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  1. Article ; Online: Liposomes Enhance the Immunological Activity of Polygonatum Cyrtonema Hua Polysaccharides.

    Liu, Dong / Hou, Tingting / Geng, Chunye / Song, Lu / Hou, Xuefeng / Chen, Yanjun / Wang, Fang / Wang, Wei / Han, Bangxing / Gao, Leilei

    Journal of pharmaceutical sciences

    2024  

    Abstract: ... in their application. The purpose of this study was to optimize the preparation conditions of Polygonatum cyrtonema Hua ... This study provides a new idea for applying Polygonatum cyrtonema Hua polysaccharides (PCP) and references ...

    Abstract Poor stability and difficult uptake of natural polysaccharides have been the main problems in their application. The purpose of this study was to optimize the preparation conditions of Polygonatum cyrtonema Hua polysaccharides liposomes (PCPL) and to investigate the immune enhancement activity of PCPL in vitro and in vivo, with a view to discovering new ways of natural polysaccharide application. The optimal preparation conditions of PCPL were as follows: the adding amount of Tween 80 of 0.5 %, the ultrasound time of 2 min and the ultrasound times of once. Under these conditions, the entrapment efficiency, drug loading rate and particle size of PCPL were 38.033 %±0.050, 2.172 %±0.003 and 146 nm, which indicated that PCPL with small particle size could be prepared by the reverse-phase evaporation method. Furthermore, PCPL promoted proliferation, phagocytosis, and secretion of nitric oxide and related cytokines in RAW264.7 cells. Moreover, PCPL improved spleen and thymus indices, increased the number or proportion of red blood cells, platelets, and lymphocytes in the blood, and ameliorated spleen and thymus atrophy in immunosuppressed mice. This study provides a new idea for applying Polygonatum cyrtonema Hua polysaccharides (PCP) and references for studying other polysaccharides.
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3151-3
    ISSN 1520-6017 ; 0022-3549
    ISSN (online) 1520-6017
    ISSN 0022-3549
    DOI 10.1016/j.xphs.2024.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Effects of Dan-Shao-Hua-Xian on the expression of collagen type I and III in rats with hepatic fibrosis.

    Geng, Xiao-Xia / Yang, Qin / Xie, Ru-Jia / Luo, Xin-Hua / Li, Cheng-Xiu / Cheng, Ming-Liang

    Hepatobiliary & pancreatic diseases international : HBPD INT

    2004  Volume 3, Issue 4, Page(s) 558–563

    Abstract: ... of the extracellular matrix, which is mainly composed of collagens. Dan-Shao-Hua-Xian (DSHX) capsule, a traditional Chinese ...

    Abstract Background: Hepatic fibrosis is the common pathological change in various chronic liver diseases, and its major cause is the imbalance between the production and degradation of the extracellular matrix, which is mainly composed of collagens. Dan-Shao-Hua-Xian (DSHX) capsule, a traditional Chinese herbal compound, has shown marked preventive effects on hepatic fibrosis in rats in our previous studies. The present study was designed to further investigate its therapeutic actions on hepatic fibrosis in rats and its possible mechanisms.
    Methods: Eighty male Wistar rats were randomly divided into normal control group, hepatic fibrosis group, non-DSHX-treated group, low-dose-treated group, and high-dose-treated group. The rat models of hepatic fibrosis were established by subcutaneous injecton of CCl4, drinking alcohol, giving diet of hyperliprosis and hypoprotein for 8 weeks. The two DSHX-treated groups were treated respectively with low dose (0.5 g/kg) and high dose (1.0 g/kg) of DSHX capsule p.o. everyday for 8 weeks. At the end of the experiment, liver indexes were calculated in each group in addition to the levels of the serum hyaluronic acid and alanine aminotransferase. Their degree of hepatic fibrosis and urinary excretion of hydroxyproline and expression of collagen I, III were detected.
    Results: Comparison of the indexes of the hepatic fibrosis group and non-DSHX-treated group revealed that the liver indexes, levels of serum hyaluronic acid and alanine aminotransferase, and stage of hepatic fibrosis were all significantly reduced in the two DSHX treated groups. The urinary excretion of hydroxyproline was increased and the expression of collagen I and III in liver tissue was lessened. These alterations were more obviously observed in the high-dose-treated group.
    Conclusion: DSHX capsule has certain therapeutic effect on hepatic fibrosis in rats.
    MeSH term(s) Alanine Transaminase/blood ; Animals ; Collagen Type I/metabolism ; Collagen Type III/metabolism ; Drugs, Chinese Herbal/pharmacology ; Hyaluronic Acid/blood ; Hydroxyproline/urine ; Liver/pathology ; Liver Cirrhosis/blood ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Liver Cirrhosis/urine ; Male ; Medicine, Chinese Traditional ; Organ Size/drug effects ; Rats ; Rats, Wistar
    Chemical Substances Collagen Type I ; Collagen Type III ; Drugs, Chinese Herbal ; dan-shao-hua-xian ; Hyaluronic Acid (9004-61-9) ; Alanine Transaminase (EC 2.6.1.2) ; Hydroxyproline (RMB44WO89X)
    Language English
    Publishing date 2004-11
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2241386-8
    ISSN 1499-3872
    ISSN 1499-3872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Xin yi hua jian ji

