Article ; Online: SARS-CoV-2 IgG antibody responses in New York City.
Diagnostic microbiology and infectious disease
2020 Volume 98, Issue 3, Page(s) 115128
Abstract: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes coronavirus disease 2019 (Covid-19) and has been declared a global pandemic by the World Health Organization. Total cases of SARS-CoV-2 worldwide exceed ... ...
| Abstract | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes coronavirus disease 2019 (Covid-19) and has been declared a global pandemic by the World Health Organization. Total cases of SARS-CoV-2 worldwide exceed 10.2 million, with over 503,000 deaths recorded. Little is known about the body's immune response to SARS-CoV-2 infection. In this paper, we describe SARS-CoV-2 IgG antibody responses in 28,523 patients from the New York City metropolitan area and report a SARS-CoV-2 IgG positivity rate of 44%, indicating the widespread nature of the pandemic in the city and state of New York. Additionally, for a subset of patients, we report on the correlation between SARS-CoV-2 patient symptom severity and level of SARS-CoV-2 IgG antibody found in the patient sample. |
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| MeSH term(s) | Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Antibody Formation/immunology ; Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Female ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Male ; New York City ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; SARS-CoV-2 ; Severity of Illness Index |
| Chemical Substances | Antibodies, Viral ; Immunoglobulin G |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-07-21 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 604920-5 |
| ISSN | 1879-0070 ; 0732-8893 |
| ISSN (online) | 1879-0070 |
| ISSN | 0732-8893 |
| DOI | 10.1016/j.diagmicrobio.2020.115128 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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