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  1. Book ; Online ; E-Book: Complications in Uveitis

    Pichi, Francesco / Neri, Piergiorgio

    2020  

    Abstract: This book focuses on secondary conditions aggravating uveitis. In addition to diagnosing, treating, and managing uveitis as an entity, particular attention is given to the pathogenesis of complications arising from ocular inflammation, prevention and ... ...

    Author's details edited by Francesco Pichi, Piergiorgio Neri
    Abstract This book focuses on secondary conditions aggravating uveitis. In addition to diagnosing, treating, and managing uveitis as an entity, particular attention is given to the pathogenesis of complications arising from ocular inflammation, prevention and treatment thereof. The chapters trace the course of a particular complication, its cause and importantly how to avoid it. Leading expert specialist explain a variety of occurring secondary conditions and their management. Inflammatory diseases causing these complications are briefly touched; the main focus will be the pathogenesis of the actual complication, prevention and treatment.This multi-disciplinary approach to complications of uveitis offers the reader, the tools to prevent or how to correctly manage these. Being of special interest to the uveitis specialist, this book also will be of value for all those with an interest in secondary conditions of ocular inflammations.
    Keywords Ophthalmology
    Subject code 617.72
    Language English
    Size 1 online resource (X, 288 p. 89 illus., 73 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-28392-5 ; 3-030-28391-7 ; 978-3-030-28392-6 ; 978-3-030-28391-9
    DOI 10.1007/978-3-030-28392-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: COVID, the end of pandemic and vaccine-induced Uveitis: is this the showdown?

    Neri, Piergiorgio / Pichi, Francesco

    International ophthalmology

    2023  Volume 43, Issue 12, Page(s) 4395–4397

    MeSH term(s) Humans ; Pandemics ; COVID-19/epidemiology ; Uveitis/chemically induced ; Uveitis/epidemiology
    Language English
    Publishing date 2023-10-06
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-023-02879-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Eye in systemic diseases.

    Roszkowska, Anna M / Fogagnolo, Paolo / Neri, Piergiorgio

    Frontiers in medicine

    2023  Volume 10, Page(s) 1171238

    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1171238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dancing in the eye: dynamic optical coherence tomography to distinguish different retinal microglia populations.

    Pichi, Francesco / Neri, Piergiorgio / Moreno-Rodriguez, Laura / Carreño, Ester

    International ophthalmology

    2024  Volume 44, Issue 1, Page(s) 165

    MeSH term(s) Humans ; Tomography, Optical Coherence/methods ; Microglia ; Fluorescein Angiography/methods
    Language English
    Publishing date 2024-03-30
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-024-03051-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unraveling the Complexities of Severe Acute Respiratory Syndrome Coronavirus 2: A Comprehensive Ophthalmic and Systemic Perspective.

    Neri, Piergiorgio / Perez, Yanny / Agarwal, Aniruddha / Pichi, Francesco

    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

    2024  

    Abstract: The editorial explores the profound implications of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, which emerged in December 2019 and rapidly evolved into a global health crisis. Despite initial focus on respiratory symptoms, ... ...

    Abstract The editorial explores the profound implications of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic, which emerged in December 2019 and rapidly evolved into a global health crisis. Despite initial focus on respiratory symptoms, the virus revealed significant ocular implications, prompting a reevaluation of the eye's role in its transmission, diagnosis, and systemic effects. The paradoxical nature of SARS-CoV-2-simultaneously novel and familiar within the coronavirus family-has been central to guiding the global medical response, including the swift development of vaccines. The pandemic has intensified research into the eye's susceptibility to viral infections, enhancing our understanding of virus-host interactions and the systemic impacts of viral diseases. The editorial delves into the pathophysiology of SARS-CoV-2, highlighting its potential to trigger autoinflammatory and autoimmune reactions with significant ocular repercussions. It examines the rapid vaccine development and deployment, the associated ocular side effects, and the ongoing research necessary to mitigate these outcomes. As the World Health Organization declared the end of COVID-19 as a public health emergency, the focus has shifted toward understanding the virus's long-term implications, including its effects on ocular health. This work underscores the critical role of interdisciplinary collaboration in addressing the systemic impacts of viral infections. It emphasizes the importance of ophthalmology in the broader context of public health and highlights the need for continued vigilance, research, and adaptation in a postpandemic world. The editorial calls for an integrated approach to health care, emphasizing the lessons learned from the SARS-CoV-2 pandemic to prepare for future health challenges, with a particular focus on the intersection of virology, immunology, and ophthalmology.
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1237021-6
    ISSN 1557-7732 ; 1080-7683
    ISSN (online) 1557-7732
    ISSN 1080-7683
    DOI 10.1089/jop.2024.0037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Acute syphilitic posterior placoid chorioretinitis: when the great mimicker cannot pretend any more; new insight of an old acquaintance.

