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Article ; Online: Talking to Patients about the Influenza Vaccine.

Byrd, Katrina M

Rhode Island medical journal (2013)

2020 Volume 103, Issue 6, Page(s) 29–33

Abstract: Influenza is a significant cause of hospitalization and death in late fall and early spring, especially in our most vulnerable populations. Despite high mortality and morbidity of influenza infection, patients are still hesitant about getting the flu ... ...

Abstract	Influenza is a significant cause of hospitalization and death in late fall and early spring, especially in our most vulnerable populations. Despite high mortality and morbidity of influenza infection, patients are still hesitant about getting the flu vaccine each year. This article offers advice on educating our patients to address misconceptions and help them embrace this important seasonal vaccination.
MeSH term(s)	Humans ; Influenza Vaccines/therapeutic use ; Influenza, Human/prevention & control ; Parents/education ; Parents/psychology ; Patient Acceptance of Health Care/psychology ; Patient Acceptance of Health Care/statistics & numerical data ; Seasons ; United States
Chemical Substances	Influenza Vaccines
Keywords	covid19
Language	English
Publishing date	2020-08-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	419430-5
ISSN	2327-2228 ; 0363-7913
ISSN (online)	2327-2228
ISSN	0363-7913
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: COVID-19 in a Patient Presenting with Syncope and a Normal Chest X-ray.

Tapé, Chantal / Byrd, Katrina M / Aung, Su / Lonks, John R / Flanigan, Timothy P / Rybak, Natasha R

Rhode Island medical journal (2013)

2020 Volume 103, Issue 3, Page(s) 50–51

Abstract: SARS-CoV-2 is a novel virus that has now affected hundreds of thousands of individuals across the world. Amidst this global pandemic, maintaining a high index of suspicion, rapid testing capacity, and infection control measures are required to curtail ... ...

Abstract	SARS-CoV-2 is a novel virus that has now affected hundreds of thousands of individuals across the world. Amidst this global pandemic, maintaining a high index of suspicion, rapid testing capacity, and infection control measures are required to curtail the virus' rapid spread. While fever and respiratory symptoms have been commonly used to identify COVID-19 suspects, we present an elderly female who arrived to the hospital after a syncopal episode. She was afebrile with a normal chest X-ray and there was no suspicion of COVID-19. She then developed a fever and tested positive for COVID-19. Our unique case underscores the increasing diversity of COVID-19 presentations and potential for initial mis- diagnosis and delay in implementing proper precautions.
MeSH term(s)	Aged ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Diagnostic Errors ; Female ; Fever/etiology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Radiography, Thoracic ; SARS-CoV-2 ; Syncope/etiology
Keywords	covid19
Language	English
Publishing date	2020-03-26
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	419430-5
ISSN	2327-2228 ; 0363-7913
ISSN (online)	2327-2228
ISSN	0363-7913
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Efficacy and safety of sofosbuvir in the treatment of hep C among patients on hemodialysis: a systematic review and meta-analysis.

Shehadeh, Fadi / Kalligeros, Markos / Byrd, Katrina / Shemin, Douglas / Mylonakis, Eleftherios / Martin, Paul / D'Agata, Erika M C

Scientific reports

2020 Volume 10, Issue 1, Page(s) 14332

Abstract: Hepatitis C virus (HCV) infection among maintenance hemodialysis patients is implicated in increased morbidity and mortality compared to uninfected patients. Sofosbuvir (SOF)-based regimens may not be optimal among patients requiring hemodialysis. ... ...