    Zhu, Hengfu / Geng, Xiangyuan

    (Gu ji jin zhu xin yi cong shu ; 古籍今注新譯叢書)

    2002  

    Title variant Hua jian ji ; 花閒集
    Author's details Zhu heng fu zhu yi ; geng xiang yuan jiao yue
    Series title Gu ji jin zhu xin yi cong shu
    古籍今注新譯叢書
    Keywords Chinese poetry ; Ci (Chinese poetry)
    Language Chinese
    Dates of publication 2002-1998
    Size 2, 21, 16, 3, 617 p, 25 cm
    Edition Chu ban, er shua
    Publisher San min shu ju
    Publishing place Tai bei
    Document type Book
    Note Includes bibliographical references
    ISBN 9571427160 ; 9789571427164
    Database Former special subject collection: coastal and deep sea fishing

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  4. Article: Rapid Identification of the Multiple Absorbed Bioactive Components and Metabolites in Rat Serum after Oral Administration of Wu-Jia Sheng-Hua Capsule by UPLC-ESI-MS.

    Geng, Fang / Wang, Fashan / Zou, Taobo / Zhu, Kuiyuan / Ma, Wei / Tan, Guanghui / Zhang, Ning

    Journal of analytical methods in chemistry

    2013  Volume 2013, Page(s) 318961

    Abstract: To identify the compounds absorbed in rat serum after the oral administration of Wu-Jia Sheng-Hua ...

    Abstract To identify the compounds absorbed in rat serum after the oral administration of Wu-Jia Sheng-Hua (WJSH) capsule, a traditional Chinese medicine (TCM) compound prescription, an ultraperformance liquid chromatography coupled with electrospray ionization mass spectrometry (UPLC/ESI-MS) method, was established. The chromatographic separation of the absorbed compounds and metabolites was achieved with an ACQUITY UPLC BEH C18 column (2.1 mm × 50 mm, 1.7 μm) under a gradient elution. The mobile phase was composed of acetonitrile and water buffered with ammonium acetate (10 mM) and formic acid (0.1%, V/V). Twelve absorbed compounds and four metabolites were found. Seven of the absorbed compounds were identified by ESI-MS. The identification of absorbed compounds might be helpful for the better understanding of the mechanisms underlying the pharmacological effects of WJSH capsule.
    Language English
    Publishing date 2013-05-14
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2654178-6
    ISSN 2090-8873 ; 2090-8865
    ISSN (online) 2090-8873
    ISSN 2090-8865
    DOI 10.1155/2013/318961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rapid Identification of the Multiple Absorbed Bioactive Components and Metabolites in Rat Serum after Oral Administration of Wu-Jia Sheng-Hua Capsule by UPLC-ESI-MS

    Fang Geng / Fashan Wang / Taobo Zou / Kuiyuan Zhu / Wei Ma / Guanghui Tan / Ning Zhang

    Journal of Analytical Methods in Chemistry, Vol

    2013  Volume 2013

    Abstract: To identify the compounds absorbed in rat serum after the oral administration of Wu-Jia Sheng-Hua ...