    Neri, Piergiorgio / Pichi, Francesco

    Journal of ophthalmic inflammation and infection

    2022  Volume 12, Issue 1, Page(s) 9

    Abstract: Purpose: To review the multimodal imaging patterns of Acute Syphilitic Posterior Placoid Chorioretinitis (ASPPC).: Methods: A systematic review.: Results: Syphilis has started to attract the attention of researchers once again due to recent surges, ...

    Abstract Purpose: To review the multimodal imaging patterns of Acute Syphilitic Posterior Placoid Chorioretinitis (ASPPC).
    Methods: A systematic review.
    Results: Syphilis has started to attract the attention of researchers once again due to recent surges, with The World Health Organization (WHO) reporting around 12 million new cases per year. When left untreated, syphilis has a mortality rate of 8-58%, with a higher death rate in males. Eye manifestations occur both in secondary and tertiary stages of syphilis, although ocular involvement may occur at any stage of the disease. Syphilis has been always recognized as "the great mimicker" since it can have multiple clinical patterns of presentation. However, Acute Syphilitic Posterior Placoid Chorioretinitis (ASPPC) represents the typical pattern of the disease and can be easily distinguished. In addition, the advent of modern technologies and the progress made in multimodal imaging have provided more details on its identikit: the pattern of pre-retinal, retinal, retinochoroidal and optic nerve involvement can be identified before going through the laboratory work-up for a correct and appropriate investigation of the disease.
    Conclusion: This review highlights the peculiar pattern of ASPPC, by reporting the diagnostic process made by all the imaging techniques used for a correct multimodal imaging assessment.
    Language English
    Publishing date 2022-02-22
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2592309-2
    ISSN 1869-5760
    ISSN 1869-5760
    DOI 10.1186/s12348-022-00286-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Fundus autofluorescence in uveitis: from pathogenesis to imaging interpretation.

    Saturno, Maria Carmela / Neri, Piergiorgio / Pichi, Francesco

    International ophthalmology

    2023  Volume 43, Issue 11, Page(s) 4359–4371

    Abstract: Purpose: This review aims to summarize the current fundus autofluorescence (FAF) ailment for diagnosis and follow-up of uveitis.: Methods: A thorough literature search was performed in the PubMed database.: Results: FAF maps the retinal pigment ... ...

    Abstract Purpose: This review aims to summarize the current fundus autofluorescence (FAF) ailment for diagnosis and follow-up of uveitis.
    Methods: A thorough literature search was performed in the PubMed database.
    Results: FAF maps the retinal pigment epithelium's (RPE) health. Therefore, several posterior infectious and non. This fast, easy-to-perform, noninvasive technique can detect and manage infectious uveitis.
    Conclusions: FAF serves to understand pathophysiologic mechanisms of uveitis and is a valuable prognostic indicator of themselves.
    MeSH term(s) Humans ; Fundus Oculi ; Uveitis/diagnosis ; Uveitis/pathology ; Fluorescein Angiography/methods ; Retinal Pigment Epithelium/pathology
    Language English
    Publishing date 2023-07-07
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-023-02803-1
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  8. Article ; Online: Tubulointerstitial Nephritis and Uveitis Syndrome in the United Arab Emirates.

    Pichi, Francesco / Aljeneibi, Shaikha / Neri, Piergiorgio

    Ocular immunology and inflammation

    2023  , Page(s) 1–5

    Abstract: Purpose: To report the first series of tubulointerstitial nephritis (TINU) syndrome from the Middle East.: Methods: We retrospectively included patients with elevated urine beta-2 microglobulin, and a diagnosis of TINU based on anterior uveitis with ... ...