Abstract	Hepatitis C virus (HCV) infection among maintenance hemodialysis patients is implicated in increased morbidity and mortality compared to uninfected patients. Sofosbuvir (SOF)-based regimens may not be optimal among patients requiring hemodialysis. Several studies, however, provide evidence that use of SOF among HCV-positive patients with renal impairment, is effective and safe. We searched Pubmed and Embase to identify studies reporting the efficacy and safety of SOF-based regimens for the treatment of HCV-positive patients on maintenance hemodialysis and performed a random effects meta-analysis. The overall pooled estimate of the efficacy of SOF-based therapy was 95% (95% CI 91-98%). The efficacy of the SOF-based regimen was 92% (95% CI 80-99%), 98% (95% CI 96-100%), and 100% (95% CI 95-100%) for the following doses: 400 mg on alternate days, 400 mg daily, and 200 mg daily, respectively. The most frequent adverse event was fatigue with a pooled prevalence of 16% (95% CI 5-29%), followed by anemia 15% (95% CI 3-31%), and nausea or vomiting 14% (95% CI 4-27%). Anemia was more prevalent in treatment regimens containing ribavirin (46%, 95% CI 33-59%) compared to ribavirin-free regimens (3%, 95% CI 0-9%). This study suggests that SOF-based regimens in the treatment of HCV infection among hemodialysis patients are both effective and safe.
MeSH term(s)	Antiviral Agents/therapeutic use ; Hepatitis C/complications ; Hepatitis C/drug therapy ; Humans ; Kidney Failure, Chronic/complications ; Sofosbuvir/therapeutic use
Chemical Substances	Antiviral Agents ; Sofosbuvir (WJ6CA3ZU8B)
Language	English
Publishing date	2020-08-31
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Systematic Review
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-71205-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: COVID-19 in a Patient Presenting with Syncope and a Normal Chest X-ray

Tapé, Chantal / Byrd, Katrina M / Aung, Su / Lonks, John R / Flanigan, Timothy P / Rybak, Natasha R

R I Med J (2013)

Abstract	SARS-CoV-2 is a novel virus that has now affected hundreds of thousands of individuals across the world. Amidst this global pandemic, maintaining a high index of suspicion, rapid testing capacity, and infection control measures are required to curtail the virus' rapid spread. While fever and respiratory symptoms have been commonly used to identify COVID-19 suspects, we present an elderly female who arrived to the hospital after a syncopal episode. She was afebrile with a normal chest X-ray and there was no suspicion of COVID-19. She then developed a fever and tested positive for COVID-19. Our unique case underscores the increasing diversity of COVID-19 presentations and potential for initial mis- diagnosis and delay in implementing proper precautions.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32226962
Database	COVID19

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Article ; Online: Efficacy and safety of sofosbuvir in the treatment of hep C among patients on hemodialysis

Fadi Shehadeh / Markos Kalligeros / Katrina Byrd / Douglas Shemin / Eleftherios Mylonakis / Paul Martin / Erika M. C. D’Agata

Scientific Reports, Vol 10, Iss 1, Pp 1-

a systematic review and meta-analysis

2020 Volume 10

Abstract: Abstract Hepatitis C virus (HCV) infection among maintenance hemodialysis patients is implicated in increased morbidity and mortality compared to uninfected patients. Sofosbuvir (SOF)-based regimens may not be optimal among patients requiring ... ...

Abstract	Abstract Hepatitis C virus (HCV) infection among maintenance hemodialysis patients is implicated in increased morbidity and mortality compared to uninfected patients. Sofosbuvir (SOF)-based regimens may not be optimal among patients requiring hemodialysis. Several studies, however, provide evidence that use of SOF among HCV-positive patients with renal impairment, is effective and safe. We searched Pubmed and Embase to identify studies reporting the efficacy and safety of SOF-based regimens for the treatment of HCV-positive patients on maintenance hemodialysis and performed a random effects meta-analysis. The overall pooled estimate of the efficacy of SOF-based therapy was 95% (95% CI 91–98%). The efficacy of the SOF-based regimen was 92% (95% CI 80–99%), 98% (95% CI 96–100%), and 100% (95% CI 95–100%) for the following doses: 400 mg on alternate days, 400 mg daily, and 200 mg daily, respectively. The most frequent adverse event was fatigue with a pooled prevalence of 16% (95% CI 5–29%), followed by anemia 15% (95% CI 3–31%), and nausea or vomiting 14% (95% CI 4–27%). Anemia was more prevalent in treatment regimens containing ribavirin (46%, 95% CI 33–59%) compared to ribavirin-free regimens (3%, 95% CI 0–9%). This study suggests that SOF-based regimens in the treatment of HCV infection among hemodialysis patients are both effective and safe.
Keywords	Medicine ; R ; Science ; Q
Subject code	616
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment.

