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  1. Article ; Online: The frozen elephant trunk: seeking a more definitive treatment for acute type a aortic dissection.

    Papakonstantinou, Nikolaos A / Martinez-Lopez, Daniel / Chung, Jennifer Chia-Ying

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  

    Abstract: Objectives: Conventional treatment for type A aortic dissection includes replacement of the ascending aorta with an open distal anastomosis in the hemiarch position. The frozen elephant trunk is a hybrid technique that extends the repair to the ... ...

    Abstract Objectives: Conventional treatment for type A aortic dissection includes replacement of the ascending aorta with an open distal anastomosis in the hemiarch position. The frozen elephant trunk is a hybrid technique that extends the repair to the descending thoracic aorta. The goal is to improve resolution of malperfusion syndrome and to induce positive aortic remodelling and reduce the need for reintervention on the downstream aorta. We aim to summarize the data on the short and long-term outcomes of this technique.
    Methods: A thorough search of the literature was conducted isolating all articles dealing with aortic remodelling after the use of frozen elephant trunk in case of type A acute aortic dissection. Keywords "aortic dissection", "frozen elephant trunk", "aortic remodelling" and "false lumen thrombosis" were used. Data for type B and chronic aortic dissections were excluded.
    Results: Frozen elephant trunk use favorably influences aortic remodelling. The main advantages lie in the exclusion of distal entry tears in either the aortic arch or descending aorta thus restoring antegrade blood flow in the true lumen and inducing false lumen thrombosis. False lumen thrombosis is not only induced at the level of the stent deployment but also lower in the distal descending aorta. Moreover, it offers an adequate landing zone in the mid-descending aorta for second-stage endovascular or open surgical aortic repair, if needed.
    Conclusions: Frozen elephant trunk can be advantageous in the treatment of acute type A aortic dissection dealing with extended aortic pathology.
    Language English
    Publishing date 2024-04-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezae176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to Roberto et al.

    Papakonstantinou, Nikolaos A / Rorris, Filippos-Paschalis

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2021  Volume 60, Issue 1, Page(s) 208

    Language English
    Publishing date 2021-04-16
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezab088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply to Acharya et al.

    Papakonstantinou, Nikolaos A / Rorris, Filippos-Paschalis

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2021  Volume 60, Issue 1, Page(s) 204–205

    Language English
    Publishing date 2021-01-30
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezab002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Perceval S valve. Making the good better… or optimal?

    Papakonstantinou, Nikolaos A / Baikoussis, Nikolaos G

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2019  Volume 57, Issue 4, Page(s) 812–813

    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Bioprosthesis ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Humans ; Registries
    Language English
    Publishing date 2019-10-18
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezz315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Perceval S valve empire: healing the Achilles' heel of sutureless aortic valves.

    Papakonstantinou, Nikolaos A / Baikoussis, Nikolaos G / Dedeilias, Panagiotis

    The Journal of cardiovascular surgery

    2021  Volume 62, Issue 6, Page(s) 625–631

    Abstract: Aortic valve replacement is the treatment of choice concerning aortic valve disease. Excellent short- and long-term clinical results are reported. Patients referred for aortic valve replacement are getting older and older, so bioprosthetic valves play a ... ...