    Abstract Purpose: To report the first series of tubulointerstitial nephritis (TINU) syndrome from the Middle East.
    Methods: We retrospectively included patients with elevated urine beta-2 microglobulin, and a diagnosis of TINU based on anterior uveitis with or without posterior involvement. Multimodal imaging, duration of follow-up, local and systemic treatment used were recorded.
    Results: 24 eyes of 12 patients (8 male, mean age 20.3 years) met the criteria for TINU. The most common posterior segment clinical finding was optic nerve head edema (41.7%), while on fluorescein angiography 58.3% and 75% of eyes had peripheral vascular and optic disc leakage, respectively. The mean follow-up was 2.5 years and all patients required immunomodulatory treatment.
    Conclusions: Middle Eastern patients with TINU seem to have a male predominance, a bimodal distribution in terms of age, and present with ocular involvement first. Multimodal imaging is paramount in detecting subclinical inflammation and tailoring immunomodulatory treatment.
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2178939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Focal Posterior Herpetic Retinitis.

    AlAli, Sahar H / Neri, Piergiorgio / Pichi, Francesco

    Ocular immunology and inflammation

    2023  , Page(s) 1–4

    Abstract: Despite having 20/20 vision, a 17-year-old Emirati female presented with central visual changes in her left eye. These changes were attributed to a dull foveal reflex with pigmentary alterations. Retinal pigment epithelium (RPE) mottling at the macula ... ...

    Abstract Despite having 20/20 vision, a 17-year-old Emirati female presented with central visual changes in her left eye. These changes were attributed to a dull foveal reflex with pigmentary alterations. Retinal pigment epithelium (RPE) mottling at the macula level, attenuating the ellipsoid zone, and a hyper-reflective line connecting the RPE to the outer nuclear layer was observed through spectral domain optical coherence tomography (SD-OCT) of the left eye. In the presence of negative results from laboratory evaluations, the patient was started on oral prednisolone. The medication induced an increased reflectivity of the inner layers on SD-OCT, which turned into a full-thickness macular retinitis with vitreous inflammation, causing a visual decrease to 20/80. A vitreous tap confirmed a positive result for HSV-1, and the patient was prescribed oral valacyclovir 3 g. This treatment led to a resolution of the retinitis and a restoration of the patient's vision to 20/25.
    Language English
    Publishing date 2023-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2230261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Optical coherence tomography angiography in birdshot chorioretinopathy.

    Pichi, Francesco / Lembo, Andrea / Nucci, Paolo / Neri, Piergiorgio

    European journal of ophthalmology

    2023  , Page(s) 11206721231203265

    Abstract: Purpose: To describe the retinal vascular changes in birdshot chorioretinopathy (BSCR) using optical coherence tomography angiography (OCTA) and to compare them with changes in macular thickness.: Methods: In this multicenter study, patients with a ... ...

    Abstract Purpose: To describe the retinal vascular changes in birdshot chorioretinopathy (BSCR) using optical coherence tomography angiography (OCTA) and to compare them with changes in macular thickness.
    Methods: In this multicenter study, patients with a diagnosis of BSCR and a positive HLA-A29 underwent fluorescein angiography, spectral domain optical coherence tomography (SD-OCT), and OCTA. The foveal avascular zone (FAZ) and the area of capillary non-perfusion were manually measured by two examiners in fluorescein angiography (FA) and 3 × 3-mm OCTA images of the superficial retinal layer. These measurements were compared to central retinal thickness. To calculate normal capillary density, we collected data from 22 controls who had OCTA performed on one visit only.
    Results: A total of 44 eyes with BSCR were enrolled. The mean automated parafoveal superficial capillary density in BSCR eyes was 0.47 ± 0.03. The differences between the foveal capillary density of BSCR patients and healthy subjects were statistically significant (
    Conclusion: Our study demonstrates the potential contribution of OCTA as a new non-invasive imaging technology that monitors disease activity in BSCR patients.
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721231203265
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