except for the number of roots and plant dry weight, which exhibited an increase in increasing the sucrose level. Data collected for total soluble protein content and activity of an antioxidant enzyme (superoxide dismutase) unveiled an overall increasing trend in osmotically stressed potato plants suggesting their major action in detoxification of active oxygen species produced under osmotic stress. Polyamines (putrescine, spermidine, and spermine) increased significantly in both the cultivars of potato by using osmotic stress-inducing agent in the present investigation indicating their positive role in stress alleviation. Overall results indicated that potato cultivar Desiree was more stress-tolerant than the cultivar Cardinal.
Keywords	active oxygen species ; agronomy ; antioxidant enzymes ; cultivars ; drought ; mannitol ; osmotic stress ; plantlets ; polyethylene glycol ; potatoes ; protein content ; putrescine ; sorbitol ; spermidine ; spermine ; stress tolerance ; sucrose ; superoxide dismutase
Language	English
Dates of publication	2022-0910
Publishing place	Hindawi
Document type	Article
ZDB-ID	2548961-6
ISSN	1687-8167
ISSN	1687-8167
DOI	10.1155/2022/5158768
Database	NAL-Catalogue (AGRICOLA)

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Article: Guidelines for Fabricating Highly Efficient Perovskite Solar Cells with Cu

Sajid, Sajid / Alzahmi, Salem / Salem, Imen Ben / Obaidat, Ihab M

Nanomaterials (Basel, Switzerland)

2022 Volume 12, Issue 19

Abstract: Organic hole transport materials (HTMs) have been frequently used to achieve high power conversion efficiencies (PCEs) in regular perovskite solar cells (PSCs). However, organic HTMs or their ingredients are costly and time-consuming to manufacture. ... ...

Abstract	Organic hole transport materials (HTMs) have been frequently used to achieve high power conversion efficiencies (PCEs) in regular perovskite solar cells (PSCs). However, organic HTMs or their ingredients are costly and time-consuming to manufacture. Therefore, one of the hottest research topics in this area has been the quest for an efficient and economical inorganic HTM in PSCs. To promote efficient charge extraction and, hence, improve overall efficiency, it is crucial to look into the desirable properties of inorganic HTMs. In this context, a simulation investigation using a solar cell capacitance simulator (SCAPS) was carried out on the performance of regular PSCs using inorganic HTMs. Several inorganic HTMs, such as nickel oxide (NiO), cuprous oxide (Cu
Language	English
Publishing date	2022-09-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano12193315
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Perovskite-Surface-Confined Grain Growth for High-Performance Perovskite Solar Cells.

Sajid, Sajid / Alzahmi, Salem / Salem, Imen Ben / Obaidat, Ihab M

Nanomaterials (Basel, Switzerland)

2022 Volume 12, Issue 19

Abstract: The conventional post-annealing (CPA) process is frequently employed and regarded a crucial step for high-quality perovskite thin-films. However, most researchers end up with unwanted characteristics because controlling the evaporation rate of perovskite ...

Abstract	The conventional post-annealing (CPA) process is frequently employed and regarded a crucial step for high-quality perovskite thin-films. However, most researchers end up with unwanted characteristics because controlling the evaporation rate of perovskite precursor solvents during heat treatment is difficult. Most perovskite thin-films result in rough surfaces with pinholes and small grains with multiple boundaries, if the evaporation of precursor solvents is not controlled in a timely manner, which negatively affects the performance of perovskite solar cells (PSCs). Here, we present a surface-confined post-annealing (SCPA) approach for controlling the evaporation of perovskite precursor solvents and promoting crystallinity, homogeneity, and surface morphology of the resulting perovskites. The SCPA method not only modulates the evaporation of residual solvents, resulting in pinhole-free thin-films with large grains and fewer grain boundaries, but it also reduces recombination sites and facilitates the transport of charges in the resulting perovskite thin-films. When the method is changed from CPA to SCPA, the power conversion efficiency of PSC improves from 18.94% to 21.59%. Furthermore, as compared to their CPA-based counterparts, SCPA-based PSCs have less hysteresis and increased long-term stability. The SCPA is a potentially universal method for improving the performance and stability of PSCs by modulating the quality of perovskite thin-films.
Language	English
Publishing date	2022-09-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano12193352
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Lead-Free Perovskite Homojunction-Based HTM-Free Perovskite Solar Cells: Theoretical and Experimental Viewpoints.

Sajid, Sajid / Alzahmi, Salem / Salem, Imen Ben / Park, Jongee / Obaidat, Ihab M

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 6

Abstract: Simplifying the design of lead-free perovskite solar cells (PSCs) has drawn a lot of interest due to their low manufacturing cost and relative non-toxic nature. Focus has been placed mostly on reducing the toxic lead element and eliminating the ... ...