    Abstract Aortic valve replacement is the treatment of choice concerning aortic valve disease. Excellent short- and long-term clinical results are reported. Patients referred for aortic valve replacement are getting older and older, so bioprosthetic valves play a more central role worldwide. However, patient comorbidities are also increased more often rendering patients unsuitable for open conventional aortic valve replacement. As a result, transcatheter aortic valve implantation has become the treatment of choice in patients at very high surgical risk. However, the percutaneous technique is related to major disadvantages provided that the diseased native valve is left in place. Its durability is also uncertain. More recently, sutureless Perceval S valve bioprosthesis has gained ground in the field of aortic stenosis therapy filling the gap between conventional aortic valve replacement and transcatheter approach. Excellent hemodynamic and clinical results are reported. Its deployment is performed under direct view and ischemic and overall operative times are significantly decreased. Five-year follow-up results are also optimal. However, the "Achilles' heel" of sutureless technology is increased rates of postoperative permanent pacemaker implantation requirement compared to conventional approach. The incidence of this complication varies in literature. Patient-related factors such as preoperative conduction disorders, older age and short membranous septum are predictors of postoperative pacemaker requirement. However, several technical modifications regarding manufacturer recommendations can be adopted to mitigate this complication. Appropriate annular decalcification, higher guiding sutures placement, reduced balloon pressure and duration and avoiding of oversizing can contribute to prevent from this complication.
    MeSH term(s) Aortic Valve/diagnostic imaging ; Aortic Valve/physiopathology ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/surgery ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/physiopathology ; Arrhythmias, Cardiac/prevention & control ; Arrhythmias, Cardiac/therapy ; Bioprosthesis ; Cardiac Pacing, Artificial ; Heart Valve Prosthesis ; Hemodynamics ; Humans ; Pacemaker, Artificial ; Prosthesis Design ; Recovery of Function ; Risk Assessment ; Risk Factors ; Sutureless Surgical Procedures/adverse effects ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/instrumentation ; Treatment Outcome
    Language English
    Publishing date 2021-05-20
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.21.11608-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Two life-threatening complications during chronic total occlusion management.

    Maritsa, Dimitra / Gavrielatos, Gerasimos / Dimopoulos, Antonios / Patsourakos, Nikolaos / Papakonstantinou, Nikolaos / Pisimisis, Evaggelos

    Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

    2022  Volume 18, Issue 1, Page(s) 81–82

    Language English
    Publishing date 2022-04-11
    Publishing country Poland
    Document type Journal Article
    ISSN 1734-9338
    ISSN 1734-9338
    DOI 10.5114/aic.2022.115282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Elective replacement of the ascending aorta: is the 5.5-cm threshold appropriate? The insidious, small aorta.

    Papakonstantinou, Nikolaos A / Rorris, Filippos-Paschalis

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2020  Volume 59, Issue 3, Page(s) 554–561

    Abstract: Objectives: As thoracic aortic aneurysm disease continues to cause significant morbidity and mortality in the general population, the cardiovascular community continues the search for the golden threshold of elective surgical replacement of the ... ...

    Abstract Objectives: As thoracic aortic aneurysm disease continues to cause significant morbidity and mortality in the general population, the cardiovascular community continues the search for the golden threshold of elective surgical replacement of the ascending aorta.
    Methods: Thoracic aortic aneurysm is a common disease, classified within the 20 most common causes of death in patients over 65 years old. Once aortic complications like dissection or rupture occur, they can prove fatal. Prophylactic surgical replacement of the ascending aorta remains the mainstay of treatment to prevent these complications. Current American and European guidelines agree that the threshold for the diameter for elective replacement of the ascending aorta in non-syndromic, asymptomatic aneurysmal disease is 5.5 cm. Overall, aortic dissection is related to poor prognosis, thus making early intervention paramount.
    Results: There is a critical size above which the risk of dissection or rupture becomes extremely high. However, a significant post-dissection increase in diameter is reported, thus rendering the predissection aortic diameter well below the current threshold for elective surgical replacement of the ascending aorta. Moreover, it is widely reported that the majority of acute aortic dissections would not meet the criteria for prophylactic surgery prior to dissection. Additionally, elective surgical ascending aortic replacement in the current era shows a significantly improved risk-benefit ratio, which justifies a more aggressive approach in the management of aortic aneurysmal disease.
    Conclusions: As a result, there is a lot of discussion in the literature about the requirement of a leftward shifting of the surgical threshold for elective aortic replacement.
    MeSH term(s) Aged ; Aneurysm, Dissecting/surgery ; Aorta/surgery ; Aorta, Thoracic ; Aortic Aneurysm/surgery ; Aortic Aneurysm, Thoracic/surgery ; Elective Surgical Procedures ; Humans
    Language English
    Publishing date 2020-11-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezaa387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Total arterial revascularization: A superior method of cardiac revascularization.