International journal of geriatric psychiatry

2023 Volume 38, Issue 9, Page(s) e5992

Abstract: Background: Alzheimer disease (AD) is more prevalent in African American (AA) and Hispanic White (HIW) compared to Non-Hispanic White (NHW) individuals. Similarly, neuropsychiatric symptoms (NPS) vary by population in AD. This is likely the result of ... ...

Abstract	Background: Alzheimer disease (AD) is more prevalent in African American (AA) and Hispanic White (HIW) compared to Non-Hispanic White (NHW) individuals. Similarly, neuropsychiatric symptoms (NPS) vary by population in AD. This is likely the result of both sociocultural and genetic ancestral differences. However, the impact of these NPS on AD in different groups is not well understood. Methods: Self-declared AA, HIW, and NHW individuals were ascertained as part of ongoing AD genetics studies. Participants who scored higher than 0.5 on the Clinical Dementia Rating (CDR) Scale (CDR) were included. Group similarities and differences on Neuropsychiatric Inventory Questionnaire (NPI-Q) outcomes (NPI-Q total score, NPI-Q items) were evaluated using univariate ANOVAs and post hoc comparisons after controlling for sex and CDR stage. Results: Our sample consisted of 498 participants (26% AA; 30% HIW; 44% NHW). Overall, NPI-Q total scores differed significantly between our groups, with HIW having the highest NPI-Q total scores, and by AD stage as measured by CDR. We found no significant difference in NPI-Q total score by sex. There were six NPI-Q items with comparable prevalence in all groups and six items that significantly differed between the groups (Anxiety, Apathy, Depression, Disinhibition, Elation, and Irritability). Further, within the HIW group, differences were found between Puerto Rican and Cuban American Hispanics across several NPI-Q items. Finally, Six NPI-Q items were more prevalent in the later stages of AD including Agitation, Appetite, Hallucinations, Irritability, Motor Disturbance, and Nighttime Behavior. Conclusions: We identified differences in NPS among HIW, AA, and NHW individuals. Most striking was the high burden of NPS in HIW, particularly for mood and anxiety symptoms. We suggest that NPS differences may represent the impact of sociocultural influences on symptom presentation as well as potential genetic factors rooted in ancestral background. Given the complex relationship between AD and NPS it is crucial to discern the presence of NPS to ensure appropriate interventions.
MeSH term(s)	Humans ; Alzheimer Disease/genetics ; Alzheimer Disease/psychology ; Anxiety ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/psychology ; Ethnicity ; Hispanic or Latino ; Black or African American ; White
Language	English
Publishing date	2023-08-31
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	806736-3
ISSN	1099-1166 ; 0885-6230
ISSN (online)	1099-1166
ISSN	0885-6230
DOI	10.1002/gps.5992
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Article ; Online: Can Coastal Habitats Rise to the Challenge? Resilience of Estuarine Habitats, Carbon Accumulation, and Economic Value to Sea-Level Rise in a Puget Sound Estuary

Moritsch, Monica M. / Byrd, Kristin B. / Davis, Melanie / Good, Anthony / Drexler, Judith Z. / Morris, James T. / Woo, Isa / Windham-Myers, Lisamarie / Grossman, Eric / Nakai, Glynnis / Poppe, Katrina L. / Rybczyk, John M.

Estuaries and Coasts. 2022 Dec., v. 45, no. 8 p.2293-2309

2022

Abstract: ... accumulation up to 7.69 and 14.2 kg m⁻² and increased total economic value up to $373,000 and $710,000 ...

