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  1. Article ; Online: Striking a balance. Interview by Holger Breithaupt and Samuel Caddick.

    Long, Sharon R

    EMBO reports

    2010  Volume 11, Issue 2, Page(s) 82–85

    MeSH term(s) Bioelectric Energy Sources/supply & distribution ; Biotechnology/ethics ; Biotechnology/legislation & jurisprudence ; Climate Change ; Consensus ; Dissent and Disputes ; Government Regulation ; Humans ; Organisms, Genetically Modified ; Public Opinion ; Risk Assessment ; Science ; United States
    Language English
    Publishing date 2010-01-22
    Publishing country England
    Document type Interview
    ZDB-ID 2020896-0
    ISSN 1469-3178 ; 1469-221X
    ISSN (online) 1469-3178
    ISSN 1469-221X
    DOI 10.1038/embor.2009.285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5433: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 41: Show issues

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  2. Article ; Online: Tales of plagues and carnivals: Samuel R. Delany, AIDS, and the grammar of dissent.

    Long, Thomas Lawrence

    The Journal of medical humanities

    2013  Volume 34, Issue 2, Page(s) 213–226

    Abstract: ... African-American fantasy writer Samuel R. Delany, which rejected the rigid binarism of "safe" and "unsafe" sex ...

    Abstract While even today lesbian, gay, bisexual and transgender people might have cause to distrust the healthcare establishment, how much more fragile was the relationship between sexual minorities and health professionals in the first decade of the AIDS epidemic. Dissent from consensus healthcare and health research then was a question of survival in the face of political and medical intransigence. This article focuses on one version of AIDS dissent: The narrative representations of AIDS in fiction by the gay African-American fantasy writer Samuel R. Delany, which rejected the rigid binarism of "safe" and "unsafe" sex practices, Delany's evidence-based dissent. He also engaged in a related form of cultural dissent: speaking the unspeakably obscene, at a time when Silence = Death. Delany called into question both the inferential leaps based on limited epidemiological research that were represented in safer sex guidelines and the widespread public reticence about sexual behavior.
    MeSH term(s) Bioethical Issues ; HIV Infections/history ; History, 20th Century ; Homosexuality, Male ; Humans ; Male ; Medicine in Literature ; Patient Advocacy/history ; Professional-Patient Relations ; Safe Sex ; United States
    Language English
    Publishing date 2013-02-27
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 2017000-2
    ISSN 1573-3645 ; 1041-3545
    ISSN (online) 1573-3645
    ISSN 1041-3545
    DOI 10.1007/s10912-013-9209-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Homœopathy

    Long, Samuel

    The Homoeopathic physician

    2023  Volume 8, Issue 1, Page(s) 45–48

    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Successful Case of Ovariotomy.

    Long, Samuel

    The North-Western medical and surgical journal

    2023  Volume 6, Issue 3, Page(s) 103–107

    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Digital PCR: Methods and applications in infectious diseases.

    Long, Samuel

    Methods (San Diego, Calif.)

    2022  Volume 201, Page(s) 1–4

    MeSH term(s) Communicable Diseases/diagnosis ; Communicable Diseases/genetics ; Humans ; Polymerase Chain Reaction
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 1066584-5
    ISSN 1095-9130 ; 1046-2023
    ISSN (online) 1095-9130
    ISSN 1046-2023
    DOI 10.1016/j.ymeth.2022.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Correction: Long, S. SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and Perspectives.

    Long, Samuel

    Viruses

    2022  Volume 14, Issue 7

    Abstract: The author is no longer affiliated with the original institution "AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA", so the author wishes to change the affiliation to "Independent Researcher, ... ...

    Abstract The author is no longer affiliated with the original institution "AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA", so the author wishes to change the affiliation to "Independent Researcher, Clarksburg, MD 20871, USA" [...].
    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14071406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and Perspectives.

    Long, Samuel

    Viruses

    2021  Volume 13, Issue 10

    Abstract: SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important ...

    Abstract SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis. This review summarizes the recent progress on SARS-CoV-2 sgRNA identification, characterization, and application as a viral replication marker. The significance of these findings and potential future research areas of interest are discussed.
    MeSH term(s) Animals ; COVID-19/genetics ; COVID-19/metabolism ; Gene Expression/genetics ; Gene Expression Regulation, Viral/genetics ; Genome, Viral/genetics ; Genomics/methods ; Humans ; Pandemics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; Virus Replication
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-09-24
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13101923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In pursuit of sensitivity: Lessons learned from viral nucleic acid detection and quantification on the Raindance ddPCR platform.