    Papakonstantinou, Nikolaos A / Baikoussis, Nikolaos G

    Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

    2016  Volume 57, Issue 3, Page(s) 152–156

    Abstract: For over 40 years, the left internal thoracic artery has been used as the gold standard for myocardial revascularization and anastomosis over the left anterior descending artery due to its excellent patency rates. However, the right internal thoracic ... ...

    Abstract For over 40 years, the left internal thoracic artery has been used as the gold standard for myocardial revascularization and anastomosis over the left anterior descending artery due to its excellent patency rates. However, the right internal thoracic artery behaves in the same manner as the left, also having excellent long-term patency. Hence, no patient should be deprived of the benefits of total arterial revascularization allowed by the bilateral use of both internal thoracic arteries.
    MeSH term(s) Coronary Artery Disease/surgery ; Humans ; Myocardial Revascularization/methods ; Survival Analysis ; Treatment Outcome
    Language English
    Publishing date 2016-06-24
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2215027-4
    ISSN 2241-5955 ; 1109-9666
    ISSN (online) 2241-5955
    ISSN 1109-9666
    DOI 10.1016/j.hjc.2016.06.002
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  9. Article: Surgical Management of a Pancreaticopleural Fistula After Failed Endoscopic Therapy.

    Koliakos, Nikolaos / Papakonstantinou, Dimitrios / Reppas, Lazaros / Bakopoulos, Anargyros / Tzortzis, Andrianos / Polymeros, Dimitrios / Oikonomopoulos, Nikolaos / Pikoulis, Emmanouil / Martikos, Georgios

    Cureus

    2022  Volume 14, Issue 3, Page(s) e23241

    Abstract: Inflammatory diseases of the pancreas or pancreatic trauma result in ductal cell disruption, which in turn may lead to leakage of pancreatic fluid, mostly in the retroperitoneal space. Pancreatopleural fistulas are uncommonly encountered following ... ...

    Abstract Inflammatory diseases of the pancreas or pancreatic trauma result in ductal cell disruption, which in turn may lead to leakage of pancreatic fluid, mostly in the retroperitoneal space. Pancreatopleural fistulas are uncommonly encountered following pancreatic injury; however, they often prove a difficult problem to manage. Herein, we present a rare case of a 68-year-old male suffering from a pancreaticopleural fistula (PF) between the pancreatic tail and the left pleural space one year following splenectomy for trauma. About three months after percutaneous drainage of a left pleural effusion and left upper quadrant abdominal collection and endoscopic pancreatic duct stent placement, surgical management was decided. Distal pancreatectomy and Roux-en-Y drainage of the pancreatic remnant were successfully performed.
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.23241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Aortocoronary saphenous vein graft aneurysm misdiagnosed as aortic arch aneurysm.

    Papakonstantinou, Nikolaos A / Samiotis, Ilias / Kratimenos, Theodoros / Dedeilias, Panagiotis

    Annals of cardiac anaesthesia

    2021  Volume 24, Issue 2, Page(s) 247–249

    Abstract: Coronary artery bypass grafting is the mainstay of revascularization worldwide. However, the most widely used saphenous vein grafts are related to a number of late sequelae. Aortocoronary saphenous vein graft aneurysms mainly diagnosed incidentally are ... ...

    Abstract Coronary artery bypass grafting is the mainstay of revascularization worldwide. However, the most widely used saphenous vein grafts are related to a number of late sequelae. Aortocoronary saphenous vein graft aneurysms mainly diagnosed incidentally are one of these complications. Although rare, given the fatal risk of rupture if left untreated, management either with percutaneous intervention or open redo surgery should be considered. However, no guidelines are established in current scarce literature. Hereby, we present the successful percutaneous management of a huge saphenous vein graft aneurysm via coiling, avoiding the risks of repeat sternotomy.
    MeSH term(s) Aorta, Thoracic ; Aortic Aneurysm ; Coronary Artery Bypass ; Diagnostic Errors ; Humans ; Saphenous Vein/diagnostic imaging
    Language English
    Publishing date 2021-04-21
    Publishing country India
    Document type Case Reports
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.ACA_74_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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