Abstract	Sea-level rise (SLR) and obstructions to sediment delivery pose challenges to the persistence of estuarine habitats and the ecosystem services they provide. Restoration actions and sediment management strategies may help mitigate such challenges by encouraging the vertical accretion of sediment in and horizontal migration of tidal forests and marshes. We used a process-based soil accretion model (Coastal Wetland Equilibrium Model) combined with a habitat classification model (MOSAICS) to estimate the effects of SLR, suspended sediment, and inland habitat migration on estuarine habitats, soil carbon accumulation, and economic value of climate change mitigation of carbon accumulation (social cost of carbon dioxide) in a macrotidal estuary in the northwest USA over 100 years (2011 to 2110). Under present-day sediment levels, we projected that after 100 years, most high salt marsh would remain with < 100 cm SLR, but substantial area converted to transitional (low) salt marsh and mudflat with ≥ 100 cm SLR. Increasing sediment availability increased the projected resilience of transitional salt marsh to SLR but did not prevent declines in high marsh area. Projected total carbon accumulation plateaued or declined with ≥ 100 cm SLR, yet the economic value of carbon accumulation continued to rise over time, suggesting that the value of this ecosystem service was resilient to SLR. Doubling or tripling sediment availability increased projected carbon accumulation up to 7.69 and 14.2 kg m⁻² and increased total economic value up to $373,000 and $710,000, respectively. Allowing marsh migration supported conversion of upland to freshwater marsh, with slight increases in carbon accumulation. These results inform climate adaptation planning for wetland managers seeking to understand the resilience of estuarine habitats and ecosystem services to SLR under multiple management strategies.
Keywords	carbon ; carbon dioxide ; climate ; climate change ; economic valuation ; ecosystem services ; ecosystems ; estuaries ; freshwater marshes ; habitats ; highlands ; migratory behavior ; models ; salt marshes ; sea level ; sediments ; soil ; soil carbon ; Northwestern United States ; Puget Sound
Language	English
Dates of publication	2022-12
Size	p. 2293-2309.
Publishing place	Springer US
Document type	Article ; Online
ZDB-ID	2229170-2
ISSN	1559-2731 ; 1559-2723
ISSN (online)	1559-2731
ISSN	1559-2723
DOI	10.1007/s12237-022-01087-5
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Possible Exposures Among Mpox Patients Without Reported Male-to-Male Sexual Contact - Six U.S. Jurisdictions, November 1-December 14, 2022.

Sharpe, J Danielle / Charniga, Kelly / Byrd, Katrina M / Stefanos, Ruth / Lewis, Linda / Watson, Jessica / Feldpausch, Amanda / Pavlick, Jessica / Hand, Julie / Sokol, Theresa / Ortega, Emma / Pathela, Preeti / Hennessy, Robin R / Dulcey, Melissa / McHugh, Lisa / Pietrowski, Michael / Perella, Dana / Shah, Seema / Maroufi, Azarnoush /

Taylor, Melanie / Cope, Anna / Belay, Ermias D / Ellington, Sascha / McCollum, Andrea M / Zilversmit Pao, Leah / Guagliardo, Sarah Anne J / Dawson, Patrick

MMWR. Morbidity and mortality weekly report

2023 Volume 72, Issue 35, Page(s) 944–948

Abstract: The extent to which the 2022 mpox outbreak has affected persons without a recent history of male-to-male sexual contact (MMSC) is not well understood. During November 1-December 14, 2022, CDC partnered with six jurisdictional health departments to ... ...

Abstract	The extent to which the 2022 mpox outbreak has affected persons without a recent history of male-to-male sexual contact (MMSC) is not well understood. During November 1-December 14, 2022, CDC partnered with six jurisdictional health departments to characterize possible exposures among mpox patients aged ≥18 years who did not report MMSC during the 3 weeks preceding symptom onset. Among 52 patients included in the analysis, 14 (27%) had a known exposure to a person with mpox, including sexual activity and other close intimate contact (eight) and household contact (six). Among 38 (73%) patients with no known exposure to a person with mpox, self-reported activities before illness onset included sexual activity and other close intimate contact (17; 45%), close face-to-face contact (14; 37%), attending large social gatherings (11; 29%), and being in occupational settings involving close skin-to-skin contact (10; 26%). These findings suggest that sexual activity remains an important route of mpox exposure among patients who do not report MMSC.
MeSH term(s)	Humans ; Male ; Adolescent ; Adult ; Mpox (monkeypox) ; Sexual Behavior ; Disease Outbreaks ; Methionine
Chemical Substances	methionylmethylsulfonium chloride (3493-12-7) ; Methionine (AE28F7PNPL)
Language	English
Publishing date	2023-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	412775-4
ISSN	1545-861X ; 0149-2195
ISSN (online)	1545-861X
ISSN	0149-2195
DOI	10.15585/mmwr.mm7235a2
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Article ; Online: Strategies to Increase Workforce Diversity in Pediatric Infectious Diseases.