Abstract	Simplifying the design of lead-free perovskite solar cells (PSCs) has drawn a lot of interest due to their low manufacturing cost and relative non-toxic nature. Focus has been placed mostly on reducing the toxic lead element and eliminating the requirement for expensive hole transport materials (HTMs). However, in terms of power conversion efficiency (PCE), the PSCs using all charge transport materials surpass the environmentally beneficial HTM-free PSCs. The low PCEs of the lead-free HTM-free PSCs could be linked to poorer hole transport and extraction as well as lower light harvesting. In this context, a lead-free perovskite homojunction-based HTM-free PSC was investigated, and the performance was then assessed using a Solar Cell Capacitance Simulator (SCAPS). A two-step method was employed to fabricate lead-free perovskite homojunction-based HTM-free PSCs in order to validate the simulation results. The simulation results show that high hole mobility and a narrow band gap of cesium tin iodide (CsSnI
Language	English
Publishing date	2023-03-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13060983
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Diethanolamine Modified Perovskite-Substrate Interface for Realizing Efficient ESL-Free PSCs.

Sajid, Sajid / Alzahmi, Salem / Wei, Dong / Salem, Imen Ben / Park, Jongee / Obaidat, Ihab M

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 2

Abstract: Simplifying device layout, particularly avoiding the complex fabrication steps and multiple high-temperature treatment requirements for electron-selective layers (ESLs) have made ESL-free perovskite solar cells (PSCs) attractive. However, the poor ... ...

Abstract	Simplifying device layout, particularly avoiding the complex fabrication steps and multiple high-temperature treatment requirements for electron-selective layers (ESLs) have made ESL-free perovskite solar cells (PSCs) attractive. However, the poor perovskite/substrate interface and inadequate quality of solution-processed perovskite thin films induce inefficient interfacial-charge extraction, limiting the power conversion efficiency (PCEs) of ESL-free PSCs. A highly compact and homogenous perovskite thin film with large grains was formed here by inserting an interfacial monolayer of diethanolamine (DEA) molecules between the perovskite and ITO substrate. In addition, the DEA created a favorable dipole layer at the interface of perovskite and ITO substrate by molecular adsorption, which suppressed charge recombination. Comparatively, PSCs based on DEA-treated ITO substrates delivered PCEs of up to 20.77%, one of the highest among ESL-free PSCs. Additionally, this technique successfully elongates the lifespan of ESL-free PSCs as 80% of the initial PCE was maintained after 550 h under AM 1.5 G irradiation at ambient temperature.
Language	English
Publishing date	2023-01-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13020250
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: TCP BBR-n: Increased throughput for wireless-AC networks.

Ahsan, Muhammad / Muhammad, Sajid S

PloS one

2023 Volume 18, Issue 12, Page(s) e0295576

Abstract: Google proposed a new TCP congestion control algorithm (CCA), Bottleneck Bandwidth and Round-trip propagation time (BBR) which has opened up new dimensions in congestion control. BBR tries to operate near Kleinrock's operating point to avoid excessive ... ...

Abstract	Google proposed a new TCP congestion control algorithm (CCA), Bottleneck Bandwidth and Round-trip propagation time (BBR) which has opened up new dimensions in congestion control. BBR tries to operate near Kleinrock's operating point to avoid excessive queue formation at the bottleneck and to use the link bandwidth optimally. BBR creates a model of the network path by measuring the bottleneck bandwidth and minimum round-trip time (RTT) to maximize the delivery rate and minimize latency. BBR v2 is an updated version of BBR which addresses many shortcomings of the original BBR (BBR v1) such as interprotocol fairness, RTT fairness, and excessive retransmissions. However, BBR v2 has certain limitations in its operation in IEEE 802.11ac (Wi-Fi 5) networks. The default BBR v2 limits the throughput of Wi-Fi 5 and an increased latency has been observed. This is because the Wi-Fi 5 frame aggregation logic is underutilized and fewer frames are being sent to the Wi-Fi 5 interface. In this paper, we have proposed BBR-n (BBR new) which provides better throughput than the generic BBR v2 in the Wi-Fi 5 networks. Real-time experiments were performed over a physical testbed using Flent to confirm that BBR-n achieves over double throughput as compared to generic BBR v2 and reduced latency in networks as compared to pure loss-based variants such as Cubic and Reno.
MeSH term(s)	Algorithms ; Drugs, Generic ; Kidney ; Physical Examination ; Reading Frames
Chemical Substances	Drugs, Generic
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0295576
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