    Abstract To identify the compounds absorbed in rat serum after the oral administration of Wu-Jia Sheng-Hua (WJSH) capsule, a traditional Chinese medicine (TCM) compound prescription, an ultraperformance liquid chromatography coupled with electrospray ionization mass spectrometry (UPLC/ESI-MS) method, was established. The chromatographic separation of the absorbed compounds and metabolites was achieved with an ACQUITY UPLC BEH C18 column (2.1 mm × 50 mm, 1.7 μm) under a gradient elution. The mobile phase was composed of acetonitrile and water buffered with ammonium acetate (10 mM) and formic acid (0.1%, V/V). Twelve absorbed compounds and four metabolites were found. Seven of the absorbed compounds were identified by ESI-MS. The identification of absorbed compounds might be helpful for the better understanding of the mechanisms underlying the pharmacological effects of WJSH capsule.
    Keywords Analytical chemistry ; QD71-142
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Book ; Online: Power Quality in Microgrids Based on Distributed Generators

    Chandra, Ambrish / Geng, Hua

    2019  

    Abstract: This book comprises ten articles covering different aspects of power quality issues in microgrids and distributed generation (DG) systems, including 1) Detection and estimation of power quality; 2) Modeling; 3) Harmonic control for DG systems and ... ...

    Abstract This book comprises ten articles covering different aspects of power quality issues in microgrids and distributed generation (DG) systems, including 1) Detection and estimation of power quality; 2) Modeling; 3) Harmonic control for DG systems and microgrids; 4) Stability improvements for microgrids. Different power quality phenomena and solution were studied in the included papers, such as harmonics, resonance, frequency deviation, voltage sag, and fluctuation. From a network point of view, some papers studied the harmonic and stability issues in standalone microgrids which are more likely to cause power quality problems. Other papers discussed the power quality problems in microgrids which are weakly interconnected with the main distribution grid. In view of the published papers, there is a trend that increasingly advanced modeling, analysis, and control schemes were applied in the studies. Moreover, the latest works focus not only on single-unit problems but also multiple units or network issues. Although some of the hot topics are not included, this book covers multiple aspects of the current power quality research frontier, and represents a particularly useful reference book for frontier researchers in this field
    Keywords Technology (General) ; Engineering (General). Civil engineering (General)
    Size 1 electronic resource (194 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note eng ; Open Access
    HBZ-ID HT020394904
    ISBN 9783039280063 ; 9783039280070 ; 3039280066 ; 3039280074
    DOI 10.3390/books978-3-03928-007-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Book ; Online ; E-Book: Statistical causal inferences and their applications in public health research

    He, Hua / Wu, Pan / Chen, Ding-Geng

    (ICSA book series in statistics)

    2016  

    Author's details Hua He, Pan Wu, Ding-Geng (Din) Chen editors
    Series title ICSA book series in statistics
    Keywords Causality ; Statistics as Topic ; Randomized Controlled Trials as Topic ; Models, Statistical
    Language English
    Size 1 Online-Ressource (xv, 321 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019471997
    ISBN 978-3-319-41259-7 ; 9783319412573 ; 3-319-41259-0 ; 3319412574
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article ; Online: Author Correction: Predicted reentrant melting of dense hydrogen at ultra-high pressures.

    Geng, Hua Y / Wu, Q

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 11595

    Language English
    Publishing date 2023-07-18
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-38003-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comments on "Regenerative effect of combined laser and human stem cell-conditioned medium therapy on hypertrophic burn scar".

    Geng, Qiu-Hua / Wang, Jun-Hua

    Burns : journal of the International Society for Burn Injuries

    2022  Volume 49, Issue 1, Page(s) 235–236

    MeSH term(s) Humans ; Culture Media, Conditioned ; Burns/therapy ; Burns/surgery ; Cicatrix, Hypertrophic/pathology ; Lasers ; Stem Cells/pathology ; Laser Therapy ; Treatment Outcome ; Lasers, Gas
    Chemical Substances Culture Media, Conditioned
    Language English
    Publishing date 2022-09-17
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 197308-3
    ISSN 1879-1409 ; 0305-4179
    ISSN (online) 1879-1409
    ISSN 0305-4179
    DOI 10.1016/j.burns.2022.08.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The thermoelectric properties of CdBr, CdI, and Janus Cd

    Wu, Yan-Ling / Yang, Qiu / Geng, Hua-Yun / Cheng, Yan

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 8, Page(s) 6956–6966

    Abstract: The investigation and development of high thermoelectric value materials has become a research hotspot in recent years. In this work, based on the density functional theory on the Perdew-Burke-Ernzerhof (GGA-PBE) level, the thermoelectric properties of ... ...

    Abstract The investigation and development of high thermoelectric value materials has become a research hotspot in recent years. In this work, based on the density functional theory on the Perdew-Burke-Ernzerhof (GGA-PBE) level, the thermoelectric properties of transition metal halides CdBr, Janus Cd
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05613a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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