    Long, Samuel

    Methods (San Diego, Calif.)

    2021  Volume 201, Page(s) 82–95

    Abstract: Sensitive PCR detection of viral nucleic acids plays a critical role in infectious disease research, diagnosis and monitoring. In the context of SARS-CoV-2 detection, recent reports indicate that digital PCR-based tests are significantly more sensitive ... ...

    Abstract Sensitive PCR detection of viral nucleic acids plays a critical role in infectious disease research, diagnosis and monitoring. In the context of SARS-CoV-2 detection, recent reports indicate that digital PCR-based tests are significantly more sensitive than traditional qPCR tests. Numerous factors can influence digital PCR reaction sensitivity. In this review, using a model for human HIV infection and the Raindance ddPCR platform as an example, we describe technical aspects that contribute to sensitive viral signal detection in DNA and RNA from tissue samples, which often harbor viral reservoirs and serve as better predictors of disease outcome and indicators of treatment efficacy.
    MeSH term(s) COVID-19/diagnosis ; HIV Infections/diagnosis ; Humans ; RNA, Viral/analysis ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2/genetics ; Sensitivity and Specificity
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-04-09
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural
    ZDB-ID 1066584-5
    ISSN 1095-9130 ; 1046-2023
    ISSN (online) 1095-9130
    ISSN 1046-2023
    DOI 10.1016/j.ymeth.2021.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: SARS-CoV-2 Subgenomic RNAs: Characterization, Utility, and Perspectives

    Long, Samuel

    Viruses. 2021 Sept. 24, v. 13, no. 10

    2021  

    Abstract: SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important ...

    Abstract SARS-CoV-2, the etiologic agent at the root of the ongoing COVID-19 pandemic, harbors a large RNA genome from which a tiered ensemble of subgenomic RNAs (sgRNAs) is generated. Comprehensive definition and investigation of these RNA products are important for understanding SARS-CoV-2 pathogenesis. This review summarizes the recent progress on SARS-CoV-2 sgRNA identification, characterization, and application as a viral replication marker. The significance of these findings and potential future research areas of interest are discussed.
    Keywords COVID-19 infection ; RNA ; Severe acute respiratory syndrome coronavirus 2 ; etiological agents ; genome ; pathogenesis ; virus replication
    Language English
    Dates of publication 2021-0924
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13101923
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Juniperus virginiana sourced from colder climates maintain higher ratios of soluble sugars to starch during cold acclimation.

    Harbol, Samuel C / Long, Randall W / Medeiros, Juliana S

    Tree physiology

    2023  

    Abstract: Non-structural carbohydrates (NSCs) are carbon compounds that serve a large variety of purposes, which makes it hard to disentangle how their concentrations change in response to environmental stress. Soluble sugars can accumulate in plants as metabolic ... ...

    Abstract Non-structural carbohydrates (NSCs) are carbon compounds that serve a large variety of purposes, which makes it hard to disentangle how their concentrations change in response to environmental stress. Soluble sugars can accumulate in plants as metabolic demand decreases, e.g. in response to drought or as seasonal temperatures decrease. Alternatively, actively allocating to NSCs could be beneficial in cold acclimation or periods of increased aridity because soluble sugars serve non-metabolic functions as cryoprotectants and in osmoregulation. We used Juniperus virginiana, a woody plant currently expanding its range, to investigate whether plants sourced from colder and more arid locations maintained higher concentrations of NSCs. We sourced three populations of J. virginiana from across an environmental gradient, and we compared these with the closely related Juniperus scopulorum. We grew the plants in a common garden in northeast Ohio, part of J. virginiana's historic range. We exposed the plants to a drought treatment during the summer and then measured NSC concentrations and cold hardiness as the plants acclimated to colder temperatures and shorter days. We found that individuals originating from the warmer, more southern, range edge were initially not as cold hardy as plants from the other source populations and only reached similar hardiness after prolonged low temperatures. We did not find an effect of drought on NSCs, although this may be due to other traits conferring a high level of drought tolerance in J. virginiana. Across all plants, the NSCs concentration increased over the cold acclimation period, specifically as sugars. Although the highest concentrations of sugars were found in plants from southern populations, the plants from colder environments maintained higher ratios of sugars to starch. These results highlight the importance of NSCs in cold acclimation, and that plants sourced from different climates showed different physiological responses to shortening days and low temperatures.
    Language English
    Publishing date 2023-09-21
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 743341-4
    ISSN 1758-4469 ; 0829-318X
    ISSN (online) 1758-4469
    ISSN 0829-318X
    DOI 10.1093/treephys/tpad115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4737: Show issues

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