Rogo, Tanya / Holland, Sabina / Fassiotto, Magali / Maldonado, Yvonne / Joseph, Tuhina / Ramilo, Octavio / Byrd, Katrina / Delair, Shirley

Journal of the Pediatric Infectious Diseases Society

2022 Volume 11, Issue Supplement_4, Page(s) S148–S154

Abstract: The number of physicians who are underrepresented in medicine within the pediatric infectious diseases workforce remains disproportionate compared to the US population. Physician workforce diversity plays an important role in reducing health care ... ...

Abstract	The number of physicians who are underrepresented in medicine within the pediatric infectious diseases workforce remains disproportionate compared to the US population. Physician workforce diversity plays an important role in reducing health care disparities. Pathways to careers in pediatric infectious diseases require that a diverse pool of students enter medicine and subsequently choose pediatric residency followed by subspecialty training. Efforts must be made to expose learners to pediatric infectious diseases earlier in the education timeline. Along with recruitment and creation of pathways, cultures of inclusivity must be created and fostered within institutions of learning along the entire spectrum of medical training.
MeSH term(s)	Child ; Humans ; Communicable Diseases
Language	English
Publishing date	2022-12-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2668791-4
ISSN	2048-7207 ; 2048-7193
ISSN (online)	2048-7207
ISSN	2048-7193
DOI	10.1093/jpids/piac094
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Article ; Online: Epidemiologic and Clinical Features of Mpox-Associated Deaths - United States, May 10, 2022-March 7, 2023.

Riser, Aspen P / Hanley, Allison / Cima, Michael / Lewis, Linda / Saadeh, Kayla / Alarcón, Jemma / Finn, Lauren / Kim, Moon / Adams, Jeremy / Holt, Douglas / Feldpausch, Amanda / Pavlick, Jessica / English, Andrew / Smith, Marguerite / Rehman, Tyler / Lubelchek, Ronald / Black, Stephanie / Collins, Matthew / Mounsey, Layne /

Blythe, David / Avalos, Meredith Hodach / Lee, Ellen H / Samson, Olivia / Wong, Marcia / Stokich, B Denise / Salehi, Ellen / Denny, Lynn / Waller, Kirsten / Talley, Pamela / Schuman, Julie / Fischer, Michael / White, Stephen / Davis, Kenneth / Caeser Cuyler, Ashley / Sabzwari, Rabeeya / Anderson, Robert N / Byrd, Katrina / Gold, Jeremy A W / Kindilien, Shannon / Lee, James T / O'Connor, Siobhán / O'Shea, Jesse / Salmon-Trejo, LaTweika A T / Velazquez-Kronen, Raquel / Zelaya, Carla / Bower, William / Ellington, Sascha / Gundlapalli, Adi V / McCollum, Andrea M / Zilversmit Pao, Leah / Rao, Agam K / Wong, Karen K / Guagliardo, Sarah Anne J

MMWR. Morbidity and mortality weekly report

2023 Volume 72, Issue 15, Page(s) 404–410

Abstract: As of March 7, 2023, a total of 30,235 confirmed and probable monkeypox (mpox) cases were reported in the United States, ...

Abstract	As of March 7, 2023, a total of 30,235 confirmed and probable monkeypox (mpox) cases were reported in the United States,
MeSH term(s)	Adult ; Humans ; Male ; Black or African American ; Disease Outbreaks ; Mpox (monkeypox)/mortality ; Public Health ; United States/epidemiology
Language	English
Publishing date	2023-04-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	412775-4
ISSN	1545-861X ; 0149-2195
ISSN (online)	1545-861X
ISSN	0149-2195
DOI	10.15585/mmwr.mm7215a5
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